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Tag Content
iUUCD ID IUUC-Oan-073526
Ensembl Protein ID ENSOANP00000001512.3
UniProt Accession F6YHH1; F6YHH1_ORNAN
Protein Name Tyrosine-protein kinase
Gene Name ABL2
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSOANG00000000958.3 ENSOANT00000001513.3 ENSOANP00000001512.3
Status Unreviewed
Classification
Family E-Value Score Start End
UBD/SH3 2.30e-12 46.9 64 121
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   UBD/SH3
   S: 3    kekvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekle 63
            +++ +lyd+ a+ d++L+++kG++++v+  ++q+++W +     ++ +G +P+n+++ ++
   Q: 64   PNLFVALYDFVASGDNTLSITKGEKLRVL-GYNQNGEWSEV--RSKNGQGWVPSNYITPVN 121
           67899************************.*********98..788899*********997 PP
   
Organism Ornithorhynchus anatinus
Protein Sequence
(Fasta)
MLEIFQVLMF MLQLLTCHCI SRVSTDKKEA LHRPYGCDVE PQALNEAIRW SSKENLLGAT 60
ESDPNLFVAL YDFVASGDNT LSITKGEKLR VLGYNQNGEW SEVRSKNGQG WVPSNYITPV 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Oan-073526|UBD,SH3|Ornithorhynchus anatinus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
TTTGGTGACC TCAGTTTTTT TTATTTTAAA TGCTTGAAAT TTTTCAGGTC TTGATGTTTA 60
TGCTTCAACT GCTTACCTGT CACTGCATAT CCCGTGTCAG TACAGATAAA AAAGGTATCG 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Oan-073526|UBD,SH3|Ornithorhynchus anatinus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0728--SH3 domain
KW-0732--Signal
KW-0808--Transferase
KW-0829--Tyrosine-protein kinase
Interpro

IPR015015--F-actin_binding
IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR001245--Ser-Thr/Tyr_kinase_cat_dom
IPR000980--SH2
IPR001452--SH3_domain
IPR008266--Tyr_kinase_AS
IPR020635--Tyr_kinase_cat_dom
PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00109--PROTEIN_KINASE_TYR
PS50001--SH2
PS50002--SH3
Pfam

PF08919--F_actin_bind
PF07714--Pkinase_Tyr
PF00017--SH2
PF00018--SH3_1
PRINTS

PR00401--SH2DOMAIN
PR00109--TYRKINASE
SMART

SM00808--FABD
SM00252--SH2
SM00326--SH3
SM00219--TyrKc
Gene Ontology

GO:0031234--C:extrinsic component of cytoplasmic side of plasma membrane
GO:0005524--F:ATP binding
GO:0000287--F:magnesium ion binding
GO:0030145--F:manganese ion binding
GO:0004715--F:non-membrane spanning protein tyrosine kinase activity
GO:0005102--F:receptor binding
GO:0030154--P:cell differentiation
GO:0071300--P:cellular response to retinoic acid
GO:0045087--P:innate immune response
GO:0038083--P:peptidyl-tyrosine autophosphorylation
GO:0007204--P:positive regulation of cytosolic calcium ion concentration
GO:0010976--P:positive regulation of neuron projection development
GO:0051353--P:positive regulation of oxidoreductase activity
GO:0010863--P:positive regulation of phospholipase C activity
GO:0042127--P:regulation of cell proliferation
GO:0007169--P:transmembrane receptor protein tyrosine kinase signaling pathway
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-002263 Ailuropoda melanoleuca 88.68 0.00e+00 1832.00
IUUC-Atr-002778 Amborella trichopoda 32.99 3.00e-23 103.00
IUUC-Apl-003389 Anas platyrhynchos 86.36 0.00e+00 1731.00
IUUC-Aly-005867 Arabidopsis lyrata 29.12 8.00e-19 88.60
IUUC-Ath-006978 Arabidopsis thaliana 29.12 5.00e-19 89.40
IUUC-Ame-010629 Astyanax mexicanus 58.14 0.00e+00 1056.00
IUUC-Bta-013370 Bos taurus 89.04 0.00e+00 1808.00
IUUC-Bdi-014324 Brachypodium distachyon 33.50 3.00e-23 103.00
IUUC-Cja-018894 Callithrix jacchus 88.30 0.00e+00 1818.00
IUUC-Cfa-020398 Canis familiaris 96.09 0.00e+00 1218.00
IUUC-Cpo-022367 Cavia porcellus 81.61 0.00e+00 1625.00
IUUC-Csa-023386 Chlorocebus sabaeus 88.31 0.00e+00 1819.00
IUUC-Cho-024714 Choloepus hoffmanni 91.98 0.00e+00 1379.00
IUUC-Dre-027741 Danio rerio 67.50 0.00e+00 1372.00
IUUC-Dno-029246 Dasypus novemcinctus 88.43 0.00e+00 1794.00
IUUC-Dor-030416 Dipodomys ordii 81.38 0.00e+00 1632.00
IUUC-Ete-032899 Echinops telfairi 67.61 0.00e+00 733.00
IUUC-Eca-033387 Equus caballus 88.67 0.00e+00 1801.00
IUUC-Eeu-035058 Erinaceus europaeus 81.12 0.00e+00 1699.00
IUUC-Fca-036578 Felis catus 81.96 0.00e+00 1608.00
IUUC-Fal-037491 Ficedula albicollis 90.00 0.00e+00 1859.00
IUUC-Gmo-038509 Gadus morhua 76.74 0.00e+00 1119.00
IUUC-Gga-040638 Gallus gallus 88.82 0.00e+00 1802.00
IUUC-Gac-042550 Gasterosteus aculeatus 77.14 0.00e+00 1179.00
IUUC-Gma-043938 Glycine max 32.00 6.00e-23 102.00
IUUC-Ggo-044487 Gorilla gorilla 88.32 0.00e+00 1815.00
IUUC-Hsa-046636 Homo sapiens 88.41 0.00e+00 1814.00
IUUC-Itr-048685 Ictidomys tridecemlineatus 88.95 0.00e+00 1818.00
IUUC-Lch-049530 Latimeria chalumnae 78.74 0.00e+00 1583.00
IUUC-Lpe-051291 Leersia perrieri 29.24 1.00e-22 101.00
IUUC-Loc-051933 Lepisosteus oculatus 76.14 0.00e+00 1348.00
IUUC-Laf-053802 Loxodonta africana 87.62 0.00e+00 1846.00
IUUC-Mcc-054836 Macaca mulatta 88.41 0.00e+00 1823.00
IUUC-Mtr-057869 Medicago truncatula 31.84 8.00e-21 95.10
IUUC-Mga-059277 Meleagris gallopavo 89.34 0.00e+00 1810.00
IUUC-Mmr-061206 Microcebus murinus 87.96 0.00e+00 1733.00
IUUC-Mdo-062281 Monodelphis domestica 96.92 0.00e+00 1210.00
IUUC-Mmu-063847 Mus musculus 87.43 0.00e+00 1723.00
IUUC-Mac-064649 Musa acuminata 33.66 1.00e-22 101.00
IUUC-Mpu-066309 Mustela putorius furo 95.93 0.00e+00 1217.00
IUUC-Mlu-068070 Myotis lucifugus 88.14 0.00e+00 1805.00
IUUC-Nle-070062 Nomascus leucogenys 96.25 0.00e+00 1222.00
IUUC-Opr-070534 Ochotona princeps 83.03 0.00e+00 979.00
IUUC-Ont-072440 Oreochromis niloticus 65.87 0.00e+00 1326.00
IUUC-Ocu-074051 Oryctolagus cuniculus 87.41 0.00e+00 1764.00
IUUC-Oba-074988 Oryza barthii 30.81 3.00e-19 90.10
IUUC-Ome-081788 Oryza meridionalis 28.92 5.00e-27 115.00
IUUC-Oni-082734 Oryza nivara 34.09 7.00e-24 105.00
IUUC-Opu-083538 Oryza punctata 34.84 1.00e-23 104.00
IUUC-Oga-088767 Otolemur garnettii 82.71 0.00e+00 1628.00
IUUC-Oar-089800 Ovis aries 89.04 0.00e+00 1808.00
IUUC-Ptr-090857 Pan troglodytes 96.25 0.00e+00 1221.00
IUUC-Pan-092279 Papio anubis 88.87 0.00e+00 1815.00
IUUC-Psi-093573 Pelodiscus sinensis 90.08 0.00e+00 1795.00
IUUC-Pfo-096543 Poecilia formosa 76.17 0.00e+00 1134.00
IUUC-Pab-097949 Pongo abelii 88.07 0.00e+00 1774.00
IUUC-Pop-099554 Populus trichocarpa 32.50 2.00e-23 104.00
IUUC-Pca-100370 Procavia capensis 86.84 0.00e+00 1340.00
IUUC-Ppe-101625 Prunus persica 33.82 8.00e-21 95.10
IUUC-Pva-103220 Pteropus vampyrus 81.95 0.00e+00 1578.00
IUUC-Rno-105924 Rattus norvegicus 85.44 0.00e+00 1718.00
IUUC-Sha-107114 Sarcophilus harrisii 88.37 0.00e+00 1383.00
IUUC-Smo-109661 Selaginella moellendorffii 29.50 4.00e-23 101.00
IUUC-Sit-110219 Setaria italica 30.61 9.00e-22 98.20
IUUC-Sbi-114480 Sorghum bicolor 33.64 9.00e-25 108.00
IUUC-Ssc-115968 Sus scrofa 88.77 0.00e+00 1828.00
IUUC-Tgu-117301 Taeniopygia guttata 89.62 0.00e+00 1813.00
IUUC-Tru-118410 Takifugu rubripes 68.55 0.00e+00 1369.00
IUUC-Tni-119991 Tetraodon nigroviridis 72.97 0.00e+00 1245.00
IUUC-Tca-121389 Theobroma cacao 34.87 1.00e-24 107.00
IUUC-Tae-122912 Triticum aestivum 29.68 5.00e-20 92.40
IUUC-Tur-126643 Triticum urartu 31.01 9.00e-20 91.70
IUUC-Tbe-127362 Tupaia belangeri 91.98 0.00e+00 1421.00
IUUC-Ttr-129291 Tursiops truncatus 88.03 0.00e+00 1818.00
IUUC-Vpa-130800 Vicugna pacos 90.38 0.00e+00 1469.00
IUUC-Vvi-131057 Vitis vinifera 31.84 2.00e-23 103.00
IUUC-Xtr-132965 Xenopus tropicalis 70.63 0.00e+00 1407.00
IUUC-Xma-134311 Xiphophorus maculatus 67.01 0.00e+00 1277.00
Created Date 25-Jun-2017

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