iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Itr-048187

Ensembl Protein ID

ENSSTOP00000020050.1

UniProt Accession

I3N6Q4; I3N6Q4_ICTTR

Genbank Protein ID

ENSSTOP00000020050

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGTP01042258

Gene Name

USP54

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSTOG00000026728.1	ENSSTOT00000027596.1	ENSSTOP00000020050.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	2.80e-24	85.9	32	349

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 2    GlkNl..gNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelwkskkkavspre.....llkalkkeaee 83
           Gl+N   +N+C++NS+LQ+L+++  +r+ + + +++k+  +       ++ ++l+ +f++++ +++++v p++     l k++++e+ +
   Q: 32   GLSNEpgQNSCFLNSALQVLWHLDIFRRSFRQLTTHKCMGD------SCIFCALKGIFNQFQ-CSSEKVLPSDtlrsaLAKTFQDEQ-R 112
           88887668******************************986......59************5.555555555543333555555444.5 PP
   S: 84   fsgyeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldl 172
           f+     Da E+++ ll +++ ++                    de +e+  + ++++ ++ F ++l +q++c +c+ +s    pf+++
   Q: 113  FQLGIMDDAAECFENLLMRIHFHI-------------------ADETKEDICTAQHCISHQKFAMTLFEQCVCTSCGATSDPL-PFIQM 181
           99**********************...................3455677899*************************99766.9**** PP
   S: 173  slpvpgkeetkke.........slqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkk 252
              ++  + +++             +++ +  ++ +  g+ +   ++c ++ +  +++   + P+++++ L +   s + +  e +  +
   Q: 182  VHYISTTSLCNQAicmlerrekPSPSMFGELLQNASTMGDLRNCPSNCGERIR-IRRVL-MNAPQIITIGLVWD--SDHSDLAEDVIHS 266
           *****999988889999999985556666666677777666667777777664.56655.566**********9..3333444444444 PP
   S: 253  vefpleLdlsp..fctspeekqkekkkYeLiavvvHsGslssGHYvayvknekgk.WllfdDskVtev..keeevleetg...staYvl 333
           + +   L+l    f ++ ++  k+++ Y L+++++++G     HY ++  ++k + W++fdD +V+e+  k+++v++++     ++ +l
   Q: 267  LGTC--LKLGDlfFRVT-DDRAKQSELY-LVGMICYYG----KHYSTFFFQTKIRkWMYFDDAHVKEIgpKWKDVVTKCIkghYQPLLL 347
           4444..55555213333.3333335555.*********....9*****99987767************766899988655555555566 PP
   S: 334  fY 335
           +Y
   Q: 348  LY 349
           66 PP

Organism

Ictidomys tridecemlineatus

Protein Sequence
(Fasta)

MSWKRNYFSG GRGSVQGMFA PRSSTSIAPS KGLSNEPGQN SCFLNSALQV LWHLDIFRRS 60
FRQLTTHKCM GDSCIFCALK GIFNQFQCSS EKVLPSDTLR SALAKTFQDE QRFQLGIMDD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTTAAGCTAA ATGTGAACAG TTATGTCTTG GAAAAGAAAT TATTTTTCAG GGGGCCGTGG 60
CAGTGTCCAA GGGATGTTTG CACCTCGAAG CTCAACCTCC ATAGCCCCCA GCAAAGGCCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR028889--USP_dom

PROSITE

PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000820	Aegilops tauschii	32.20	1.00e-18	87.40
IUUC-Aml-001414	Ailuropoda melanoleuca	75.69	0.00e+00	1590.00
IUUC-Apl-004044	Anas platyrhynchos	69.81	0.00e+00	1075.00
IUUC-Aca-004351	Anolis carolinensis	94.76	0.00e+00	790.00
IUUC-Aly-005468	Arabidopsis lyrata	32.78	2.00e-43	171.00
IUUC-Ath-006682	Arabidopsis thaliana	32.49	1.00e-42	168.00
IUUC-Ame-011525	Astyanax mexicanus	84.03	0.00e+00	717.00
IUUC-Bta-013344	Bos taurus	75.68	0.00e+00	2301.00
IUUC-Bdi-015058	Brachypodium distachyon	32.13	3.00e-41	164.00
IUUC-Bol-015670	Brassica oleracea	31.27	1.00e-39	158.00
IUUC-Bra-016731	Brassica rapa	32.36	5.00e-42	167.00
IUUC-Cja-018724	Callithrix jacchus	73.78	0.00e+00	1507.00
IUUC-Cfa-021222	Canis familiaris	75.06	0.00e+00	1637.00
IUUC-Cpo-021795	Cavia porcellus	77.30	0.00e+00	1236.00
IUUC-Cre-022697	Chlamydomonas reinhardtii	23.80	2.00e-17	86.30
IUUC-Csa-023262	Chlorocebus sabaeus	73.82	0.00e+00	1516.00
IUUC-Cho-024422	Choloepus hoffmanni	75.90	0.00e+00	1849.00
IUUC-Cin-025752	Ciona intestinalis	68.60	6.00e-48	182.00
IUUC-Csv-026063	Ciona savignyi	56.10	5.00e-112	397.00
IUUC-Dre-028802	Danio rerio	63.14	0.00e+00	818.00
IUUC-Dno-029417	Dasypus novemcinctus	74.78	0.00e+00	1558.00
IUUC-Dor-030653	Dipodomys ordii	69.44	0.00e+00	956.00
IUUC-Dme-032071	Drosophila melanogaster	53.82	2.00e-104	374.00
IUUC-Ete-032692	Echinops telfairi	59.92	0.00e+00	693.00
IUUC-Eca-033235	Equus caballus	77.77	0.00e+00	1298.00
IUUC-Eeu-034975	Erinaceus europaeus	66.41	0.00e+00	776.00
IUUC-Fca-036070	Felis catus	75.83	0.00e+00	1613.00
IUUC-Fal-037089	Ficedula albicollis	52.34	0.00e+00	1382.00
IUUC-Gmo-038653	Gadus morhua	75.46	1.00e-172	598.00
IUUC-Gga-041241	Gallus gallus	94.24	0.00e+00	793.00
IUUC-Gac-042157	Gasterosteus aculeatus	59.57	0.00e+00	865.00
IUUC-Gma-043273	Glycine max	31.20	1.00e-37	152.00
IUUC-Ggo-045626	Gorilla gorilla	73.56	0.00e+00	1528.00
IUUC-Hsa-045767	Homo sapiens	73.95	0.00e+00	1533.00
IUUC-Hvu-047657	Hordeum vulgare	31.39	4.00e-42	167.00
IUUC-Lch-049712	Latimeria chalumnae	88.22	0.00e+00	714.00
IUUC-Lpe-051572	Leersia perrieri	32.05	5.00e-39	157.00
IUUC-Loc-052615	Lepisosteus oculatus	60.81	0.00e+00	905.00
IUUC-Laf-054578	Loxodonta africana	80.83	0.00e+00	2313.00
IUUC-Mcc-054696	Macaca mulatta	73.90	0.00e+00	1519.00
IUUC-Meu-056841	Macropus eugenii	45.28	9.00e-157	548.00
IUUC-Mga-059519	Meleagris gallopavo	45.01	0.00e+00	676.00
IUUC-Mmr-060701	Microcebus murinus	73.80	0.00e+00	1492.00
IUUC-Mdo-062433	Monodelphis domestica	53.88	0.00e+00	975.00
IUUC-Mmu-063480	Mus musculus	77.72	0.00e+00	2236.00
IUUC-Mpu-066404	Mustela putorius furo	74.00	0.00e+00	1657.00
IUUC-Mlu-067841	Myotis lucifugus	82.15	0.00e+00	2319.00
IUUC-Nle-070110	Nomascus leucogenys	77.98	0.00e+00	1247.00
IUUC-Opr-070676	Ochotona princeps	77.07	0.00e+00	777.00
IUUC-Ont-072289	Oreochromis niloticus	82.44	0.00e+00	680.00
IUUC-Oan-073551	Ornithorhynchus anatinus	58.90	0.00e+00	1454.00
IUUC-Ocu-074729	Oryctolagus cuniculus	74.49	0.00e+00	1575.00
IUUC-Obr-076268	Oryza brachyantha	33.24	2.00e-42	168.00
IUUC-Ogl-077138	Oryza glaberrima	32.35	2.00e-39	158.00
IUUC-Oin-079125	Oryza indica	32.35	2.00e-39	158.00
IUUC-Opu-083823	Oryza punctata	32.94	4.00e-40	160.00
IUUC-Ola-086742	Oryzias latipes	60.69	0.00e+00	788.00
IUUC-Oga-088920	Otolemur garnettii	78.89	0.00e+00	1273.00
IUUC-Oar-089644	Ovis aries	75.79	0.00e+00	2311.00
IUUC-Ptr-091530	Pan troglodytes	77.26	0.00e+00	1231.00
IUUC-Pan-092190	Papio anubis	99.48	0.00e+00	819.00
IUUC-Psi-094022	Pelodiscus sinensis	94.24	0.00e+00	790.00
IUUC-Pma-094745	Petromyzon marinus	59.89	1.00e-134	472.00
IUUC-Pfo-096072	Poecilia formosa	82.19	0.00e+00	685.00
IUUC-Pab-097979	Pongo abelii	77.52	0.00e+00	1161.00
IUUC-Pop-099539	Populus trichocarpa	31.69	1.00e-37	152.00
IUUC-Pca-101005	Procavia capensis	64.65	0.00e+00	1221.00
IUUC-Ppe-101918	Prunus persica	30.90	7.00e-39	156.00
IUUC-Pva-103125	Pteropus vampyrus	74.47	0.00e+00	1544.00
IUUC-Rno-105463	Rattus norvegicus	70.02	0.00e+00	1425.00
IUUC-Sha-107164	Sarcophilus harrisii	53.25	0.00e+00	911.00
IUUC-Sit-110021	Setaria italica	32.26	1.00e-37	152.00
IUUC-Sly-110975	Solanum lycopersicum	31.21	2.00e-39	158.00
IUUC-Stu-112904	Solanum tuberosum	31.40	1.00e-37	152.00
IUUC-Sar-113423	Sorex araneus	57.73	0.00e+00	777.00
IUUC-Sbi-114345	Sorghum bicolor	32.84	2.00e-41	164.00
IUUC-Ssc-116206	Sus scrofa	75.71	0.00e+00	2205.00
IUUC-Tgu-116521	Taeniopygia guttata	78.85	0.00e+00	1313.00
IUUC-Tru-118155	Takifugu rubripes	70.20	4.00e-172	597.00
IUUC-Tsy-118998	Tarsius syrichta	74.63	0.00e+00	1407.00
IUUC-Tni-120257	Tetraodon nigroviridis	80.36	0.00e+00	663.00
IUUC-Tca-121692	Theobroma cacao	31.87	1.00e-38	155.00
IUUC-Tae-125619	Triticum aestivum	31.67	6.00e-43	169.00
IUUC-Tur-126027	Triticum urartu	31.20	1.00e-42	169.00
IUUC-Tbe-128072	Tupaia belangeri	65.91	4.00e-145	508.00
IUUC-Ttr-128290	Tursiops truncatus	78.53	0.00e+00	1182.00
IUUC-Vpa-130213	Vicugna pacos	73.49	0.00e+00	1205.00
IUUC-Vvi-131652	Vitis vinifera	31.20	6.00e-39	156.00
IUUC-Xtr-131831	Xenopus tropicalis	64.48	0.00e+00	1101.00
IUUC-Xma-133456	Xiphophorus maculatus	79.13	0.00e+00	657.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence