iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Pab-098109

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

POC1 centriolar protein homolog B

Genbank Nucleotide ID

ABGA01314329

Gene Name

POC1B

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPPYG00000004819.2	ENSPPYT00000005707.2	ENSPPYP00000005494.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.00e-55	183.3	143	178
UBD/Beta-Prp	1.50e-74	251.0	98	300

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvl 35
           Ht +v+c +f +d +l+vs+s D+tik+WD++   +
   Q: 143  HTHWVRCAKFsPDgRLIVSCSEDKTIKIWDTTNKQC 178
           9**********999****************987665 PP

UBD/Beta-Prp

   S: 6    kghhksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghe 94
           +++h++++++v+fs d+++lat+s+d++ikvw++ ++ +l sl+ h+  v++ kfspdg ++v++seD+tik+wd  + +cv  ++   
   Q: 98   FKAHTAPVRSVDFSADGQFLATASEDKSIKVWSMYRQRFLYSLYRHTHWVRCAKFSPDGRLIVSCSEDKTIKIWDTTNKQCVNNFSDSV 186
           45677777777777777777777777777777777777777777777777777777777777777777777777777777777777666 PP
   S: 95   dsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsv 183
             +  ++f+psg  ++s+++d+t++vwd++ ++ l+   ++h+g vnc+++hp+gn+lv++s D+t+++ dl  g+l++tl+g ht++v
   Q: 187  GFANFVDFNPSGTCIASAGSDQTVKVWDVRVNKLLQ-HYQVHSGGVNCISFHPSGNYLVTASSDGTLKILDLLEGRLIYTLQG-HTGPV 273
           666667777777777777777777777777777777.7777777777777777777777777777777777777777777777.77777 PP
   S: 184  yslsfdsngkelvsgsldgtvklwdlq 210
             +sf++ g+ ++sg+ d++v lw   
   Q: 274  FTVSFSKGGELFASGGADTQVLLWRTN 300
           777777777777777777777777654 PP

Organism

Pongo abelii

Protein Sequence
(Fasta)

MASATEDPVL ERYFKGHKAA ITSLDLSPNG KQLATASWDT FLMLWNFKPH ARAYRYVGHK 60
DVVTSVQFSP HGNLLASASR DRTVRLWIPD KRGKFSEFKA HTAPVRSVDF SADGQFLATA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TCCAGCTGTG TAAGTTTAGT GCTCTAAGGT GTACGCAAAT GAGCAGATGA GAATGGAAAC 60
ATATCGCAGA AAATTATTAA GTGCATGCAC AACATTTATT CATTCATTCA CTCATTCATT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0005814--C:centriole
GO:0036064--C:ciliary basal body
GO:0000922--C:spindle pole
GO:0008283--P:cell proliferation
GO:0060271--P:cilium assembly
GO:0001895--P:retina homeostasis

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002219	Ailuropoda melanoleuca	88.81	0.00e+00	824.00
IUUC-Apl-004219	Anas platyrhynchos	62.16	4.00e-162	564.00
IUUC-Aca-005197	Anolis carolinensis	58.59	2.00e-172	598.00
IUUC-Ame-011000	Astyanax mexicanus	55.88	1.00e-156	546.00
IUUC-Bta-012706	Bos taurus	90.15	0.00e+00	891.00
IUUC-Cja-019185	Callithrix jacchus	92.63	0.00e+00	892.00
IUUC-Cfa-021274	Canis familiaris	90.70	0.00e+00	886.00
IUUC-Cpo-022351	Cavia porcellus	84.23	0.00e+00	856.00
IUUC-Csa-023032	Chlorocebus sabaeus	92.68	0.00e+00	886.00
IUUC-Cho-024508	Choloepus hoffmanni	80.00	0.00e+00	677.00
IUUC-Dre-028703	Danio rerio	56.72	3.00e-156	544.00
IUUC-Dno-028915	Dasypus novemcinctus	89.64	0.00e+00	838.00
IUUC-Dor-030306	Dipodomys ordii	75.06	0.00e+00	653.00
IUUC-Dme-032182	Drosophila melanogaster	45.85	3.00e-80	292.00
IUUC-Ete-032353	Echinops telfairi	73.87	0.00e+00	683.00
IUUC-Eca-034136	Equus caballus	91.46	0.00e+00	833.00
IUUC-Eeu-034611	Erinaceus europaeus	79.84	0.00e+00	627.00
IUUC-Fca-036205	Felis catus	89.22	0.00e+00	780.00
IUUC-Fal-036947	Ficedula albicollis	53.59	3.00e-138	484.00
IUUC-Gga-040847	Gallus gallus	60.17	1.00e-162	566.00
IUUC-Ggo-045194	Gorilla gorilla	98.95	0.00e+00	972.00
IUUC-Hsa-047026	Homo sapiens	98.95	0.00e+00	972.00
IUUC-Itr-048943	Ictidomys tridecemlineatus	88.34	0.00e+00	827.00
IUUC-Lch-050067	Latimeria chalumnae	59.09	2.00e-172	598.00
IUUC-Loc-052409	Lepisosteus oculatus	58.05	9.00e-164	569.00
IUUC-Laf-053428	Loxodonta africana	89.64	0.00e+00	856.00
IUUC-Mcc-054772	Macaca mulatta	98.74	0.00e+00	968.00
IUUC-Meu-056496	Macropus eugenii	73.98	3.00e-165	574.00
IUUC-Mga-059276	Meleagris gallopavo	59.92	1.00e-165	575.00
IUUC-Mmr-061525	Microcebus murinus	91.42	0.00e+00	904.00
IUUC-Mdo-062351	Monodelphis domestica	69.80	0.00e+00	722.00
IUUC-Mmu-063834	Mus musculus	82.85	0.00e+00	828.00
IUUC-Mpu-066453	Mustela putorius furo	86.82	0.00e+00	851.00
IUUC-Mlu-067909	Myotis lucifugus	88.31	0.00e+00	806.00
IUUC-Nle-069206	Nomascus leucogenys	98.33	0.00e+00	985.00
IUUC-Opr-070566	Ochotona princeps	78.01	0.00e+00	747.00
IUUC-Ont-072587	Oreochromis niloticus	59.34	1.00e-135	476.00
IUUC-Oan-073726	Ornithorhynchus anatinus	66.82	7.00e-173	599.00
IUUC-Ocu-074639	Oryctolagus cuniculus	91.63	0.00e+00	908.00
IUUC-Ola-086913	Oryzias latipes	52.42	3.00e-145	508.00
IUUC-Oga-088061	Otolemur garnettii	91.62	0.00e+00	681.00
IUUC-Oar-090228	Ovis aries	84.95	0.00e+00	877.00
IUUC-Ptr-091420	Pan troglodytes	99.16	0.00e+00	975.00
IUUC-Pan-092228	Papio anubis	98.54	0.00e+00	966.00
IUUC-Psi-093309	Pelodiscus sinensis	62.45	4.00e-169	587.00
IUUC-Pca-101012	Procavia capensis	68.41	0.00e+00	634.00
IUUC-Pva-102712	Pteropus vampyrus	90.38	0.00e+00	890.00
IUUC-Rno-105260	Rattus norvegicus	82.01	0.00e+00	826.00
IUUC-Sar-113446	Sorex araneus	76.78	0.00e+00	763.00
IUUC-Ssc-115794	Sus scrofa	91.87	0.00e+00	717.00
IUUC-Tgu-116770	Taeniopygia guttata	55.00	2.00e-142	498.00
IUUC-Tru-117968	Takifugu rubripes	54.81	1.00e-148	519.00
IUUC-Tsy-119316	Tarsius syrichta	79.50	0.00e+00	709.00
IUUC-Tbe-128071	Tupaia belangeri	88.25	0.00e+00	781.00
IUUC-Ttr-129267	Tursiops truncatus	89.96	0.00e+00	889.00
IUUC-Vpa-130823	Vicugna pacos	82.14	3.00e-176	610.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence