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Tag Content
UUCD2 ID IUUC-Xtr-132479
UUCD1 version UUC-XeT-00937
Ensembl Protein ID ENSXETP00000027235.3
UniProt Accession Q5XGG5; CCNF_XENTR
Genbank Protein ID AAH84474.1
Protein Name Cyclin-F
Genbank Nucleotide ID BC084474
Gene Name ccnf
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSXETG00000012459.3 ENSXETT00000027235.3 ENSXETP00000027235.3
Status Unreviewed
Classification
Family Identity E-Value Score Source Orthology
E3 adaptor/Cullin RING/SCF/F-box 67.58 0.00e+00 810.00 IUUC-Hsa-046867
Active Site
Position(s) Description Evidence
N/A N/A N/A
Organism Xenopus tropicalis
Functional Description
(View)

Functional Description



     Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins during G2 phase.
Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins during G2 phase.
Protein Sequence
(Fasta)
MKGGALHCRC SKCFAAPPKR RVKRRPRVLT LLSLPEDVLL YVLECLPAVD ILSMREVHPH 60
LRSLVDSHSS VWARASFQDV WPSPENLNLF ERAAECGNFE ACVKLGIAYL YNEGLSLSDD 120
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Protein Fasta Sequence



>IUUC-Xtr-132479|E3,F-box|Xenopus tropicalis
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Nucleotide Sequence
(Fasta)
CTGAGCCAGG CGGTAGCACC GATTCCCACT GCTCATCTAC CTCACCAGCT AATTGCTCGG 60
CATGAAGGGA GGAGGTAAGT GTCTGACAGG CGTAGATCTG ATATAACTGA TATTTATGTT 120
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Nucleotide Fasta Sequence



>IUUC-Xtr-132479|E3,F-box|Xenopus tropicalis
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Sequence Source Ensembl
Keyword

KW-0131--Cell cycle
KW-0132--Cell division
KW-0181--Complete proteome
KW-0195--Cyclin
KW-0963--Cytoplasm
KW-0206--Cytoskeleton
KW-0498--Mitosis
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR028857--CCNF_metazoan
IPR013763--Cyclin-like
IPR004367--Cyclin_C-dom
IPR006671--Cyclin_N
IPR001810--F-box_dom
IPR013780--Glyco_hydro_b

PROSITE

PS00292--CYCLINS
PS50181--FBOX

Pfam

PF02984--Cyclin_C
PF00134--Cyclin_N
PF00646--F-box

SMART

SM00385--CYCLIN
SM01332--Cyclin_C
SM00256--FBOX

Gene Ontology

GO:0005814--C:centriole
GO:0005634--C:nucleus
GO:0019005--C:SCF ubiquitin ligase complex
GO:0051301--P:cell division
GO:0007067--P:mitotic nuclear division
GO:0010826--P:negative regulation of centrosome duplication
GO:0016567--P:protein ubiquitination
GO:0031146--P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process

KEGG xtr:496496
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001520 Ailuropoda melanoleuca 65.76 0.00e+00 800.00
IUUC-Apl-003215 Anas platyrhynchos 65.14 0.00e+00 922.00
IUUC-Ani-009145 Aspergillus nidulans 40.62 5.70e+00 26.60
IUUC-Ame-011700 Astyanax mexicanus 61.44 0.00e+00 691.00
IUUC-Bta-013230 Bos taurus 59.67 0.00e+00 797.00
IUUC-Cja-019256 Callithrix jacchus 66.87 0.00e+00 818.00
IUUC-Cfa-020123 Canis familiaris 66.57 0.00e+00 816.00
IUUC-Cpo-021599 Cavia porcellus 65.66 0.00e+00 843.00
IUUC-Csa-023518 Chlorocebus sabaeus 61.47 0.00e+00 736.00
IUUC-Dre-028186 Danio rerio 58.21 0.00e+00 669.00
IUUC-Dno-029401 Dasypus novemcinctus 66.62 0.00e+00 826.00
IUUC-Dor-031087 Dipodomys ordii 62.95 0.00e+00 774.00
IUUC-Ete-032869 Echinops telfairi 72.78 1.00e-64 240.00
IUUC-Eca-033473 Equus caballus 66.31 0.00e+00 811.00
IUUC-Eeu-034533 Erinaceus europaeus 57.96 4.00e-105 375.00
IUUC-Fca-035961 Felis catus 65.81 0.00e+00 801.00
IUUC-Fal-036659 Ficedula albicollis 63.33 0.00e+00 872.00
IUUC-Gmo-039557 Gadus morhua 57.28 0.00e+00 629.00
IUUC-Gga-040389 Gallus gallus 68.38 0.00e+00 760.00
IUUC-Gac-042059 Gasterosteus aculeatus 62.10 0.00e+00 688.00
IUUC-Ggo-044497 Gorilla gorilla 67.02 0.00e+00 819.00
IUUC-Hsa-046867 Homo sapiens 67.02 0.00e+00 816.00
IUUC-Itr-047922 Ictidomys tridecemlineatus 59.09 0.00e+00 839.00
IUUC-Lch-050143 Latimeria chalumnae 65.83 0.00e+00 809.00
IUUC-Loc-052538 Lepisosteus oculatus 73.33 4.00e-50 189.00
IUUC-Laf-054481 Loxodonta africana 67.17 0.00e+00 801.00
IUUC-Mcc-055426 Macaca mulatta 67.02 0.00e+00 832.00
IUUC-Meu-056150 Macropus eugenii 63.65 0.00e+00 772.00
IUUC-Mga-059822 Meleagris gallopavo 60.48 0.00e+00 707.00
IUUC-Mmr-061785 Microcebus murinus 66.57 0.00e+00 821.00
IUUC-Mdo-062763 Monodelphis domestica 72.99 0.00e+00 906.00
IUUC-Mmu-064391 Mus musculus 65.43 0.00e+00 812.00
IUUC-Mpu-065756 Mustela putorius furo 65.96 0.00e+00 804.00
IUUC-Mlu-067607 Myotis lucifugus 66.42 0.00e+00 810.00
IUUC-Nle-069147 Nomascus leucogenys 67.43 0.00e+00 819.00
IUUC-Opr-071129 Ochotona princeps 65.96 0.00e+00 845.00
IUUC-Ont-072031 Oreochromis niloticus 62.50 0.00e+00 723.00
IUUC-Oan-073514 Ornithorhynchus anatinus 68.93 1.00e-139 489.00
IUUC-Ocu-074914 Oryctolagus cuniculus 66.21 0.00e+00 806.00
IUUC-Ola-086606 Oryzias latipes 59.94 0.00e+00 674.00
IUUC-Oga-088632 Otolemur garnettii 67.47 0.00e+00 807.00
IUUC-Oar-090320 Ovis aries 62.35 0.00e+00 765.00
IUUC-Ptr-091175 Pan troglodytes 67.02 0.00e+00 816.00
IUUC-Pan-092003 Papio anubis 66.87 0.00e+00 817.00
IUUC-Psi-093719 Pelodiscus sinensis 62.79 0.00e+00 879.00
IUUC-Pma-094390 Petromyzon marinus 55.75 1.00e-122 432.00
IUUC-Pfo-096911 Poecilia formosa 55.61 0.00e+00 724.00
IUUC-Pab-097562 Pongo abelii 66.87 0.00e+00 828.00
IUUC-Pca-100748 Procavia capensis 51.61 1.00e-81 297.00
IUUC-Pva-102168 Pteropus vampyrus 63.06 0.00e+00 752.00
IUUC-Rno-105157 Rattus norvegicus 66.27 0.00e+00 817.00
IUUC-Sha-107184 Sarcophilus harrisii 72.66 0.00e+00 903.00
IUUC-Sar-113086 Sorex araneus 55.47 1.00e-67 250.00
IUUC-Ssc-116347 Sus scrofa 65.66 0.00e+00 795.00
IUUC-Tgu-117463 Taeniopygia guttata 63.12 0.00e+00 874.00
IUUC-Tru-118348 Takifugu rubripes 60.18 0.00e+00 725.00
IUUC-Tsy-119459 Tarsius syrichta 60.17 9.00e-66 244.00
IUUC-Tni-120853 Tetraodon nigroviridis 62.42 0.00e+00 685.00
IUUC-Tbe-127361 Tupaia belangeri 55.91 2.00e-145 509.00
IUUC-Ttr-128214 Tursiops truncatus 64.15 5.00e-170 591.00
Created Date 25-Jun-2017

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