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Tag Content
UUCD2 ID IUUC-Mdo-061836
UUCD1 version UUC-MoD-00771
Ensembl Protein ID ENSMODP00000018336.2
UniProt Accession F7E813; F7E813_MONDO
Protein Name Uncharacterized protein
Gene Name CUL5
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSMODG00000014666.3 ENSMODT00000018669.2 ENSMODP00000018336.2
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/Cullin 8.70e-230 764.7 22 672
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/Cullin
   S: 2    lreavkkilrqesv.kkeyeelytavynlclsk..vgaklYkklkevleefikqvkkkveesedeq.lLktynreWekfreqlkvlrki 86
           +r +v k+lrqesv k+++ +l+++v+++cl++  + ak++++lke++ +fikq++++v +++d++ lLk+y++eW+kf++q+++l+k+
   Q: 22   MRPIVLKLLRQESVtKQQWFDLFSDVHAVCLWDdkGPAKIHQALKEDILDFIKQAQARVLSHQDDTaLLKAYIVEWRKFFTQCDILPKP 110
           7899****************************9999***************************************************** PP
   S: 87   fayldrtyvkk.....skkv..sevrkLaldlwrkeivedikkrllelllklieaeRkgeavdrrllsgvveslveLslnk...laiyk 165
           f++l+ t ++k     +++v  s vrkL+ld+w+++i+++ik+rl+++++kl++aeR gea+d++l+ gv+es+v+L++n    l+iy+
   Q: 111  FCQLEITLMGKqgsnkKSNVedSIVRKLMLDTWNESIFSNIKNRLQDSAMKLVHAERLGEAFDSQLVIGVRESYVNLCSNPedkLQIYR 199
           ***********8765544448899*******************************************************99999***** PP
   S: 166  esFEakfleatqefykaesaeflqenevdeYlkkvearlneeeeraaryleestetk....Llevvekeliakhlesllaelvallrdk 250
           ++FE+++l++t++fy++++ ++lq+n+v++Y+k+++a+l+eee+ra ryle+++e++    L+e+++++l++++ e++lae++ +++++
   Q: 200  DNFEKAYLDSTERFYRTQAPSYLQQNGVQNYMKYADAKLKEEEKRALRYLETRRECNsveaLMECCVNALVTSFKETILAECQGMIKRN 288
           *******************************************************999999**************************** PP
   S: 251  ktedlsrmykLlsrvlngleellkeleshikeqgkaalt..aeekekdpkkyVerllelknklqklvseaFnndakFlkaldkafetfv 337
           +te+l++m++L+++v+ng+e++lk+le+hi ++g+a+++  ae++++d++kyVe+ll+l+n+++klv+eaF++d++Fl+a+dka++++v
   Q: 289  ETEKLHLMFSLMDKVPNGIEPMLKDLEEHIVSAGLADMVaaAETITTDSEKYVEQLLTLFNRFSKLVKEAFQDDPRFLTARDKAYKAVV 377
           **************************************99999********************************************** PP
   S: 338  nknsvlka................akspEllAryiDqlLrks..skglteeeleaqldkvllvfkyisekdvFekyYkkhLakRLlsgk 408
           n+++++k+                +k+pEllA+y+D+lLrk+  sk+lt+ee+ea+l++vllv+ky+++kdvF++y+k hL++RL++++
   Q: 378  NDATIFKLelplkqkgvglktqpeSKCPELLANYCDMLLRKTplSKKLTSEEIEAKLKEVLLVLKYVQNKDVFMRYHKAHLTRRLILDI 466
           ***************************************************************************************** PP
   S: 409  sasseaEesviekLkeec.gaeftskLerMfqdlkvSedlnrqFk.eekenteesesvelsvlvLsagaWptasetekvsLPaelekti 495
           sa+se+Ee+++e+L+e++ +a++++kL+rMfqd+kvSedln++Fk ++k+n+ + +++++++++L+agaW+++se++ vsLP+ele++i
   Q: 467  SADSEIEENMVEWLREVGmPADYVNKLARMFQDIKVSEDLNQAFKeMHKNNKLALPADSVNIKILNAGAWSRSSEKVFVSLPTELEDLI 555
           *********************************************5688888899********************************** PP
   S: 496  ekfeefYlekhsgRkLqWqhtlgraelkaelkkgkyelqVstfQmavLLafnns..ekvsveelkkatelpeeeLrrtlqsLvs.sk.. 579
           +++eefY+++hsgRkL+W+h ++++ +++++++g+y+l+V+tfQ+avL+a+n++  ek+s+e+lk atelp++eLrrtl+sLv+ +k  
   Q: 556  PEVEEFYKKNHSGRKLHWHHLMSNGIITFKNEVGQYDLEVTTFQLAVLFAWNQRprEKISFENLKLATELPDAELRRTLWSLVAfPKlk 644
           *****************************************************999****************************99999 PP
   S: 580  kqvlkkepes...keieeedlfsvNqef 604
           +qvl +ep+    k+++e++lfsvNqef
   Q: 645  RQVLLYEPQVispKDFTEGTLFSVNQEF 672
           9********954455************9 PP
   
Organism Monodelphis domestica
Protein Sequence
(Fasta)
MATSNLLKNK GSLQFEDKWD FMRPIVLKLL RQESVTKQQW FDLFSDVHAV CLWDDKGPAK 60
IHQALKEDIL DFIKQAQARV LSHQDDTALL KAYIVEWRKF FTQCDILPKP FCQLEITLMG 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Mdo-061836|E3,Cullin|Monodelphis domestica
Please wait for a moment...
Nucleotide Sequence
(Fasta)
AAGTTGAGGG AACATGGCGA CGTCTAATCT GTTAAAGGTA AGAACCTCAC TCCTGCCGTC 60
TCTCTTCGTC GGCTCCGGAT TCCACTACAG GGCCCGGGCC AGGGAAGTAG CACAACTTGG 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Mdo-061836|E3,Cullin|Monodelphis domestica
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
Interpro

IPR016157--Cullin_CS
IPR016158--Cullin_homology
IPR001373--Cullin_N
IPR019559--Cullin_neddylation_domain
IPR016159--Cullin_repeat-like_dom
IPR011991--WHTH_DNA-bd_dom
PROSITE

PS01256--CULLIN_1
PS50069--CULLIN_2
Pfam

PF00888--Cullin
PF10557--Cullin_Nedd8
SMART

SM00182--CULLIN
SM00884--Cullin_Nedd8
Gene Ontology

GO:0080008--C:Cul4-RING E3 ubiquitin ligase complex
GO:0031466--C:Cul5-RING ubiquitin ligase complex
GO:0031625--F:ubiquitin protein ligase binding
GO:0006974--P:cellular response to DNA damage stimulus
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process
KEGG mdo:100032484
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-002082 Ailuropoda melanoleuca 98.46 0.00e+00 1548.00
IUUC-Apl-003564 Anas platyrhynchos 99.74 0.00e+00 1552.00
IUUC-Aca-004319 Anolis carolinensis 99.49 0.00e+00 1565.00
IUUC-Ame-011742 Astyanax mexicanus 96.93 0.00e+00 1531.00
IUUC-Bta-012515 Bos taurus 99.60 0.00e+00 1522.00
IUUC-Cel-018522 Caenorhabditis elegans 51.35 0.00e+00 760.00
IUUC-Cja-018785 Callithrix jacchus 99.49 0.00e+00 1565.00
IUUC-Cfa-020932 Canis familiaris 99.47 0.00e+00 1520.00
IUUC-Cpo-022317 Cavia porcellus 99.49 0.00e+00 1567.00
IUUC-Csa-023949 Chlorocebus sabaeus 99.62 0.00e+00 1567.00
IUUC-Cho-024570 Choloepus hoffmanni 99.07 3.00e-127 448.00
IUUC-Cin-025540 Ciona intestinalis 73.02 2.00e-151 528.00
IUUC-Csv-025978 Ciona savignyi 65.19 0.00e+00 1008.00
IUUC-Dre-027958 Danio rerio 96.92 0.00e+00 1546.00
IUUC-Dno-029195 Dasypus novemcinctus 99.36 0.00e+00 1554.00
IUUC-Dor-030573 Dipodomys ordii 86.96 2.00e-172 598.00
IUUC-Dme-032083 Drosophila melanogaster 68.29 0.00e+00 922.00
IUUC-Ete-032428 Echinops telfairi 82.31 0.00e+00 1233.00
IUUC-Eca-033232 Equus caballus 99.49 0.00e+00 1565.00
IUUC-Eeu-035348 Erinaceus europaeus 99.74 0.00e+00 753.00
IUUC-Fca-035401 Felis catus 98.97 0.00e+00 1528.00
IUUC-Fal-037514 Ficedula albicollis 99.61 0.00e+00 1548.00
IUUC-Gmo-038577 Gadus morhua 94.25 0.00e+00 1496.00
IUUC-Gga-041096 Gallus gallus 99.48 0.00e+00 1552.00
IUUC-Gac-042108 Gasterosteus aculeatus 95.15 0.00e+00 1509.00
IUUC-Ggo-045313 Gorilla gorilla 99.10 0.00e+00 1559.00
IUUC-Hsa-045974 Homo sapiens 99.62 0.00e+00 1567.00
IUUC-Itr-049009 Ictidomys tridecemlineatus 99.62 0.00e+00 1565.00
IUUC-Lch-050615 Latimeria chalumnae 98.95 0.00e+00 1513.00
IUUC-Loc-051807 Lepisosteus oculatus 98.21 0.00e+00 1547.00
IUUC-Laf-053601 Loxodonta africana 99.48 0.00e+00 1555.00
IUUC-Mcc-055260 Macaca mulatta 99.62 0.00e+00 1566.00
IUUC-Meu-056632 Macropus eugenii 100.00 0.00e+00 959.00
IUUC-Mga-059658 Meleagris gallopavo 99.48 0.00e+00 1552.00
IUUC-Mmr-061424 Microcebus murinus 89.60 0.00e+00 1353.00
IUUC-Mmu-063757 Mus musculus 98.08 0.00e+00 1548.00
IUUC-Mpu-065823 Mustela putorius furo 99.62 0.00e+00 1566.00
IUUC-Mlu-066969 Myotis lucifugus 99.10 0.00e+00 1547.00
IUUC-Nle-069943 Nomascus leucogenys 99.62 0.00e+00 1567.00
IUUC-Opr-070820 Ochotona princeps 99.54 0.00e+00 866.00
IUUC-Ont-072527 Oreochromis niloticus 96.15 0.00e+00 1528.00
IUUC-Oan-072743 Ornithorhynchus anatinus 99.74 0.00e+00 1524.00
IUUC-Ocu-074586 Oryctolagus cuniculus 99.62 0.00e+00 1567.00
IUUC-Ola-087526 Oryzias latipes 96.28 0.00e+00 1528.00
IUUC-Oga-088425 Otolemur garnettii 94.97 0.00e+00 1514.00
IUUC-Oar-089785 Ovis aries 99.62 0.00e+00 1567.00
IUUC-Ptr-091242 Pan troglodytes 99.62 0.00e+00 1567.00
IUUC-Pan-092246 Papio anubis 99.62 0.00e+00 1567.00
IUUC-Psi-094081 Pelodiscus sinensis 99.74 0.00e+00 1557.00
IUUC-Pma-094735 Petromyzon marinus 82.26 0.00e+00 748.00
IUUC-Pfo-097305 Poecilia formosa 95.90 0.00e+00 1519.00
IUUC-Pab-098248 Pongo abelii 93.46 0.00e+00 1446.00
IUUC-Pca-100756 Procavia capensis 88.08 0.00e+00 872.00
IUUC-Pva-102990 Pteropus vampyrus 85.53 0.00e+00 917.00
IUUC-Rno-105887 Rattus norvegicus 98.33 0.00e+00 1548.00
IUUC-Sha-107016 Sarcophilus harrisii 100.00 0.00e+00 1573.00
IUUC-Sar-113558 Sorex araneus 93.78 0.00e+00 1481.00
IUUC-Ssc-115414 Sus scrofa 99.62 0.00e+00 1567.00
IUUC-Tgu-116801 Taeniopygia guttata 98.72 0.00e+00 1544.00
IUUC-Tru-117565 Takifugu rubripes 96.41 0.00e+00 1529.00
IUUC-Tsy-119292 Tarsius syrichta 93.61 0.00e+00 1370.00
IUUC-Tni-120471 Tetraodon nigroviridis 96.29 0.00e+00 1523.00
IUUC-Tbe-127838 Tupaia belangeri 93.85 0.00e+00 1497.00
IUUC-Ttr-128345 Tursiops truncatus 99.10 0.00e+00 1559.00
IUUC-Vpa-130191 Vicugna pacos 90.64 0.00e+00 854.00
IUUC-Xtr-132810 Xenopus tropicalis 98.97 0.00e+00 1556.00
Created Date 25-Jun-2017

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