iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Cin-025540

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

EAAA01000951

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCING00000003077.3	ENSCINT00000006254.3	ENSCINP00000006254.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/Cullin	2.40e-85	287.3	1	255

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/Cullin

   S: 358  qlLrks..skglteeeleaqldkvllvfkyisekdvFekyYkkhLakRLlsgksasseaEesviekLkeec.gaeftskLerMfqdlkv 443
           +lLrk+  sk+l +ee++a+l++vllv+ky+s+kdvF++y+k hL++RL++g+sa+se+Ee+++e L+e++ +a+f++kL+rMfqd+kv
   Q: 1    MLLRKTplSKKLSSEEVDAKLKDVLLVLKYVSNKDVFMRYHKAHLTRRLILGTSADSEKEENMVEGLREVGmPADFVNKLARMFQDIKV 89
           689************************************************************************************** PP
   S: 444  SedlnrqFkeekenteesesvelsvlvLsagaWptasetekvsLPaelektiekfeefYlekhsgRkLqWqhtlgraelkaelkkgkye 532
           Sedln+qFk   e+ e+  s   ++++L+agaW++ s++  vsLPa le++i+++eefY++kh gR L+W h ++++ ++++ ++g y+
   Q: 90   SEDLNTQFK---EAREDRSSELANIKILNAGAWSRRSDRIPVSLPAILEDLIPDVEEFYKSKHHGRMLNWNHLMSNGVMTFKTEVGSYD 175
           *********...333334444569************99977************************************************ PP
   S: 533  lqVstfQmavLLafnns..ekvsveelkkatelpeeeLrrtlqsLvs.sk..kqvlkkepeske...ieeedlfsvNqef 604
           ++V+tfQm vL  +n +  e++s+e+l+ at+lp+ eLr+tl+sLv+ +k  +qvl  ep+ ++   ++e +++ vN++f
   Q: 176  IEVTTFQMSVLHIWNSRptESISFESLRLATQLPDTELRKTLWSLVAnPKlkRQVLLCEPKLSSpkeFQESSMLAVNHQF 255
           ****************999***************************9888999********977777***********99 PP

Organism

Ciona intestinalis

Protein Sequence
(Fasta)

MLLRKTPLSK KLSSEEVDAK LKDVLLVLKY VSNKDVFMRY HKAHLTRRLI LGTSADSEKE 60
ENMVEGLREV GMPADFVNKL ARMFQDIKVS EDLNTQFKEA REDRSSELAN IKILNAGAWS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTTCTTCTTT CTCTCTTCAA TCGTTTCTCG GACTTGGTGA AGAAGTCGTT CGATGATGAC 60
CCCAGGTTTT TAACGGCAAG GGACAAAGCG TTTGAATGTG TGGTGAATGA TTACTCAGTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR016157--Cullin_CS
IPR016158--Cullin_homology
IPR001373--Cullin_N
IPR019559--Cullin_neddylation_domain
IPR011991--WHTH_DNA-bd_dom

PROSITE

PS01256--CULLIN_1
PS50069--CULLIN_2

Pfam

PF00888--Cullin
PF10557--Cullin_Nedd8

SMART

SM00182--CULLIN
SM00884--Cullin_Nedd8

Gene Ontology

GO:0080008--C:Cul4-RING E3 ubiquitin ligase complex
GO:0031466--C:Cul5-RING ubiquitin ligase complex
GO:0031625--F:ubiquitin protein ligase binding
GO:0006974--P:cellular response to DNA damage stimulus
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002082	Ailuropoda melanoleuca	72.75	5.00e-150	523.00
IUUC-Apl-003564	Anas platyrhynchos	73.02	3.00e-150	524.00
IUUC-Aca-004319	Anolis carolinensis	73.02	3.00e-150	524.00
IUUC-Ame-011742	Astyanax mexicanus	72.75	1.00e-148	518.00
IUUC-Bta-012515	Bos taurus	73.02	1.00e-150	525.00
IUUC-Cel-018522	Caenorhabditis elegans	58.06	7.00e-119	419.00
IUUC-Cja-018785	Callithrix jacchus	73.02	2.00e-150	524.00
IUUC-Cfa-020932	Canis familiaris	73.02	2.00e-150	525.00
IUUC-Cpo-022317	Cavia porcellus	73.30	9.00e-151	526.00
IUUC-Csa-023949	Chlorocebus sabaeus	73.02	2.00e-150	524.00
IUUC-Csv-025978	Ciona savignyi	94.77	0.00e+00	677.00
IUUC-Dre-027958	Danio rerio	72.75	6.00e-153	533.00
IUUC-Dno-029195	Dasypus novemcinctus	73.02	2.00e-150	524.00
IUUC-Dor-030573	Dipodomys ordii	71.33	2.00e-117	414.00
IUUC-Dme-032083	Drosophila melanogaster	69.95	3.00e-154	537.00
IUUC-Ete-032428	Echinops telfairi	62.67	3.00e-118	417.00
IUUC-Eca-033232	Equus caballus	73.02	2.00e-150	524.00
IUUC-Eeu-035348	Erinaceus europaeus	73.02	2.00e-150	524.00
IUUC-Fca-035401	Felis catus	72.55	3.00e-146	510.00
IUUC-Fal-037514	Ficedula albicollis	73.02	3.00e-150	524.00
IUUC-Gmo-038577	Gadus morhua	72.36	3.00e-147	514.00
IUUC-Gga-041096	Gallus gallus	73.02	3.00e-150	524.00
IUUC-Gac-042108	Gasterosteus aculeatus	71.82	8.00e-147	513.00
IUUC-Ggo-045313	Gorilla gorilla	73.02	2.00e-150	525.00
IUUC-Hsa-045974	Homo sapiens	73.02	2.00e-150	524.00
IUUC-Itr-049009	Ictidomys tridecemlineatus	73.02	1.00e-149	522.00
IUUC-Lch-050615	Latimeria chalumnae	72.75	5.00e-149	520.00
IUUC-Loc-051807	Lepisosteus oculatus	73.30	5.00e-150	523.00
IUUC-Laf-053601	Loxodonta africana	73.02	2.00e-150	524.00
IUUC-Mcc-055260	Macaca mulatta	73.02	4.00e-150	523.00
IUUC-Mga-059658	Meleagris gallopavo	73.02	3.00e-150	524.00
IUUC-Mmr-061424	Microcebus murinus	73.02	4.00e-150	523.00
IUUC-Mdo-061836	Monodelphis domestica	73.02	6.00e-150	523.00
IUUC-Mmu-063757	Mus musculus	72.21	3.00e-148	518.00
IUUC-Mpu-065823	Mustela putorius furo	73.02	2.00e-150	524.00
IUUC-Mlu-066969	Myotis lucifugus	73.02	2.00e-150	524.00
IUUC-Nle-069943	Nomascus leucogenys	73.02	2.00e-150	524.00
IUUC-Opr-070820	Ochotona princeps	55.28	6.00e-61	227.00
IUUC-Ont-072527	Oreochromis niloticus	73.30	1.00e-149	521.00
IUUC-Oan-072743	Ornithorhynchus anatinus	73.02	2.00e-150	524.00
IUUC-Ocu-074586	Oryctolagus cuniculus	73.02	2.00e-150	524.00
IUUC-Ola-086712	Oryzias latipes	73.02	4.00e-153	533.00
IUUC-Oga-088425	Otolemur garnettii	70.42	8.00e-150	522.00
IUUC-Oar-089785	Ovis aries	73.02	2.00e-150	524.00
IUUC-Ptr-091242	Pan troglodytes	73.02	2.00e-150	524.00
IUUC-Pan-092246	Papio anubis	73.02	2.00e-150	524.00
IUUC-Psi-094081	Pelodiscus sinensis	73.02	3.00e-150	524.00
IUUC-Pfo-096357	Poecilia formosa	73.30	2.00e-150	525.00
IUUC-Pab-098248	Pongo abelii	73.02	2.00e-150	525.00
IUUC-Pca-100756	Procavia capensis	72.75	1.00e-147	515.00
IUUC-Pva-102990	Pteropus vampyrus	69.35	6.00e-50	191.00
IUUC-Rno-105887	Rattus norvegicus	72.75	5.00e-149	520.00
IUUC-Sha-107016	Sarcophilus harrisii	73.02	6.00e-150	523.00
IUUC-Sar-113558	Sorex araneus	72.30	4.00e-149	520.00
IUUC-Ssc-115414	Sus scrofa	73.02	2.00e-150	524.00
IUUC-Tgu-116801	Taeniopygia guttata	72.55	3.00e-148	517.00
IUUC-Tru-117565	Takifugu rubripes	73.57	2.00e-150	524.00
IUUC-Tsy-119292	Tarsius syrichta	72.21	5.00e-148	516.00
IUUC-Tni-120471	Tetraodon nigroviridis	73.57	4.00e-150	523.00
IUUC-Tbe-127838	Tupaia belangeri	72.30	3.00e-149	520.00
IUUC-Ttr-128345	Tursiops truncatus	73.02	3.00e-150	524.00
IUUC-Vpa-130191	Vicugna pacos	70.35	2.00e-84	305.00
IUUC-Xtr-132810	Xenopus tropicalis	73.30	2.00e-150	525.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence