iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Fca-035491

Ensembl Protein ID

ENSFCAP00000019752.1

UniProt Accession

M3WZG1; M3WZG1_FELCA

Genbank Protein ID

ENSFCAP00000019752

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AANG02169656

Gene Name

TSG101

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSFCAG00000028742.1	ENSFCAT00000024585.1	ENSFCAP00000019752.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/UBC-like/UBD_UEV	6.70e-68	227.0	2	145

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/UBC-like/UBD_UEV

   S: 1    AvsesslkkvpskykdkrltvrellnliesykslkpktasfvlnDgesreLlrltGtipvpergitynipiilwlletYPekPPfvsvk 89
           Avses+lkk++skyk+++ltvre++n+i+ yk+lkp+++s+v+nDg+sreL++ltGtipvp++g++ynipi+lwll+tYP++PP+++vk
   Q: 2    AVSESQLKKMVSKYKYRDLTVRETVNVITLYKDLKPVLDSYVFNDGSSRELMNLTGTIPVPYKGNIYNIPICLWLLDTYPYNPPICFVK 90
           89*************************************************************************************** PP
   S: 90   ekidmntikssnehvdpnGkialpvLhkWknpasnlvelvqelivllskeppklsrp 146
           ++++m tik++ +hvd+nGki+lp+Lh+Wk+p+s+l+ l+q++iv++++epp++srp
   Q: 91   PTSSM-TIKTG-KHVDANGKIYLPYLHEWKHPQSDLLGLIQVMIVVFGDEPPVFSRP 145
           *****.*****.*******************************************98 PP

Organism

Felis catus

Protein Sequence
(Fasta)

MAVSESQLKK MVSKYKYRDL TVRETVNVIT LYKDLKPVLD SYVFNDGSSR ELMNLTGTIP 60
VPYKGNIYNI PICLWLLDTY PYNPPICFVK PTSSMTIKTG KHVDANGKIY LPYLHEWKHP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGGGGTGGGG GGCTGGCTAC TAGGTGTGTG ATTGTGTGGG GCGGCCTGGG GCGGCCCCGG 60
AGCGGCTGAC CCTCTGCCTG CGGGGACGGG AGTCGCCAGG CGGCCGCCAT GGCGGTGTCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR017916--SB_dom
IPR016135--UBQ-conjugating_enzyme/RWD
IPR008883--UEV_N

PROSITE

PS51312--SB
PS51322--UEV

Pfam

PF05743--UEV
PF09454--Vps23_core

Gene Ontology

GO:0005829--C:cytosol
GO:0005769--C:early endosome
GO:0000813--C:ESCRT I complex
GO:0070062--C:extracellular exosome
GO:0005770--C:late endosome
GO:0005730--C:nucleolus
GO:0005886--C:plasma membrane
GO:0003714--F:transcription corepressor activity
GO:0046790--F:virion binding
GO:0007050--P:cell cycle arrest
GO:0006464--P:cellular protein modification process
GO:1990182--P:exosomal secretion
GO:0030216--P:keratinocyte differentiation
GO:0008285--P:negative regulation of cell proliferation
GO:0042059--P:negative regulation of epidermal growth factor receptor signaling pathway
GO:0045892--P:negative regulation of transcription, DNA-templated
GO:1903543--P:positive regulation of exosomal secretion
GO:2000397--P:positive regulation of ubiquitin-dependent endocytosis
GO:1903774--P:positive regulation of viral budding via host ESCRT complex
GO:1902188--P:positive regulation of viral release from host cell
GO:0015031--P:protein transport
GO:0001558--P:regulation of cell growth
GO:1903551--P:regulation of extracellular exosome assembly
GO:0043405--P:regulation of MAP kinase activity
GO:0043162--P:ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway
GO:0046755--P:viral budding

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-001072	Aegilops tauschii	37.19	2.00e-20	93.60
IUUC-Aml-002415	Ailuropoda melanoleuca	98.72	0.00e+00	736.00
IUUC-Atr-002875	Amborella trichopoda	29.12	1.00e-35	144.00
IUUC-Apl-003473	Anas platyrhynchos	86.99	0.00e+00	674.00
IUUC-Aca-004573	Anolis carolinensis	89.29	0.00e+00	665.00
IUUC-Aly-006164	Arabidopsis lyrata	43.14	2.00e-21	96.30
IUUC-Ath-006575	Arabidopsis thaliana	43.14	2.00e-21	96.70
IUUC-Ago-007755	Ashbya gossypii	25.00	2.00e-05	43.50
IUUC-Acl-008218	Aspergillus clavatus	37.98	2.00e-25	110.00
IUUC-Afl-008597	Aspergillus flavus	38.35	2.00e-25	110.00
IUUC-Afu-009017	Aspergillus fumigatus	37.21	2.00e-23	103.00
IUUC-Ani-009468	Aspergillus nidulans	37.88	3.00e-21	96.70
IUUC-Ang-009755	Aspergillus niger	35.71	1.00e-22	101.00
IUUC-Aor-010072	Aspergillus oryzae	36.84	1.00e-25	110.00
IUUC-Ate-010400	Aspergillus terreus	37.98	4.00e-25	109.00
IUUC-Ame-011620	Astyanax mexicanus	79.49	0.00e+00	640.00
IUUC-Bgr-012136	Blumeria graminis	34.31	8.00e-23	101.00
IUUC-Bta-012557	Bos taurus	96.93	0.00e+00	717.00
IUUC-Bci-013881	Botrytis cinerea	35.29	3.00e-25	109.00
IUUC-Bdi-014325	Brachypodium distachyon	32.11	3.00e-14	72.80
IUUC-Bol-016308	Brassica oleracea	40.80	3.00e-26	113.00
IUUC-Bra-017605	Brassica rapa	40.32	3.00e-26	112.00
IUUC-Cel-018697	Caenorhabditis elegans	49.61	1.00e-37	150.00
IUUC-Cja-018963	Callithrix jacchus	90.31	0.00e+00	713.00
IUUC-Cfa-020472	Canis familiaris	98.72	0.00e+00	735.00
IUUC-Cpo-022001	Cavia porcellus	97.95	0.00e+00	731.00
IUUC-Cre-022918	Chlamydomonas reinhardtii	30.11	9.00e-32	131.00
IUUC-Csa-023959	Chlorocebus sabaeus	97.44	0.00e+00	697.00
IUUC-Cho-024389	Choloepus hoffmanni	55.45	8.00e-38	151.00
IUUC-Cin-025688	Ciona intestinalis	44.53	9.00e-99	353.00
IUUC-Cne-026904	Cryptococcus neoformans	29.19	2.00e-14	74.30
IUUC-Cme-027280	Cyanidioschyzon merolae	38.18	3.00e-17	82.40
IUUC-Dre-027913	Danio rerio	79.49	9.00e-176	609.00
IUUC-Dno-029672	Dasypus novemcinctus	96.42	0.00e+00	736.00
IUUC-Dor-030175	Dipodomys ordii	96.00	2.00e-92	332.00
IUUC-Dse-031375	Dothistroma septosporum	31.39	3.00e-22	99.80
IUUC-Dme-031736	Drosophila melanogaster	49.26	8.00e-96	343.00
IUUC-Ete-032343	Echinops telfairi	91.30	0.00e+00	691.00
IUUC-Eca-033926	Equus caballus	97.95	0.00e+00	727.00
IUUC-Eeu-034940	Erinaceus europaeus	90.28	0.00e+00	717.00
IUUC-Fal-037508	Ficedula albicollis	89.80	0.00e+00	670.00
IUUC-Fox-037937	Fusarium oxysporum	30.77	2.00e-20	93.60
IUUC-Fso-038091	Fusarium solani	34.56	4.00e-24	105.00
IUUC-Gmo-039427	Gadus morhua	77.63	5.00e-172	597.00
IUUC-Ggr-039724	Gaeumannomyces graminis	35.82	4.00e-24	106.00
IUUC-Gga-040998	Gallus gallus	87.47	0.00e+00	696.00
IUUC-Gac-041356	Gasterosteus aculeatus	79.95	0.00e+00	639.00
IUUC-Gma-043566	Glycine max	38.89	8.00e-25	107.00
IUUC-Ggo-044967	Gorilla gorilla	97.44	0.00e+00	697.00
IUUC-Hsa-046686	Homo sapiens	97.44	0.00e+00	697.00
IUUC-Hvu-047430	Hordeum vulgare	37.19	1.00e-20	94.00
IUUC-Itr-047929	Ictidomys tridecemlineatus	97.77	2.00e-109	387.00
IUUC-Kpa-049287	Komagataella pastoris	30.25	4.00e-15	75.50
IUUC-Lch-050597	Latimeria chalumnae	85.97	0.00e+00	673.00
IUUC-Lpe-051090	Leersia perrieri	38.02	3.00e-20	92.80
IUUC-Loc-052399	Lepisosteus oculatus	80.05	5.00e-178	616.00
IUUC-Lma-053249	Leptosphaeria maculans	28.07	9.00e-13	68.60
IUUC-Laf-053766	Loxodonta africana	97.19	0.00e+00	728.00
IUUC-Mcc-055641	Macaca mulatta	97.44	0.00e+00	697.00
IUUC-Meu-055919	Macropus eugenii	89.57	1.00e-169	588.00
IUUC-Mor-056970	Magnaporthe oryzae	36.92	3.00e-23	103.00
IUUC-Mpo-057345	Magnaporthe poae	35.38	6.00e-22	98.60
IUUC-Mtr-058436	Medicago truncatula	37.30	2.00e-25	109.00
IUUC-Mla-059037	Melampsora laricipopulina	35.17	4.00e-25	109.00
IUUC-Mga-059263	Meleagris gallopavo	87.01	0.00e+00	670.00
IUUC-Mvi-060463	Microbotryum violaceum	30.32	6.00e-17	82.40
IUUC-Mmr-060915	Microcebus murinus	97.19	0.00e+00	723.00
IUUC-Mdo-062449	Monodelphis domestica	93.35	0.00e+00	689.00
IUUC-Mmu-063151	Mus musculus	94.12	0.00e+00	699.00
IUUC-Mac-065020	Musa acuminata	35.48	2.00e-22	100.00
IUUC-Mpu-066621	Mustela putorius furo	98.72	0.00e+00	736.00
IUUC-Mlu-067336	Myotis lucifugus	96.68	0.00e+00	704.00
IUUC-Nfi-068530	Neosartorya fischeri	37.98	2.00e-23	103.00
IUUC-Ncr-068785	Neurospora crassa	34.56	1.00e-23	104.00
IUUC-Nle-069972	Nomascus leucogenys	97.44	0.00e+00	697.00
IUUC-Opr-071150	Ochotona princeps	67.77	1.00e-122	432.00
IUUC-Ont-071366	Oreochromis niloticus	81.54	0.00e+00	640.00
IUUC-Oan-073290	Ornithorhynchus anatinus	92.17	3.00e-103	367.00
IUUC-Ocu-074351	Oryctolagus cuniculus	98.21	0.00e+00	732.00
IUUC-Oba-075338	Oryza barthii	37.14	2.00e-11	62.40
IUUC-Obr-076135	Oryza brachyantha	26.43	9.00e-29	120.00
IUUC-Ogl-077182	Oryza glaberrima	36.84	5.00e-17	82.00
IUUC-Ogu-078281	Oryza glumaepatula	27.81	1.00e-27	117.00
IUUC-Oin-079068	Oryza indica	36.28	1.00e-16	81.30
IUUC-Olo-080460	Oryza longistaminata	35.80	1.00e-08	52.80
IUUC-Ome-081781	Oryza meridionalis	27.05	6.00e-25	108.00
IUUC-Oni-082517	Oryza nivara	26.76	1.00e-23	103.00
IUUC-Opu-084101	Oryza punctata	36.84	4.00e-17	82.00
IUUC-Oru-084556	Oryza rufipogon	36.84	5.00e-17	82.00
IUUC-Osa-086264	Oryza sativa	36.28	5.00e-17	82.00
IUUC-Ola-087252	Oryzias latipes	92.62	4.00e-69	253.00
IUUC-Olu-087610	Ostreococcus lucimarinus	27.17	3.00e-13	69.30
IUUC-Oga-088304	Otolemur garnettii	96.93	0.00e+00	721.00
IUUC-Oar-089734	Ovis aries	96.93	0.00e+00	717.00
IUUC-Ptr-091476	Pan troglodytes	97.44	0.00e+00	697.00
IUUC-Pan-092341	Papio anubis	97.44	0.00e+00	697.00
IUUC-Psi-093470	Pelodiscus sinensis	91.43	0.00e+00	665.00
IUUC-Pma-094143	Petromyzon marinus	64.36	1.00e-134	472.00
IUUC-Pno-095069	Phaeosphaeria nodorum	30.25	1.00e-13	71.20
IUUC-Ppa-095933	Physcomitrella patens	29.40	6.00e-36	144.00
IUUC-Pfo-096321	Poecilia formosa	79.74	5.00e-176	610.00
IUUC-Pab-098527	Pongo abelii	96.60	3.00e-178	617.00
IUUC-Pop-099323	Populus trichocarpa	27.35	2.00e-36	146.00
IUUC-Pca-101044	Procavia capensis	78.77	1.00e-157	548.00
IUUC-Ppe-101458	Prunus persica	40.83	1.00e-26	113.00
IUUC-Pva-103014	Pteropus vampyrus	87.47	2.00e-173	601.00
IUUC-Pgr-103615	Puccinia graminis	35.34	1.00e-19	91.70
IUUC-Ptt-103826	Puccinia triticina	39.22	7.00e-16	78.60
IUUC-Pte-104171	Pyrenophora teres	33.82	1.00e-20	94.70
IUUC-Pyt-104433	Pyrenophora triticirepentis	31.45	3.00e-10	60.10
IUUC-Rno-105957	Rattus norvegicus	93.35	0.00e+00	694.00
IUUC-Sce-106262	Saccharomyces cerevisiae	26.12	3.00e-10	59.30
IUUC-Sha-107607	Sarcophilus harrisii	93.41	7.00e-173	599.00
IUUC-Spo-108175	Schizosaccharomyces pombe	30.56	1.50e-02	34.30
IUUC-Ssl-108672	Sclerotinia sclerotiorum	35.29	1.00e-25	110.00
IUUC-Smo-108973	Selaginella moellendorffii	39.47	7.00e-21	94.70
IUUC-Sly-111373	Solanum lycopersicum	35.71	5.00e-23	102.00
IUUC-Stu-112844	Solanum tuberosum	35.71	1.00e-22	100.00
IUUC-Sar-113653	Sorex araneus	84.58	3.00e-175	607.00
IUUC-Sbi-114390	Sorghum bicolor	35.54	5.00e-20	92.00
IUUC-Sre-115200	Sporisorium reilianum	36.18	2.00e-23	103.00
IUUC-Ssc-115888	Sus scrofa	98.24	4.00e-112	396.00
IUUC-Tgu-117506	Taeniopygia guttata	83.17	0.00e+00	678.00
IUUC-Tru-118063	Takifugu rubripes	78.77	5.00e-172	597.00
IUUC-Tsy-118851	Tarsius syrichta	73.85	6.00e-144	503.00
IUUC-Tni-120010	Tetraodon nigroviridis	79.08	5.00e-171	593.00
IUUC-Tca-121182	Theobroma cacao	38.10	8.00e-22	97.80
IUUC-Tre-122040	Trichoderma reesei	34.62	6.00e-21	95.50
IUUC-Tvi-122660	Trichoderma virens	38.24	5.00e-25	108.00
IUUC-Tae-124561	Triticum aestivum	37.19	2.00e-20	93.60
IUUC-Tur-126651	Triticum urartu	38.26	3.00e-20	92.00
IUUC-Tme-127184	Tuber melanosporum	45.54	6.00e-25	108.00
IUUC-Tbe-127894	Tupaia belangeri	82.00	2.00e-89	322.00
IUUC-Ttr-128264	Tursiops truncatus	89.00	0.00e+00	704.00
IUUC-Uma-129407	Ustilago maydis	34.87	9.00e-24	105.00
IUUC-Vda-130002	Verticillium dahliae	29.05	2.00e-15	77.40
IUUC-Vpa-130156	Vicugna pacos	96.00	6.00e-97	347.00
IUUC-Vvi-131062	Vitis vinifera	29.13	2.00e-31	129.00
IUUC-Xtr-132332	Xenopus tropicalis	81.68	1.00e-63	234.00
IUUC-Xma-133186	Xiphophorus maculatus	78.50	1.00e-176	612.00
IUUC-Yli-134500	Yarrowia lipolytica	33.55	1.00e-12	67.00
IUUC-Zma-135391	Zea mays	36.13	1.00e-19	90.90

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence