iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Laf-053358

Ensembl Protein ID

ENSLAFP00000023641.1

UniProt Accession

G3U733; G3U733_LOXAF

Protein Name

Uncharacterized protein

Gene Name

HIC1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLAFG00000001259.2	ENSLAFT00000001259.2	ENSLAFP00000023641.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_Other: BTB	1.00e-12	48.6	37	97

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_Other: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveik.d.vqpevfrallkFlYtgkld 66
           +Dvi+vv++  f+ahk vLaasS ++++l  +        +  +++ d v+p vfr +l+F+Ytg+l+
   Q: 37   CDVIIVVQNALFRAHKNVLAASSAYLKSLVVH-------DNLLNLDhDmVSPAVFRLVLDFIYTGRLT 97
           9*****************************77.......4566677678*****************96 PP

Organism

Loxodonta africana

Protein Sequence
(Fasta)

PAGDCAGQTM LDTMEAPGHS RQLLLQLNNQ RTKGFLCDVI IVVQNALFRA HKNVLAASSA 60
YLKSLVVHDN LLNLDHDMVS PAVFRLVLDF IYTGRLTDGA EAAAAAAVAP GTEPSLGAVL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCTGCAGGAG ATTGTGCTGG GCAGACGATG CTGGACACGA TGGAGGCGCC GGGCCACTCG 60
AGGCAGCTGC TACTGCAGCT CAACAACCAG CGCACCAAGG GCTTCTTGTG CGACGTGATC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR000210--BTB/POZ_dom
IPR023413--GFP-like
IPR028424--HIC1
IPR011333--SKP1/BTB/POZ
IPR013087--Znf_C2H2_type

PROSITE

PS50097--BTB
PS00028--ZINC_FINGER_C2H2_1
PS50157--ZINC_FINGER_C2H2_2

Pfam

PF00651--BTB

SMART

SM00225--BTB
SM00355--ZnF_C2H2

Gene Ontology

GO:0005829--C:cytosol
GO:0005654--C:nucleoplasm
GO:0046872--F:metal ion binding
GO:0043565--F:sequence-specific DNA binding
GO:0003700--F:transcription factor activity, sequence-specific DNA binding
GO:0008630--P:intrinsic apoptotic signaling pathway in response to DNA damage
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0030178--P:negative regulation of Wnt signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001347	Ailuropoda melanoleuca	92.12	4.00e-150	525.00
IUUC-Apl-004217	Anas platyrhynchos	67.20	3.00e-70	259.00
IUUC-Aca-004680	Anolis carolinensis	58.23	3.00e-63	236.00
IUUC-Ame-010967	Astyanax mexicanus	61.47	5.00e-95	342.00
IUUC-Bta-013567	Bos taurus	85.67	0.00e+00	745.00
IUUC-Cja-019621	Callithrix jacchus	95.96	6.00e-48	182.00
IUUC-Cfa-020731	Canis familiaris	97.54	1.00e-163	570.00
IUUC-Cpo-021326	Cavia porcellus	94.10	2.00e-162	566.00
IUUC-Csa-023645	Chlorocebus sabaeus	98.53	1.00e-162	566.00
IUUC-Dre-028027	Danio rerio	58.09	4.00e-91	328.00
IUUC-Dno-028900	Dasypus novemcinctus	96.56	3.00e-158	551.00
IUUC-Dor-030484	Dipodomys ordii	62.60	3.00e-43	168.00
IUUC-Ete-033019	Echinops telfairi	63.25	2.00e-38	153.00
IUUC-Eca-033737	Equus caballus	68.82	1.00e-68	254.00
IUUC-Eeu-035190	Erinaceus europaeus	58.54	5.00e-45	175.00
IUUC-Fca-036031	Felis catus	68.82	1.00e-68	253.00
IUUC-Fal-036980	Ficedula albicollis	61.18	3.00e-109	389.00
IUUC-Gmo-039209	Gadus morhua	69.52	5.00e-68	252.00
IUUC-Gga-040708	Gallus gallus	70.29	3.00e-106	379.00
IUUC-Gac-041742	Gasterosteus aculeatus	73.82	1.00e-77	284.00
IUUC-Ggo-044591	Gorilla gorilla	99.41	1.00e-139	490.00
IUUC-Hsa-046769	Homo sapiens	98.53	1.00e-158	553.00
IUUC-Itr-048627	Ictidomys tridecemlineatus	95.24	3.00e-168	585.00
IUUC-Lch-049412	Latimeria chalumnae	64.09	3.00e-104	372.00
IUUC-Loc-051883	Lepisosteus oculatus	63.06	4.00e-92	332.00
IUUC-Mcc-054981	Macaca mulatta	98.53	1.00e-162	566.00
IUUC-Meu-056181	Macropus eugenii	89.33	2.00e-71	263.00
IUUC-Mga-059592	Meleagris gallopavo	73.20	3.00e-103	368.00
IUUC-Mmr-061560	Microcebus murinus	93.65	5.00e-160	557.00
IUUC-Mdo-062511	Monodelphis domestica	81.45	1.00e-90	327.00
IUUC-Mmu-064258	Mus musculus	93.44	3.00e-159	555.00
IUUC-Mpu-065911	Mustela putorius furo	97.54	1.00e-163	569.00
IUUC-Mlu-067575	Myotis lucifugus	76.18	2.00e-115	409.00
IUUC-Nle-069726	Nomascus leucogenys	86.24	1.00e-59	224.00
IUUC-Opr-071056	Ochotona princeps	63.36	8.00e-44	171.00
IUUC-Ont-072493	Oreochromis niloticus	65.69	2.00e-80	293.00
IUUC-Ocu-073887	Oryctolagus cuniculus	69.23	5.00e-68	252.00
IUUC-Ola-086584	Oryzias latipes	62.42	3.00e-90	326.00
IUUC-Oga-088774	Otolemur garnettii	92.39	4.00e-163	568.00
IUUC-Ptr-090491	Pan troglodytes	95.90	4.00e-125	441.00
IUUC-Pan-092901	Papio anubis	68.82	1.00e-68	254.00
IUUC-Psi-093290	Pelodiscus sinensis	63.55	4.00e-70	258.00
IUUC-Pma-094179	Petromyzon marinus	70.51	4.00e-31	125.00
IUUC-Pfo-096282	Poecilia formosa	59.52	2.00e-88	320.00
IUUC-Pab-098488	Pongo abelii	88.31	0.00e+00	778.00
IUUC-Pca-100667	Procavia capensis	94.92	1.00e-142	500.00
IUUC-Pva-102421	Pteropus vampyrus	97.05	3.00e-163	568.00
IUUC-Rno-105528	Rattus norvegicus	94.32	2.00e-151	529.00
IUUC-Sar-113478	Sorex araneus	98.76	5.00e-119	421.00
IUUC-Ssc-115420	Sus scrofa	90.27	6.00e-166	577.00
IUUC-Tgu-116642	Taeniopygia guttata	71.25	3.00e-107	382.00
IUUC-Tru-118583	Takifugu rubripes	62.34	5.00e-85	308.00
IUUC-Tni-119907	Tetraodon nigroviridis	61.83	4.00e-58	218.00
IUUC-Xtr-132210	Xenopus tropicalis	62.07	7.00e-112	397.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence