iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Tru-118119

Ensembl Protein ID

ENSTRUP00000044114.1

UniProt Accession

H2V4I0; H2V4I0_TAKRU

Protein Name

DCN1-like protein; Defective in cullin neddylation protein 1-like protein

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTRUG00000017216.1	ENSTRUT00000044262.1	ENSTRUP00000044114.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/DCUN1	3.60e-88	295.8	59	246
UBD/Alpha-Helix/UBA	6.80e-07	30.5	6	44

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/DCUN1

   S: 1    vskkkleelferYkdpqed.ligieglekfcedlgvdpediavLvlawkleaatlcefsreefldgltalgcdsieklqeklktlesel 88
           v++kkle+l++rYkdpq++ +igi+g+++fc+dl +dp+++++Lv+awk++aat+c fsr+efldg+ +lgcds+ekl++ l++le+el
   Q: 59   VDRKKLEQLYNRYKDPQDEnKIGIDGIQQFCDDLMLDPASVSILVVAWKFRAATQCVFSRKEFLDGMAELGCDSTEKLKAILPRLEQEL 147
           589**************999********************************************************************* PP
   S: 89   kdeqkfkdiYrfafnfakdkgqksldldtaialwkLllaerefklldawlkfLeeekkksiskDtWnllLefskviakdlsnYdeegaW 177
           kd  kfkd+Y+f+fnfak++gqk+ldl++a+a+w+L+l+er fk+l++w++fL e++k+si+kDtWnllL+f ++ia+d+snYdeegaW
   Q: 148  KDSGKFKDFYQFTFNFAKNPGQKGLDLEMAVAYWNLILTER-FKFLELWNRFLLEHHKRSIPKDTWNLLLDFGNMIADDMSNYDEEGAW 235
           **************************************999.*********************************************** PP
   S: 178  PvliDefveyl 188
           PvliD+fve++
   Q: 236  PVLIDNFVEFA 246
           *********97 PP

UBD/Alpha-Helix/UBA

   S: 2    ededkleqlve.MGFdreealqaLraannnleaAveyLl 39
           +++dk++q+++ +   + +a+ +L+++++ le+A+++++
   Q: 6    SQKDKIRQFMSfTQAAERTAVYCLAQNDWKLEVATDNYF 44
           699********6666666*******************99 PP

Organism

Takifugu rubripes

Protein Sequence
(Fasta)

HKLKSSQKDK IRQFMSFTQA AERTAVYCLA QNDWKLEVAT DNYFQNPDLY YKESMKTSVD 60
RKKLEQLYNR YKDPQDENKI GIDGIQQFCD DLMLDPASVS ILVVAWKFRA ATQCVFSRKE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CACAAGCTGA AGTCGTCGCA GAAAGACAAG ATTCGGCAGT TCATGTCCTT CACGCAGGCT 60
GCGGAGAGGA CGGCCGTCTA CTGCCTGGCC CAGAATGATT GGAAACTAGA AGTTGCTACA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR014764--DCN-prot
IPR011992--EF-hand-dom_pair
IPR005176--PONY_dom
IPR009060--UBA-like

PROSITE

PS51229--DCUN1

Pfam

PF03556--Cullin_binding

Gene Ontology

GO:0000151--C:ubiquitin ligase complex
GO:0097602--F:cullin family protein binding
GO:0031624--F:ubiquitin conjugating enzyme binding
GO:0032182--F:ubiquitin-like protein binding
GO:0051443--P:positive regulation of ubiquitin-protein transferase activity
GO:0045116--P:protein neddylation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aca-005059	Anolis carolinensis	88.14	7.00e-129	452.00
IUUC-Ago-007806	Ashbya gossypii	25.49	5.00e-18	84.70
IUUC-Ate-010414	Aspergillus terreus	30.62	5.00e-29	120.00
IUUC-Ame-011553	Astyanax mexicanus	93.78	1.00e-136	478.00
IUUC-Cpo-021832	Cavia porcellus	82.49	4.00e-130	457.00
IUUC-Csa-023108	Chlorocebus sabaeus	82.88	8.00e-133	466.00
IUUC-Cgl-026386	Colletotrichum gloeosporioides	30.73	3.00e-22	97.80
IUUC-Fox-037884	Fusarium oxysporum	35.17	9.00e-19	86.30
IUUC-Fso-038150	Fusarium solani	32.16	1.00e-20	94.00
IUUC-Gac-041853	Gasterosteus aculeatus	90.70	3.00e-141	494.00
IUUC-Ggo-044972	Gorilla gorilla	82.49	6.00e-132	462.00
IUUC-Hsa-046994	Homo sapiens	81.71	2.00e-131	461.00
IUUC-Kpa-049127	Komagataella pastoris	29.48	3.00e-23	102.00
IUUC-Mcc-054700	Macaca mulatta	82.88	1.00e-132	465.00
IUUC-Meu-056791	Macropus eugenii	75.00	4.00e-111	393.00
IUUC-Nle-069475	Nomascus leucogenys	82.10	1.00e-131	461.00
IUUC-Ont-071910	Oreochromis niloticus	93.41	2.00e-145	508.00
IUUC-Ptr-091595	Pan troglodytes	82.10	2.00e-131	461.00
IUUC-Pan-092825	Papio anubis	82.88	7.00e-133	466.00
IUUC-Pab-098197	Pongo abelii	81.89	5.00e-124	436.00
IUUC-Pte-104398	Pyrenophora teres	31.58	2.50e-01	26.60
IUUC-Sce-106358	Saccharomyces cerevisiae	26.67	5.00e-21	94.70
IUUC-Smo-108750	Selaginella moellendorffii	41.87	8.00e-51	193.00
IUUC-Sbi-114082	Sorghum bicolor	43.90	3.00e-61	228.00
IUUC-Sre-115221	Sporisorium reilianum	27.40	3.00e-24	105.00
IUUC-Tni-120315	Tetraodon nigroviridis	96.90	4.00e-150	523.00
IUUC-Uma-129364	Ustilago maydis	30.30	1.00e-32	133.00
IUUC-Vda-129929	Verticillium dahliae	31.34	2.00e-21	97.10

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence