iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ont-071447

Ensembl Protein ID

ENSONIP00000011240.1

UniProt Accession

I3JQU6; I3JQU6_ORENI

Genbank Protein ID

ENSONIP00000011240

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AERX01017586

Gene Name

WDSUB1 (1 of many)

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSONIG00000008943.1	ENSONIT00000011249.1	ENSONIP00000011240.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	5.30e-34	115.2	52	88
E3 activity/RING/U-box	1.30e-25	89.7	407	477
UBD/Beta-Prp	5.50e-51	173.9	142	338

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvl 35
           gH  +v+c++f s+  +l+s+s Dg++ vW+  tg +
   Q: 52   GHGYGVHCCCFsSCgSFLLSCSTDGSVIVWSAETGEV 88
           8999*******966799**************888865 PP

E3 activity/RING/U-box

   S: 2    vpeeflCpIslelMrdPvvlpsGitydrssIekwlasggktcPvtrqplteedlvPnltlrrliqawceen 72
            p+eflCpI+ elM+dPv++++G++y+r+sIe w++ ++kt+P+t+ pl+ + l+Pn +l+  i +w + +
   Q: 407  APDEFLCPITRELMKDPVIAADGYSYERESIESWIRGKNKTSPMTNLPLQTTLLTPNRSLKMAITRWKSNQ 477
           79*****************************************************************8765 PP

UBD/Beta-Prp

   S: 12   vitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgk........ilvtgseDrtikvwdls.......... 82
           v+ + +fsp  ++++tg+++g +k+wd++t  l ++   h+ +vt+++f p+           l+++++D  +k+w +s          
   Q: 142  VV-ACCFSPCAQMFVTGCTRGDLKLWDAHTSLLHAEKDAHDLGVTCCCFAPQFIingccvefRLASCGQDSQLKIWIVSqregadillk 229
           33.3699***********************88888889*************988888999999*************5554555555565 PP
   S: 83   tgkcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdl..... 166
            ++   tl+ +++ vls++fs +g+++vsGs d+ + v+d + g++l+ tl++hd+ v+ v+++p+   +++Gs Dr v++W++     
   Q: 230  YSSSRGTLTSQTAPVLSCAFSSDGEWVVSGSVDKSVAVYDASLGTVLQ-TLKQHDRYVTAVALSPTFPWIATGSMDRSVNVWRIgaaes 317
           66677778899*************************************.****************99*****************77777 PP
   S: 167  ............ktgkllrtl 175
                        +g ll+++
   Q: 318  ketrcqgrklpgHSGLLLTDW 338
           666666666655555555555 PP

Organism

Oreochromis niloticus

Protein Sequence
(Fasta)

MVSLICTLRH HTDEVTCCAF SPSLLATSSG DKTLRVYTTA NFSELPFSPL RGHGYGVHCC 60
CFSSCGSFLL SCSTDGSVIV WSAETGEVKE TLEHPGRSPL RVCALAPDSS LLLAGACDGT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGTGTCTT TAATTTGCAC TCTCCGACAT CATACAGATG AGGTCACCTG CTGTGCCTTC 60
TCTCCATCCC TCCTGGCGAC CTCCTCCGGT GATAAAACGC TCCGTGTTTA TACCACGGCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR001660--SAM
IPR013761--SAM/pointed
IPR003613--Ubox_domain
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50105--SAM_DOMAIN
PS51698--U_BOX
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00536--SAM_1
PF04564--U-box
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00454--SAM
SM00504--Ubox
SM00320--WD40

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Cin-025786	Ciona intestinalis	36.95	5.00e-81	295.00
IUUC-Ete-032405	Echinops telfairi	54.20	6.00e-100	357.00
IUUC-Gac-042617	Gasterosteus aculeatus	77.20	0.00e+00	712.00
IUUC-Pma-094383	Petromyzon marinus	43.55	2.00e-114	406.00
IUUC-Pfo-096832	Poecilia formosa	78.56	0.00e+00	737.00
IUUC-Tru-117674	Takifugu rubripes	75.00	0.00e+00	746.00
IUUC-Tni-119804	Tetraodon nigroviridis	73.63	0.00e+00	682.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence