iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Kpa-049299

Ensembl Protein ID

CAY68695

UniProt Accession

C4QZM1; C4QZM1_KOMPG

Genbank Protein ID

CAY68695.1

Protein Name

Protein required for mismatch repair in mitosis and meiosis, forms a complex with Msh2p to repair bo

Genbank Nucleotide ID

FN392320

Gene Name

PAS_chr2-1_0094

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
PAS_chr2-1_0094	CAY68695	CAY68695

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
ULD/UDP/UFD/PB1	38.71	3.90e+00	26.60	IUUC-Ots-000022

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Komagataella pastoris

Functional Description
(View)

Component of the post-replicative DNA mismatch repair system (MMR).

Protein Sequence
(Fasta)

MAKKKVVAPD NQPSVFSFFK KKPSVNSAEP KKEQKLPTPS SSPQKADLSS GTSDKENHPT 60
TPTKNEHKTQ LPSASSSVVR ANKLEDDEEE GVVSGRKRRR VAIDSEDEED AFDEEESVDN 120

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Nucleotide Sequence
(Fasta)

ATGGCCAAGA AGAAAGTCGT TGCTCCGGAC AATCAGCCTT CCGTGTTTTC TTTCTTCAAG 60
AAGAAGCCAA GTGTGAATTC AGCTGAACCT AAGAAGGAGC AGAAACTACC TACCCCTTCA 120

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Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0227--DNA damage
KW-0234--DNA repair
KW-0238--DNA-binding
KW-0547--Nucleotide-binding
KW-1185--Reference proteome

Interpro

IPR007695--DNA_mismatch_repair_MutS-lik_N
IPR000432--DNA_mismatch_repair_MutS_C
IPR007861--DNA_mismatch_repair_MutS_clamp
IPR007696--DNA_mismatch_repair_MutS_core
IPR016151--DNA_mismatch_repair_MutS_N
IPR007860--DNA_mmatch_repair_MutS_con_dom
IPR027417--P-loop_NTPase

PROSITE

PS00486--DNA_MISMATCH_REPAIR_2

Pfam

PF01624--MutS_I
PF05188--MutS_II
PF05192--MutS_III
PF05190--MutS_IV
PF00488--MutS_V

SMART

SM00534--MUTSac
SM00533--MUTSd

Gene Ontology

GO:0005829--C:cytosol
GO:0005634--C:nucleus
GO:0005524--F:ATP binding
GO:0030983--F:mismatched DNA binding
GO:0043570--P:maintenance of DNA repeat elements
GO:0006298--P:mismatch repair

KEGG

ppa:PAS_chr2-1_0094

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Cho-024874	Choloepus hoffmanni	35.71	4.10e-01	26.60
IUUC-Cin-025349	Ciona intestinalis	27.54	5.20e-01	26.60
IUUC-Cgl-026754	Colletotrichum gloeosporioides	22.76	8.20e-01	27.30
IUUC-Lma-052954	Leptosphaeria maculans	44.12	1.30e-01	30.00
IUUC-Mpo-057412	Magnaporthe poae	26.51	2.80e-01	28.90
IUUC-Mla-059046	Melampsora laricipopulina	26.53	9.80e-02	28.10
IUUC-Pma-094753	Petromyzon marinus	44.83	1.70e+00	25.40

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence