iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mac-064983

Ensembl Protein ID

GSMUA_Achr10P05960_001

UniProt Accession

M0RFS3; M0RFS3_MUSAM

Protein Name

Uncharacterized protein

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
GSMUA_Achr10G05960_001	GSMUA_Achr10T05960_001	GSMUA_Achr10P05960_001

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E1	3.40e-169	564.3	425	912

Active Site

Position(s)	Description	Evidence
606	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU10132}

Domain Profile

   S: 1    YDRQirlwGeeaqeklksakvllvGagglGcEllKnLvlaGv.....gsitvvDmdtvevsnlnrqFLfraedvgksKAevaaealk 82
           YD Qi ++G++ q+kl+ akv++vG g+lGcE+lKnL+l+Gv     g++t++D+d +e+snl+rqFLfr++++g+ K+ vaa+a+ 
   Q: 425  YDAQISVFGSKLQKKLEDAKVFIVGSGALGCEFLKNLALMGVccspkGKLTITDDDVIEKSNLSRQFLFRDWNIGQAKSTVAAAAAV 511
           *************************************************************************************** PP
   S: 83   elnpdvnveaheesiteleeeiv...FfkkfdvVvlaldnrearrkvnrlclnarvpliesgtlGllGqvrviikgltecyscsddp 166
            +npd ++ea +++ ++++e+++   F + +d V++aldn+ ar++++ +cl+ ++pl+esgtlG + +++ +i++lte y +s+dp
   Q: 512  SINPDLHIEALQNRASPETENVFddgFWESLDAVINALDNVTARMYMDGRCLYFQKPLLESGTLGAKCNTQMVIPHLTENYGASRDP 598
           *********************99**************************************************************** PP
   S: 167  pqktiPfctlketpnaaehtiewa............vlfnklleeeageeevlekldseekeegkdkvkselksedeenfeeaieia 241
           p+k++P+ct+ ++p +++h+++wa              +n +l++ ++      +   ++ ++ ++ v + l + + e+f++++ +a
   Q: 599  PEKQAPMCTVHSFPHNIDHCLTWArsefegllektpNEVNTFLKNPNAYAASMRNAGDAQARNLLEHVLECLDTDRCETFQDCVCWA 685
           *****************************99999998888888888888888889999999999999999999************** PP
   S: 242  vkafakttinsikqllksfecdivtkskspfwv...................................................... 274
           + +f+ +++n +kql+  f+ d  t+ ++pfw+                                                      
   Q: 686  RFKFEDYFSNRVKQLTFTFPEDAATSTGAPFWSapkrfprplqfsssdpshvhfvmsasilraetfgivvpewaknpktlgdavdkv 772
           ****************************************************99999999999999999998888888888888877 PP
   S: 275  ....sfcsnaealqvpekvekdeevvkasap.lylllralerfekk..kgrkpgelsfekddds..avdlvtaaanlraeslgiepk 352
                 ++   ++ ++ek+++  +++ ++a+ +  l+++le+ +kk  +g  ++ ++fekddd   ++dl++ +an+ra ++gi++ 
   Q: 773  lvpdFQPKTGVQIVTDEKATSLSAASIDDAAvINDLIAKLEECAKKlpPGFRMDPIQFEKDDDAnyHMDLIAGLANMRARNYGIQE- 858
           77754444455555667777777777777779999999999999986689************************************. PP
   S: 353  ldddlikeiagniipaiattnavvgGlaaqEviKvvsg..kfeplknfflfdae 404
           +d+ + k iag+iipaiat +a+  Gl+++E++Kv+ g  k e ++n+f ++a+
   Q: 859  VDKLKAKFIAGRIIPAIATSTAMATGLVCLELYKVLAGghKLEDYRNTFANLAL 912
           **************************************99*********99875 PP

Organism

Musa acuminata

Protein Sequence
(Fasta)

MEEENNQANG MEVDEGGRKQ ADIDEDLHSR QLAVYGRETM RRLFASNVLV SGLQGLGAEI 60
AKNLVLAGVK SITLHDEGTV ELWDLSSNFF FSKEDIGKNR ALACVLKLQE LNNAVLVSTL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGAGGAGG AGAACAACCA AGCAAACGGA ATGGAGGTCG ACGAGGGCGG GCGCAAGCAG 60
GCCGATATCG ACGAGGACCT GCACAGCCGG CAGCTGGCGG TGTACGGACG GGAGACCATG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0436--Ligase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR032420--E1_4HB
IPR032418--E1_FCCH
IPR016040--NAD(P)-bd_dom
IPR000594--ThiF_NAD_FAD-bd
IPR018965--Ub-activating_enz_E1_C
IPR019572--UBA_E1_Cys
IPR018075--UBQ-activ_enz_E1
IPR018074--UBQ-activ_enz_E1_CS
IPR033127--UBQ-activ_enz_E1_Cys_AS
IPR000011--UBQ/SUMO-activ_enz_E1-like

PROSITE

PS00536--UBIQUITIN_ACTIVAT_1
PS00865--UBIQUITIN_ACTIVAT_2

Pfam

PF16191--E1_4HB
PF16190--E1_FCCH
PF09358--E1_UFD
PF00899--ThiF
PF10585--UBA_e1_thiolCys

PRINTS

PR01849--UBIQUITINACT

SMART

SM00985--UBA_e1_C

Gene Ontology

GO:0005524--F:ATP binding
GO:0008641--F:small protein activating enzyme activity
GO:0006464--P:cellular protein modification process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Apl-004158	Anas platyrhynchos	40.06	0.00e+00	672.00
IUUC-Cho-024682	Choloepus hoffmanni	34.93	7.00e-99	354.00
IUUC-Ete-033124	Echinops telfairi	40.15	2.00e-130	459.00
IUUC-Fal-036848	Ficedula albicollis	39.86	0.00e+00	681.00
IUUC-Gga-040747	Gallus gallus	40.06	0.00e+00	671.00
IUUC-Mga-059721	Meleagris gallopavo	40.06	0.00e+00	650.00
IUUC-Oan-073268	Ornithorhynchus anatinus	39.33	8.00e-178	617.00
IUUC-Psi-093489	Pelodiscus sinensis	39.76	0.00e+00	669.00
IUUC-Pma-094214	Petromyzon marinus	47.02	3.00e-33	133.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence