iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mlu-067314

Ensembl Protein ID

ENSMLUP00000009701.1

UniProt Accession

G1PGE1; G1PGE1_MYOLU

Genbank Protein ID

ENSMLUP00000009701

Protein Name

Sorting nexin

Genbank Nucleotide ID

AAPE02015978

Gene Name

SNX33

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMLUG00000010647.1	ENSMLUT00000010641.1	ENSMLUP00000009701.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	6.40e-11	42.1	5	59

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 6    vqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekl 62
            ++lyd+ ++n++e ++++G+ + +   e+   gWl+g+ +  g  GlfP+ +ve +
   Q: 5    GRALYDFHSENKEEINIQQGEDLVIF-SENSLDGWLQGQ-NSLGETGLFPASYVEII 59
           689**********************9.888889*****7.899***********976 PP

Organism

Myotis lucifugus

Protein Sequence
(Fasta)

MALKGRALYD FHSENKEEIN IQQGEDLVIF SENSLDGWLQ GQNSLGETGL FPASYVEIIS 60
SGTSFNHADY SSSSAGSPGT QVSMYDSSSV ANLASGGGSG FLSNQGSFEE DDDDDWDDWD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCACTAA AAGGCCGAGC CCTCTATGAC TTCCACAGTG AGAACAAAGA GGAAATCAAC 60
ATCCAGCAGG GTGAGGATTT GGTCATCTTC AGTGAGAACT CATTGGATGG TTGGCTGCAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0968--Cytoplasmic vesicle
KW-0472--Membrane
KW-1185--Reference proteome

Interpro

IPR027267--AH/BAR-dom
IPR001683--Phox
IPR001452--SH3_domain
IPR028642--SNX33
IPR014536--Snx9_subfam
IPR019497--Sorting_nexin_WASP-bd-dom

PROSITE

PS50195--PX
PS50002--SH3

Pfam

PF10456--BAR_3_WASP_bdg
PF00787--PX
PF14604--SH3_9

SMART

SM00312--PX
SM00326--SH3

Gene Ontology

GO:0030659--C:cytoplasmic vesicle membrane
GO:0005829--C:cytosol
GO:0019898--C:extrinsic component of membrane
GO:0035091--F:phosphatidylinositol binding
GO:0036089--P:cleavage furrow formation
GO:0016197--P:endosomal transport
GO:0007032--P:endosome organization
GO:0006886--P:intracellular protein transport
GO:0044351--P:macropinocytosis
GO:0000281--P:mitotic cytokinesis
GO:0007067--P:mitotic nuclear division
GO:0045806--P:negative regulation of endocytosis
GO:2000009--P:negative regulation of protein localization to cell surface
GO:0097320--P:plasma membrane tubulation
GO:0051044--P:positive regulation of membrane protein ectodomain proteolysis
GO:2000010--P:positive regulation of protein localization to cell surface
GO:0017038--P:protein import

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Cel-018605	Caenorhabditis elegans	38.31	2.00e-77	283.00
IUUC-Cin-025695	Ciona intestinalis	41.88	1.00e-102	367.00
IUUC-Csv-025870	Ciona savignyi	41.69	9.00e-96	344.00
IUUC-Cne-026820	Cryptococcus neoformans	41.38	1.00e-08	55.50
IUUC-Dme-031845	Drosophila melanogaster	32.58	2.00e-81	296.00
IUUC-Lch-050438	Latimeria chalumnae	51.34	4.00e-167	581.00
IUUC-Mor-056954	Magnaporthe oryzae	33.90	1.00e-06	48.90
IUUC-Mvi-060548	Microbotryum violaceum	48.15	3.00e-09	58.20

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence