iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Tru-118490

UUCD1 version

UUC-TaR-00457

Ensembl Protein ID

ENSTRUP00000022433.1

UniProt Accession

H2TCP1; H2TCP1_TAKRU

Protein Name

Uncharacterized protein

Gene Name

klhl21

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTRUG00000008923.1	ENSTRUT00000022525.1	ENSTRUP00000022432.1
ENSTRUG00000008923.1	ENSTRUT00000022526.1	ENSTRUP00000022433.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	1.80e-18	67.8	39	103
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	6.40e-10	38.2	137	167

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 2    DvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgklde 67
           Dv+l+ +g+ef++h+ vLaa+S +F+a+f++ l+es   ++v++++v++e +  l++F+Ytg+++ 
   Q: 39   DVTLCAEGREFRCHRTVLAAASTYFRAMFTGTLRESV-MDCVVLHEVSAELLGLLVDFCYTGRVTV 103
           9***********************************9.*************************976 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 1    leNclgilrfAdlydcpdLkdaaldfilkhF 31
           ++Ncl+i +fA++y c++L+ +a++f+lk++
   Q: 137  VSNCLEIQDFAEAYACRELAASARRFVLKNM 167
           69***************************95 PP

Organism

Takifugu rubripes

Protein Sequence
(Fasta)

MERPGLQTQP STLPFFDTAH AFNLLRGIHE LRAEQKFFDV TLCAEGREFR CHRTVLAAAS 60
TYFRAMFTGT LRESVMDCVV LHEVSAELLG LLVDFCYTGR VTVTQDNVDV LLKTADLFQF 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGAGCGGC CCGGCCTGCA GACACAGCCA TCCACCCTGC CGTTTTTCGA CACGGCCCAC 60
GCCTTCAACC TGCTGCGGGG GATCCACGAA CTGCGCGCCG AGCAAAAGTT TTTCGACGTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR017096--BTB-kelch_protein
IPR000210--BTB/POZ_dom
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0016567--P:protein ubiquitination

KEGG

tru:101071032

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001782	Ailuropoda melanoleuca	66.73	0.00e+00	685.00
IUUC-Apl-003189	Anas platyrhynchos	73.91	2.00e-125	441.00
IUUC-Ame-011774	Astyanax mexicanus	90.83	0.00e+00	660.00
IUUC-Bta-012367	Bos taurus	70.60	0.00e+00	823.00
IUUC-Cja-019501	Callithrix jacchus	65.95	0.00e+00	746.00
IUUC-Cfa-020550	Canis familiaris	70.33	0.00e+00	826.00
IUUC-Cpo-022072	Cavia porcellus	70.25	0.00e+00	809.00
IUUC-Csa-023364	Chlorocebus sabaeus	71.71	0.00e+00	754.00
IUUC-Cin-025253	Ciona intestinalis	42.86	2.00e-148	518.00
IUUC-Csv-025871	Ciona savignyi	43.14	1.00e-153	536.00
IUUC-Dre-028694	Danio rerio	88.34	0.00e+00	1092.00
IUUC-Dno-029082	Dasypus novemcinctus	72.54	0.00e+00	726.00
IUUC-Dor-030680	Dipodomys ordii	69.89	0.00e+00	818.00
IUUC-Ete-032315	Echinops telfairi	72.44	0.00e+00	728.00
IUUC-Eca-033570	Equus caballus	79.13	2.00e-156	544.00
IUUC-Eeu-035067	Erinaceus europaeus	80.72	9.00e-111	394.00
IUUC-Fal-037103	Ficedula albicollis	67.89	0.00e+00	742.00
IUUC-Gmo-039420	Gadus morhua	86.97	0.00e+00	1090.00
IUUC-Gga-040161	Gallus gallus	67.14	0.00e+00	724.00
IUUC-Gac-041755	Gasterosteus aculeatus	91.38	0.00e+00	1121.00
IUUC-Ggo-044899	Gorilla gorilla	70.25	0.00e+00	824.00
IUUC-Hsa-045834	Homo sapiens	70.25	0.00e+00	823.00
IUUC-Itr-048413	Ictidomys tridecemlineatus	70.42	0.00e+00	823.00
IUUC-Lch-050338	Latimeria chalumnae	74.58	0.00e+00	957.00
IUUC-Loc-051780	Lepisosteus oculatus	85.59	0.00e+00	1066.00
IUUC-Laf-053725	Loxodonta africana	75.58	0.00e+00	629.00
IUUC-Mcc-055032	Macaca mulatta	68.65	0.00e+00	706.00
IUUC-Meu-056661	Macropus eugenii	77.55	0.00e+00	640.00
IUUC-Mga-059821	Meleagris gallopavo	74.09	3.00e-110	390.00
IUUC-Mdo-062095	Monodelphis domestica	68.82	0.00e+00	719.00
IUUC-Mmu-063138	Mus musculus	70.77	0.00e+00	830.00
IUUC-Mpu-066386	Mustela putorius furo	82.13	1.00e-147	515.00
IUUC-Mlu-067807	Myotis lucifugus	80.43	7.00e-159	553.00
IUUC-Nle-069181	Nomascus leucogenys	69.37	0.00e+00	807.00
IUUC-Opr-070658	Ochotona princeps	70.95	0.00e+00	839.00
IUUC-Ont-072209	Oreochromis niloticus	91.94	0.00e+00	1132.00
IUUC-Oan-072861	Ornithorhynchus anatinus	77.23	9.00e-96	342.00
IUUC-Ocu-074631	Oryctolagus cuniculus	64.08	0.00e+00	712.00
IUUC-Ola-087553	Oryzias latipes	88.87	0.00e+00	1089.00
IUUC-Oga-088782	Otolemur garnettii	70.42	0.00e+00	823.00
IUUC-Oar-089634	Ovis aries	70.25	0.00e+00	820.00
IUUC-Ptr-091259	Pan troglodytes	73.85	0.00e+00	641.00
IUUC-Pan-091734	Papio anubis	70.42	0.00e+00	825.00
IUUC-Psi-092979	Pelodiscus sinensis	67.07	0.00e+00	766.00
IUUC-Pma-094459	Petromyzon marinus	49.59	6.00e-117	414.00
IUUC-Pfo-097446	Poecilia formosa	92.14	0.00e+00	1128.00
IUUC-Pab-098765	Pongo abelii	68.81	0.00e+00	827.00
IUUC-Pva-102730	Pteropus vampyrus	67.08	0.00e+00	774.00
IUUC-Rno-104972	Rattus norvegicus	71.13	0.00e+00	834.00
IUUC-Sar-112931	Sorex araneus	30.44	3.00e-75	276.00
IUUC-Ssc-115869	Sus scrofa	68.84	0.00e+00	710.00
IUUC-Tgu-116562	Taeniopygia guttata	67.90	0.00e+00	763.00
IUUC-Tsy-119071	Tarsius syrichta	30.27	2.00e-74	273.00
IUUC-Tni-119898	Tetraodon nigroviridis	92.80	0.00e+00	1126.00
IUUC-Ttr-128976	Tursiops truncatus	79.82	1.00e-109	390.00
IUUC-Xtr-132876	Xenopus tropicalis	73.81	0.00e+00	905.00
IUUC-Xma-133540	Xiphophorus maculatus	91.98	0.00e+00	1131.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence