iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ncr-068951

Ensembl Protein ID

EAA35783

UniProt Accession

Q7SG04; Q7SG04_NEUCR

Genbank Protein ID

EAA35783.2

Protein Name

WD-repeat containing protein slp1

Genbank Nucleotide ID

CM002236

Gene Name

NCU02616

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
NCU02616	EAA35783	EAA35783

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.40e-20	71.6	419	452
E3 adaptor/Cullin RING/APC_C/CDC20	2.90e-126	419.9	284	584

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdDgtikvWDlrtg 33
           Ht++v++l++ sd   l++G++D+ + +WD r+ 
   Q: 419  HTSEVCGLEWrSDgAQLATGGNDNLVSIWDARSL 452
           ***********99899**************8765 PP

E3 adaptor/Cullin RING/APC_C/CDC20

   S: 1    pekvldapelrddfylnLldWssknvlavaLgssvylwsaktgdvskladleekdlvtsvswieegtllavGtkkgeveiyDveekkkvrtltghsarvga 101
           pe+vldap l dd+ylnLldWss n++a++L+++vy+wsa++g+v  l +++++++v+sv+w+ +g ++ vG  +gev+i+Dv+e  k+r++ gh +rvg 
   Q: 284  PERVLDAPGLIDDYYLNLLDWSSGNQVAIGLERNVYVWSADEGSVNCLLETSPDTYVSSVKWSGDGAYVGVGLGTGEVQIWDVAEGIKIRSMFGHDSRVGV 384
           689************************************************************************************************** PP
   S: 102  LsWnaevlssGsrdgeilhrdvrvkelklstlqahaqevCGlkwnedaklLasGGnDnsvsvwdassse.PlkkfkehkaavkaiawsPwqkslLasGGGt 201
           + W +++ls+G r+g +  +dvr++e+k++ l +h++evCGl+w++d+ +La+GGnDn vs+wda+s   P +++++hkaavka+aw+Pw+ +lLa+GGG+
   Q: 385  MGWSKHLLSTGARSGLVFNHDVRIAEHKVAELVSHTSEVCGLEWRSDGAQLATGGNDNLVSIWDARSLAvPKFTKTNHKAAVKALAWCPWNINLLATGGGA 485
           *******************************************************************999******************************* PP
   S: 202  aDrcikfwntltgalleeidtgsqvcsllwskkskelvsthGfaenkitlwkypslskvaelkgheaRvlslalspdgeaivtaagDetlrfwklfdkk 300
            Dr+i+fwnt++ga++++idtgsqv+sl ws++++e+vs+ G+++n++++w+yp+l + +e+ +he+Rvl++ lspdg+ ++taa+De+l+fwk+f+kk
   Q: 486  YDRHIHFWNTTSGARVNSIDTGSQVTSLRWSPRYREIVSSSGYPDNSLSIWSYPTLVRNVEIPAHESRVLHSCLSPDGQMLATAAADESLKFWKIFEKK 584
           *************************************************************************************************97 PP

Organism

Neurospora crassa

Protein Sequence
(Fasta)

MVTVTNMATP SVTTPKKSHT GLFSSRTAGG RVPLTPSPHH NANVNSSPFN KDKTSNDGQR 60
APAKTVYPGN ISSQLARAAS TKTNWDSPKS NIARGASTPK KALELGVSEF TLTGTGAQAQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTCCTTCCAA TCCATCACAA CCACAATTCC ACGCTGCAAG AAAACCACTT CTGCGCCTCT 60
TGGCCCGTCT TTGATTGCTC TCCTCAAGCC TCTGCTTCTT TCTTGCAACT ATTCGCATAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR024977--Apc4_WD40_dom
IPR033010--Cdc20/Fizzy
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12894--ANAPC4_WD40
PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0032153--C:cell division site
GO:0033597--C:mitotic checkpoint complex
GO:0072686--C:mitotic spindle
GO:0044732--C:mitotic spindle pole body
GO:0097027--F:ubiquitin-protein transferase activator activity
GO:0031145--P:anaphase-promoting complex-dependent catabolic process
GO:0034613--P:cellular protein localization
GO:0000070--P:mitotic sister chromatid segregation
GO:1904668--P:positive regulation of ubiquitin protein ligase activity

KEGG

ncr:NCU02616

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001545	Ailuropoda melanoleuca	44.30	2.00e-90	324.00
IUUC-Apl-003255	Anas platyrhynchos	41.69	6.00e-95	339.00
IUUC-Ago-007962	Ashbya gossypii	44.53	7.00e-94	336.00
IUUC-Acl-008043	Aspergillus clavatus	67.68	0.00e+00	792.00
IUUC-Afl-008593	Aspergillus flavus	68.30	0.00e+00	794.00
IUUC-Afu-008793	Aspergillus fumigatus	68.75	0.00e+00	792.00
IUUC-Ani-009158	Aspergillus nidulans	68.54	0.00e+00	793.00
IUUC-Ang-009786	Aspergillus niger	77.05	0.00e+00	710.00
IUUC-Aor-010163	Aspergillus oryzae	68.30	0.00e+00	794.00
IUUC-Ate-010479	Aspergillus terreus	67.31	0.00e+00	785.00
IUUC-Bgr-012059	Blumeria graminis	68.65	0.00e+00	808.00
IUUC-Bta-012625	Bos taurus	43.77	5.00e-91	326.00
IUUC-Bci-013607	Botrytis cinerea	70.82	0.00e+00	840.00
IUUC-Cja-019132	Callithrix jacchus	42.09	3.00e-93	333.00
IUUC-Cfa-020780	Canis familiaris	44.56	2.00e-91	327.00
IUUC-Cpo-022223	Cavia porcellus	41.67	5.00e-83	300.00
IUUC-Csa-023666	Chlorocebus sabaeus	41.88	2.00e-92	330.00
IUUC-Cin-025675	Ciona intestinalis	41.34	3.00e-88	317.00
IUUC-Cgl-026465	Colletotrichum gloeosporioides	79.22	0.00e+00	900.00
IUUC-Cne-026872	Cryptococcus neoformans	50.94	5.00e-109	386.00
IUUC-Cme-027234	Cyanidioschyzon merolae	45.48	4.00e-94	336.00
IUUC-Dre-028026	Danio rerio	41.92	5.00e-92	329.00
IUUC-Dno-028865	Dasypus novemcinctus	43.11	9.00e-90	322.00
IUUC-Dor-030958	Dipodomys ordii	42.31	3.00e-87	313.00
IUUC-Dse-031391	Dothistroma septosporum	63.38	0.00e+00	712.00
IUUC-Ete-032387	Echinops telfairi	38.03	4.00e-83	300.00
IUUC-Fca-036346	Felis catus	43.89	2.00e-80	290.00
IUUC-Fal-037558	Ficedula albicollis	44.08	7.00e-96	342.00
IUUC-Fox-037850	Fusarium oxysporum	74.63	0.00e+00	841.00
IUUC-Fso-038375	Fusarium solani	76.89	0.00e+00	864.00
IUUC-Gmo-039284	Gadus morhua	44.77	2.00e-90	324.00
IUUC-Ggr-039864	Gaeumannomyces graminis	75.37	0.00e+00	871.00
IUUC-Gac-041431	Gasterosteus aculeatus	42.07	1.00e-83	301.00
IUUC-Ggo-045052	Gorilla gorilla	41.67	2.00e-92	331.00
IUUC-Hsa-046305	Homo sapiens	41.67	2.00e-92	331.00
IUUC-Itr-048461	Ictidomys tridecemlineatus	41.67	9.00e-83	298.00
IUUC-Lma-052998	Leptosphaeria maculans	64.63	0.00e+00	756.00
IUUC-Laf-053742	Loxodonta africana	44.56	2.00e-91	327.00
IUUC-Mcc-054948	Macaca mulatta	41.88	2.00e-92	330.00
IUUC-Mor-057277	Magnaporthe oryzae	75.74	0.00e+00	844.00
IUUC-Mpo-057624	Magnaporthe poae	75.53	0.00e+00	855.00
IUUC-Mla-059066	Melampsora laricipopulina	45.83	1.00e-102	365.00
IUUC-Mvi-060422	Microbotryum violaceum	46.65	2.00e-109	387.00
IUUC-Mmr-061615	Microcebus murinus	41.88	2.00e-92	331.00
IUUC-Mdo-061982	Monodelphis domestica	42.00	1.00e-74	273.00
IUUC-Mmu-063864	Mus musculus	44.05	6.00e-87	312.00
IUUC-Mpu-066502	Mustela putorius furo	44.30	1.00e-95	341.00
IUUC-Mlu-067277	Myotis lucifugus	45.32	9.00e-93	332.00
IUUC-Nfi-068375	Neosartorya fischeri	68.59	0.00e+00	792.00
IUUC-Nle-070149	Nomascus leucogenys	41.67	1.00e-90	325.00
IUUC-Ont-071660	Oreochromis niloticus	41.21	2.00e-83	301.00
IUUC-Ocu-073797	Oryctolagus cuniculus	42.99	9.00e-93	332.00
IUUC-Ola-086907	Oryzias latipes	41.10	1.00e-83	301.00
IUUC-Olu-087647	Ostreococcus lucimarinus	43.92	3.00e-101	360.00
IUUC-Oga-088184	Otolemur garnettii	44.95	1.00e-89	321.00
IUUC-Oar-090023	Ovis aries	43.15	7.00e-87	312.00
IUUC-Ptr-090935	Pan troglodytes	44.85	5.00e-91	326.00
IUUC-Pan-091845	Papio anubis	41.88	2.00e-92	330.00
IUUC-Psi-093188	Pelodiscus sinensis	43.69	4.00e-96	343.00
IUUC-Pma-094187	Petromyzon marinus	38.97	3.00e-81	294.00
IUUC-Pno-094809	Phaeosphaeria nodorum	63.92	0.00e+00	739.00
IUUC-Pab-098603	Pongo abelii	41.88	2.00e-92	331.00
IUUC-Pca-101062	Procavia capensis	44.30	6.00e-90	322.00
IUUC-Pva-102925	Pteropus vampyrus	44.81	7.00e-92	329.00
IUUC-Pgr-103627	Puccinia graminis	45.50	2.00e-96	344.00
IUUC-Pte-104142	Pyrenophora teres	63.05	0.00e+00	706.00
IUUC-Pyt-104693	Pyrenophora triticirepentis	63.05	0.00e+00	707.00
IUUC-Rno-106005	Rattus norvegicus	42.76	1.00e-87	315.00
IUUC-Sce-106360	Saccharomyces cerevisiae	44.44	6.00e-96	343.00
IUUC-Sha-107472	Sarcophilus harrisii	44.53	5.00e-88	316.00
IUUC-Sja-107919	Schizosaccharomyces japonicus	64.72	6.00e-145	505.00
IUUC-Spo-108075	Schizosaccharomyces pombe	62.29	2.00e-139	486.00
IUUC-Ssl-108507	Sclerotinia sclerotiorum	70.82	0.00e+00	833.00
IUUC-Sar-113092	Sorex araneus	41.43	6.00e-83	299.00
IUUC-Sre-114976	Sporisorium reilianum	46.19	1.00e-88	318.00
IUUC-Ssc-115710	Sus scrofa	41.67	4.00e-92	330.00
IUUC-Tgu-117100	Taeniopygia guttata	43.54	1.00e-95	342.00
IUUC-Tru-118184	Takifugu rubripes	44.08	9.00e-82	295.00
IUUC-Tsy-118931	Tarsius syrichta	40.26	2.00e-59	221.00
IUUC-Tni-120474	Tetraodon nigroviridis	44.63	2.00e-84	304.00
IUUC-Tre-122211	Trichoderma reesei	79.66	0.00e+00	762.00
IUUC-Tvi-122531	Trichoderma virens	70.94	0.00e+00	818.00
IUUC-Tme-126905	Tuber melanosporum	59.90	0.00e+00	662.00
IUUC-Tbe-127384	Tupaia belangeri	49.64	4.00e-83	300.00
IUUC-Ttr-128511	Tursiops truncatus	43.41	5.00e-92	329.00
IUUC-Uma-129318	Ustilago maydis	46.07	6.00e-89	319.00
IUUC-Vda-129993	Verticillium dahliae	76.84	0.00e+00	902.00
IUUC-Vpa-130775	Vicugna pacos	39.74	8.00e-61	226.00
IUUC-Xma-133332	Xiphophorus maculatus	39.80	4.00e-83	300.00
IUUC-Yli-134501	Yarrowia lipolytica	58.49	7.00e-150	521.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence