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Basic Information Integrated Annotations
Tag Content
iUUCD ID IUUC-Ath-006902
UUCD1 version UUC-ArT-01441
Ensembl Protein ID AT1G76260.1
UniProt Accession Q6NPN9; Q67YQ8; Q9SFW2; Q9SGQ8; DWA2_ARATH
Genbank Protein ID AAF17630.1; AAF16674.1; AEE35816.1; AAR24658.1; BAD44173.1; BAD43202.1; BAD44413.1
Protein Name WD repeat-containing protein DWA2; Protein DWD HYPERSENSITIVE TO ABA 2
Genbank Nucleotide ID AC009978; AC012394; CP002684; BT010880; AK176410; AK175439; AK176650
Gene Name DWA2; At1g76260; F15M4.24; T23E18.19
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
AT1G76260 AT1G76260.1 AT1G76260.1
Annotation
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpress
DNA & RNA Element
TRANSFAC
Protein-protein Interaction
iRefIndexPINAHINTMentha
Protein Expression/Proteomics
GPMDB
Status Reviewed
Details
Family Domain References (PMIDs)
E3 adaptor/Cullin RING/DCX/DWD WD_repeat 20525848
Classification
Family E-value Score Start End
E3 adaptor/Cullin RING/DCX/DWD 6.30e-12 46.2 313 340
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/DCX/DWD
   S: 3    tdsvtclaf..sd.tllvsGsdDgtikv 27
           +dsv++la+   + ++++s s+Dg + +
   Q: 313  EDSVYGLAWssREpWIFASLSYDGRVVI 340
           699******9855799*********987 PP
   
Organism Arabidopsis thaliana
Functional Description
(View)

Functional Description


     Component of the CUL4-RBX1-DDB1-DWA1/DWA2 E3 ubiquitin-protein ligase complex that acts as negative regulator in abscisic acid (ABA) signaling. May function as the substrate recognition module within this complex leading to ABI5 degradation. Functionally redundant with DWA1.
 Component of the CUL4-RBX1-DDB1-DWA1/DWA2 E3 ubiquitin-protein ligase complex that acts as negative regulator in abscisic acid (ABA) signaling. May function as the substrate recognition module within this complex leading to ABI5 degradation. Functionally redundant with DWA1.
Protein Sequence
(Fasta)
MQGGSSGIGY GLKYQARCIS DVKADRDHTS FLTGTLSLKE ENEVHLLRLS SGGSELLCEG 60
LFSHPNEIWD LASSPFDQRI FSTVFSTGDS YGAAIWQIPE PYGQSNSSTL ECVASLDAHV 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Ath-006902|E3,WD_repeat|Arabidopsis thaliana
Please wait for a moment...
Nucleotide Sequence
(Fasta)
CAAAAATAAA ACAGTTTATG ATTCAGTTTG TAAAAGTGGG CTTATTTAAA TGAATATTGG 60
CCCATTAGTA TCATCTTCAC GAAACCCAGC AAAATCAGAG AGCGGCAAAT CGTTGAAGAG 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Ath-006902|E3,WD_repeat|Arabidopsis thaliana
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0938--Abscisic acid signaling pathway
KW-0181--Complete proteome
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0677--Repeat
KW-0833--Ubl conjugation pathway
KW-0853--WD repeat
Interpro

IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom
PROSITE

PS50294--WD_REPEATS_REGION
Pfam

PF00400--WD40
SMART

SM00320--WD40
Gene Ontology

GO:0080008--C:Cul4-RING E3 ubiquitin ligase complex
GO:0005634--C:nucleus
GO:0009738--P:abscisic acid-activated signaling pathway
GO:0009788--P:negative regulation of abscisic acid-activated signaling pathway
GO:0016567--P:protein ubiquitination
KEGG ath:AT1G76260
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aly-006294 Arabidopsis lyrata 96.57 0.00e+00 659.00
IUUC-Bta-013035 Bos taurus 34.23 2.00e-51 195.00
IUUC-Bra-017885 Brassica rapa 93.43 0.00e+00 651.00
IUUC-Cfa-020214 Canis familiaris 34.14 5.00e-48 184.00
IUUC-Cpo-021363 Cavia porcellus 33.69 3.00e-47 181.00
IUUC-Csa-023240 Chlorocebus sabaeus 33.60 1.00e-48 186.00
IUUC-Cho-024713 Choloepus hoffmanni 32.32 2.00e-44 172.00
IUUC-Cin-025678 Ciona intestinalis 31.40 1.00e-42 166.00
IUUC-Csv-026022 Ciona savignyi 31.78 2.00e-42 165.00
IUUC-Ete-032575 Echinops telfairi 28.57 8.00e-27 113.00
IUUC-Eca-034323 Equus caballus 32.71 1.00e-32 132.00
IUUC-Eeu-035217 Erinaceus europaeus 28.62 4.00e-26 111.00
IUUC-Fca-035709 Felis catus 32.65 4.00e-38 151.00
IUUC-Gac-041368 Gasterosteus aculeatus 28.42 1.00e-21 96.70
IUUC-Ggo-044513 Gorilla gorilla 31.50 2.00e-45 176.00
IUUC-Lch-049696 Latimeria chalumnae 32.81 2.00e-51 195.00
IUUC-Loc-052440 Lepisosteus oculatus 34.21 5.00e-53 201.00
IUUC-Laf-054088 Loxodonta africana 34.77 4.00e-48 184.00
IUUC-Mmr-061706 Microcebus murinus 33.60 3.00e-51 195.00
IUUC-Mdo-062736 Monodelphis domestica 33.87 8.00e-49 186.00
IUUC-Mmu-064265 Mus musculus 33.51 1.00e-51 196.00
IUUC-Mpu-066514 Mustela putorius furo 34.41 4.00e-51 194.00
IUUC-Nle-069307 Nomascus leucogenys 29.35 6.00e-40 157.00
IUUC-Opr-070283 Ochotona princeps 30.09 3.00e-30 125.00
IUUC-Ont-072532 Oreochromis niloticus 33.07 7.00e-50 190.00
IUUC-Oan-073222 Ornithorhynchus anatinus 32.46 1.00e-43 169.00
IUUC-Ola-086694 Oryzias latipes 30.49 3.00e-49 188.00
IUUC-Oga-088180 Otolemur garnettii 33.57 2.00e-36 145.00
IUUC-Ptr-091053 Pan troglodytes 32.80 1.00e-44 173.00
IUUC-Pan-091918 Papio anubis 33.33 1.00e-47 183.00
IUUC-Pma-094439 Petromyzon marinus 30.05 8.00e-45 173.00
IUUC-Pfo-096127 Poecilia formosa 34.30 2.00e-50 192.00
IUUC-Pva-103228 Pteropus vampyrus 32.08 5.00e-46 177.00
IUUC-Sha-106940 Sarcophilus harrisii 34.49 2.00e-50 192.00
IUUC-Sar-113084 Sorex araneus 32.06 4.00e-19 88.20
IUUC-Ssc-115385 Sus scrofa 33.86 1.00e-49 189.00
IUUC-Tsy-119435 Tarsius syrichta 30.33 2.00e-43 169.00
IUUC-Tni-120311 Tetraodon nigroviridis 28.76 2.00e-34 139.00
IUUC-Ttr-128706 Tursiops truncatus 31.70 6.00e-29 120.00
IUUC-Xtr-131950 Xenopus tropicalis 34.14 1.00e-52 199.00
Created Date 25-Jun-2017

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