iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Pfo-096832

Ensembl Protein ID

ENSPFOP00000017667.2

UniProt Accession

A0A087YI14; A0A087YI14_POEFO

Genbank Protein ID

ENSPFOP00000017667

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AYCK01002230

Gene Name

WDSUB1 (1 of many)

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPFOG00000017559.2	ENSPFOT00000017689.2	ENSPFOP00000017667.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	4.70e-32	109.2	11	43
E3 activity/RING/U-box	1.90e-25	89.3	410	479
UBD/Beta-Prp	5.30e-52	177.4	140	317

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    HtdsvtclafsdtllvsGsdDgtikvWDlrtgv 34
           Htd+++c+afs   lv+Gs D+t++v+++ +++
   Q: 11   HTDEISCCAFSQSALVTGSADKTLRVYSTADFK 43
           **********4369*************987765 PP

E3 activity/RING/U-box

   S: 2    vpeeflCpIslelMrdPvvlpsGitydrssIekwlasggktcPvtrqplteedlvPnltlrrliqawcee 71
            p+eflCpI+ elM+dPv++++G++y+r+sIe w++ ++kt+P+t+ pl+ + l+Pn +l+  i +w ++
   Q: 410  APDEFLCPITRELMKDPVIAADGYSYERESIESWIRGKNKTSPMTNLPLRTTLLTPNRSLKMAITRWKSS 479
           79*****************************************************************875 PP

UBD/Beta-Prp

   S: 11   svitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgk........ilvtgseDrtikvwdls.......tg 84
           + i +  fsp +++++tg++ g +k+wd +   ll++   h+ +vt+++f p+ k         l+++++D ++k+w +s       t 
   Q: 140  ASIVACSFSPCSQVFVTGCTHGDLKLWDDHISILLAKKDAHDLGVTCCSFAPHFKiedscvelRLASCGQDSLLKIWIVSqregtawTM 228
           45556789***********************************************999****99*************7777788888** PP
   S: 85   kcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdl....... 166
             +h+l+g+++ vls++fs++g+ +vsGs d+ + v+d + g+ l+ +l++hd+ v+ v+++p   l+++Gs Dr v++W++       
   Q: 229  MLLHILTGQTAPVLSCAFSADGELVVSGSVDKSVTVYDANLGTLLH-VLKQHDRYVTAVALSPAFGLMATGSMDRSVNVWKIgdgyeet 316
           **********************************************.****************88***************994444444 PP
   S: 167  k 167
           +
   Q: 317  A 317
           0 PP

Organism

Poecilia formosa

Protein Sequence
(Fasta)

MVSLIRAIRD HTDEISCCAF SQSALVTGSA DKTLRVYSTA DFKELPFSPL TGHGYGVHRC 60
CFSSCGSYLL SCSTDGSIIV WSSETGELLS AVEHPGRSPL RVCALAPDSC LLLAGACDGT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGAGAAATTT TATTGGTGTG CTGTAGGCGG AAGCAAGGAA ATACTTATTA ACGAGCAAGG 60
GCCTCATTTC ACTTTCTGGA CATTTGTCAG TTTTCAAACA GCGACAGAAC AGCAGGCAGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR001660--SAM
IPR013761--SAM/pointed
IPR003613--Ubox_domain
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50105--SAM_DOMAIN
PS51698--U_BOX
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF07647--SAM_2
PF04564--U-box
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00454--SAM
SM00504--Ubox
SM00320--WD40

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aca-004257	Anolis carolinensis	49.19	3.00e-137	482.00
IUUC-Bta-013032	Bos taurus	51.76	9.00e-146	509.00
IUUC-Cja-018743	Callithrix jacchus	53.01	3.00e-146	511.00
IUUC-Cho-025083	Choloepus hoffmanni	40.68	2.00e-78	286.00
IUUC-Cin-025786	Ciona intestinalis	36.44	2.00e-81	296.00
IUUC-Ete-032405	Echinops telfairi	52.87	1.00e-100	359.00
IUUC-Fal-036976	Ficedula albicollis	41.43	2.00e-102	366.00
IUUC-Gga-040561	Gallus gallus	49.18	4.00e-140	491.00
IUUC-Gac-042617	Gasterosteus aculeatus	71.93	0.00e+00	686.00
IUUC-Meu-055962	Macropus eugenii	44.70	1.00e-110	393.00
IUUC-Ont-071447	Oreochromis niloticus	78.56	0.00e+00	706.00
IUUC-Oga-088388	Otolemur garnettii	53.43	3.00e-147	515.00
IUUC-Oar-089748	Ovis aries	52.38	6.00e-146	510.00
IUUC-Pan-091769	Papio anubis	52.44	2.00e-98	352.00
IUUC-Pma-094383	Petromyzon marinus	41.54	1.00e-108	386.00
IUUC-Pab-098139	Pongo abelii	51.52	1.00e-111	396.00
IUUC-Pva-102286	Pteropus vampyrus	52.39	9.00e-141	493.00
IUUC-Tru-117674	Takifugu rubripes	69.90	0.00e+00	706.00
IUUC-Tni-119804	Tetraodon nigroviridis	68.97	0.00e+00	659.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence