iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Pab-098416

Ensembl Protein ID

ENSPPYP00000021455.2

UniProt Accession

H2PRZ0; H2PRZ0_PONAB

Genbank Protein ID

ENSPPYP00000021455

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ABGA01289223

Gene Name

DDX58

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPPYG00000019149.2	ENSPPYT00000022324.2	ENSPPYP00000021455.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/CARD	2.30e-33	114.6	51	122

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/CARD

   S: 3    eeyrlllstlqdrvrklLdvtdvldkylseflleeekelilaaaetkgnmqaaelLLktL..vqkegWfrefl 73
           eeyrlll++lq+++++++++td+++ +lse+l+++e+e+il++++tkg+m++ae+L+++L  ++ke+W+++++
   Q: 51   EEYRLLLKRLQPEFKTRIIPTDIIS-DLSECLINQECEEILQICSTKGMMAGAEKLVECLlrSDKENWPKTLK 122
           9************************.********************************************985 PP

Organism

Pongo abelii

Protein Sequence
(Fasta)

MEAATLFLKF LLELQEEGWF RGFLDALDHA GYSGLYEAIE SWDFKKIEKL EEYRLLLKRL 60
QPEFKTRIIP TDIISDLSEC LINQECEEIL QICSTKGMMA GAEKLVECLL RSDKENWPKT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGGTCGCAGC CGCCGCTGGG GTCTCCGCTG TCTCGCGAGG AGGGTGAAGC GCCCCCGCCT 60
GCTCCCGCTT CGGAGGGTAG GCGGAGAAGT CGCCGGGTAC GCCTTCGCGG ATCCTGCCGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0862--Zinc

Interpro

IPR031964--CARD_dom
IPR011545--DEAD/DEAH_box_helicase_dom
IPR011029--DEATH-like_dom
IPR014001--Helicase_ATP-bd
IPR001650--Helicase_C
IPR027417--P-loop_NTPase
IPR021673--RLR_CTR

PROSITE

PS51192--HELICASE_ATP_BIND_1
PS51194--HELICASE_CTER
PS51789--RLR_CTR

Pfam

PF16739--CARD_2
PF00270--DEAD
PF00271--Helicase_C
PF11648--RIG-I_C-RD

SMART

SM00487--DEXDc
SM00490--HELICc

Gene Ontology

GO:0015629--C:actin cytoskeleton
GO:0005923--C:bicellular tight junction
GO:0005829--C:cytosol
GO:0032587--C:ruffle membrane
GO:0005524--F:ATP binding
GO:0003690--F:double-stranded DNA binding
GO:0003725--F:double-stranded RNA binding
GO:0016817--F:hydrolase activity, acting on acid anhydrides
GO:0003727--F:single-stranded RNA binding
GO:0008270--F:zinc ion binding
GO:0009597--P:detection of virus
GO:0045087--P:innate immune response
GO:0002230--P:positive regulation of defense response to virus by host
GO:0032725--P:positive regulation of granulocyte macrophage colony-stimulating factor production
GO:0032727--P:positive regulation of interferon-alpha production
GO:0032728--P:positive regulation of interferon-beta production
GO:0032755--P:positive regulation of interleukin-6 production
GO:0032757--P:positive regulation of interleukin-8 production
GO:0042993--P:positive regulation of transcription factor import into nucleus
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter
GO:0030334--P:regulation of cell migration
GO:0043330--P:response to exogenous dsRNA
GO:0039529--P:RIG-I signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001898	Ailuropoda melanoleuca	80.11	0.00e+00	1405.00
IUUC-Apl-003966	Anas platyrhynchos	53.97	0.00e+00	915.00
IUUC-Aca-004499	Anolis carolinensis	46.76	0.00e+00	768.00
IUUC-Ame-011950	Astyanax mexicanus	44.98	0.00e+00	682.00
IUUC-Bta-012489	Bos taurus	80.23	0.00e+00	1366.00
IUUC-Cel-018230	Caenorhabditis elegans	29.21	5.00e-71	263.00
IUUC-Cja-018716	Callithrix jacchus	93.83	0.00e+00	1639.00
IUUC-Cfa-020269	Canis familiaris	81.91	0.00e+00	1454.00
IUUC-Cpo-022507	Cavia porcellus	77.19	0.00e+00	1365.00
IUUC-Csa-024209	Chlorocebus sabaeus	95.89	0.00e+00	1682.00
IUUC-Cho-025104	Choloepus hoffmanni	73.98	0.00e+00	1182.00
IUUC-Cin-025792	Ciona intestinalis	31.32	6.00e-79	288.00
IUUC-Cgl-026385	Colletotrichum gloeosporioides	25.28	3.00e-23	104.00
IUUC-Dno-028954	Dasypus novemcinctus	79.02	0.00e+00	1344.00
IUUC-Eca-034039	Equus caballus	82.17	0.00e+00	1446.00
IUUC-Eeu-035009	Erinaceus europaeus	70.32	0.00e+00	931.00
IUUC-Fca-036169	Felis catus	82.63	0.00e+00	1467.00
IUUC-Fal-037579	Ficedula albicollis	54.83	0.00e+00	928.00
IUUC-Ggo-045318	Gorilla gorilla	94.75	0.00e+00	1606.00
IUUC-Hsa-046671	Homo sapiens	98.74	0.00e+00	1699.00
IUUC-Itr-047996	Ictidomys tridecemlineatus	78.81	0.00e+00	1358.00
IUUC-Lch-050461	Latimeria chalumnae	51.47	0.00e+00	870.00
IUUC-Loc-052582	Lepisosteus oculatus	49.66	0.00e+00	832.00
IUUC-Laf-054324	Loxodonta africana	79.30	0.00e+00	1359.00
IUUC-Mcc-055390	Macaca mulatta	95.20	0.00e+00	1665.00
IUUC-Meu-056365	Macropus eugenii	55.08	2.00e-178	619.00
IUUC-Mmr-061407	Microcebus murinus	85.84	0.00e+00	1530.00
IUUC-Mmu-063939	Mus musculus	76.46	0.00e+00	1329.00
IUUC-Mpu-066226	Mustela putorius furo	79.83	0.00e+00	1378.00
IUUC-Mlu-068092	Myotis lucifugus	81.50	0.00e+00	1389.00
IUUC-Nfi-068405	Neosartorya fischeri	24.66	4.00e-26	114.00
IUUC-Opr-070246	Ochotona princeps	68.92	0.00e+00	689.00
IUUC-Oan-072742	Ornithorhynchus anatinus	61.56	0.00e+00	979.00
IUUC-Ocu-073959	Oryctolagus cuniculus	77.05	0.00e+00	1375.00
IUUC-Oga-089173	Otolemur garnettii	84.13	0.00e+00	1466.00
IUUC-Oar-089369	Ovis aries	79.20	0.00e+00	1326.00
IUUC-Ptr-091032	Pan troglodytes	98.74	0.00e+00	1699.00
IUUC-Pan-092383	Papio anubis	95.66	0.00e+00	1670.00
IUUC-Psi-093432	Pelodiscus sinensis	57.42	0.00e+00	1016.00
IUUC-Pma-094367	Petromyzon marinus	43.01	3.00e-118	418.00
IUUC-Pca-101006	Procavia capensis	76.96	0.00e+00	632.00
IUUC-Pva-102966	Pteropus vampyrus	83.20	0.00e+00	1452.00
IUUC-Pgr-103529	Puccinia graminis	27.27	8.00e-28	119.00
IUUC-Rno-105059	Rattus norvegicus	76.01	0.00e+00	824.00
IUUC-Ssl-108450	Sclerotinia sclerotiorum	27.55	1.00e-04	43.90
IUUC-Sar-113202	Sorex araneus	69.09	0.00e+00	976.00
IUUC-Ssc-116120	Sus scrofa	78.27	0.00e+00	1320.00
IUUC-Tgu-117314	Taeniopygia guttata	53.84	0.00e+00	911.00
IUUC-Tsy-119453	Tarsius syrichta	84.26	0.00e+00	895.00
IUUC-Tre-122194	Trichoderma reesei	26.54	7.00e-20	93.20
IUUC-Ttr-128421	Tursiops truncatus	77.93	0.00e+00	1210.00
IUUC-Vpa-130602	Vicugna pacos	78.31	0.00e+00	1358.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence