iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oar-089957

Ensembl Protein ID

ENSOARP00000021236.1

UniProt Accession

W5QET8; W5QET8_SHEEP

Genbank Protein ID

ENSOARP00000021236

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AMGL01102306

Gene Name

TEP1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOARG00000019765.1	ENSOART00000021531.1	ENSOARP00000021236.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.40e-51	170.3	2063	2098
UBD/Beta-Prp	4.40e-72	242.9	2011	2194

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgv 34
           gH+++v+c++f s+ ++l++G++D ++ +WD+rt +
   Q: 2063 GHEGPVSCCSFsSEgCRLATGGRDRSLLCWDVRTPK 2098
           8**********9889*****************9976 PP

UBD/Beta-Prp

   S: 47   slsgheaevtavkfspdgkilvtgseDrtikvw.........dlstgkcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdle 124
            ls h ++v  +  s++  +l+ +seD t+++w           ++++    l+ghe  v ++sfs +g +l++G++dr + +wd++
   Q: 2011 LLSRHRKPVLGLATSQE--LLAVASEDFTVRLWprqllmlpqKTEDFPHGTELRGHEGPVSCCSFSSEGCRLATGGRDRSLLCWDVR 2095
           58999*******99999..9*************666666544444777788889********************************* PP
   S: 125  tgqclee...tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklwd 208
           t +       + + h+++v++ ++ + ++ll s+s D+ v lWd ++ + l ++ g h+++v  +   +  +++vs+++dgt+k+wd
   Q: 2096 TPKAPVLiccFSACHRDWVTGCAWTK-DSLLLSCSSDGSVALWDPESRQQLGHFLG-HQHAVSAVVAVE--EHVVSVGRDGTLKVWD 2178
           *9987767888999**********99.89**************************9.******999888..69************** PP
   S: 209  lqtgecvrtlnghtdnv 225
            q  e + +  +h++++
   Q: 2179 HQGVE-MTSIPAHSAPI 2194
           98555.56666666655 PP

Organism

Ovis aries

Protein Sequence
(Fasta)

MEKCHECAST HMDILSLKNQ CLATFLYPKM SEKPLGHVST HSDILSLENR CLATLPDLKT 60
LEKPPGHVSA HSDILSLENR CLATLPDLKT LEKPPGHVSA HSDILSLENR CLATLTILKS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGAGAAAT GCCATGAGTG TGCGTCTACC CACATGGACA TCCTTTCCTT GAAGAACCAG 60
TGCCTGGCCA CATTTCTTTA CCCAAAGATG TCGGAGAAAC CGCTTGGGCA TGTGTCTACT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR025139--DUF4062
IPR007111--NACHT_NTPase
IPR027417--P-loop_NTPase
IPR008850--TEP1_N
IPR008858--TROVE_dom
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS50837--NACHT
PS51226--TEP1_N
PS50988--TROVE
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF13271--DUF4062
PF05386--TEP1_N
PF05731--TROVE
PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0005737--C:cytoplasm
GO:0016363--C:nuclear matrix
GO:0005697--C:telomerase holoenzyme complex
GO:0003720--F:telomerase activity
GO:0070034--F:telomerase RNA binding
GO:0000722--P:telomere maintenance via recombination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001482	Ailuropoda melanoleuca	78.55	0.00e+00	3778.00
IUUC-Aca-005102	Anolis carolinensis	42.61	0.00e+00	1604.00
IUUC-Ame-011822	Astyanax mexicanus	34.84	5.00e-176	613.00
IUUC-Bta-012323	Bos taurus	94.48	0.00e+00	4690.00
IUUC-Cja-019005	Callithrix jacchus	78.48	0.00e+00	3945.00
IUUC-Cfa-020803	Canis familiaris	71.81	0.00e+00	3342.00
IUUC-Cpo-022312	Cavia porcellus	72.43	0.00e+00	3335.00
IUUC-Csa-023287	Chlorocebus sabaeus	78.89	0.00e+00	3898.00
IUUC-Dre-028825	Danio rerio	35.28	0.00e+00	1123.00
IUUC-Dno-029455	Dasypus novemcinctus	76.68	0.00e+00	3655.00
IUUC-Dor-030328	Dipodomys ordii	71.18	0.00e+00	2417.00
IUUC-Ete-032385	Echinops telfairi	72.93	0.00e+00	1880.00
IUUC-Eca-033726	Equus caballus	81.79	0.00e+00	4051.00
IUUC-Eeu-034665	Erinaceus europaeus	63.80	0.00e+00	942.00
IUUC-Fca-035365	Felis catus	79.86	0.00e+00	3887.00
IUUC-Gmo-039584	Gadus morhua	31.84	5.00e-116	413.00
IUUC-Gac-042307	Gasterosteus aculeatus	36.08	0.00e+00	988.00
IUUC-Ggo-045432	Gorilla gorilla	76.32	0.00e+00	3679.00
IUUC-Hsa-046182	Homo sapiens	78.67	0.00e+00	3902.00
IUUC-Itr-049021	Ictidomys tridecemlineatus	77.39	0.00e+00	3773.00
IUUC-Lch-050186	Latimeria chalumnae	39.51	2.00e-76	279.00
IUUC-Laf-054524	Loxodonta africana	76.90	0.00e+00	3804.00
IUUC-Mcc-055628	Macaca mulatta	79.27	0.00e+00	3926.00
IUUC-Meu-056338	Macropus eugenii	62.75	0.00e+00	1262.00
IUUC-Mmr-060854	Microcebus murinus	78.35	0.00e+00	3841.00
IUUC-Mdo-062247	Monodelphis domestica	60.64	0.00e+00	2700.00
IUUC-Mmu-064406	Mus musculus	71.01	0.00e+00	3431.00
IUUC-Mpu-065806	Mustela putorius furo	78.19	0.00e+00	3827.00
IUUC-Mlu-068116	Myotis lucifugus	80.76	0.00e+00	3850.00
IUUC-Nle-069628	Nomascus leucogenys	79.52	0.00e+00	3475.00
IUUC-Opr-070242	Ochotona princeps	77.07	0.00e+00	2717.00
IUUC-Oan-073598	Ornithorhynchus anatinus	51.88	0.00e+00	1842.00
IUUC-Ocu-073933	Oryctolagus cuniculus	76.93	0.00e+00	3730.00
IUUC-Ola-086886	Oryzias latipes	35.50	0.00e+00	1023.00
IUUC-Oga-088609	Otolemur garnettii	76.05	0.00e+00	3708.00
IUUC-Ptr-090577	Pan troglodytes	77.00	0.00e+00	3839.00
IUUC-Pan-092397	Papio anubis	78.77	0.00e+00	3924.00
IUUC-Pma-094373	Petromyzon marinus	35.13	2.00e-70	260.00
IUUC-Pfo-096497	Poecilia formosa	36.04	0.00e+00	1029.00
IUUC-Pab-098028	Pongo abelii	78.33	0.00e+00	3867.00
IUUC-Pca-101002	Procavia capensis	81.92	0.00e+00	1839.00
IUUC-Pva-102144	Pteropus vampyrus	73.90	0.00e+00	1689.00
IUUC-Rno-105828	Rattus norvegicus	70.33	0.00e+00	3440.00
IUUC-Sha-106469	Sarcophilus harrisii	60.17	0.00e+00	2745.00
IUUC-Sar-113035	Sorex araneus	70.64	0.00e+00	2006.00
IUUC-Ssc-116122	Sus scrofa	86.19	0.00e+00	3121.00
IUUC-Tru-118412	Takifugu rubripes	32.40	0.00e+00	1100.00
IUUC-Tsy-119257	Tarsius syrichta	71.34	0.00e+00	1469.00
IUUC-Tni-120032	Tetraodon nigroviridis	37.79	1.00e-36	146.00
IUUC-Tbe-127312	Tupaia belangeri	62.37	0.00e+00	879.00
IUUC-Ttr-128335	Tursiops truncatus	86.22	0.00e+00	3662.00
IUUC-Xtr-132524	Xenopus tropicalis	39.12	0.00e+00	1332.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence