iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ggo-045375

UUCD1 version

UUC-GoG-00999

Ensembl Protein ID

ENSGGOP00000017639.1

UniProt Accession

G3RPB9; G3RPB9_GORGO

Protein Name

Uncharacterized protein

Gene Name

UBE2D2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGGOG00000001368.2	ENSGGOT00000027395.1	ENSGGOP00000017639.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	1.10e-55	187.6	8	140
UBD/UBC-like/UBD_UBC	7.60e-84	279.2	8	143

Active Site

Position(s)	Description	Evidence
86	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00388}

Domain Profile

E2/UBC

   S: 3    kkelkelekdppegisakpvdesdltewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltkifhPnvyenGkvClsilkeeek 91
           ++el++l++dpp+++sa+pv + d+++w+++i+Gp+d+pY+ggvF l+i+fp+dYPfkPPkv f+t+i+hPn+++nG++Cl+il+  ++
   Q: 8    QQELNDLARDPPAQCSAGPVGD-DMFHWQATIMGPNDSPYQGGVFFLTIHFPTDYPFKPPKVAFTTRIYHPNINSNGSICLDILR--SQ 93
           79********************.9************************************************************9..** PP
   S: 92   Wspalsvesvllsiqsllaepnpesplneeaaellkknreeykkkvr 138
           Wspal++++vllsi+sll++pnp++pl  e+a+++k++re+y++++r
   Q: 94   WSPALTISKVLLSICSLLCDPNPDDPLVPEIARIYKTDREKYNRIAR 140
           *******************************************9987 PP

UBD/UBC-like/UBD_UBC

   S: 3    kkelkdllrdeeaqisadlvdddlfelratiagppdspyeggvffltiklptdypfkppkvafitkiyhpninsngsicldilrsqwsa 91
           ++el+dl+rd++aq+sa++v+dd+f+++ati+gp+dspy+ggvfflti++ptdypfkppkvaf+t+iyhpninsngsicldilrsqws+
   Q: 8    QQELNDLARDPPAQCSAGPVGDDMFHWQATIMGPNDSPYQGGVFFLTIHFPTDYPFKPPKVAFTTRIYHPNINSNGSICLDILRSQWSP 96
           68*************************************************************************************** PP
   S: 92   altlskvllslcslladaepddplvaeiariyktdkekykriarewt 138
           alt+skvlls+csll+d++pddplv+eiariyktd+eky+riarewt
   Q: 97   ALTISKVLLSICSLLCDPNPDDPLVPEIARIYKTDREKYNRIAREWT 143
           **********************************************8 PP

Organism

Gorilla gorilla

Protein Sequence
(Fasta)

MLLREFHQQE LNDLARDPPA QCSAGPVGDD MFHWQATIMG PNDSPYQGGV FFLTIHFPTD 60
YPFKPPKVAF TTRIYHPNIN SNGSICLDIL RSQWSPALTI SKVLLSICSL LCDPNPDDPL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGCTCTTAA GAGAGTTTCA CCAGCAGGAC AGAGAATATT GGTAACAATA TAAACTTTAG 60
TAATGGATAA AAGGTACATT CATGTTGAAT ATATTTCTTT TCTTTCTTTT TTCTGTAGGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR000608--UBQ-conjugat_E2
IPR023313--UBQ-conjugating_AS
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS00183--UBIQUITIN_CONJUGAT_1
PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00179--UQ_con

Gene Ontology

GO:0070062--C:extracellular exosome
GO:0043234--C:protein complex
GO:0000151--C:ubiquitin ligase complex
GO:0005524--F:ATP binding
GO:0061631--F:ubiquitin conjugating enzyme activity
GO:0051865--P:protein autoubiquitination
GO:0070936--P:protein K48-linked ubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001778	Ailuropoda melanoleuca	99.29	3.00e-81	293.00
IUUC-Apl-003199	Anas platyrhynchos	100.00	3.00e-81	293.00
IUUC-Aca-005236	Anolis carolinensis	95.95	2.00e-82	296.00
IUUC-Ang-009725	Aspergillus niger	84.80	4.00e-62	229.00
IUUC-Bta-013158	Bos taurus	95.95	2.00e-82	296.00
IUUC-Cja-019886	Callithrix jacchus	95.95	2.00e-82	296.00
IUUC-Cfa-020436	Canis familiaris	95.95	2.00e-82	296.00
IUUC-Cpo-021714	Cavia porcellus	93.92	1.00e-80	291.00
IUUC-Csa-023148	Chlorocebus sabaeus	91.95	5.00e-78	282.00
IUUC-Dre-027758	Danio rerio	94.59	3.00e-81	293.00
IUUC-Dno-028952	Dasypus novemcinctus	97.90	6.00e-82	295.00
IUUC-Dor-030285	Dipodomys ordii	97.84	8.00e-80	288.00
IUUC-Ete-032295	Echinops telfairi	100.00	3.00e-81	293.00
IUUC-Eca-033293	Equus caballus	97.22	5.00e-82	295.00
IUUC-Eeu-034766	Erinaceus europaeus	96.43	3.00e-78	283.00
IUUC-Gmo-039620	Gadus morhua	94.24	8.00e-78	281.00
IUUC-Gga-040758	Gallus gallus	95.95	2.00e-82	296.00
IUUC-Gac-042231	Gasterosteus aculeatus	93.24	3.00e-80	290.00
IUUC-Hsa-045885	Homo sapiens	95.95	2.00e-82	296.00
IUUC-Itr-048882	Ictidomys tridecemlineatus	95.95	4.00e-84	302.00
IUUC-Lch-050583	Latimeria chalumnae	90.14	2.00e-74	270.00
IUUC-Loc-052788	Lepisosteus oculatus	98.57	4.00e-81	293.00
IUUC-Laf-053580	Loxodonta africana	99.29	2.00e-81	293.00
IUUC-Mcc-054673	Macaca mulatta	97.92	2.00e-82	297.00
IUUC-Meu-056462	Macropus eugenii	96.40	1.00e-78	284.00
IUUC-Mmr-061474	Microcebus murinus	100.00	3.00e-81	293.00
IUUC-Mdo-062962	Monodelphis domestica	95.95	2.00e-82	296.00
IUUC-Mmu-063518	Mus musculus	95.95	2.00e-82	296.00
IUUC-Mpu-066604	Mustela putorius furo	99.29	1.00e-81	294.00
IUUC-Nle-069800	Nomascus leucogenys	97.16	1.00e-78	284.00
IUUC-Opr-070191	Ochotona princeps	97.84	8.00e-80	288.00
IUUC-Ont-071766	Oreochromis niloticus	94.59	2.00e-81	293.00
IUUC-Ocu-074315	Oryctolagus cuniculus	95.95	2.00e-82	296.00
IUUC-Ola-086331	Oryzias latipes	94.59	2.00e-81	293.00
IUUC-Oga-088477	Otolemur garnettii	96.45	2.00e-80	290.00
IUUC-Ptr-090707	Pan troglodytes	95.95	2.00e-82	296.00
IUUC-Pan-092143	Papio anubis	95.95	2.00e-82	296.00
IUUC-Pma-094405	Petromyzon marinus	94.20	5.00e-75	272.00
IUUC-Pfo-096753	Poecilia formosa	94.59	2.00e-81	293.00
IUUC-Pab-097764	Pongo abelii	95.95	2.00e-82	296.00
IUUC-Ptt-103723	Puccinia triticina	76.71	9.00e-63	232.00
IUUC-Sar-113302	Sorex araneus	100.00	3.00e-81	293.00
IUUC-Tru-118272	Takifugu rubripes	94.59	5.00e-81	292.00
IUUC-Tsy-119491	Tarsius syrichta	97.12	2.00e-76	278.00
IUUC-Tni-120056	Tetraodon nigroviridis	94.59	5.00e-81	292.00
IUUC-Tbe-127609	Tupaia belangeri	100.00	1.00e-67	247.00
IUUC-Vpa-130446	Vicugna pacos	96.53	2.00e-80	291.00
IUUC-Xtr-132329	Xenopus tropicalis	95.95	2.00e-82	296.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence