iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Aca-004467

Ensembl Protein ID

ENSACAP00000007923.3

UniProt Accession

G1KHC9; G1KHC9_ANOCA

Protein Name

Uncharacterized protein

Gene Name

KIF21A

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSACAG00000007925.3	ENSACAT00000008090.3	ENSACAP00000007923.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	7.10e-28	95.4	1316	1350
UBD/Beta-Prp	5.50e-44	150.4	1420	1627

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclafsdtllvsGsdDgtikvWDlrtgvl 35
           gHt  v c++ +d+ll +Gs D t+kvW+l tg  
   Q: 1316 GHTKAVLCIDCTDDLLFTGSKDRTCKVWNLVTGQE 1350
           8**********78*****************99976 PP

UBD/Beta-Prp

   S: 50   gheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfsp..sg.dklvsGshdrtirvwdletgqclee.. 131
             e++++++ ++p+g +++ ++  ++++ wdl+ ++ + +l+gh   v++l++++  +g d +++Gs+d +i+++d+ +g       
   Q: 1420 AGENQINQIALNPTG-TFLYAAAGNAVRMWDLKRFQSTGKLTGHLGPVMCLTVDRisNGqDLIITGSKDHYIKMFDVTEGALGTVgp 1505
           56789*********9.9**************************************99888******************999876688 PP
   S: 132  ...tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecv 215
              ++ +h + +  +++++  + l+sGs D+ ++ Wdl++ +l+++   +h+d v  l   + ++ l+sg + g +klwd+ t   +
   Q: 1506 thnFEPPHYDGIEALTIMG--DNLFSGSRDNGIKKWDLAQRDLIQQVPNAHKDWVCALGPVPGSPVLLSGCRGGVLKLWDVDTCAPI 1590
           888999*************..6799**********************999************************************* PP
   S: 216  rtlnghtdnvksvrfspnderlvsgssDgsiriW....d 250
            +l+gh+++++ + +   +  + ++s+D+++riW    +
   Q: 1591 SELKGHDSPINAICTN--SSQIFTASDDRTVRIWkapnN 1627
           ***********87777..****************55532 PP

Organism

Anolis carolinensis

Protein Sequence
(Fasta)

MSAAQEESSV RVAVRIRPQL AKEKIEGCHI CTSVTPGEPQ VFLGKDKAFT FDYVFDIESQ 60
QEEIYVQCIN KLIEGCFEGY NATVFAYGQT GAGKTYTMGT GFDVNIMEEE QGIIPRAVKH 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TCAAGATGAC TAATTTCAGA ATTCATACTT GCCTTCAACA GACAAAAGTT CTTTCTCCCA 60
CCCTGGACAT TATACCACAG GTATATAAAC CCTGCCACAG CAACGCGTGG CCGGGCACGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0505--Motor protein
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR019821--Kinesin_motor_CS
IPR001752--Kinesin_motor_dom
IPR027417--P-loop_NTPase
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00411--KINESIN_MOTOR_1
PS50067--KINESIN_MOTOR_2
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00225--Kinesin
PF00400--WD40

PRINTS

PR00380--KINESINHEAVY

SMART

SM00129--KISc
SM00320--WD40

Gene Ontology

GO:0005871--C:kinesin complex
GO:0005524--F:ATP binding
GO:0016887--F:ATPase activity
GO:0003777--F:microtubule motor activity
GO:0007018--P:microtubule-based movement

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001391	Ailuropoda melanoleuca	84.84	0.00e+00	2747.00
IUUC-Apl-003353	Anas platyrhynchos	83.46	0.00e+00	2677.00
IUUC-Ame-011430	Astyanax mexicanus	66.34	0.00e+00	1302.00
IUUC-Bta-013485	Bos taurus	83.90	0.00e+00	2655.00
IUUC-Cel-018402	Caenorhabditis elegans	51.47	8.00e-150	525.00
IUUC-Cja-019385	Callithrix jacchus	82.46	0.00e+00	2635.00
IUUC-Cfa-020986	Canis familiaris	84.48	0.00e+00	2685.00
IUUC-Cpo-022297	Cavia porcellus	82.85	0.00e+00	2622.00
IUUC-Csa-023685	Chlorocebus sabaeus	83.50	0.00e+00	2691.00
IUUC-Cho-024531	Choloepus hoffmanni	85.20	0.00e+00	991.00
IUUC-Cin-025160	Ciona intestinalis	44.99	7.00e-86	311.00
IUUC-Csv-026158	Ciona savignyi	57.44	3.00e-175	609.00
IUUC-Dre-028532	Danio rerio	64.85	0.00e+00	1285.00
IUUC-Dno-029972	Dasypus novemcinctus	80.90	0.00e+00	2531.00
IUUC-Ete-032872	Echinops telfairi	69.35	0.00e+00	922.00
IUUC-Eca-033518	Equus caballus	84.15	0.00e+00	2700.00
IUUC-Fca-036197	Felis catus	84.61	0.00e+00	2685.00
IUUC-Fal-037534	Ficedula albicollis	86.63	0.00e+00	2727.00
IUUC-Gmo-039407	Gadus morhua	67.21	0.00e+00	1381.00
IUUC-Gga-040687	Gallus gallus	85.41	0.00e+00	2664.00
IUUC-Gac-041626	Gasterosteus aculeatus	68.41	0.00e+00	2174.00
IUUC-Ggo-044457	Gorilla gorilla	83.92	0.00e+00	2677.00
IUUC-Hsa-046372	Homo sapiens	84.08	0.00e+00	2694.00
IUUC-Loc-052689	Lepisosteus oculatus	73.80	0.00e+00	2367.00
IUUC-Laf-054018	Loxodonta africana	80.50	0.00e+00	2522.00
IUUC-Mcc-055558	Macaca mulatta	84.26	0.00e+00	2700.00
IUUC-Meu-056080	Macropus eugenii	84.47	0.00e+00	936.00
IUUC-Mga-059283	Meleagris gallopavo	83.79	0.00e+00	2632.00
IUUC-Mmr-060773	Microcebus murinus	83.35	0.00e+00	2623.00
IUUC-Mdo-062688	Monodelphis domestica	82.84	0.00e+00	2456.00
IUUC-Mmu-063997	Mus musculus	81.14	0.00e+00	1627.00
IUUC-Mpu-066354	Mustela putorius furo	85.41	0.00e+00	2708.00
IUUC-Mlu-067599	Myotis lucifugus	83.72	0.00e+00	2663.00
IUUC-Nle-069477	Nomascus leucogenys	84.26	0.00e+00	2701.00
IUUC-Opr-070188	Ochotona princeps	73.08	0.00e+00	1591.00
IUUC-Ont-071938	Oreochromis niloticus	68.88	0.00e+00	2169.00
IUUC-Oan-073055	Ornithorhynchus anatinus	82.61	0.00e+00	2536.00
IUUC-Ocu-074302	Oryctolagus cuniculus	81.64	0.00e+00	2644.00
IUUC-Ola-086604	Oryzias latipes	66.47	0.00e+00	2103.00
IUUC-Oga-088799	Otolemur garnettii	83.54	0.00e+00	2398.00
IUUC-Oar-089629	Ovis aries	84.27	0.00e+00	2647.00
IUUC-Pan-092214	Papio anubis	85.05	0.00e+00	2705.00
IUUC-Psi-093757	Pelodiscus sinensis	84.32	0.00e+00	2553.00
IUUC-Pfo-096978	Poecilia formosa	66.12	0.00e+00	1315.00
IUUC-Pab-097984	Pongo abelii	84.38	0.00e+00	2696.00
IUUC-Pca-101061	Procavia capensis	72.55	0.00e+00	1295.00
IUUC-Pva-102306	Pteropus vampyrus	84.49	0.00e+00	2622.00
IUUC-Rno-105354	Rattus norvegicus	81.14	0.00e+00	1608.00
IUUC-Sha-106938	Sarcophilus harrisii	81.55	0.00e+00	1670.00
IUUC-Ssc-115810	Sus scrofa	83.45	0.00e+00	2642.00
IUUC-Tgu-117076	Taeniopygia guttata	85.91	0.00e+00	2601.00
IUUC-Tru-118091	Takifugu rubripes	64.70	0.00e+00	1251.00
IUUC-Tsy-119020	Tarsius syrichta	84.78	0.00e+00	2687.00
IUUC-Tni-120813	Tetraodon nigroviridis	67.29	0.00e+00	2131.00
IUUC-Tbe-127494	Tupaia belangeri	71.60	0.00e+00	897.00
IUUC-Ttr-128393	Tursiops truncatus	79.08	0.00e+00	2443.00
IUUC-Vpa-130675	Vicugna pacos	91.25	0.00e+00	681.00
IUUC-Xtr-132829	Xenopus tropicalis	77.33	0.00e+00	2507.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence