iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Uma-129599

Ensembl Protein ID

KIS71870

UniProt Accession

A0A0D1EBZ2; A0A0D1EBZ2_USTMA

Genbank Protein ID

KIS71870.1

Protein Name

Ubiquitinyl hydrolase 1

Genbank Nucleotide ID

CM003140

Gene Name

UMAG_00298

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
UMAG_00298	KIS71870	KIS71870

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	4.20e-59	198.9	313	859
UBD/Alpha-Helix/UBA	7.80e-16	56.2	723	753

Active Site

Position(s)	Description	Evidence
322	Nucleophile	{ECO:0000256\|PIRSR:PIRSR016308-1}
808	Proton acceptor	{ECO:0000256\|PIRSR:PIRSR016308-1}

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle.kkkeklneenpkepkgellkslqklfeel................................wkskkkav 68
           tGl+NlgN+CYm SvLQ+ ++++ ++  + +   +++l+ +  + p +++ ++++kl   l                                ++  +k +
   Q: 313  TGLRNLGNSCYMASVLQSVFSLSAFKTRYGDaYRPHSLACT--NMPATCFECQITKLADGLlsgrysyprepdqsgsawihaagsadeqqqqqQSLFQKGI 411
           7*************************999995445555554..46888999999999999977777777777777777666666555543322244455** PP
   S: 69   sprellkalkkeaeefsgyeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvs.sreep 168
            p+++++ ++k +eefs+++qqDa Efl++l+  +++e  k                      ++  + +++  +++F++ l++++ c++c++v  s e +
   Q: 412  RPSMFKALVGKGHEEFSTMRQQDADEFLKYLVGVVQKENRK--------------------LASSGSSLHTDDPTTVFGFGLEQRLECNTCHKVRySVERQ 492
           *************************************9922....................234455667777899******************9777778 PP
   S: 169  fldlslpvpgkeetkke........................................slqdcLesftkeeelegenkyycekckkkqeaekklklkklPev 229
              lslpvp +++ +++                                        sl +cL+ ft++eele    y+c++c+ k++a+k++ ++++P+v
   Q: 493  DAGLSLPVPIRRKAAEQhvsagkrpveglgaaestvsnsesasasavcndaeeyepvSLVECLDLFTAPEELE----YNCPSCCTKVTATKRTLFSTFPDV 589
           88888888888877666889****************************************************9....************************ PP
   S: 230  LilhLkRfsfseeqksrekinkkvefple..Ldlspfcts..................................................peekqke.... 274
           L l+ +Rf  +  +++++k+  ++ +p+   Ldl++++ +                                                  +     +    
   Q: 590  LALQVQRF--QLLNWVPQKVAVRIVVPIDtpLDLDRYLGRgkqpheeelgedqsdsssanggepewdvgvlsqltsmgfaeirckkavlaT-----Rmgda 683
           ********..5567*************7779********9666666666666655555555555555555555555555555555555550.....05555 PP
   S: 275  ..................................................................................................... 274
                                                                                                                
   Q: 684  esamnwlfahmddadiddpidfgaeskrdagvvgadtsmleemgfsaaqarkalrlnsnnaelavawlfenahdagqdehdvpearaavegstnssvipgn 784
           55555555555555555555555555555555566666666666666666666666666666666666666666667777777777777777777788888 PP
   S: 275  ...kkkYeLiavvvHsG.slssGHYvayvknekgkWllfdDskVtevkeeevleetg........staYvlfYkr 337
              + +Y  ++ ++H+G s++sGHYva+vk++++ W+lf+D+kV + + +  +++++        s aY++f++r
   Q: 785  sqlPATYTCTSFISHKGpSVHSGHYVAHVKQRDHTWVLFNDEKVVKAPLTCTVKQRDnvgvdalsSHAYLYFFQR 859
           888********************************************98777776668***************98 PP

UBD/Alpha-Helix/UBA

   S: 10   lveMGFdreealqaLraannnleaAveyLld 40
           l+eMGF+  +a++aLr ++nn+e Av++L++
   Q: 723  LEEMGFSAAQARKALRLNSNNAELAVAWLFE 753
           566**************************97 PP

Organism

Ustilago maydis

Protein Sequence
(Fasta)

MACPHLTAAF SALTPPRPSQ HVHKEECTLC FDDQDGPNGI DVCLLCFNGA CTGNGDREHS 60
RLHYEKTQHA LVVNIRRTRR PTPPASQAEA STVPKKLAIA AESDADKYDY HTVPKCLACD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCCTGTC CGCATCTCAC TGCCGCCTTT TCGGCGTTGA CGCCACCTCG TCCTTCGCAG 60
CATGTTCACA AGGAAGAGTG CACACTCTGC TTTGATGACC AAGATGGGCC CAACGGAATC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0479--Metal-binding
KW-0645--Protease
KW-1185--Reference proteome
KW-0788--Thiol protease
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001394--Peptidase_C19_UCH
IPR015940--UBA
IPR009060--UBA-like
IPR016652--Ubiquitinyl_hydrolase
IPR018200--USP_CS
IPR028889--USP_dom
IPR013083--Znf_RING/FYVE/PHD
IPR001607--Znf_UBP

PROSITE

PS50030--UBA
PS00972--USP_1
PS50235--USP_3
PS50271--ZF_UBP

Pfam

PF00627--UBA
PF00443--UCH
PF02148--zf-UBP

SMART

SM00165--UBA
SM00290--ZnF_UBP

Gene Ontology

GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0008270--F:zinc ion binding
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

KEGG

uma:UMAG_00298

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000394	Aegilops tauschii	31.87	4.00e-95	340.00
IUUC-Aml-002104	Ailuropoda melanoleuca	34.82	5.00e-128	450.00
IUUC-Atr-002580	Amborella trichopoda	32.83	2.00e-107	381.00
IUUC-Apl-003774	Anas platyrhynchos	33.33	2.00e-124	438.00
IUUC-Aca-005368	Anolis carolinensis	34.43	1.00e-132	465.00
IUUC-Aly-005727	Arabidopsis lyrata	33.22	3.00e-111	394.00
IUUC-Ath-006974	Arabidopsis thaliana	33.18	5.00e-111	393.00
IUUC-Ago-007890	Ashbya gossypii	30.75	5.00e-94	337.00
IUUC-Acl-008057	Aspergillus clavatus	42.15	7.00e-172	595.00
IUUC-Afl-008547	Aspergillus flavus	42.35	1.00e-148	518.00
IUUC-Afu-008805	Aspergillus fumigatus	40.34	9.00e-146	508.00
IUUC-Ani-009441	Aspergillus nidulans	40.39	3.00e-140	490.00
IUUC-Ang-009720	Aspergillus niger	42.33	3.00e-171	593.00
IUUC-Aor-010111	Aspergillus oryzae	41.88	3.00e-174	603.00
IUUC-Ate-010531	Aspergillus terreus	39.57	6.00e-148	516.00
IUUC-Ame-011470	Astyanax mexicanus	32.79	9.00e-109	386.00
IUUC-Bgr-012183	Blumeria graminis	43.15	1.00e-180	624.00
IUUC-Bta-013179	Bos taurus	34.78	3.00e-128	451.00
IUUC-Bci-013858	Botrytis cinerea	43.84	0.00e+00	662.00
IUUC-Bdi-014904	Brachypodium distachyon	34.38	1.00e-112	399.00
IUUC-Bol-015296	Brassica oleracea	33.71	3.00e-115	407.00
IUUC-Bra-017619	Brassica rapa	32.85	4.00e-112	397.00
IUUC-Cel-018625	Caenorhabditis elegans	29.14	8.00e-81	293.00
IUUC-Cja-019063	Callithrix jacchus	34.48	7.00e-124	436.00
IUUC-Cfa-020976	Canis familiaris	35.58	3.00e-131	460.00
IUUC-Cpo-022265	Cavia porcellus	35.43	1.00e-130	459.00
IUUC-Cre-022640	Chlamydomonas reinhardtii	32.15	1.00e-55	209.00
IUUC-Csa-024177	Chlorocebus sabaeus	34.88	3.00e-115	407.00
IUUC-Cho-024702	Choloepus hoffmanni	33.44	4.00e-79	287.00
IUUC-Cin-025411	Ciona intestinalis	31.87	2.00e-101	361.00
IUUC-Csv-026347	Ciona savignyi	30.22	2.00e-98	351.00
IUUC-Cgl-026667	Colletotrichum gloeosporioides	44.01	2.00e-174	604.00
IUUC-Cne-026831	Cryptococcus neoformans	47.89	0.00e+00	682.00
IUUC-Cme-027335	Cyanidioschyzon merolae	32.37	1.00e-87	316.00
IUUC-Dre-027982	Danio rerio	33.81	2.00e-102	365.00
IUUC-Dno-029034	Dasypus novemcinctus	34.78	6.00e-130	456.00
IUUC-Dor-030479	Dipodomys ordii	37.56	1.00e-62	233.00
IUUC-Dse-031467	Dothistroma septosporum	42.66	0.00e+00	628.00
IUUC-Dme-032075	Drosophila melanogaster	32.28	7.00e-97	346.00
IUUC-Ete-032865	Echinops telfairi	31.89	8.00e-111	393.00
IUUC-Eca-034059	Equus caballus	34.62	2.00e-128	451.00
IUUC-Eeu-035304	Erinaceus europaeus	35.58	3.00e-116	411.00
IUUC-Fca-035515	Felis catus	34.89	8.00e-129	452.00
IUUC-Fal-037271	Ficedula albicollis	34.96	2.00e-122	431.00
IUUC-Fox-037745	Fusarium oxysporum	45.74	0.00e+00	674.00
IUUC-Fso-038158	Fusarium solani	44.89	0.00e+00	653.00
IUUC-Gmo-039071	Gadus morhua	34.42	2.00e-109	388.00
IUUC-Ggr-040098	Gaeumannomyces graminis	43.25	2.00e-172	597.00
IUUC-Gga-040635	Gallus gallus	33.88	2.00e-131	461.00
IUUC-Gac-042528	Gasterosteus aculeatus	34.24	5.00e-108	384.00
IUUC-Gma-043614	Glycine max	34.16	2.00e-108	385.00
IUUC-Ggo-044602	Gorilla gorilla	34.56	2.00e-127	448.00
IUUC-Hsa-045959	Homo sapiens	34.56	2.00e-127	448.00
IUUC-Hvu-047563	Hordeum vulgare	36.32	2.00e-98	351.00
IUUC-Itr-048712	Ictidomys tridecemlineatus	34.34	2.00e-129	454.00
IUUC-Kpa-049156	Komagataella pastoris	37.07	2.00e-144	504.00
IUUC-Lch-049648	Latimeria chalumnae	34.62	3.00e-118	417.00
IUUC-Lpe-051523	Leersia perrieri	33.30	2.00e-103	368.00
IUUC-Loc-052072	Lepisosteus oculatus	31.36	7.00e-106	376.00
IUUC-Lma-053216	Leptosphaeria maculans	46.27	7.00e-177	613.00
IUUC-Laf-054327	Loxodonta africana	34.89	3.00e-128	451.00
IUUC-Mcc-055443	Macaca mulatta	34.34	1.00e-125	442.00
IUUC-Meu-056298	Macropus eugenii	34.04	2.00e-91	328.00
IUUC-Mor-057106	Magnaporthe oryzae	45.81	0.00e+00	667.00
IUUC-Mpo-057589	Magnaporthe poae	43.66	3.00e-176	610.00
IUUC-Mtr-058680	Medicago truncatula	33.71	9.00e-111	392.00
IUUC-Mla-058903	Melampsora laricipopulina	42.69	0.00e+00	643.00
IUUC-Mga-059669	Meleagris gallopavo	32.88	2.00e-122	431.00
IUUC-Mvi-060476	Microbotryum violaceum	46.81	0.00e+00	663.00
IUUC-Mmr-060575	Microcebus murinus	34.56	3.00e-128	451.00
IUUC-Mdo-062183	Monodelphis domestica	33.82	7.00e-128	449.00
IUUC-Mmu-063592	Mus musculus	35.01	8.00e-130	456.00
IUUC-Mac-065446	Musa acuminata	30.51	2.00e-94	338.00
IUUC-Mpu-066082	Mustela putorius furo	34.78	4.00e-129	453.00
IUUC-Mlu-067345	Myotis lucifugus	34.15	5.00e-126	443.00
IUUC-Nfi-068558	Neosartorya fischeri	41.75	5.00e-163	566.00
IUUC-Ncr-068960	Neurospora crassa	44.22	1.00e-178	618.00
IUUC-Nle-070173	Nomascus leucogenys	35.01	1.00e-128	452.00
IUUC-Opr-070556	Ochotona princeps	34.34	1.00e-127	449.00
IUUC-Ont-071502	Oreochromis niloticus	34.65	7.00e-110	389.00
IUUC-Oan-072959	Ornithorhynchus anatinus	39.82	9.00e-49	184.00
IUUC-Ocu-074861	Oryctolagus cuniculus	34.67	3.00e-130	457.00
IUUC-Oba-075109	Oryza barthii	33.29	1.00e-106	379.00
IUUC-Obr-076292	Oryza brachyantha	34.45	8.00e-108	382.00
IUUC-Ogl-077065	Oryza glaberrima	34.38	9.00e-113	399.00
IUUC-Ogu-078776	Oryza glumaepatula	32.98	2.00e-107	381.00
IUUC-Oin-080048	Oryza indica	34.42	6.00e-112	396.00
IUUC-Olo-080711	Oryza longistaminata	32.73	9.00e-98	349.00
IUUC-Ome-081506	Oryza meridionalis	33.42	4.00e-100	357.00
IUUC-Oni-082320	Oryza nivara	32.31	2.00e-104	371.00
IUUC-Opu-083801	Oryza punctata	33.14	3.00e-105	374.00
IUUC-Oru-085139	Oryza rufipogon	32.73	1.00e-103	369.00
IUUC-Osa-085713	Oryza sativa	34.49	3.00e-114	404.00
IUUC-Ola-086951	Oryzias latipes	33.44	2.00e-106	378.00
IUUC-Olu-087822	Ostreococcus lucimarinus	32.58	1.00e-95	342.00
IUUC-Oga-088625	Otolemur garnettii	33.82	1.00e-126	445.00
IUUC-Oar-089995	Ovis aries	35.08	9.00e-128	449.00
IUUC-Ptr-090640	Pan troglodytes	34.56	4.00e-129	453.00
IUUC-Pan-091974	Papio anubis	33.82	1.00e-124	439.00
IUUC-Psi-093957	Pelodiscus sinensis	34.09	4.00e-133	467.00
IUUC-Pma-094242	Petromyzon marinus	36.19	7.00e-69	252.00
IUUC-Pno-094835	Phaeosphaeria nodorum	44.67	1.00e-151	528.00
IUUC-Ppa-095901	Physcomitrella patens	34.05	7.00e-118	416.00
IUUC-Pfo-097148	Poecilia formosa	34.88	2.00e-110	392.00
IUUC-Pab-098068	Pongo abelii	32.33	8.00e-105	373.00
IUUC-Pop-098855	Populus trichocarpa	33.11	7.00e-106	376.00
IUUC-Pca-100738	Procavia capensis	34.62	3.00e-91	327.00
IUUC-Ppe-101315	Prunus persica	32.23	4.00e-104	370.00
IUUC-Pva-102154	Pteropus vampyrus	34.56	2.00e-127	448.00
IUUC-Pgr-103343	Puccinia graminis	43.61	8.00e-155	538.00
IUUC-Ptt-103928	Puccinia triticina	38.00	9.00e-143	499.00
IUUC-Pte-104306	Pyrenophora teres	44.41	1.00e-162	565.00
IUUC-Pyt-104696	Pyrenophora triticirepentis	44.41	2.00e-167	581.00
IUUC-Rno-105801	Rattus norvegicus	35.12	5.00e-130	456.00
IUUC-Sce-106304	Saccharomyces cerevisiae	29.71	1.00e-88	319.00
IUUC-Sha-107635	Sarcophilus harrisii	34.29	8.00e-129	452.00
IUUC-Sja-107678	Schizosaccharomyces japonicus	38.29	6.00e-152	529.00
IUUC-Spo-108144	Schizosaccharomyces pombe	37.62	1.00e-156	545.00
IUUC-Smo-108703	Selaginella moellendorffii	35.12	2.00e-113	401.00
IUUC-Sit-110728	Setaria italica	33.33	8.00e-115	406.00
IUUC-Sly-111523	Solanum lycopersicum	33.29	2.00e-116	412.00
IUUC-Sar-113733	Sorex araneus	32.78	2.00e-58	218.00
IUUC-Sbi-114419	Sorghum bicolor	33.64	5.00e-112	397.00
IUUC-Sre-115225	Sporisorium reilianum	79.58	0.00e+00	1291.00
IUUC-Ssc-115686	Sus scrofa	34.56	5.00e-130	456.00
IUUC-Tgu-117346	Taeniopygia guttata	33.37	3.00e-127	447.00
IUUC-Tru-118350	Takifugu rubripes	32.78	4.00e-109	387.00
IUUC-Tsy-119278	Tarsius syrichta	30.28	5.00e-88	317.00
IUUC-Tni-120658	Tetraodon nigroviridis	32.89	2.00e-101	361.00
IUUC-Tca-121585	Theobroma cacao	33.33	1.00e-104	372.00
IUUC-Tre-122043	Trichoderma reesei	44.34	0.00e+00	632.00
IUUC-Tvi-122303	Trichoderma virens	44.25	0.00e+00	634.00
IUUC-Tae-123798	Triticum aestivum	34.29	4.00e-112	397.00
IUUC-Tur-126732	Triticum urartu	31.93	2.00e-101	361.00
IUUC-Tme-126909	Tuber melanosporum	46.44	0.00e+00	669.00
IUUC-Tbe-127261	Tupaia belangeri	31.87	2.00e-41	162.00
IUUC-Ttr-129119	Tursiops truncatus	36.24	3.00e-65	241.00
IUUC-Vda-129688	Verticillium dahliae	44.75	0.00e+00	632.00
IUUC-Vpa-130170	Vicugna pacos	31.73	6.00e-50	190.00
IUUC-Vvi-131116	Vitis vinifera	33.11	2.00e-102	364.00
IUUC-Xtr-131953	Xenopus tropicalis	33.08	4.00e-110	390.00
IUUC-Xma-133837	Xiphophorus maculatus	34.88	2.00e-110	391.00
IUUC-Yli-134510	Yarrowia lipolytica	41.58	1.00e-152	531.00
IUUC-Zma-135786	Zea mays	33.76	6.00e-105	373.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence