iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ani-009415

Ensembl Protein ID

CADANIAP00004986

UniProt Accession

Q5B6U3; C8V7B2; CMR1_EMENI

Genbank Protein ID

EAA59945.1; CBF75499.1

Protein Name

DNA damage-binding protein cmr1

Genbank Nucleotide ID

AACD01000061; BN001302

Gene Name

ANIA_03737; AN3737

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
CADANIAG00004986	CADANIAT00004986	CADANIAP00004986

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.20e-11	42.7	352	372

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 12   sd.tllvsGsdDgtikvWDlr 31
           +  ++++++s D t+++WD+r
   Q: 352  THpHYVATASLDRTMRLWDIR 372
           34489**************86 PP

Organism

Aspergillus nidulans

Functional Description
(View)

DNA-binding protein that binds to both single- and double-stranded DNA. Binds preferentially to UV-damaged DNA. May be involved in DNA-metabolic processes.

Protein Sequence
(Fasta)

MVKEELSEFE KQRLANIAER DALLKKLSLD AQSTGVFTSN MPRGTSANQS KPKKKPAPKV 60
KKEESLLPRR TSSRLRGIAA DSEIAKRKAD EEYDRRQEEE RAKRVRKSDS FSFNDIFVSG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CACCATGGTT AAGGAGGAAC TTTCCGAATT CGAGAAGCAG CGGCTCGCCA ATATCGCCGA 60
GCGCGATGCG CTTCTCAAGA AGCTCAGCCT CGACGCGCAG TCGACAGGTG TCTTTACCTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0227--DNA damage
KW-0238--DNA-binding
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR033052--Cmr1/WDR76
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

SMART

SM00320--WD40

Gene Ontology

GO:0005737--C:cytoplasm
GO:0000790--C:nuclear chromatin
GO:0034399--C:nuclear periphery
GO:0003677--F:DNA binding
GO:0006974--P:cellular response to DNA damage stimulus
GO:2000001--P:regulation of DNA damage checkpoint

KEGG

ani:AN3737.2

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000625	Aegilops tauschii	27.75	8.00e-17	79.30
IUUC-Atr-002605	Amborella trichopoda	24.62	4.00e-19	87.80
IUUC-Apl-003441	Anas platyrhynchos	26.99	3.00e-25	107.00
IUUC-Aca-004241	Anolis carolinensis	29.18	1.00e-29	122.00
IUUC-Aly-005444	Arabidopsis lyrata	25.35	2.00e-25	108.00
IUUC-Ath-007550	Arabidopsis thaliana	24.51	1.00e-23	102.00
IUUC-Ago-007715	Ashbya gossypii	31.13	6.00e-54	203.00
IUUC-Acl-008370	Aspergillus clavatus	77.90	0.00e+00	828.00
IUUC-Afl-008586	Aspergillus flavus	79.13	0.00e+00	816.00
IUUC-Afu-008907	Aspergillus fumigatus	80.50	0.00e+00	812.00
IUUC-Ang-009597	Aspergillus niger	66.36	2.00e-143	500.00
IUUC-Aor-010197	Aspergillus oryzae	78.94	0.00e+00	816.00
IUUC-Ate-010280	Aspergillus terreus	76.46	0.00e+00	811.00
IUUC-Bgr-012236	Blumeria graminis	47.14	7.00e-133	465.00
IUUC-Bta-013059	Bos taurus	26.33	3.00e-28	118.00
IUUC-Bci-013796	Botrytis cinerea	52.52	2.00e-145	506.00
IUUC-Bdi-015040	Brachypodium distachyon	29.34	8.00e-23	99.80
IUUC-Bol-015934	Brassica oleracea	26.29	9.00e-19	86.30
IUUC-Bra-018032	Brassica rapa	24.53	2.00e-21	95.90
IUUC-Cja-019043	Callithrix jacchus	25.60	2.00e-30	125.00
IUUC-Cfa-021103	Canis familiaris	25.53	4.00e-26	111.00
IUUC-Cpo-021508	Cavia porcellus	26.89	3.00e-28	118.00
IUUC-Cre-022967	Chlamydomonas reinhardtii	21.23	2.00e-10	58.90
IUUC-Csa-023555	Chlorocebus sabaeus	25.81	9.00e-29	119.00
IUUC-Cin-025651	Ciona intestinalis	24.16	5.00e-21	94.00
IUUC-Cgl-026604	Colletotrichum gloeosporioides	48.09	8.00e-126	442.00
IUUC-Cne-027093	Cryptococcus neoformans	29.17	2.00e-39	155.00
IUUC-Cme-027238	Cyanidioschyzon merolae	25.20	7.00e-21	93.60
IUUC-Dre-027441	Danio rerio	26.14	1.00e-29	122.00
IUUC-Dno-029575	Dasypus novemcinctus	26.84	9.00e-27	113.00
IUUC-Dor-030554	Dipodomys ordii	26.61	3.00e-28	117.00
IUUC-Dse-031299	Dothistroma septosporum	54.25	2.00e-146	510.00
IUUC-Ete-032716	Echinops telfairi	26.29	2.00e-15	75.90
IUUC-Eca-034027	Equus caballus	25.55	4.00e-15	74.30
IUUC-Eeu-035234	Erinaceus europaeus	26.79	1.00e-08	53.10
IUUC-Fca-035892	Felis catus	25.13	5.00e-25	107.00
IUUC-Fal-036986	Ficedula albicollis	25.68	4.00e-23	100.00
IUUC-Fox-037750	Fusarium oxysporum	47.74	2.00e-127	447.00
IUUC-Fso-038198	Fusarium solani	50.98	2.00e-120	424.00
IUUC-Gga-040479	Gallus gallus	26.80	5.00e-15	73.90
IUUC-Gac-042043	Gasterosteus aculeatus	26.67	1.00e-21	95.90
IUUC-Gma-043913	Glycine max	24.68	5.00e-27	113.00
IUUC-Ggo-045290	Gorilla gorilla	26.13	2.00e-31	128.00
IUUC-Hsa-047021	Homo sapiens	26.40	4.00e-31	127.00
IUUC-Hvu-047193	Hordeum vulgare	28.37	2.00e-22	98.60
IUUC-Itr-047914	Ictidomys tridecemlineatus	27.56	3.00e-30	124.00
IUUC-Kpa-049275	Komagataella pastoris	31.44	1.00e-68	252.00
IUUC-Lch-049718	Latimeria chalumnae	27.44	4.00e-30	124.00
IUUC-Lpe-051708	Leersia perrieri	26.63	6.00e-23	100.00
IUUC-Loc-052565	Lepisosteus oculatus	24.25	5.00e-30	124.00
IUUC-Lma-053276	Leptosphaeria maculans	54.88	6.00e-154	536.00
IUUC-Laf-053970	Loxodonta africana	27.82	6.00e-33	134.00
IUUC-Mcc-054740	Macaca mulatta	25.54	2.00e-28	119.00
IUUC-Meu-056546	Macropus eugenii	29.01	3.00e-12	65.50
IUUC-Mtr-058451	Medicago truncatula	24.95	2.00e-29	121.00
IUUC-Mla-059117	Melampsora laricipopulina	32.39	1.00e-48	186.00
IUUC-Mga-059328	Meleagris gallopavo	25.20	6.00e-22	97.10
IUUC-Mvi-060555	Microbotryum violaceum	30.83	5.00e-37	147.00
IUUC-Mmr-061520	Microcebus murinus	26.86	3.00e-30	125.00
IUUC-Mdo-062812	Monodelphis domestica	25.67	4.00e-29	120.00
IUUC-Mmu-064011	Mus musculus	25.53	1.00e-22	99.80
IUUC-Mpu-066486	Mustela putorius furo	26.63	3.00e-26	111.00
IUUC-Mlu-067721	Myotis lucifugus	25.45	2.00e-19	88.60
IUUC-Nfi-068314	Neosartorya fischeri	80.69	0.00e+00	811.00
IUUC-Ncr-068896	Neurospora crassa	50.19	5.00e-131	459.00
IUUC-Nle-069369	Nomascus leucogenys	25.87	1.00e-30	126.00
IUUC-Opr-070975	Ochotona princeps	26.50	2.00e-27	115.00
IUUC-Ont-072528	Oreochromis niloticus	25.28	7.00e-26	109.00
IUUC-Oan-072955	Ornithorhynchus anatinus	24.64	3.00e-21	94.70
IUUC-Ocu-074561	Oryctolagus cuniculus	25.34	4.00e-27	114.00
IUUC-Oba-074982	Oryza barthii	25.71	1.00e-26	113.00
IUUC-Obr-076551	Oryza brachyantha	27.21	5.00e-19	85.90
IUUC-Ogl-077685	Oryza glaberrima	26.63	9.00e-28	116.00
IUUC-Ogu-078331	Oryza glumaepatula	26.63	1.00e-27	115.00
IUUC-Oin-079507	Oryza indica	26.42	4.00e-26	110.00
IUUC-Olo-080604	Oryza longistaminata	27.53	3.00e-24	104.00
IUUC-Ome-081816	Oryza meridionalis	25.71	2.00e-24	105.00
IUUC-Oni-082051	Oryza nivara	26.63	1.00e-27	115.00
IUUC-Opu-083372	Oryza punctata	26.35	8.00e-27	112.00
IUUC-Oru-084578	Oryza rufipogon	26.63	1.00e-27	115.00
IUUC-Osa-086177	Oryza sativa	26.63	1.00e-27	115.00
IUUC-Ola-087208	Oryzias latipes	28.32	4.00e-24	103.00
IUUC-Olu-087680	Ostreococcus lucimarinus	29.26	7.00e-23	100.00
IUUC-Oga-088104	Otolemur garnettii	27.35	7.00e-31	127.00
IUUC-Oar-090157	Ovis aries	25.40	2.00e-27	115.00
IUUC-Ptr-091615	Pan troglodytes	26.13	5.00e-31	127.00
IUUC-Pan-092212	Papio anubis	25.54	3.00e-28	118.00
IUUC-Psi-092950	Pelodiscus sinensis	26.30	5.00e-27	114.00
IUUC-Pma-094625	Petromyzon marinus	30.77	3.00e-12	63.90
IUUC-Pno-094824	Phaeosphaeria nodorum	56.00	2.00e-159	553.00
IUUC-Ppa-095414	Physcomitrella patens	21.45	4.00e-10	58.20
IUUC-Pfo-096922	Poecilia formosa	25.14	7.00e-28	117.00
IUUC-Pab-097591	Pongo abelii	26.40	2.00e-31	128.00
IUUC-Pop-099337	Populus trichocarpa	24.65	3.00e-27	114.00
IUUC-Pca-101025	Procavia capensis	26.26	4.00e-29	120.00
IUUC-Ppe-101256	Prunus persica	26.60	8.00e-17	80.10
IUUC-Pva-102453	Pteropus vampyrus	26.93	2.00e-29	122.00
IUUC-Pgr-103436	Puccinia graminis	30.58	2.00e-51	194.00
IUUC-Ptt-103899	Puccinia triticina	35.35	2.00e-38	151.00
IUUC-Pte-104258	Pyrenophora teres	54.84	5.00e-158	549.00
IUUC-Pyt-104625	Pyrenophora triticirepentis	54.65	7.00e-156	541.00
IUUC-Rno-104843	Rattus norvegicus	25.00	1.00e-22	100.00
IUUC-Sce-106189	Saccharomyces cerevisiae	34.78	3.00e-49	187.00
IUUC-Sha-106672	Sarcophilus harrisii	24.87	2.00e-30	125.00
IUUC-Smo-109660	Selaginella moellendorffii	27.27	2.00e-23	100.00
IUUC-Sit-109704	Setaria italica	26.69	2.00e-29	121.00
IUUC-Sly-111853	Solanum lycopersicum	25.07	3.00e-25	107.00
IUUC-Stu-112482	Solanum tuberosum	24.62	5.00e-25	107.00
IUUC-Sbi-114517	Sorghum bicolor	26.50	2.00e-23	102.00
IUUC-Sre-114960	Sporisorium reilianum	25.81	2.00e-28	119.00
IUUC-Ssc-115568	Sus scrofa	26.13	3.00e-29	121.00
IUUC-Tgu-117276	Taeniopygia guttata	23.76	3.00e-16	77.80
IUUC-Tru-117559	Takifugu rubripes	32.00	5.00e-07	44.70
IUUC-Tsy-119234	Tarsius syrichta	23.34	3.00e-14	71.60
IUUC-Tni-120358	Tetraodon nigroviridis	24.57	1.00e-26	112.00
IUUC-Tca-121273	Theobroma cacao	24.15	1.00e-21	96.30
IUUC-Tre-121932	Trichoderma reesei	49.90	6.00e-134	469.00
IUUC-Tvi-122567	Trichoderma virens	50.29	3.00e-142	496.00
IUUC-Tae-123506	Triticum aestivum	27.45	4.00e-23	100.00
IUUC-Tur-125970	Triticum urartu	27.31	2.00e-16	77.80
IUUC-Tme-126958	Tuber melanosporum	39.32	5.00e-81	293.00
IUUC-Tbe-127425	Tupaia belangeri	27.08	3.00e-29	121.00
IUUC-Ttr-129123	Tursiops truncatus	27.35	1.00e-26	113.00
IUUC-Uma-129495	Ustilago maydis	27.27	1.00e-27	116.00
IUUC-Vda-129981	Verticillium dahliae	49.62	7.00e-127	446.00
IUUC-Vpa-130437	Vicugna pacos	25.40	4.00e-28	118.00
IUUC-Vvi-131430	Vitis vinifera	25.43	5.00e-25	107.00
IUUC-Xtr-132670	Xenopus tropicalis	24.34	4.00e-26	111.00
IUUC-Xma-133375	Xiphophorus maculatus	26.55	2.00e-24	105.00
IUUC-Yli-134341	Yarrowia lipolytica	32.87	5.00e-68	249.00
IUUC-Zma-135413	Zea mays	25.78	3.00e-27	114.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence