iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mpu-066466

Ensembl Protein ID

ENSMPUP00000011970.1

UniProt Accession

M3YKW3; M3YKW3_MUSPF

Genbank Protein ID

ENSMPUP00000011970

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AEYP01043592

Gene Name

Bmi1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMPUG00000012062.1	ENSMPUT00000012165.1	ENSMPUP00000011970.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	2.50e-06	27.9	18	57
ULD/UDP/UFD/RAWUL	1.10e-30	105.9	131	226

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           C +C   f d + +  C H f+++C+ ++        ++ +CP+C+
   Q: 18   CVLCGGYFIDATTIIECLHSFCKTCIVRY------LETSKYCPICD 57
           ********99999****************......**********5 PP

ULD/UDP/UFD/RAWUL

   S: 1    islsLeplesnkakddsk..........lkkkylrcsarltVkhlkkflaeklklsssyevdllcedevLednetLeeikyifiwkkeg 79
           isls+e++++n+ +++ +          ++k+ylrc+a++tV+hl+kfl++k+++++++++d+++e+e+L+d++tL++i+yi++w+++g
   Q: 131  ISLSIEFFDQNRLDRKVNkdkekakeevNDKRYLRCPAAMTVMHLRKFLRSKMDIPNTFQIDVMYEEEPLKDYYTLMDIAYIYTWRRNG 219
           7899999999999887778889999999************************************************************* PP
   S: 80   pLvLqYr 86
           pL+L+Yr
   Q: 220  PLPLKYR 226
           ******9 PP

Organism

Mustela putorius furo

Protein Sequence
(Fasta)

MHRTTRIKIT ELNPHLMCVL CGGYFIDATT IIECLHSFCK TCIVRYLETS KYCPICDVQV 60
HKTRPLLNIR SDKTLQDIVY KLVPGLFKNE MKRRRDFYAA HPSADAANGS NEDRGEVADE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGCATTTTAT CAAGCAGAAA TGCATCGAAC AACCAGAATC AAGATCACGG AGCTAAATCC 60
CCACCTCATG TGTGTGCTCT GTGGAGGGTA CTTCATTGAT GCCACGACCA TAATAGAATG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR032443--RAWUL
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF16207--RAWUL

SMART

SM00184--RING

Gene Ontology

GO:0000792--C:heterochromatin
GO:0016604--C:nuclear body
GO:0031519--C:PcG protein complex
GO:0000151--C:ubiquitin ligase complex
GO:1990841--F:promoter-specific chromatin binding
GO:0000978--F:RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0097027--F:ubiquitin-protein transferase activator activity
GO:0008270--F:zinc ion binding
GO:0007420--P:brain development
GO:0006306--P:DNA methylation
GO:0048704--P:embryonic skeletal system morphogenesis
GO:0016573--P:histone acetylation
GO:0016574--P:histone ubiquitination
GO:0006959--P:humoral immune response
GO:0001701--P:in utero embryonic development
GO:2001234--P:negative regulation of apoptotic signaling pathway
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0030890--P:positive regulation of B cell proliferation
GO:0033092--P:positive regulation of immature T cell proliferation in thymus
GO:2000011--P:regulation of adaxial/abaxial pattern formation
GO:0021903--P:rostrocaudal neural tube patterning
GO:0048103--P:somatic stem cell division

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000603	Aegilops tauschii	37.21	5.00e-12	65.50
IUUC-Aml-001498	Ailuropoda melanoleuca	99.39	2.00e-171	594.00
IUUC-Apl-004208	Anas platyrhynchos	94.10	1.00e-134	471.00
IUUC-Aca-004661	Anolis carolinensis	83.44	5.00e-140	489.00
IUUC-Ath-007649	Arabidopsis thaliana	42.50	3.00e-12	66.60
IUUC-Ame-010610	Astyanax mexicanus	73.25	6.00e-139	486.00
IUUC-Bta-012606	Bos taurus	98.16	6.00e-170	589.00
IUUC-Cja-019482	Callithrix jacchus	98.09	5.00e-179	619.00
IUUC-Cfa-020482	Canis familiaris	99.39	2.00e-171	594.00
IUUC-Cpo-022061	Cavia porcellus	98.09	4.00e-179	620.00
IUUC-Csa-024102	Chlorocebus sabaeus	98.41	1.00e-180	625.00
IUUC-Cho-025081	Choloepus hoffmanni	81.12	5.00e-112	396.00
IUUC-Cin-025612	Ciona intestinalis	49.07	3.00e-52	199.00
IUUC-Dre-027929	Danio rerio	79.14	1.00e-141	495.00
IUUC-Dno-029797	Dasypus novemcinctus	97.45	0.00e+00	641.00
IUUC-Dor-030256	Dipodomys ordii	95.86	8.00e-168	582.00
IUUC-Dme-031904	Drosophila melanogaster	44.74	3.00e-53	204.00
IUUC-Ete-033148	Echinops telfairi	64.71	6.00e-83	300.00
IUUC-Eca-033318	Equus caballus	98.77	1.00e-170	591.00
IUUC-Eeu-034547	Erinaceus europaeus	84.71	5.00e-148	516.00
IUUC-Fca-035866	Felis catus	98.77	4.00e-170	590.00
IUUC-Fal-036660	Ficedula albicollis	95.09	1.00e-159	555.00
IUUC-Gmo-039341	Gadus morhua	82.69	6.00e-126	443.00
IUUC-Gga-040611	Gallus gallus	94.90	5.00e-166	576.00
IUUC-Gac-041888	Gasterosteus aculeatus	72.19	6.00e-129	453.00
IUUC-Gma-042798	Glycine max	39.02	6.00e-12	65.50
IUUC-Ggo-045027	Gorilla gorilla	98.41	1.00e-179	621.00
IUUC-Hsa-045665	Homo sapiens	98.47	2.00e-180	624.00
IUUC-Itr-049045	Ictidomys tridecemlineatus	97.77	1.00e-176	612.00
IUUC-Lch-049714	Latimeria chalumnae	85.93	1.00e-163	568.00
IUUC-Loc-052161	Lepisosteus oculatus	81.04	6.00e-144	503.00
IUUC-Laf-054108	Loxodonta africana	96.36	8.00e-177	612.00
IUUC-Mcc-055562	Macaca mulatta	98.47	2.00e-180	625.00
IUUC-Meu-056709	Macropus eugenii	96.93	2.00e-172	597.00
IUUC-Mtr-058158	Medicago truncatula	43.42	4.00e-10	57.40
IUUC-Mga-060104	Meleagris gallopavo	91.97	5.00e-120	423.00
IUUC-Mmr-061191	Microcebus murinus	98.47	2.00e-180	625.00
IUUC-Mdo-062711	Monodelphis domestica	92.09	1.00e-152	532.00
IUUC-Mmu-064255	Mus musculus	94.90	5.00e-166	576.00
IUUC-Mlu-067622	Myotis lucifugus	97.77	2.00e-178	617.00
IUUC-Nle-069253	Nomascus leucogenys	98.41	2.00e-180	625.00
IUUC-Opr-070511	Ochotona princeps	97.77	1.00e-177	615.00
IUUC-Ont-072177	Oreochromis niloticus	83.85	3.00e-129	454.00
IUUC-Oan-073336	Ornithorhynchus anatinus	96.63	7.00e-170	589.00
IUUC-Ocu-074113	Oryctolagus cuniculus	97.77	7.00e-169	586.00
IUUC-Ogl-077513	Oryza glaberrima	42.25	9.00e-12	65.10
IUUC-Oni-082398	Oryza nivara	42.25	9.00e-12	65.10
IUUC-Oru-084965	Oryza rufipogon	42.25	9.00e-12	65.10
IUUC-Ola-087057	Oryzias latipes	85.19	8.00e-124	436.00
IUUC-Oga-088346	Otolemur garnettii	98.41	1.00e-179	621.00
IUUC-Oar-089843	Ovis aries	98.16	6.00e-170	589.00
IUUC-Ptr-090486	Pan troglodytes	98.41	1.00e-179	621.00
IUUC-Pan-092667	Papio anubis	98.86	3.00e-159	554.00
IUUC-Psi-093469	Pelodiscus sinensis	94.48	1.00e-171	595.00
IUUC-Pma-094481	Petromyzon marinus	74.04	1.00e-89	322.00
IUUC-Pfo-097156	Poecilia formosa	79.73	3.00e-133	467.00
IUUC-Pab-097670	Pongo abelii	98.41	1.00e-179	621.00
IUUC-Pop-099100	Populus trichocarpa	37.65	1.00e-12	67.40
IUUC-Pva-102800	Pteropus vampyrus	98.41	1.00e-179	621.00
IUUC-Rno-105128	Rattus norvegicus	94.59	4.00e-170	590.00
IUUC-Sha-106747	Sarcophilus harrisii	96.93	7.00e-162	562.00
IUUC-Sar-113416	Sorex araneus	98.09	4.00e-179	620.00
IUUC-Ssc-115864	Sus scrofa	98.41	9.00e-180	622.00
IUUC-Tgu-116851	Taeniopygia guttata	94.10	4.00e-135	473.00
IUUC-Tru-117698	Takifugu rubripes	85.77	4.00e-124	437.00
IUUC-Tsy-119590	Tarsius syrichta	97.77	2.00e-178	617.00
IUUC-Tni-120170	Tetraodon nigroviridis	83.46	2.00e-128	451.00
IUUC-Tae-123760	Triticum aestivum	37.21	6.00e-12	65.50
IUUC-Tur-126396	Triticum urartu	37.21	6.00e-12	65.10
IUUC-Tbe-127790	Tupaia belangeri	98.09	4.00e-179	620.00
IUUC-Ttr-129316	Tursiops truncatus	98.47	5.00e-179	619.00
IUUC-Vpa-130669	Vicugna pacos	98.77	1.00e-170	591.00
IUUC-Xtr-131912	Xenopus tropicalis	87.16	1.00e-147	515.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence