iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Nle-070133

Ensembl Protein ID

ENSNLEP00000019594.2

UniProt Accession

G1S256; G1S256_NOMLE

Genbank Protein ID

ENSNLEP00000019594

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ADFV01123553

Gene Name

RNF34

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSNLEG00000016163.2	ENSNLET00000020584.2	ENSNLEP00000019594.2

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	85.60	4.00e-152	534.00	IUUC-Rno-105481

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Nomascus leucogenys

Protein Sequence
(Fasta)

MRKAGATSMW ASCCGLLNEV MGTGAVRGQQ SGFAGATGPF RFTPNPEFST YPPAATEGPN 60
IVCKACGLSF SVFRKKHVCC DCKKDFCSVC SVLQENLRRC STCHLLQETA FQRPQLMRLK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCCGCGTCCT AGCGAGTGCA GCTGCCGCTC CTTACCGGAC CCACAAGTGA GGAGCCCCGA 60
GGTCATCACC GAGCGTGAAC GCGGGAACGT CTGGGAAGGA AATCTGAGGC CCTGCTCTGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR003034--SAP_dom
IPR011011--Znf_FYVE_PHD
IPR013083--Znf_RING/FYVE/PHD

Gene Ontology

GO:0005737--C:cytoplasm
GO:0016604--C:nuclear body
GO:0005886--C:plasma membrane
GO:1901981--F:phosphatidylinositol phosphate binding
GO:0061630--F:ubiquitin protein ligase activity
GO:2001271--P:negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis
GO:1902042--P:negative regulation of extrinsic apoptotic signaling pathway via death domain receptors
GO:1901797--P:negative regulation of signal transduction by p53 class mediator
GO:0035872--P:nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0070936--P:protein K48-linked ubiquitination
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002341	Ailuropoda melanoleuca	90.70	7.00e-160	556.00
IUUC-Apl-003398	Anas platyrhynchos	72.16	1.00e-123	435.00
IUUC-Aca-005050	Anolis carolinensis	67.30	5.00e-79	286.00
IUUC-Bta-012886	Bos taurus	92.11	1.00e-164	572.00
IUUC-Cja-019045	Callithrix jacchus	96.88	1.00e-170	592.00
IUUC-Cfa-020037	Canis familiaris	89.30	2.00e-159	555.00
IUUC-Cpo-021618	Cavia porcellus	78.69	3.00e-132	464.00
IUUC-Csa-023303	Chlorocebus sabaeus	94.97	5.00e-173	600.00
IUUC-Cho-024671	Choloepus hoffmanni	83.52	7.00e-160	556.00
IUUC-Dre-027887	Danio rerio	59.84	1.00e-89	323.00
IUUC-Dno-029136	Dasypus novemcinctus	91.48	2.00e-172	598.00
IUUC-Dor-030596	Dipodomys ordii	85.23	1.00e-143	502.00
IUUC-Ete-032684	Echinops telfairi	87.46	2.00e-138	485.00
IUUC-Eca-033598	Equus caballus	92.46	2.00e-167	581.00
IUUC-Eeu-034878	Erinaceus europaeus	91.53	2.00e-164	571.00
IUUC-Fca-036370	Felis catus	89.78	1.00e-162	565.00
IUUC-Fal-036937	Ficedula albicollis	73.94	1.00e-121	429.00
IUUC-Gga-040411	Gallus gallus	73.07	1.00e-116	412.00
IUUC-Gac-042281	Gasterosteus aculeatus	59.03	2.00e-98	352.00
IUUC-Ggo-044752	Gorilla gorilla	98.59	1.00e-174	605.00
IUUC-Hsa-046299	Homo sapiens	98.86	6.00e-174	603.00
IUUC-Itr-047907	Ictidomys tridecemlineatus	89.92	9.00e-161	559.00
IUUC-Lch-049616	Latimeria chalumnae	64.58	1.00e-95	342.00
IUUC-Loc-052099	Lepisosteus oculatus	60.37	2.00e-106	378.00
IUUC-Laf-054103	Loxodonta africana	85.39	2.00e-153	534.00
IUUC-Mcc-055295	Macaca mulatta	95.51	8.00e-172	595.00
IUUC-Mga-059584	Meleagris gallopavo	72.49	5.00e-116	410.00
IUUC-Mmr-061766	Microcebus murinus	92.50	7.00e-172	596.00
IUUC-Mdo-062738	Monodelphis domestica	74.59	2.00e-124	438.00
IUUC-Mmu-064403	Mus musculus	87.64	2.00e-147	514.00
IUUC-Mpu-066021	Mustela putorius furo	90.70	7.00e-167	579.00
IUUC-Mlu-067144	Myotis lucifugus	91.78	1.00e-156	545.00
IUUC-Opr-070683	Ochotona princeps	82.05	1.00e-151	528.00
IUUC-Ont-072065	Oreochromis niloticus	58.95	3.00e-95	341.00
IUUC-Oan-073504	Ornithorhynchus anatinus	82.82	2.00e-147	514.00
IUUC-Ocu-074382	Oryctolagus cuniculus	87.82	6.00e-161	559.00
IUUC-Ola-087022	Oryzias latipes	58.17	4.00e-99	354.00
IUUC-Oga-087963	Otolemur garnettii	90.88	2.00e-174	604.00
IUUC-Oar-089439	Ovis aries	91.27	1.00e-162	565.00
IUUC-Ptr-091616	Pan troglodytes	98.30	9.00e-170	589.00
IUUC-Pan-092754	Papio anubis	95.52	4.00e-173	600.00
IUUC-Psi-093217	Pelodiscus sinensis	68.21	2.00e-106	378.00
IUUC-Pab-098124	Pongo abelii	98.87	4.00e-175	607.00
IUUC-Pca-100954	Procavia capensis	90.14	4.00e-168	583.00
IUUC-Pva-102588	Pteropus vampyrus	89.30	2.00e-161	561.00
IUUC-Rno-105481	Rattus norvegicus	85.60	1.00e-149	522.00
IUUC-Sha-106640	Sarcophilus harrisii	80.68	2.00e-133	468.00
IUUC-Sar-113331	Sorex araneus	92.33	3.00e-166	577.00
IUUC-Tgu-117252	Taeniopygia guttata	72.68	1.00e-117	416.00
IUUC-Tru-118556	Takifugu rubripes	58.24	4.00e-99	354.00
IUUC-Tsy-118891	Tarsius syrichta	66.20	7.00e-68	250.00
IUUC-Tni-119741	Tetraodon nigroviridis	55.65	1.00e-95	342.00
IUUC-Tbe-127380	Tupaia belangeri	92.02	3.00e-171	594.00
IUUC-Ttr-128999	Tursiops truncatus	90.45	1.00e-165	575.00
IUUC-Vpa-130168	Vicugna pacos	79.28	2.00e-92	331.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence