iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ame-010922

Ensembl Protein ID

ENSAMXP00000006074.1

UniProt Accession

W5KER3; W5KER3_ASTMX

Genbank Protein ID

ENSAMXP00000006074

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

APWO01002771

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAMXG00000005818.1	ENSAMXT00000006074.1	ENSAMXP00000006074.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	6.50e-25	86.4	182	214
UBD/Beta-Prp	5.90e-51	173.7	12	250

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf...sd.tllvsGsdDgtikvWD 29
           gH+ +v+c+++    d ++l+sG+dD  +k+WD
   Q: 182  GHEKGVNCIDYysgGDkPYLISGADDRLVKIWD 214
           8*********9999778**************** PP

UBD/Beta-Prp

   S: 8    hhksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkgheds 96
           ++++++++v+ +p +++++++ ++g++ vw+ +t++l+++++ ++ +v+a kf  ++++ +tg++D+ i+v++++t + vh +++h+d+
   Q: 12   ARSDRVKSVDLHPTEPWMLASLYNGSVCVWNHETQTLVKTFEVCDLPVRASKFVARKNWVITGADDMQIRVFNYNTLERVHMFEAHSDY 100
           67899************************************************************************************ PP
   S: 97   vlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdg.nllvsGslDrtvrlWdlktgkllrtltgghtdsvy 184
           +++++++p++ ++++ s+d  i++wd+e+++  +++++gh++ v+ +v++p++ n ++s+slDrt+++W+l + +   tl+g h++ v+
   Q: 101  IRCIAVHPTQPYILTSSDDMLIKLWDWEKKWSCSQVFEGHTHYVMQIVINPKDnNQFASASLDRTIKVWQLGSSSPNFTLEG-HEKGVN 188
           *******************************9999**********************************************9.****** PP
   S: 185  slsfdsng..kelvsgsldgtvklwdlqtgec......vrtlnghtdnvksvrfspnderlv 238
           ++++ s g  ++l+sg++d+ vk+wd+q   +       +t+ +  + ++++  s+ + +l+
   Q: 189  CIDYYSGGdkPYLISGADDRLVKIWDYQVWIVffffffYNTYVERATMTCCLSSSEPNSHLY 250
           ***8887777*****************95444444444556666666666666665555554 PP

Organism

Astyanax mexicanus

Protein Sequence
(Fasta)

PLRLDIKRKL TARSDRVKSV DLHPTEPWML ASLYNGSVCV WNHETQTLVK TFEVCDLPVR 60
ASKFVARKNW VITGADDMQI RVFNYNTLER VHMFEAHSDY IRCIAVHPTQ PYILTSSDDM 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCTCTGAGGC TGGACATCAA GCGCAAGCTC ACGGCTCGGT CCGACCGTGT CAAGAGCGTG 60
GACCTTCATC CCACGGAGCC ATGGATGCTG GCCAGTCTGT ACAACGGCAG CGTCTGCGTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0853--WD repeat

Interpro

IPR006692--Coatomer_WD-assoc_reg
IPR020472--G-protein_beta_WD-40_rep
IPR011044--Quino_amine_DH_bsu
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF04053--Coatomer_WDAD
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0016021--C:integral component of membrane
GO:0030117--C:membrane coat
GO:0005198--F:structural molecule activity
GO:0006886--P:intracellular protein transport
GO:0030903--P:notochord development
GO:0061053--P:somite development
GO:0016192--P:vesicle-mediated transport

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000654	Aegilops tauschii	50.82	0.00e+00	885.00
IUUC-Aml-002154	Ailuropoda melanoleuca	68.64	0.00e+00	1164.00
IUUC-Atr-003090	Amborella trichopoda	43.25	0.00e+00	656.00
IUUC-Apl-003976	Anas platyrhynchos	68.97	0.00e+00	1186.00
IUUC-Aca-004301	Anolis carolinensis	68.56	0.00e+00	1170.00
IUUC-Aly-006508	Arabidopsis lyrata	43.74	0.00e+00	667.00
IUUC-Ath-007635	Arabidopsis thaliana	43.74	0.00e+00	667.00
IUUC-Ago-007914	Ashbya gossypii	39.31	7.00e-169	587.00
IUUC-Acl-008237	Aspergillus clavatus	48.41	0.00e+00	788.00
IUUC-Afl-008535	Aspergillus flavus	47.31	0.00e+00	732.00
IUUC-Afu-008845	Aspergillus fumigatus	46.17	0.00e+00	761.00
IUUC-Ani-009135	Aspergillus nidulans	47.60	0.00e+00	734.00
IUUC-Ang-009654	Aspergillus niger	46.43	0.00e+00	677.00
IUUC-Aor-009939	Aspergillus oryzae	47.21	0.00e+00	788.00
IUUC-Ate-010355	Aspergillus terreus	47.03	0.00e+00	737.00
IUUC-Bgr-012249	Blumeria graminis	45.79	0.00e+00	734.00
IUUC-Bta-013579	Bos taurus	70.31	0.00e+00	1006.00
IUUC-Bci-013866	Botrytis cinerea	47.37	0.00e+00	737.00
IUUC-Bdi-015046	Brachypodium distachyon	56.37	0.00e+00	956.00
IUUC-Bol-015731	Brassica oleracea	55.78	0.00e+00	970.00
IUUC-Bra-017758	Brassica rapa	56.02	0.00e+00	969.00
IUUC-Cel-018387	Caenorhabditis elegans	47.57	0.00e+00	791.00
IUUC-Cja-019145	Callithrix jacchus	67.71	0.00e+00	1166.00
IUUC-Cfa-020564	Canis familiaris	67.71	0.00e+00	1165.00
IUUC-Cpo-022201	Cavia porcellus	67.60	0.00e+00	1165.00
IUUC-Cre-022938	Chlamydomonas reinhardtii	54.55	0.00e+00	859.00
IUUC-Csa-023383	Chlorocebus sabaeus	72.07	0.00e+00	867.00
IUUC-Cho-024454	Choloepus hoffmanni	65.62	0.00e+00	965.00
IUUC-Cin-025681	Ciona intestinalis	65.75	0.00e+00	1119.00
IUUC-Csv-026012	Ciona savignyi	64.06	0.00e+00	1095.00
IUUC-Cgl-026649	Colletotrichum gloeosporioides	48.36	0.00e+00	719.00
IUUC-Cne-026986	Cryptococcus neoformans	46.14	0.00e+00	776.00
IUUC-Cme-027219	Cyanidioschyzon merolae	34.99	2.00e-152	533.00
IUUC-Dre-027846	Danio rerio	70.99	0.00e+00	1233.00
IUUC-Dor-030462	Dipodomys ordii	78.16	0.00e+00	1092.00
IUUC-Dse-031268	Dothistroma septosporum	46.91	0.00e+00	764.00
IUUC-Dme-031791	Drosophila melanogaster	65.12	0.00e+00	1100.00
IUUC-Ete-033166	Echinops telfairi	72.89	0.00e+00	806.00
IUUC-Eca-034180	Equus caballus	67.88	0.00e+00	1179.00
IUUC-Eeu-035086	Erinaceus europaeus	80.72	0.00e+00	797.00
IUUC-Fca-036265	Felis catus	67.71	0.00e+00	1167.00
IUUC-Fal-037202	Ficedula albicollis	69.41	0.00e+00	1200.00
IUUC-Fox-037711	Fusarium oxysporum	47.91	0.00e+00	706.00
IUUC-Fso-038268	Fusarium solani	47.62	0.00e+00	706.00
IUUC-Gmo-039046	Gadus morhua	70.55	0.00e+00	1207.00
IUUC-Ggr-039863	Gaeumannomyces graminis	46.78	0.00e+00	725.00
IUUC-Gga-041112	Gallus gallus	68.97	0.00e+00	1186.00
IUUC-Gac-041733	Gasterosteus aculeatus	80.02	0.00e+00	1403.00
IUUC-Gma-042910	Glycine max	45.75	0.00e+00	710.00
IUUC-Ggo-044984	Gorilla gorilla	67.49	0.00e+00	1161.00
IUUC-Hsa-046698	Homo sapiens	67.37	0.00e+00	1161.00
IUUC-Hvu-047669	Hordeum vulgare	55.65	2.00e-123	435.00
IUUC-Itr-048212	Ictidomys tridecemlineatus	68.99	0.00e+00	1167.00
IUUC-Kpa-049265	Komagataella pastoris	42.16	0.00e+00	687.00
IUUC-Lch-050473	Latimeria chalumnae	74.31	0.00e+00	1423.00
IUUC-Lpe-051579	Leersia perrieri	56.36	0.00e+00	946.00
IUUC-Loc-052675	Lepisosteus oculatus	70.00	0.00e+00	1205.00
IUUC-Lma-053218	Leptosphaeria maculans	45.47	0.00e+00	723.00
IUUC-Laf-053757	Loxodonta africana	67.78	0.00e+00	1163.00
IUUC-Mcc-054859	Macaca mulatta	67.71	0.00e+00	1165.00
IUUC-Meu-056174	Macropus eugenii	90.29	0.00e+00	711.00
IUUC-Mor-057264	Magnaporthe oryzae	47.26	0.00e+00	710.00
IUUC-Mpo-057538	Magnaporthe poae	47.02	0.00e+00	738.00
IUUC-Mtr-058310	Medicago truncatula	45.63	0.00e+00	716.00
IUUC-Mla-058937	Melampsora laricipopulina	44.43	0.00e+00	704.00
IUUC-Mga-059875	Meleagris gallopavo	68.59	0.00e+00	1182.00
IUUC-Mvi-060240	Microbotryum violaceum	43.23	0.00e+00	712.00
IUUC-Mmr-061261	Microcebus murinus	67.71	0.00e+00	1167.00
IUUC-Mdo-062076	Monodelphis domestica	67.73	0.00e+00	1182.00
IUUC-Mmu-063324	Mus musculus	64.99	0.00e+00	1166.00
IUUC-Mac-064636	Musa acuminata	53.42	0.00e+00	932.00
IUUC-Mpu-065961	Mustela putorius furo	68.64	0.00e+00	1163.00
IUUC-Mlu-067059	Myotis lucifugus	67.15	0.00e+00	1115.00
IUUC-Nfi-068277	Neosartorya fischeri	45.88	0.00e+00	750.00
IUUC-Ncr-068659	Neurospora crassa	45.33	0.00e+00	729.00
IUUC-Nle-069034	Nomascus leucogenys	67.60	0.00e+00	1164.00
IUUC-Opr-070334	Ochotona princeps	69.14	0.00e+00	1030.00
IUUC-Ont-071563	Oreochromis niloticus	77.38	0.00e+00	1467.00
IUUC-Oan-073416	Ornithorhynchus anatinus	72.08	0.00e+00	1169.00
IUUC-Ocu-074522	Oryctolagus cuniculus	67.22	0.00e+00	1164.00
IUUC-Oba-075760	Oryza barthii	50.77	0.00e+00	848.00
IUUC-Obr-076201	Oryza brachyantha	54.55	0.00e+00	959.00
IUUC-Ogl-077450	Oryza glaberrima	51.96	0.00e+00	876.00
IUUC-Ogu-078994	Oryza glumaepatula	50.77	0.00e+00	847.00
IUUC-Oin-079856	Oryza indica	53.25	0.00e+00	934.00
IUUC-Olo-080731	Oryza longistaminata	49.59	0.00e+00	833.00
IUUC-Ome-081554	Oryza meridionalis	51.93	0.00e+00	890.00
IUUC-Oni-082324	Oryza nivara	50.77	0.00e+00	847.00
IUUC-Opu-083400	Oryza punctata	52.07	0.00e+00	920.00
IUUC-Oru-084829	Oryza rufipogon	50.77	0.00e+00	847.00
IUUC-Osa-086026	Oryza sativa	51.96	0.00e+00	879.00
IUUC-Ola-087245	Oryzias latipes	77.08	0.00e+00	1469.00
IUUC-Olu-087655	Ostreococcus lucimarinus	42.43	0.00e+00	662.00
IUUC-Oga-088163	Otolemur garnettii	73.78	0.00e+00	1324.00
IUUC-Oar-089842	Ovis aries	67.71	0.00e+00	1167.00
IUUC-Ptr-090501	Pan troglodytes	67.60	0.00e+00	1163.00
IUUC-Pan-092011	Papio anubis	67.71	0.00e+00	1165.00
IUUC-Psi-093308	Pelodiscus sinensis	69.13	0.00e+00	1182.00
IUUC-Pma-094695	Petromyzon marinus	77.24	0.00e+00	1338.00
IUUC-Pno-094785	Phaeosphaeria nodorum	49.81	2.00e-73	270.00
IUUC-Ppa-095911	Physcomitrella patens	42.79	0.00e+00	674.00
IUUC-Pfo-096587	Poecilia formosa	76.11	0.00e+00	1463.00
IUUC-Pab-097926	Pongo abelii	65.67	0.00e+00	1086.00
IUUC-Pop-099634	Populus trichocarpa	43.91	0.00e+00	673.00
IUUC-Pca-100965	Procavia capensis	66.15	0.00e+00	1135.00
IUUC-Ppe-101470	Prunus persica	56.33	0.00e+00	969.00
IUUC-Pva-102451	Pteropus vampyrus	78.46	0.00e+00	1050.00
IUUC-Pgr-103453	Puccinia graminis	45.04	0.00e+00	717.00
IUUC-Ptt-103868	Puccinia triticina	45.03	0.00e+00	713.00
IUUC-Pte-104274	Pyrenophora teres	46.36	0.00e+00	753.00
IUUC-Pyt-104794	Pyrenophora triticirepentis	45.59	0.00e+00	705.00
IUUC-Rno-105979	Rattus norvegicus	65.02	0.00e+00	958.00
IUUC-Sce-106269	Saccharomyces cerevisiae	34.30	2.00e-136	479.00
IUUC-Sha-106905	Sarcophilus harrisii	67.66	0.00e+00	1178.00
IUUC-Sja-107838	Schizosaccharomyces japonicus	36.45	5.00e-154	538.00
IUUC-Spo-108299	Schizosaccharomyces pombe	35.92	5.00e-153	535.00
IUUC-Smo-108695	Selaginella moellendorffii	44.60	0.00e+00	666.00
IUUC-Sit-110692	Setaria italica	57.82	0.00e+00	950.00
IUUC-Sly-111525	Solanum lycopersicum	44.91	0.00e+00	713.00
IUUC-Stu-112906	Solanum tuberosum	53.96	0.00e+00	852.00
IUUC-Sar-113472	Sorex araneus	76.70	0.00e+00	945.00
IUUC-Sbi-114052	Sorghum bicolor	57.11	0.00e+00	971.00
IUUC-Sre-115040	Sporisorium reilianum	43.54	0.00e+00	711.00
IUUC-Ssc-115593	Sus scrofa	68.64	0.00e+00	1165.00
IUUC-Tgu-117239	Taeniopygia guttata	67.62	0.00e+00	1188.00
IUUC-Tru-118025	Takifugu rubripes	79.53	0.00e+00	1437.00
IUUC-Tsy-118824	Tarsius syrichta	67.07	0.00e+00	854.00
IUUC-Tni-120142	Tetraodon nigroviridis	79.51	0.00e+00	1440.00
IUUC-Tca-121613	Theobroma cacao	44.94	0.00e+00	701.00
IUUC-Tre-122072	Trichoderma reesei	47.12	0.00e+00	747.00
IUUC-Tvi-122546	Trichoderma virens	46.54	0.00e+00	734.00
IUUC-Tae-125292	Triticum aestivum	51.43	0.00e+00	867.00
IUUC-Tur-126283	Triticum urartu	52.00	0.00e+00	884.00
IUUC-Tme-127041	Tuber melanosporum	41.39	0.00e+00	629.00
IUUC-Tbe-127770	Tupaia belangeri	79.07	0.00e+00	1063.00
IUUC-Ttr-129294	Tursiops truncatus	64.78	0.00e+00	1165.00
IUUC-Uma-129351	Ustilago maydis	46.34	0.00e+00	770.00
IUUC-Vda-129716	Verticillium dahliae	47.36	0.00e+00	764.00
IUUC-Vpa-130037	Vicugna pacos	83.64	0.00e+00	828.00
IUUC-Vvi-131689	Vitis vinifera	45.40	0.00e+00	697.00
IUUC-Xtr-132633	Xenopus tropicalis	67.27	0.00e+00	1146.00
IUUC-Xma-133347	Xiphophorus maculatus	76.51	0.00e+00	1466.00
IUUC-Yli-134455	Yarrowia lipolytica	46.39	0.00e+00	726.00
IUUC-Zma-135867	Zea mays	57.23	0.00e+00	964.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence