iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Itr-048536

Ensembl Protein ID

ENSSTOP00000012233.2

UniProt Accession

I3MLE9; I3MLE9_ICTTR

Genbank Protein ID

ENSSTOP00000012233

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGTP01101489

Gene Name

SQSTM1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSTOG00000013654.2	ENSSTOT00000013653.2	ENSSTOP00000012233.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
ULD/UDP/UFD/PB1	2.30e-18	66.2	22	102

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

ULD/UDP/UFD/PB1

   S: 3    rvkvsykgeirsfaldlekpgkfedLlkavrt.ltelknsevalkYeDedGDlvtlksDedldkavsllaskksllrlliqkk 84
           r+ +++++e+++ a+++++pg +e+Ll++v++ +++l+   ++ +Y+DedGDlv+++sDe+l++a+s+   k++++r++i++k
   Q: 22   RFSFCFSPEPEAEAEAAAGPGPCERLLSRVAAlFPALRPGGFQAHYRDEDGDLVAFSSDEELTMAMSY--VKEDIFRIYIKEK 102
           899*****************************999********************************7..9*********975 PP

Organism

Ictidomys tridecemlineatus

Protein Sequence
(Fasta)

MASLTVKAYL LGKEEAAREI RRFSFCFSPE PEAEAEAAAG PGPCERLLSR VAALFPALRP 60
GGFQAHYRDE DGDLVAFSSD EELTMAMSYV KEDIFRIYIK EKKECRRDHR APCAQEAPRS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TAGATCTGTG ATAATGGCGT CGCTCACCGT GAAGGCCTAC CTTTTGGGCA AGGAGGAAGC 60
AGCGCGTGAG ATCCGCCGCT TCAGCTTCTG TTTCAGCCCT GAGCCTGAGG CTGAAGCCGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR000270--PB1_dom
IPR033741--SQSTM_UBA
IPR015940--UBA
IPR009060--UBA-like
IPR000433--Znf_ZZ

PROSITE

PS51745--PB1
PS50030--UBA
PS01357--ZF_ZZ_1
PS50135--ZF_ZZ_2

Pfam

PF00564--PB1
PF16577--UBA_5
PF00569--ZZ

SMART

SM00666--PB1
SM00165--UBA
SM00291--ZnF_ZZ

Gene Ontology

GO:0016235--C:aggresome
GO:0044753--C:amphisome
GO:0044754--C:autolysosome
GO:0005829--C:cytosol
GO:0070062--C:extracellular exosome
GO:0000932--C:P-body
GO:0016605--C:PML body
GO:0000407--C:pre-autophagosomal structure
GO:0097225--C:sperm midpiece
GO:0008270--F:zinc ion binding
GO:0006914--P:autophagy
GO:0044130--P:negative regulation of growth of symbiont in host
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0098779--P:positive regulation of macromitophagy in response to mitochondrial depolarization
GO:0043122--P:regulation of I-kappaB kinase/NF-kappaB signaling
GO:0061635--P:regulation of protein complex stability

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001367	Ailuropoda melanoleuca	91.13	5.00e-174	603.00
IUUC-Apl-003897	Anas platyrhynchos	58.71	6.00e-119	420.00
IUUC-Aca-004699	Anolis carolinensis	47.60	2.00e-96	345.00
IUUC-Ame-010982	Astyanax mexicanus	43.88	3.00e-64	238.00
IUUC-Bta-012634	Bos taurus	90.23	0.00e+00	752.00
IUUC-Cel-018540	Caenorhabditis elegans	39.06	1.00e-09	58.20
IUUC-Cja-019684	Callithrix jacchus	91.59	0.00e+00	742.00
IUUC-Cfa-020573	Canis familiaris	85.84	9.00e-143	499.00
IUUC-Cpo-021425	Cavia porcellus	80.86	0.00e+00	630.00
IUUC-Csa-023968	Chlorocebus sabaeus	91.82	0.00e+00	725.00
IUUC-Cho-024596	Choloepus hoffmanni	84.52	9.00e-54	203.00
IUUC-Cin-025557	Ciona intestinalis	38.38	1.00e-12	66.60
IUUC-Csv-025974	Ciona savignyi	26.79	5.00e-15	74.70
IUUC-Cne-027045	Cryptococcus neoformans	50.98	7.00e-10	59.70
IUUC-Dre-028621	Danio rerio	43.49	8.00e-95	340.00
IUUC-Dno-029060	Dasypus novemcinctus	87.61	0.00e+00	737.00
IUUC-Dor-030547	Dipodomys ordii	90.84	5.00e-139	487.00
IUUC-Dme-031659	Drosophila melanogaster	40.30	4.00e-09	56.20
IUUC-Ete-033201	Echinops telfairi	79.09	1.00e-163	568.00
IUUC-Eca-033456	Equus caballus	91.38	0.00e+00	691.00
IUUC-Eeu-035157	Erinaceus europaeus	84.49	9.00e-173	598.00
IUUC-Fca-035403	Felis catus	90.77	0.00e+00	720.00
IUUC-Fal-036798	Ficedula albicollis	56.93	2.00e-135	475.00
IUUC-Gmo-039619	Gadus morhua	39.48	8.00e-47	180.00
IUUC-Gga-040137	Gallus gallus	56.08	4.00e-133	467.00
IUUC-Gac-042410	Gasterosteus aculeatus	45.78	6.00e-98	350.00
IUUC-Ggo-044690	Gorilla gorilla	93.64	0.00e+00	734.00
IUUC-Hsa-046390	Homo sapiens	93.41	0.00e+00	731.00
IUUC-Lch-049658	Latimeria chalumnae	47.45	5.00e-112	397.00
IUUC-Loc-052589	Lepisosteus oculatus	46.52	3.00e-109	388.00
IUUC-Laf-053746	Loxodonta africana	80.94	0.00e+00	638.00
IUUC-Mcc-055635	Macaca mulatta	91.82	0.00e+00	736.00
IUUC-Meu-056528	Macropus eugenii	52.51	2.00e-106	378.00
IUUC-Mga-059458	Meleagris gallopavo	58.15	5.00e-120	424.00
IUUC-Mmr-061539	Microcebus murinus	87.70	3.00e-140	490.00
IUUC-Mdo-063083	Monodelphis domestica	64.18	1.00e-152	532.00
IUUC-Mmu-063589	Mus musculus	90.50	0.00e+00	757.00
IUUC-Mpu-065727	Mustela putorius furo	89.49	0.00e+00	637.00
IUUC-Mlu-067026	Myotis lucifugus	88.53	0.00e+00	644.00
IUUC-Nle-069356	Nomascus leucogenys	67.19	5.00e-123	434.00
IUUC-Opr-071091	Ochotona princeps	69.64	1.00e-95	343.00
IUUC-Ont-071864	Oreochromis niloticus	46.64	3.00e-102	364.00
IUUC-Oan-073308	Ornithorhynchus anatinus	63.05	8.00e-135	473.00
IUUC-Ocu-074110	Oryctolagus cuniculus	92.27	0.00e+00	741.00
IUUC-Ola-086944	Oryzias latipes	45.70	1.00e-40	158.00
IUUC-Oga-088869	Otolemur garnettii	91.03	0.00e+00	744.00
IUUC-Oar-089857	Ovis aries	89.87	0.00e+00	653.00
IUUC-Ptr-091640	Pan troglodytes	93.64	0.00e+00	735.00
IUUC-Pan-092831	Papio anubis	91.70	0.00e+00	728.00
IUUC-Psi-093925	Pelodiscus sinensis	55.88	4.00e-129	454.00
IUUC-Pma-094576	Petromyzon marinus	31.68	3.00e-32	132.00
IUUC-Pfo-097297	Poecilia formosa	44.35	2.00e-91	328.00
IUUC-Pab-098725	Pongo abelii	84.55	0.00e+00	649.00
IUUC-Pca-101106	Procavia capensis	90.00	0.00e+00	710.00
IUUC-Pva-102710	Pteropus vampyrus	87.95	0.00e+00	644.00
IUUC-Rno-105539	Rattus norvegicus	91.40	0.00e+00	772.00
IUUC-Sha-107469	Sarcophilus harrisii	61.82	9.00e-123	432.00
IUUC-Ssc-115526	Sus scrofa	92.50	0.00e+00	736.00
IUUC-Tgu-117194	Taeniopygia guttata	60.00	4.00e-118	417.00
IUUC-Tru-117896	Takifugu rubripes	48.54	7.00e-103	367.00
IUUC-Tni-119943	Tetraodon nigroviridis	47.52	4.00e-91	327.00
IUUC-Ttr-128676	Tursiops truncatus	91.82	0.00e+00	762.00
IUUC-Vda-129812	Verticillium dahliae	46.94	2.00e-06	47.40
IUUC-Vpa-130319	Vicugna pacos	93.00	4.00e-55	207.00
IUUC-Xtr-132907	Xenopus tropicalis	54.15	1.00e-129	456.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence