iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Nle-070081

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ADFV01056101

Gene Name

BIRC2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSNLEG00000007166.1	ENSNLET00000009147.1	ENSNLEP00000008730.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	28.15	4.00e-47	186.00	IUUC-Dme-031819
E3 activity/RING/RING	97.57	0.00e+00	1168.00	IUUC-Hsa-045769

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Nomascus leucogenys

Protein Sequence
(Fasta)

MHKTASQRLF PGPSYQNIKS IMEDSTILSD WTNSNKQKMK YDFSCELYRM STYSTFPAGV 60
PVSERSLARA GFYYTGVNDK VKCFCCGLML DNWKLGDSPI QKHKQLYPSC CFIQNLVSAS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGATGGGGCG GCGGGCTTCG GGAGCGCCGG GGCTGATCCG AGCCGAGGGG GCCGTAGCTC 60
CTTGTCGGCG CCGCTGATTC CTGGCTCTGA GGAGGCCTCT AGGCAGCCGC GCAGCTTCCG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001370--BIR_rpt
IPR028795--C-IAP1
IPR001315--CARD
IPR011029--DEATH-like_dom
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS01282--BIR_REPEAT_1
PS50143--BIR_REPEAT_2
PS50209--CARD
PS50089--ZF_RING_2

Pfam

PF00653--BIR
PF00619--CARD

SMART

SM00238--BIR
SM00114--CARD
SM00184--RING

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005634--C:nucleus
GO:0003713--F:transcription coactivator activity
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0043066--P:negative regulation of apoptotic process
GO:0043123--P:positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:1902524--P:positive regulation of protein K48-linked ubiquitination
GO:1902523--P:positive regulation of protein K63-linked ubiquitination
GO:1902527--P:positive regulation of protein monoubiquitination
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0000209--P:protein polyubiquitination
GO:0051726--P:regulation of cell cycle
GO:0045595--P:regulation of cell differentiation
GO:0050727--P:regulation of inflammatory response
GO:0060544--P:regulation of necroptotic process
GO:0034121--P:regulation of toll-like receptor signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002369	Ailuropoda melanoleuca	86.96	0.00e+00	1070.00
IUUC-Apl-003549	Anas platyrhynchos	69.41	0.00e+00	822.00
IUUC-Aca-004515	Anolis carolinensis	68.59	0.00e+00	769.00
IUUC-Afl-008648	Aspergillus flavus	31.03	1.00e-14	75.10
IUUC-Ame-011877	Astyanax mexicanus	54.21	0.00e+00	644.00
IUUC-Bgr-012051	Blumeria graminis	33.76	2.00e-12	67.40
IUUC-Bta-012450	Bos taurus	88.25	0.00e+00	957.00
IUUC-Bci-013905	Botrytis cinerea	32.67	7.00e-17	82.00
IUUC-Cja-018895	Callithrix jacchus	94.35	0.00e+00	1120.00
IUUC-Cfa-020419	Canis familiaris	86.91	0.00e+00	1071.00
IUUC-Cpo-022048	Cavia porcellus	87.38	0.00e+00	1072.00
IUUC-Cho-024277	Choloepus hoffmanni	85.30	0.00e+00	1016.00
IUUC-Cin-025521	Ciona intestinalis	30.55	5.00e-74	271.00
IUUC-Csv-026182	Ciona savignyi	30.71	3.00e-66	246.00
IUUC-Dre-028647	Danio rerio	54.06	0.00e+00	632.00
IUUC-Dno-029509	Dasypus novemcinctus	81.40	0.00e+00	952.00
IUUC-Dor-030796	Dipodomys ordii	70.98	7.00e-97	347.00
IUUC-Dme-031819	Drosophila melanogaster	28.62	3.00e-66	245.00
IUUC-Ete-032768	Echinops telfairi	67.64	0.00e+00	721.00
IUUC-Eca-033393	Equus caballus	91.99	0.00e+00	1081.00
IUUC-Eeu-035114	Erinaceus europaeus	84.47	0.00e+00	1010.00
IUUC-Fca-036034	Felis catus	86.43	0.00e+00	1045.00
IUUC-Fal-037656	Ficedula albicollis	69.17	0.00e+00	821.00
IUUC-Gmo-038477	Gadus morhua	54.90	1.00e-176	612.00
IUUC-Gga-040601	Gallus gallus	70.33	0.00e+00	836.00
IUUC-Gac-041467	Gasterosteus aculeatus	55.82	2.00e-179	622.00
IUUC-Ggo-044857	Gorilla gorilla	97.25	0.00e+00	1163.00
IUUC-Hsa-045769	Homo sapiens	97.57	0.00e+00	1167.00
IUUC-Itr-048441	Ictidomys tridecemlineatus	90.23	0.00e+00	1096.00
IUUC-Lch-050259	Latimeria chalumnae	60.33	0.00e+00	718.00
IUUC-Loc-052169	Lepisosteus oculatus	53.82	2.00e-170	592.00
IUUC-Laf-053449	Loxodonta africana	85.62	0.00e+00	1036.00
IUUC-Meu-056241	Macropus eugenii	68.53	0.00e+00	706.00
IUUC-Mga-059947	Meleagris gallopavo	70.36	0.00e+00	839.00
IUUC-Mdo-062352	Monodelphis domestica	76.73	0.00e+00	923.00
IUUC-Mmu-064340	Mus musculus	82.26	0.00e+00	998.00
IUUC-Mpu-065890	Mustela putorius furo	87.37	0.00e+00	971.00
IUUC-Mlu-068077	Myotis lucifugus	89.22	0.00e+00	1068.00
IUUC-Opr-070561	Ochotona princeps	83.01	0.00e+00	984.00
IUUC-Ont-071776	Oreochromis niloticus	53.88	0.00e+00	634.00
IUUC-Oan-073604	Ornithorhynchus anatinus	75.25	0.00e+00	884.00
IUUC-Ocu-073963	Oryctolagus cuniculus	90.28	0.00e+00	1058.00
IUUC-Ogu-078452	Oryza glumaepatula	45.45	5.00e-07	48.90
IUUC-Oni-082044	Oryza nivara	41.82	2.00e-09	57.00
IUUC-Opu-084085	Oryza punctata	39.58	2.00e-06	46.60
IUUC-Oru-085060	Oryza rufipogon	44.19	1.00e-06	47.80
IUUC-Ola-086446	Oryzias latipes	51.92	5.00e-172	597.00
IUUC-Oga-087976	Otolemur garnettii	91.59	0.00e+00	1097.00
IUUC-Oar-090097	Ovis aries	88.46	0.00e+00	1080.00
IUUC-Ptr-091137	Pan troglodytes	97.41	0.00e+00	1165.00
IUUC-Pan-092673	Papio anubis	97.25	0.00e+00	1165.00
IUUC-Psi-092992	Pelodiscus sinensis	70.00	0.00e+00	827.00
IUUC-Pma-094277	Petromyzon marinus	37.96	1.00e-112	400.00
IUUC-Pfo-096790	Poecilia formosa	53.01	3.00e-176	611.00
IUUC-Pab-098734	Pongo abelii	97.82	0.00e+00	1125.00
IUUC-Pop-098944	Populus trichocarpa	42.59	6.00e-10	58.20
IUUC-Pca-100708	Procavia capensis	72.05	1.00e-175	609.00
IUUC-Pva-102788	Pteropus vampyrus	90.79	0.00e+00	1089.00
IUUC-Rno-105026	Rattus norvegicus	80.57	0.00e+00	963.00
IUUC-Sha-107229	Sarcophilus harrisii	71.61	0.00e+00	849.00
IUUC-Sja-107720	Schizosaccharomyces japonicus	33.56	2.00e-15	78.60
IUUC-Ssc-115804	Sus scrofa	87.30	0.00e+00	1046.00
IUUC-Tgu-116931	Taeniopygia guttata	69.24	0.00e+00	833.00
IUUC-Tru-117620	Takifugu rubripes	53.38	3.00e-179	621.00
IUUC-Tni-119683	Tetraodon nigroviridis	53.47	6.00e-179	620.00
IUUC-Tbe-127523	Tupaia belangeri	90.94	0.00e+00	1110.00
IUUC-Ttr-128954	Tursiops truncatus	87.74	0.00e+00	1057.00
IUUC-Vpa-130441	Vicugna pacos	88.67	0.00e+00	1075.00
IUUC-Xtr-132031	Xenopus tropicalis	57.77	0.00e+00	649.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence