iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Dse-031467

Ensembl Protein ID

EME42196

UniProt Accession

N1PLN7; N1PLN7_DOTSN

Genbank Protein ID

EME42196.1

Protein Name

Ubiquitinyl hydrolase 1

Genbank Nucleotide ID

KB446541

Gene Name

DOTSEDRAFT_73122

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
DOTSEDRAFT_73122	EME42196	EME42196

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	1.50e-51	174.9	304	798
UBD/Alpha-Helix/UBA	2.70e-17	61.7	668	707

Active Site

Position(s)	Description	Evidence
313	Nucleophile	{ECO:0000256\|PIRSR:PIRSR016308-1}
759	Proton acceptor	{ECO:0000256\|PIRSR:PIRSR016308-1}

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeel.................w.kskkkavsprellkalkkeaee 83
           tGlkNlgNtCY+ Sv+Q+L+++pe+++ +++   e l+ +  ++p +++  +l+kl   l                 + k  +k  +p +l++ ++k + e
   Q: 304  TGLKNLGNTCYLASVVQSLFSMPEFQSRYNR-PDEPLPPT--SKPAEDIEIQLRKLADGLlsgryskpdsdvfpqnsVeKAYQKGLAPAMLKHLVGKGHAE 401
           7******************************.77777765..6899999999999999996666666666655554414666669**************** PP
   S: 84   fsgyeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpvpgkeetkk 184
           fs+++qqDa E+l ++l+ ++++                       +    + ++    +d F++ ++++++cl+c++v  r++++  +s++vp k+  k 
   Q: 402  FSTMRQQDAFELLLHVLKLVSRSQ----------------------QGAAGQYEKVFDPVDAFRFCMEQKLQCLSCKKVRFRQDDMENISVAVPIKRLPKD 480
           **********************99......................223344444555789*********************************9998777 PP
   S: 185  e...................slqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefple.Ldlspfc 265
           +                   +l++cL++ft++e +e    + c+ c++k   +k+  +k++P vL ++  Rf+     ++++k +  v + +e +d++ + 
   Q: 481  PnamdtngdkdgmkeefepvTLKQCLDDFTAPEIVE----LTCSGCNSKG-FSKQSLFKTFPTVLAVNARRFEI--VSWVPTKQDVPVIVGDEeFDMEAYR 574
           699999*****************************9....9******999.9********************66..66************9999******* PP
   S: 266  ts..........................................................................................peekqke.. 274
           ++                                                                                                +  
   Q: 575  SKgkqpgeeelsdgqdagagavaaadrfvpnetalemlmgmgfprvrcekalnatgnsdaevaagwlfehmedpdidtplealapapaaggrA-----Ddp 670
           **7777777777777776666666666666666666666666666666666666655555555555555555555555555555555555550.....055 PP
   S: 275  ....................................................................kkkYeLiavvvHsG.slssGHYvayvknekgkW 306
                                                                               + k++L+++v+H+G s++ GHYva++k+ +g W
   Q: 671  qkieslgnmgfsvpqarqalketdgdieravdwlfshpdavgdfgddamptsseavpataekvvddtkPAKFSLTSIVCHKGsSIHAGHYVAFIKKPEG-W 770
           55555555555555555555666666666666666666666666666666666666777777777787****************************555.* PP
   S: 307  llfdDskVtevkeeevleetgstaYvlfYkr 337
           +lf+D+kV      +v+e++ + aY++f++r
   Q: 771  VLFNDEKVALG--GDVEEMK-KFAYIYFFRR 798
           ********988..4444433.68******97 PP

UBD/Alpha-Helix/UBA

   S: 2    ededkleqlveMGFdreealqaLraannnleaAveyLldg 41
           +d +k+e l +MGF+  +a+qaL ++++++e+Av++L+++
   Q: 668  DDPQKIESLGNMGFSVPQARQALKETDGDIERAVDWLFSH 707
           5899**********************************97 PP

Organism

Dothistroma septosporum

Protein Sequence
(Fasta)

MASCPHVAKA DIHPPKPTDN VYREDCTICF DSSEDPAGLD VCLHCYNGGC AGDRHHSKLH 60
AQHSNHPLAV NIKRTRKRKQ RDENEPPNKI NKLEIKAELD EDRYDTATDI KCLECGVGGL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTGGAGAAGT ACACCAACAT TGCTCAGCCT CGTCTTGGAT CTTTCCTGGT CATCTCCTGA 60
CACTCTATCC ACAAGTCGTC CCCAAGATGG CGTCCTGCCC GCACGTGGCA AAGGCCGACA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0479--Metal-binding
KW-0645--Protease
KW-1185--Reference proteome
KW-0788--Thiol protease
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001394--Peptidase_C19_UCH
IPR015940--UBA
IPR009060--UBA-like
IPR016652--Ubiquitinyl_hydrolase
IPR018200--USP_CS
IPR028889--USP_dom
IPR013083--Znf_RING/FYVE/PHD
IPR001607--Znf_UBP

PROSITE

PS50030--UBA
PS00972--USP_1
PS00973--USP_2
PS50235--USP_3
PS50271--ZF_UBP

Pfam

PF00627--UBA
PF00443--UCH
PF02148--zf-UBP

SMART

SM00165--UBA
SM00290--ZnF_UBP

Gene Ontology

GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0008270--F:zinc ion binding
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000394	Aegilops tauschii	32.94	2.00e-96	345.00
IUUC-Aml-002104	Ailuropoda melanoleuca	36.11	7.00e-131	459.00
IUUC-Atr-002580	Amborella trichopoda	32.83	2.00e-102	365.00
IUUC-Apl-003774	Anas platyrhynchos	36.22	9.00e-128	449.00
IUUC-Aca-005368	Anolis carolinensis	35.81	3.00e-133	467.00
IUUC-Aly-005727	Arabidopsis lyrata	35.45	2.00e-115	407.00
IUUC-Ath-006974	Arabidopsis thaliana	35.41	3.00e-115	407.00
IUUC-Ago-007890	Ashbya gossypii	30.39	2.00e-98	351.00
IUUC-Acl-008057	Aspergillus clavatus	51.75	0.00e+00	820.00
IUUC-Afl-008547	Aspergillus flavus	52.28	0.00e+00	706.00
IUUC-Afu-008805	Aspergillus fumigatus	49.87	0.00e+00	717.00
IUUC-Ani-009441	Aspergillus nidulans	48.99	0.00e+00	647.00
IUUC-Ang-009720	Aspergillus niger	52.66	0.00e+00	822.00
IUUC-Aor-010111	Aspergillus oryzae	52.97	0.00e+00	851.00
IUUC-Ate-010531	Aspergillus terreus	49.57	0.00e+00	738.00
IUUC-Ame-011470	Astyanax mexicanus	32.24	1.00e-108	385.00
IUUC-Bgr-012183	Blumeria graminis	53.04	0.00e+00	826.00
IUUC-Bta-013179	Bos taurus	36.24	8.00e-131	459.00
IUUC-Bci-013858	Botrytis cinerea	56.86	0.00e+00	910.00
IUUC-Bdi-014904	Brachypodium distachyon	34.19	2.00e-106	378.00
IUUC-Bol-015296	Brassica oleracea	35.78	2.00e-116	411.00
IUUC-Bra-017939	Brassica rapa	35.87	2.00e-118	418.00
IUUC-Cel-018625	Caenorhabditis elegans	30.91	2.00e-83	301.00
IUUC-Cja-019063	Callithrix jacchus	36.05	4.00e-131	460.00
IUUC-Cfa-020976	Canis familiaris	37.05	1.00e-134	472.00
IUUC-Cpo-022265	Cavia porcellus	36.77	2.00e-133	468.00
IUUC-Cre-022640	Chlamydomonas reinhardtii	32.34	6.00e-65	239.00
IUUC-Csa-024177	Chlorocebus sabaeus	36.39	5.00e-121	427.00
IUUC-Cho-024702	Choloepus hoffmanni	34.08	4.00e-74	270.00
IUUC-Cin-025411	Ciona intestinalis	33.74	6.00e-105	373.00
IUUC-Csv-026347	Ciona savignyi	31.74	3.00e-106	377.00
IUUC-Cgl-026667	Colletotrichum gloeosporioides	55.65	0.00e+00	826.00
IUUC-Cne-026831	Cryptococcus neoformans	45.54	0.00e+00	633.00
IUUC-Cme-027335	Cyanidioschyzon merolae	36.18	2.00e-62	233.00
IUUC-Dre-027982	Danio rerio	34.03	3.00e-106	378.00
IUUC-Dno-029034	Dasypus novemcinctus	36.57	2.00e-132	465.00
IUUC-Dor-030479	Dipodomys ordii	37.23	1.00e-56	213.00
IUUC-Dme-032075	Drosophila melanogaster	33.73	2.00e-109	388.00
IUUC-Ete-032865	Echinops telfairi	33.84	3.00e-113	401.00
IUUC-Eca-034059	Equus caballus	36.11	8.00e-130	456.00
IUUC-Eeu-035304	Erinaceus europaeus	37.39	2.00e-119	421.00
IUUC-Fca-035515	Felis catus	36.34	2.00e-131	461.00
IUUC-Fal-037271	Ficedula albicollis	36.62	2.00e-123	434.00
IUUC-Fox-037745	Fusarium oxysporum	56.41	0.00e+00	883.00
IUUC-Fso-038158	Fusarium solani	59.15	0.00e+00	907.00
IUUC-Gmo-039071	Gadus morhua	32.93	2.00e-107	382.00
IUUC-Ggr-040098	Gaeumannomyces graminis	55.32	0.00e+00	813.00
IUUC-Gga-040635	Gallus gallus	35.75	1.00e-131	462.00
IUUC-Gac-042528	Gasterosteus aculeatus	34.57	4.00e-112	397.00
IUUC-Gma-043614	Glycine max	34.06	6.00e-110	390.00
IUUC-Ggo-044602	Gorilla gorilla	36.34	1.00e-131	461.00
IUUC-Hsa-045959	Homo sapiens	36.34	1.00e-131	461.00
IUUC-Hvu-047563	Hordeum vulgare	38.33	5.00e-102	363.00
IUUC-Itr-048712	Ictidomys tridecemlineatus	36.26	3.00e-131	461.00
IUUC-Kpa-049156	Komagataella pastoris	39.29	2.00e-165	574.00
IUUC-Lch-049648	Latimeria chalumnae	33.93	9.00e-121	426.00
IUUC-Lpe-051523	Leersia perrieri	33.17	2.00e-106	378.00
IUUC-Loc-052072	Lepisosteus oculatus	32.00	1.00e-106	379.00
IUUC-Lma-053216	Leptosphaeria maculans	62.95	0.00e+00	950.00
IUUC-Laf-054327	Loxodonta africana	36.23	2.00e-131	461.00
IUUC-Mcc-055443	Macaca mulatta	36.46	2.00e-132	464.00
IUUC-Meu-056298	Macropus eugenii	36.18	9.00e-91	326.00
IUUC-Mor-057106	Magnaporthe oryzae	54.98	0.00e+00	851.00
IUUC-Mpo-057589	Magnaporthe poae	55.94	0.00e+00	822.00
IUUC-Mtr-058680	Medicago truncatula	35.55	2.00e-114	404.00
IUUC-Mla-058903	Melampsora laricipopulina	42.27	9.00e-171	592.00
IUUC-Mga-059669	Meleagris gallopavo	35.08	1.00e-124	438.00
IUUC-Mvi-060476	Microbotryum violaceum	42.33	3.00e-161	560.00
IUUC-Mmr-060575	Microcebus murinus	36.47	7.00e-132	462.00
IUUC-Mdo-062183	Monodelphis domestica	36.55	4.00e-134	470.00
IUUC-Mmu-063592	Mus musculus	36.65	3.00e-133	468.00
IUUC-Mac-065634	Musa acuminata	32.77	6.00e-103	367.00
IUUC-Mpu-066082	Mustela putorius furo	37.31	3.00e-134	471.00
IUUC-Mlu-067345	Myotis lucifugus	36.43	1.00e-131	462.00
IUUC-Nfi-068558	Neosartorya fischeri	52.27	0.00e+00	778.00
IUUC-Ncr-068960	Neurospora crassa	55.75	0.00e+00	836.00
IUUC-Nle-070173	Nomascus leucogenys	36.94	7.00e-134	469.00
IUUC-Opr-070556	Ochotona princeps	36.59	9.00e-133	466.00
IUUC-Ont-071502	Oreochromis niloticus	33.98	1.00e-111	395.00
IUUC-Oan-072959	Ornithorhynchus anatinus	43.91	6.00e-46	175.00
IUUC-Ocu-074861	Oryctolagus cuniculus	36.95	7.00e-134	469.00
IUUC-Oba-075109	Oryza barthii	33.54	2.00e-108	385.00
IUUC-Obr-076292	Oryza brachyantha	35.18	2.00e-105	375.00
IUUC-Ogl-077065	Oryza glaberrima	34.79	3.00e-115	407.00
IUUC-Ogu-078776	Oryza glumaepatula	34.03	3.00e-112	397.00
IUUC-Oin-080048	Oryza indica	35.16	5.00e-113	400.00
IUUC-Olo-080711	Oryza longistaminata	33.72	2.00e-99	355.00
IUUC-Ome-081506	Oryza meridionalis	34.59	3.00e-102	364.00
IUUC-Oni-082320	Oryza nivara	32.74	2.00e-106	378.00
IUUC-Opu-083801	Oryza punctata	33.90	1.00e-103	369.00
IUUC-Oru-085139	Oryza rufipogon	32.74	2.00e-105	375.00
IUUC-Osa-085713	Oryza sativa	35.28	3.00e-116	410.00
IUUC-Ola-086951	Oryzias latipes	33.37	1.00e-107	382.00
IUUC-Olu-087822	Ostreococcus lucimarinus	31.37	2.00e-90	325.00
IUUC-Oga-088625	Otolemur garnettii	35.88	8.00e-130	456.00
IUUC-Oar-089995	Ovis aries	36.24	3.00e-130	457.00
IUUC-Ptr-090640	Pan troglodytes	37.03	4.00e-135	473.00
IUUC-Pan-091974	Papio anubis	36.18	2.00e-131	461.00
IUUC-Psi-093957	Pelodiscus sinensis	36.63	1.00e-134	472.00
IUUC-Pma-094242	Petromyzon marinus	38.50	1.00e-68	251.00
IUUC-Pno-094835	Phaeosphaeria nodorum	64.31	0.00e+00	890.00
IUUC-Ppa-095901	Physcomitrella patens	35.72	3.00e-125	441.00
IUUC-Pfo-097148	Poecilia formosa	34.38	3.00e-113	400.00
IUUC-Pab-098068	Pongo abelii	32.76	3.00e-105	374.00
IUUC-Pop-098943	Populus trichocarpa	34.56	1.00e-110	392.00
IUUC-Pca-100738	Procavia capensis	36.38	6.00e-89	320.00
IUUC-Ppe-101315	Prunus persica	34.43	2.00e-110	391.00
IUUC-Pva-102154	Pteropus vampyrus	36.35	2.00e-131	461.00
IUUC-Pgr-103343	Puccinia graminis	42.09	4.00e-144	503.00
IUUC-Ptt-103928	Puccinia triticina	36.04	1.00e-139	488.00
IUUC-Pte-104306	Pyrenophora teres	63.09	0.00e+00	919.00
IUUC-Pyt-104696	Pyrenophora triticirepentis	63.18	0.00e+00	937.00
IUUC-Rno-105801	Rattus norvegicus	36.42	2.00e-132	464.00
IUUC-Sce-106304	Saccharomyces cerevisiae	30.38	5.00e-100	357.00
IUUC-Sha-107635	Sarcophilus harrisii	36.71	3.00e-133	467.00
IUUC-Sja-107678	Schizosaccharomyces japonicus	41.53	2.00e-163	567.00
IUUC-Spo-108144	Schizosaccharomyces pombe	41.14	1.00e-164	571.00
IUUC-Smo-108848	Selaginella moellendorffii	37.03	3.00e-117	414.00
IUUC-Sit-110728	Setaria italica	34.51	8.00e-115	406.00
IUUC-Sly-111523	Solanum lycopersicum	35.77	2.00e-121	428.00
IUUC-Sar-113733	Sorex araneus	41.33	5.00e-58	217.00
IUUC-Sbi-114419	Sorghum bicolor	34.39	4.00e-111	394.00
IUUC-Sre-115225	Sporisorium reilianum	42.18	6.00e-179	619.00
IUUC-Ssc-115686	Sus scrofa	36.30	6.00e-131	459.00
IUUC-Tgu-117346	Taeniopygia guttata	35.90	4.00e-127	447.00
IUUC-Tru-118350	Takifugu rubripes	32.28	9.00e-110	389.00
IUUC-Tsy-119278	Tarsius syrichta	35.46	7.00e-91	326.00
IUUC-Tni-120658	Tetraodon nigroviridis	32.48	2.00e-104	371.00
IUUC-Tca-121585	Theobroma cacao	33.74	1.00e-109	389.00
IUUC-Tre-122043	Trichoderma reesei	56.66	0.00e+00	848.00
IUUC-Tvi-122303	Trichoderma virens	56.29	0.00e+00	850.00
IUUC-Tae-123798	Triticum aestivum	34.78	2.00e-112	398.00
IUUC-Tur-126732	Triticum urartu	32.35	5.00e-101	360.00
IUUC-Tme-126909	Tuber melanosporum	54.86	0.00e+00	818.00
IUUC-Tbe-127261	Tupaia belangeri	32.46	6.00e-69	254.00
IUUC-Ttr-128295	Tursiops truncatus	30.20	4.00e-89	321.00
IUUC-Uma-129599	Ustilago maydis	42.66	0.00e+00	630.00
IUUC-Vda-129688	Verticillium dahliae	55.81	0.00e+00	858.00
IUUC-Vpa-130170	Vicugna pacos	30.91	5.00e-77	280.00
IUUC-Vvi-131116	Vitis vinifera	34.47	2.00e-108	384.00
IUUC-Xtr-131953	Xenopus tropicalis	33.96	2.00e-117	415.00
IUUC-Xma-133837	Xiphophorus maculatus	34.25	9.00e-113	399.00
IUUC-Yli-134510	Yarrowia lipolytica	42.11	5.00e-169	586.00
IUUC-Zma-135786	Zea mays	34.15	5.00e-105	374.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence