iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mlu-067912

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAPE02000010

Gene Name

GNB2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMLUG00000006764.2	ENSMLUT00000006773.2	ENSMLUP00000006184.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.20e-40	135.8	182	220
UBD/Beta-Prp	4.80e-53	180.3	47	268

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvllk 37
           gH+++v +l++ +d +++vsG+ D +ik+WD+r+  + +
   Q: 182  GHSGDVMSLSLaPDgRTFVSGACDASIKLWDVRDSMCRQ 220
           8***********99999****************988866 PP

UBD/Beta-Prp

   S: 44   llrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqclee. 131
           + r+l gh a+++a+ +  d+ +lv++s+D+ + +wd  t   vh++   ++ v+++++ psg++++ G+ d++  ++ l+t++     
   Q: 47   TRRTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNFVACGGLDNICSIYSLKTREGNVRv 135
           56899****************************************************************************99877666 PP
   S: 132  ..tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtl 218
              l gh+g  +c ++ + +n ++++s D+t+ lWd++tg+    + g h ++v sls+ ++g+ +vsg++d ++klwd++ + c +t+
   Q: 136  srELPGHTGYLSCCRFLD-DNQIITSSGDTTCALWDIETGQQTVAFAG-HSGDVMSLSLAPDGRTFVSGACDASIKLWDVRDSMCRQTF 222
           779*************99.7778999********************99.**************************************** PP
   S: 219  nghtdnvksvrfspnderlvsgssDgsiriWdlrsgdllktlqlhn 264
           +gh++ ++ v+f+pn+  + +gs+D + r++dlr ++ l ++++ n
   Q: 223  IGHESDINAVAFFPNGYAFTTGSDDATCRLFDLRADQELLMYSHDN 268
           ***************************************9999854 PP

Organism

Myotis lucifugus

Protein Sequence
(Fasta)

MSELEQLRQE AEQLRNQIRD ARKACGDSTL TQITAGLDPV GRIQMRTRRT LRGHLAKIYA 60
MHWGTDSRLL VSASQDGKLI IWDSYTTNKV HAIPLRSSWV MTCAYAPSGN FVACGGLDNI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CAGGACCTCC CGCGCTTCTC CAGCGACCCT TGGCAGAGTC CCACCGCCAC AGGTACCCGC 60
GCTGACAGAA GGAGTCCTCA CAACCCCCAG CCCCAAATTC CCATGGGGGT GGGGTGGGGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR020472--G-protein_beta_WD-40_rep
IPR001632--Gprotein_B
IPR016346--Guanine_nucleotide-bd_bsu
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00319--GPROTEINB
PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0070062--C:extracellular exosome
GO:0005615--C:extracellular space
GO:0005925--C:focal adhesion
GO:0005765--C:lysosomal membrane
GO:0043209--C:myelin sheath
GO:0048471--C:perinuclear region of cytoplasm
GO:0007165--P:signal transduction

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001395	Ailuropoda melanoleuca	98.76	0.00e+00	657.00
IUUC-Ago-007831	Ashbya gossypii	38.24	3.00e-68	252.00
IUUC-Ame-011124	Astyanax mexicanus	94.12	0.00e+00	639.00
IUUC-Bta-013430	Bos taurus	99.69	0.00e+00	663.00
IUUC-Cel-018704	Caenorhabditis elegans	85.59	2.00e-180	624.00
IUUC-Cja-019794	Callithrix jacchus	99.69	0.00e+00	663.00
IUUC-Cpo-021865	Cavia porcellus	99.69	0.00e+00	663.00
IUUC-Csa-023572	Chlorocebus sabaeus	99.69	0.00e+00	663.00
IUUC-Cin-025309	Ciona intestinalis	80.47	7.00e-170	589.00
IUUC-Csv-026258	Ciona savignyi	80.77	2.00e-170	591.00
IUUC-Cgl-026673	Colletotrichum gloeosporioides	65.50	3.00e-136	477.00
IUUC-Dre-027957	Danio rerio	94.43	0.00e+00	635.00
IUUC-Dno-029001	Dasypus novemcinctus	99.69	0.00e+00	664.00
IUUC-Dor-030322	Dipodomys ordii	88.85	1.00e-166	578.00
IUUC-Eca-034149	Equus caballus	99.69	0.00e+00	663.00
IUUC-Fca-036537	Felis catus	99.69	0.00e+00	663.00
IUUC-Gmo-039332	Gadus morhua	94.74	0.00e+00	635.00
IUUC-Gac-041932	Gasterosteus aculeatus	93.19	0.00e+00	630.00
IUUC-Ggo-044543	Gorilla gorilla	99.69	0.00e+00	663.00
IUUC-Hsa-046432	Homo sapiens	99.69	0.00e+00	663.00
IUUC-Itr-048049	Ictidomys tridecemlineatus	99.70	0.00e+00	684.00
IUUC-Laf-053865	Loxodonta africana	99.69	0.00e+00	663.00
IUUC-Mcc-055781	Macaca mulatta	99.67	0.00e+00	629.00
IUUC-Meu-056902	Macropus eugenii	99.07	0.00e+00	660.00
IUUC-Mor-057188	Magnaporthe oryzae	64.91	4.00e-134	471.00
IUUC-Mla-059086	Melampsora laricipopulina	70.62	2.00e-149	521.00
IUUC-Mmr-061015	Microcebus murinus	99.69	0.00e+00	663.00
IUUC-Mdo-062734	Monodelphis domestica	99.07	0.00e+00	660.00
IUUC-Mmu-063737	Mus musculus	99.69	0.00e+00	663.00
IUUC-Mpu-066784	Mustela putorius furo	99.35	0.00e+00	636.00
IUUC-Opr-070866	Ochotona princeps	99.69	0.00e+00	663.00
IUUC-Ont-072526	Oreochromis niloticus	93.50	0.00e+00	630.00
IUUC-Ocu-074344	Oryctolagus cuniculus	99.69	0.00e+00	663.00
IUUC-Ola-087468	Oryzias latipes	90.71	1.00e-178	619.00
IUUC-Oga-089046	Otolemur garnettii	99.69	0.00e+00	663.00
IUUC-Oar-089822	Ovis aries	93.19	2.00e-176	611.00
IUUC-Ptr-091444	Pan troglodytes	99.69	0.00e+00	663.00
IUUC-Pan-092045	Papio anubis	99.69	0.00e+00	663.00
IUUC-Pma-094748	Petromyzon marinus	91.27	1.00e-139	488.00
IUUC-Pab-097601	Pongo abelii	98.76	0.00e+00	658.00
IUUC-Pca-100940	Procavia capensis	99.69	0.00e+00	663.00
IUUC-Pva-102229	Pteropus vampyrus	99.38	0.00e+00	656.00
IUUC-Rno-106104	Rattus norvegicus	99.69	0.00e+00	663.00
IUUC-Sha-107632	Sarcophilus harrisii	99.07	0.00e+00	660.00
IUUC-Ssc-115595	Sus scrofa	99.69	0.00e+00	663.00
IUUC-Tru-118401	Takifugu rubripes	93.19	0.00e+00	630.00
IUUC-Tni-120216	Tetraodon nigroviridis	92.88	0.00e+00	629.00
IUUC-Tbe-128132	Tupaia belangeri	98.83	1.00e-147	515.00
IUUC-Ttr-128403	Tursiops truncatus	99.69	0.00e+00	663.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence