iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Xtr-132073

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Ubiquitin-specific peptidase 7 (herpes virus-associated)

Genbank Nucleotide ID

AAMC01092777

Gene Name

usp7

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSXETG00000008697.3	ENSXETT00000019033.3	ENSXETP00000019033.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	9.80e-69	232.3	216	522

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgyeq 89
           +GlkN+g+tCYmNS+LQ+L+++++lr+++    + +      +++++++  +lq++f el ++++k v +++l+k++++e   +++++q
   Q: 216  VGLKNQGATCYMNSLLQTLFFTNQLRKAVYM-MPTEG-----DDSSKSVPLALQRVFYEL-QHSDKPVGTKKLTKSFGWET--LDSFMQ 295
           6******************************.44433.....466889************.88889************887..67**** PP
   S: 90   qDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpvpg 178
           +D+qE++++lld++e+++                          k +  + +i +lF+g++ s i+c++ d +s+r e+ +d++l+++g
   Q: 296  HDVQELCRVLLDNVENKM--------------------------KGTCVEGTIPKLFRGKMVSYIQCKHVDYRSERIEDYYDIQLSIKG 358
           ******************..........................789****************************************** PP
   S: 179  keetkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlspfcts 267
           k+     ++ +++ ++++ e+l+g+nky   +  ++qeaek +k+ ++P+vL+l+L+Rf ++ ++++++kin+++efp++L l++f+++
   Q: 359  KK-----NIFESFIDYVAVEQLDGDNKYDAGEH-GLQEAEKGVKFLTFPPVLHLQLMRFMYDPQTDQNIKINDRFEFPEQLPLDEFLQK 441
           **.....9*********************9996.7****************************************************** PP
   S: 268  peekqkekkkYeLiavvvHsGslssGHYvayvkn.ekgkWllfdDskVtevkeeevleetg............staYvlfYkr 337
           p++k+  + +Y L+av+vHsG  ++GHYv+y +   +gkW++fdD+ V+ +++ee  e +             ++aY+l+Y r
   Q: 442  PDSKD--PANYILHAVLVHSGDNHGGHYVVYLNPkGEGKWCKFDDDVVSRCTKEEAIEHNYgghdddlsvrhcTNAYMLVYIR 522
           **998..*************************9835666************86666664446*******************87 PP

Organism

Xenopus tropicalis

Protein Sequence
(Fasta)

LQHHAYGDYF WHAENTILDD PPSLDFQQSG DTDDPPRITP NPVINGNVAM ADGHNNTEED 60
MEDDTSWRSE ATFQFTVERF SRLSESVLSP PCFVRNLPWK IMVMPRFYPD RPHQKSVGFF 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTGCAGCACC ATGCGTATGG TGACTATTTT TGGCATGCCG AAAATACGTA CCATACGCTC 60
CTACCTGTGC CTGCACCCAA ATGAATGGAA TACGCTAGGG TGCAGACACA TGTAGCCGAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR002083--MATH/TRAF_dom
IPR001394--Peptidase_C19_UCH
IPR008974--TRAF-like
IPR024729--USP7_ICP0-binding_dom
IPR029346--USP_C
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS50144--MATH
PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00917--MATH
PF00443--UCH
PF14533--USP7_C2
PF12436--USP7_ICP0_bdg

SMART

SM00061--MATH

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000761	Aegilops tauschii	33.24	3.00e-137	483.00
IUUC-Aml-002408	Ailuropoda melanoleuca	92.32	0.00e+00	2053.00
IUUC-Atr-003067	Amborella trichopoda	37.30	1.00e-121	431.00
IUUC-Apl-003558	Anas platyrhynchos	92.97	0.00e+00	2086.00
IUUC-Aca-004518	Anolis carolinensis	87.17	0.00e+00	1945.00
IUUC-Aly-006453	Arabidopsis lyrata	36.03	4.00e-154	538.00
IUUC-Ath-007610	Arabidopsis thaliana	36.34	3.00e-150	525.00
IUUC-Ago-007849	Ashbya gossypii	31.51	1.00e-133	471.00
IUUC-Acl-008327	Aspergillus clavatus	34.54	1.00e-168	587.00
IUUC-Afl-008491	Aspergillus flavus	34.90	6.00e-162	565.00
IUUC-Afu-008804	Aspergillus fumigatus	35.56	2.00e-160	560.00
IUUC-Ang-009776	Aspergillus niger	34.88	8.00e-159	554.00
IUUC-Aor-009998	Aspergillus oryzae	34.16	1.00e-153	536.00
IUUC-Ate-010428	Aspergillus terreus	34.69	3.00e-160	559.00
IUUC-Ame-010903	Astyanax mexicanus	90.15	0.00e+00	2063.00
IUUC-Bgr-012132	Blumeria graminis	31.44	1.00e-143	504.00
IUUC-Bta-013192	Bos taurus	92.78	0.00e+00	2055.00
IUUC-Bci-013924	Botrytis cinerea	33.75	3.00e-145	509.00
IUUC-Bdi-015069	Brachypodium distachyon	37.56	3.00e-151	529.00
IUUC-Bol-016114	Brassica oleracea	36.80	3.00e-150	526.00
IUUC-Bra-017448	Brassica rapa	36.33	2.00e-150	526.00
IUUC-Cel-018219	Caenorhabditis elegans	33.63	1.00e-150	527.00
IUUC-Cja-019006	Callithrix jacchus	91.40	0.00e+00	2024.00
IUUC-Cfa-020361	Canis familiaris	92.51	0.00e+00	2055.00
IUUC-Cpo-022320	Cavia porcellus	92.14	0.00e+00	2048.00
IUUC-Cre-022708	Chlamydomonas reinhardtii	41.96	1.00e-91	330.00
IUUC-Csa-024050	Chlorocebus sabaeus	91.74	0.00e+00	2054.00
IUUC-Cho-024434	Choloepus hoffmanni	82.76	0.00e+00	1303.00
IUUC-Cin-025689	Ciona intestinalis	53.21	0.00e+00	1168.00
IUUC-Csv-025963	Ciona savignyi	52.07	0.00e+00	1120.00
IUUC-Cgl-026650	Colletotrichum gloeosporioides	33.12	2.00e-146	513.00
IUUC-Cne-026968	Cryptococcus neoformans	36.18	5.00e-177	615.00
IUUC-Cme-027103	Cyanidioschyzon merolae	35.81	2.00e-112	400.00
IUUC-Dre-028510	Danio rerio	89.14	0.00e+00	2061.00
IUUC-Dno-029696	Dasypus novemcinctus	92.04	0.00e+00	2042.00
IUUC-Dor-030611	Dipodomys ordii	76.16	0.00e+00	859.00
IUUC-Dse-031433	Dothistroma septosporum	33.93	2.00e-141	496.00
IUUC-Dme-031583	Drosophila melanogaster	48.29	0.00e+00	1009.00
IUUC-Ete-033191	Echinops telfairi	90.37	0.00e+00	2003.00
IUUC-Eca-034122	Equus caballus	92.13	0.00e+00	2045.00
IUUC-Eeu-035292	Erinaceus europaeus	81.64	0.00e+00	660.00
IUUC-Fca-036377	Felis catus	92.32	0.00e+00	2052.00
IUUC-Fal-036964	Ficedula albicollis	93.19	0.00e+00	2048.00
IUUC-Fox-037695	Fusarium oxysporum	33.42	4.00e-158	552.00
IUUC-Fso-038084	Fusarium solani	33.33	6.00e-157	548.00
IUUC-Gmo-038644	Gadus morhua	89.17	0.00e+00	2038.00
IUUC-Ggr-040029	Gaeumannomyces graminis	34.03	1.00e-155	543.00
IUUC-Gga-040944	Gallus gallus	93.28	0.00e+00	2078.00
IUUC-Gac-041740	Gasterosteus aculeatus	88.62	0.00e+00	2048.00
IUUC-Gma-043300	Glycine max	36.65	1.00e-165	577.00
IUUC-Ggo-044947	Gorilla gorilla	92.31	0.00e+00	2050.00
IUUC-Hsa-046278	Homo sapiens	91.56	0.00e+00	2049.00
IUUC-Hvu-047749	Hordeum vulgare	36.82	6.00e-135	474.00
IUUC-Itr-047904	Ictidomys tridecemlineatus	91.98	0.00e+00	1754.00
IUUC-Kpa-049121	Komagataella pastoris	31.00	9.00e-127	448.00
IUUC-Lch-049847	Latimeria chalumnae	93.03	0.00e+00	2106.00
IUUC-Lpe-051505	Leersia perrieri	35.47	7.00e-139	488.00
IUUC-Loc-052234	Lepisosteus oculatus	89.19	0.00e+00	1358.00
IUUC-Lma-053169	Leptosphaeria maculans	36.45	6.00e-164	572.00
IUUC-Laf-053566	Loxodonta africana	92.41	0.00e+00	2049.00
IUUC-Mcc-055549	Macaca mulatta	92.49	0.00e+00	2046.00
IUUC-Meu-056887	Macropus eugenii	82.08	0.00e+00	1169.00
IUUC-Mor-057149	Magnaporthe oryzae	35.23	8.00e-160	558.00
IUUC-Mpo-057536	Magnaporthe poae	33.79	1.00e-156	547.00
IUUC-Mtr-058583	Medicago truncatula	37.91	9.00e-158	551.00
IUUC-Mla-058899	Melampsora laricipopulina	37.51	2.00e-169	589.00
IUUC-Mga-060148	Meleagris gallopavo	93.14	0.00e+00	2090.00
IUUC-Mvi-060207	Microbotryum violaceum	36.23	9.00e-179	620.00
IUUC-Mmr-060946	Microcebus murinus	91.74	0.00e+00	2053.00
IUUC-Mdo-062079	Monodelphis domestica	85.79	0.00e+00	1846.00
IUUC-Mmu-063678	Mus musculus	92.04	0.00e+00	2042.00
IUUC-Mac-065416	Musa acuminata	36.66	2.00e-152	533.00
IUUC-Mpu-066744	Mustela putorius furo	92.44	0.00e+00	2009.00
IUUC-Mlu-067949	Myotis lucifugus	91.67	0.00e+00	2028.00
IUUC-Nfi-068342	Neosartorya fischeri	35.41	1.00e-160	560.00
IUUC-Ncr-068818	Neurospora crassa	33.91	8.00e-162	564.00
IUUC-Nle-070064	Nomascus leucogenys	91.65	0.00e+00	2051.00
IUUC-Opr-071001	Ochotona princeps	90.83	0.00e+00	1687.00
IUUC-Ont-072095	Oreochromis niloticus	89.43	0.00e+00	2046.00
IUUC-Oan-073483	Ornithorhynchus anatinus	93.19	0.00e+00	2016.00
IUUC-Ocu-073967	Oryctolagus cuniculus	91.99	0.00e+00	1978.00
IUUC-Oba-075811	Oryza barthii	34.27	1.00e-136	481.00
IUUC-Obr-076514	Oryza brachyantha	36.38	2.00e-151	530.00
IUUC-Ogl-077038	Oryza glaberrima	35.54	4.00e-145	509.00
IUUC-Ogu-078265	Oryza glumaepatula	34.04	3.00e-131	463.00
IUUC-Oin-079513	Oryza indica	35.34	4.00e-138	485.00
IUUC-Olo-081067	Oryza longistaminata	34.22	4.00e-135	475.00
IUUC-Ome-081879	Oryza meridionalis	35.98	1.00e-146	513.00
IUUC-Oni-082461	Oryza nivara	34.64	4.00e-142	499.00
IUUC-Opu-083199	Oryza punctata	35.64	3.00e-143	502.00
IUUC-Oru-085109	Oryza rufipogon	35.45	7.00e-142	498.00
IUUC-Osa-085418	Oryza sativa	36.66	1.00e-126	447.00
IUUC-Ola-086640	Oryzias latipes	89.45	0.00e+00	2038.00
IUUC-Olu-087874	Ostreococcus lucimarinus	33.27	2.00e-139	490.00
IUUC-Oga-089059	Otolemur garnettii	85.32	0.00e+00	1857.00
IUUC-Oar-089710	Ovis aries	92.87	0.00e+00	2056.00
IUUC-Ptr-091334	Pan troglodytes	92.31	0.00e+00	2050.00
IUUC-Pan-091717	Papio anubis	92.65	0.00e+00	1988.00
IUUC-Psi-093933	Pelodiscus sinensis	91.69	0.00e+00	2083.00
IUUC-Pma-094648	Petromyzon marinus	80.00	0.00e+00	1656.00
IUUC-Pno-095020	Phaeosphaeria nodorum	35.89	1.00e-149	523.00
IUUC-Ppa-096020	Physcomitrella patens	34.87	4.00e-160	558.00
IUUC-Pfo-096181	Poecilia formosa	88.24	0.00e+00	2047.00
IUUC-Pab-098231	Pongo abelii	89.81	0.00e+00	1978.00
IUUC-Pop-099680	Populus trichocarpa	36.67	5.00e-155	541.00
IUUC-Pca-100543	Procavia capensis	73.60	0.00e+00	895.00
IUUC-Ppe-101847	Prunus persica	36.85	2.00e-149	523.00
IUUC-Pva-102472	Pteropus vampyrus	91.12	0.00e+00	2009.00
IUUC-Pgr-103463	Puccinia graminis	36.93	5.00e-168	585.00
IUUC-Ptt-103716	Puccinia triticina	37.89	2.00e-164	573.00
IUUC-Pte-104360	Pyrenophora teres	35.88	2.00e-145	510.00
IUUC-Pyt-104581	Pyrenophora triticirepentis	35.33	2.00e-144	506.00
IUUC-Rno-105816	Rattus norvegicus	91.47	0.00e+00	2048.00
IUUC-Sce-106230	Saccharomyces cerevisiae	38.95	1.00e-111	398.00
IUUC-Sha-107439	Sarcophilus harrisii	93.32	0.00e+00	2057.00
IUUC-Sja-107690	Schizosaccharomyces japonicus	32.32	1.00e-134	474.00
IUUC-Spo-108019	Schizosaccharomyces pombe	33.93	2.00e-138	486.00
IUUC-Smo-109308	Selaginella moellendorffii	35.67	1.00e-147	517.00
IUUC-Sit-110367	Setaria italica	36.00	3.00e-152	532.00
IUUC-Sly-111337	Solanum lycopersicum	37.14	2.00e-157	549.00
IUUC-Stu-112387	Solanum tuberosum	36.25	2.00e-159	556.00
IUUC-Sar-113685	Sorex araneus	91.30	0.00e+00	2026.00
IUUC-Sbi-114037	Sorghum bicolor	36.70	4.00e-152	532.00
IUUC-Sre-115156	Sporisorium reilianum	38.05	1.00e-178	620.00
IUUC-Ssc-116297	Sus scrofa	91.74	0.00e+00	2054.00
IUUC-Tgu-116767	Taeniopygia guttata	92.22	0.00e+00	2088.00
IUUC-Tru-118208	Takifugu rubripes	89.17	0.00e+00	2013.00
IUUC-Tsy-119277	Tarsius syrichta	86.68	0.00e+00	692.00
IUUC-Tni-119890	Tetraodon nigroviridis	88.99	0.00e+00	2009.00
IUUC-Tca-121501	Theobroma cacao	35.97	4.00e-153	535.00
IUUC-Tre-122169	Trichoderma reesei	33.39	5.00e-149	522.00
IUUC-Tvi-122600	Trichoderma virens	34.30	8.00e-158	551.00
IUUC-Tae-125264	Triticum aestivum	34.92	6.00e-151	528.00
IUUC-Tur-126287	Triticum urartu	34.89	2.00e-143	503.00
IUUC-Tme-127045	Tuber melanosporum	34.32	3.00e-163	569.00
IUUC-Tbe-127696	Tupaia belangeri	84.36	8.00e-153	534.00
IUUC-Ttr-129161	Tursiops truncatus	92.50	0.00e+00	2047.00
IUUC-Uma-129535	Ustilago maydis	37.21	0.00e+00	637.00
IUUC-Vda-129708	Verticillium dahliae	33.03	2.00e-154	540.00
IUUC-Vvi-130882	Vitis vinifera	37.07	4.00e-150	525.00
IUUC-Xma-133949	Xiphophorus maculatus	88.13	0.00e+00	2038.00
IUUC-Yli-134527	Yarrowia lipolytica	31.40	5.00e-133	469.00
IUUC-Zma-135855	Zea mays	36.33	5.00e-143	502.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence