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Basic Information Integrated Annotations
Tag Content
UUCD2 ID IUUC-Mmu-063678
UUCD1 version UUC-MuM-01221
Ensembl Protein ID ENSMUSP00000124382.1
UniProt Accession E9PXY8; E9PXY8_MOUSE
Genbank Protein ID ENSMUSP00000124382
Protein Name Ubiquitin carboxyl-terminal hydrolase 7
Genbank Nucleotide ID AC115005
Gene Name Usp7
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSMUSG00000022710.17 ENSMUST00000160405.7 ENSMUSP00000124382.1
ENSMUSG00000022710.17 ENSMUST00000160326.7 ENSMUSP00000124576.1
ENSMUSG00000022710.17 ENSMUST00000161046.8 ENSMUSP00000124093.2
ENSMUSG00000022710.17 ENSMUST00000172505.1 ENSMUSP00000133398.1
Annotation
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpressGXD
DNA & RNA Element
AREsitemiRTarBasemicroRNATRANSFAC
RepTarRAID2
Protein-protein Interaction
HINT
Post-translational Modifications (PTMs)
CPLMdbPAFPHOSIDAmUbiSiDa
Protein Expression/Proteomics
GPMDB
Status Unreviewed
Classification
Family E-Value Score Start End
DUB/USP 1.80e-68 232.4 255 561
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   DUB/USP
   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgyeq 89
           +GlkN+g+tCYmNS+LQ+L+++++lr+++    + +      +++++++  +lq++f el ++++k v +++l+k++++e   +++++q
   Q: 255  VGLKNQGATCYMNSLLQTLFFTNQLRKAVYM-MPTEG-----DDSSKSVPLALQRVFYEL-QHSDKPVGTKKLTKSFGWET--LDSFMQ 334
           6******************************.44433.....466889************.88889************887..67**** PP
   S: 90   qDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpvpg 178
           +D+qE++++lld++e+++                          k +  + +i +lF+g++ s i+c++ d +s r+e+ +d++l+++g
   Q: 335  HDVQELCRVLLDNVENKM--------------------------KGTCVEGTIPKLFRGKMVSYIQCKDVDYRSDRREDYYDIQLSIKG 397
           ******************..........................789****************************************** PP
   S: 179  keetkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlspfcts 267
           k+     ++ +++ ++++ e+l+g+nky   +  ++qeaek +k+ +lP+vL+l+L+Rf ++ ++++++kin+++efp++L l++f+++
   Q: 398  KK-----NIFESFVDYVAVEQLDGDNKYDAGEH-GLQEAEKGVKFLTLPPVLHLQLMRFMYDPQTDQNIKINDRFEFPEQLPLDEFLQK 480
           **.....9*********************9996.7****************************************************** PP
   S: 268  peekqkekkkYeLiavvvHsGslssGHYvayvkn.ekgkWllfdDskVtevkeeevleetg............staYvlfYkr 337
           ++ k+  + +Y L+av+vHsG  ++GHYv+y +   +gkW++fdD+ V+ +++ee  e +             ++aY+l+Y r
   Q: 481  TDPKD--PANYILHAVLVHSGDNHGGHYVVYLNPkGDGKWCKFDDDVVSRCTKEEAIEHNYgghdddlsvrhcTNAYMLVYIR 561
           88777..*************************9834566************86666664446*******************87 PP
   
Organism Mus musculus
Protein Sequence
(Fasta)
MASSTSPPRS PSGRILTQDT IYFPQSNIIS ELLPWYLRYT PPEVPSTSVI TKFILVNCPW 60
NEGIEYQAGD TDDPPRITQN PVINGNVTLS DGHSNAEEDM EDDTSWRSEA TFQFTVERFS 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Mmu-063678|DUB,USP|Mus musculus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
GAACTCTTCC TGCACCGTGT CTTCCTGGAC GCTGTGATGC ATCACGTCGT GACGATAGTG 60
GACCTCTGAA ACTGTAAGTC AGCCCCATTT AAATGTTTTT TATAAGAGTT GCCTTGTTCC 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Mmu-063678|DUB,USP|Mus musculus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome
Interpro

IPR002083--MATH/TRAF_dom
IPR001394--Peptidase_C19_UCH
IPR008974--TRAF-like
IPR024729--USP7_ICP0-binding_dom
IPR029346--USP_C
IPR018200--USP_CS
IPR028889--USP_dom
PROSITE

PS50144--MATH
PS00972--USP_1
PS00973--USP_2
PS50235--USP_3
Pfam

PF00917--MATH
PF00443--UCH
PF14533--USP7_C2
PF12436--USP7_ICP0_bdg
SMART

SM00061--MATH
Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000761 Aegilops tauschii 33.30 1.00e-142 501.00
IUUC-Aml-002408 Ailuropoda melanoleuca 98.34 0.00e+00 2206.00
IUUC-Atr-003067 Amborella trichopoda 36.95 2.00e-123 437.00
IUUC-Apl-003558 Anas platyrhynchos 96.38 0.00e+00 2189.00
IUUC-Aca-004518 Anolis carolinensis 90.78 0.00e+00 2049.00
IUUC-Aly-006453 Arabidopsis lyrata 37.10 6.00e-161 561.00
IUUC-Ath-006591 Arabidopsis thaliana 36.52 9.00e-157 548.00
IUUC-Ago-007849 Ashbya gossypii 32.79 2.00e-139 490.00
IUUC-Acl-008327 Aspergillus clavatus 34.11 1.00e-170 593.00
IUUC-Afl-008491 Aspergillus flavus 34.57 8.00e-164 571.00
IUUC-Afu-008804 Aspergillus fumigatus 35.13 3.00e-162 566.00
IUUC-Ang-009776 Aspergillus niger 34.88 4.00e-162 565.00
IUUC-Aor-009998 Aspergillus oryzae 33.83 1.00e-155 544.00
IUUC-Ate-010428 Aspergillus terreus 34.63 1.00e-164 573.00
IUUC-Ame-010903 Astyanax mexicanus 92.84 0.00e+00 2122.00
IUUC-Bgr-012132 Blumeria graminis 32.01 7.00e-144 505.00
IUUC-Bta-013192 Bos taurus 98.43 0.00e+00 2208.00
IUUC-Bci-013924 Botrytis cinerea 34.04 2.00e-150 527.00
IUUC-Bdi-014920 Brachypodium distachyon 35.82 7.00e-157 548.00
IUUC-Bol-015224 Brassica oleracea 36.86 2.00e-157 550.00
IUUC-Bra-017853 Brassica rapa 36.91 6.00e-156 545.00
IUUC-Cel-018219 Caenorhabditis elegans 33.87 4.00e-155 542.00
IUUC-Cja-019006 Callithrix jacchus 97.24 0.00e+00 2174.00
IUUC-Cfa-020361 Canis familiaris 98.43 0.00e+00 2207.00
IUUC-Cpo-022320 Cavia porcellus 99.08 0.00e+00 2217.00
IUUC-Cre-022708 Chlamydomonas reinhardtii 43.84 1.00e-91 330.00
IUUC-Csa-024050 Chlorocebus sabaeus 98.80 0.00e+00 2212.00
IUUC-Cho-024434 Choloepus hoffmanni 90.29 0.00e+00 1432.00
IUUC-Cin-025689 Ciona intestinalis 54.33 0.00e+00 1211.00
IUUC-Csv-025963 Ciona savignyi 52.41 0.00e+00 1164.00
IUUC-Cgl-026650 Colletotrichum gloeosporioides 33.48 7.00e-151 528.00
IUUC-Cne-026968 Cryptococcus neoformans 36.55 1.00e-180 627.00
IUUC-Cme-027103 Cyanidioschyzon merolae 35.69 9.00e-115 409.00
IUUC-Dre-028510 Danio rerio 93.02 0.00e+00 2125.00
IUUC-Dno-029696 Dasypus novemcinctus 98.34 0.00e+00 2199.00
IUUC-Dor-030611 Dipodomys ordii 83.84 0.00e+00 958.00
IUUC-Dse-031433 Dothistroma septosporum 34.74 2.00e-147 517.00
IUUC-Dme-031583 Drosophila melanogaster 48.49 0.00e+00 1041.00
IUUC-Ete-033191 Echinops telfairi 96.12 0.00e+00 2153.00
IUUC-Eca-034122 Equus caballus 97.97 0.00e+00 2199.00
IUUC-Eeu-035292 Erinaceus europaeus 84.06 0.00e+00 677.00
IUUC-Fca-036377 Felis catus 98.25 0.00e+00 2202.00
IUUC-Fal-036964 Ficedula albicollis 96.59 0.00e+00 2149.00
IUUC-Fox-037695 Fusarium oxysporum 33.39 8.00e-159 554.00
IUUC-Fso-038084 Fusarium solani 33.54 2.00e-158 553.00
IUUC-Gmo-038644 Gadus morhua 92.51 0.00e+00 2118.00
IUUC-Ggr-040029 Gaeumannomyces graminis 33.67 1.00e-156 548.00
IUUC-Gga-040944 Gallus gallus 96.63 0.00e+00 2181.00
IUUC-Gac-041740 Gasterosteus aculeatus 93.07 0.00e+00 2125.00
IUUC-Gma-043300 Glycine max 36.73 1.00e-168 587.00
IUUC-Ggo-044947 Gorilla gorilla 98.71 0.00e+00 2211.00
IUUC-Hsa-046278 Homo sapiens 98.80 0.00e+00 2212.00
IUUC-Hvu-047749 Hordeum vulgare 37.01 9.00e-142 498.00
IUUC-Itr-047904 Ictidomys tridecemlineatus 99.25 0.00e+00 1903.00
IUUC-Kpa-049121 Komagataella pastoris 31.03 1.00e-125 444.00
IUUC-Lch-049847 Latimeria chalumnae 95.47 0.00e+00 2168.00
IUUC-Lpe-051505 Leersia perrieri 35.60 3.00e-143 503.00
IUUC-Loc-052234 Lepisosteus oculatus 92.67 0.00e+00 1414.00
IUUC-Lma-053169 Leptosphaeria maculans 36.77 7.00e-168 585.00
IUUC-Laf-053566 Loxodonta africana 98.89 0.00e+00 2205.00
IUUC-Mcc-055549 Macaca mulatta 96.42 0.00e+00 2205.00
IUUC-Meu-056887 Macropus eugenii 88.25 0.00e+00 1279.00
IUUC-Mor-057149 Magnaporthe oryzae 34.42 5.00e-158 552.00
IUUC-Mpo-057536 Magnaporthe poae 33.51 5.00e-157 548.00
IUUC-Mtr-058583 Medicago truncatula 37.56 5.00e-164 572.00
IUUC-Mla-058899 Melampsora laricipopulina 37.05 1.00e-170 593.00
IUUC-Mga-060148 Meleagris gallopavo 96.56 0.00e+00 2194.00
IUUC-Mvi-060207 Microbotryum violaceum 37.62 0.00e+00 634.00
IUUC-Mmr-060946 Microcebus murinus 98.61 0.00e+00 2206.00
IUUC-Mdo-062079 Monodelphis domestica 90.19 0.00e+00 1967.00
IUUC-Mac-065416 Musa acuminata 37.07 9.00e-157 548.00
IUUC-Mpu-066744 Mustela putorius furo 98.77 0.00e+00 2158.00
IUUC-Mlu-067949 Myotis lucifugus 96.36 0.00e+00 2179.00
IUUC-Nfi-068342 Neosartorya fischeri 35.47 4.00e-162 565.00
IUUC-Ncr-068818 Neurospora crassa 33.48 1.00e-162 567.00
IUUC-Nle-070064 Nomascus leucogenys 98.89 0.00e+00 2214.00
IUUC-Opr-071001 Ochotona princeps 97.59 0.00e+00 1819.00
IUUC-Ont-072095 Oreochromis niloticus 92.47 0.00e+00 2117.00
IUUC-Oan-073483 Ornithorhynchus anatinus 97.44 0.00e+00 2131.00
IUUC-Ocu-073967 Oryctolagus cuniculus 98.47 0.00e+00 2124.00
IUUC-Oba-075811 Oryza barthii 34.14 6.00e-141 495.00
IUUC-Obr-076514 Oryza brachyantha 36.59 2.00e-155 543.00
IUUC-Ogl-077038 Oryza glaberrima 35.79 2.00e-150 526.00
IUUC-Ogu-078265 Oryza glumaepatula 34.19 5.00e-136 479.00
IUUC-Oin-079513 Oryza indica 35.24 3.00e-142 499.00
IUUC-Olo-080297 Oryza longistaminata 32.97 4.00e-124 439.00
IUUC-Ome-081879 Oryza meridionalis 36.37 2.00e-151 530.00
IUUC-Oni-082409 Oryza nivara 33.55 5.00e-140 492.00
IUUC-Opu-083199 Oryza punctata 35.64 3.00e-147 516.00
IUUC-Oru-085109 Oryza rufipogon 35.76 3.00e-146 512.00
IUUC-Osa-085418 Oryza sativa 38.82 5.00e-131 462.00
IUUC-Ola-086640 Oryzias latipes 92.79 0.00e+00 2116.00
IUUC-Olu-087874 Ostreococcus lucimarinus 32.93 7.00e-144 505.00
IUUC-Oga-089059 Otolemur garnettii 91.71 0.00e+00 2008.00
IUUC-Oar-089710 Ovis aries 98.52 0.00e+00 2206.00
IUUC-Ptr-091334 Pan troglodytes 98.71 0.00e+00 2211.00
IUUC-Pan-091717 Papio anubis 99.43 0.00e+00 2146.00
IUUC-Psi-093933 Pelodiscus sinensis 95.77 0.00e+00 2191.00
IUUC-Pma-094648 Petromyzon marinus 82.97 0.00e+00 1716.00
IUUC-Pno-095020 Phaeosphaeria nodorum 35.26 4.00e-150 526.00
IUUC-Ppa-096020 Physcomitrella patens 34.71 7.00e-162 565.00
IUUC-Pfo-096181 Poecilia formosa 92.38 0.00e+00 2118.00
IUUC-Pab-098231 Pongo abelii 96.12 0.00e+00 2137.00
IUUC-Pop-100083 Populus trichocarpa 36.77 4.00e-160 559.00
IUUC-Pca-100543 Procavia capensis 80.73 0.00e+00 1009.00
IUUC-Ppe-101523 Prunus persica 36.07 9.00e-155 541.00
IUUC-Pva-102472 Pteropus vampyrus 97.14 0.00e+00 2154.00
IUUC-Pgr-103463 Puccinia graminis 36.70 1.00e-169 590.00
IUUC-Ptt-103716 Puccinia triticina 37.75 6.00e-167 581.00
IUUC-Pte-104360 Pyrenophora teres 36.23 2.00e-151 530.00
IUUC-Pyt-104581 Pyrenophora triticirepentis 35.85 1.00e-149 524.00
IUUC-Rno-105816 Rattus norvegicus 99.35 0.00e+00 2220.00
IUUC-Sce-106230 Saccharomyces cerevisiae 30.07 7.00e-124 438.00
IUUC-Sha-107439 Sarcophilus harrisii 97.67 0.00e+00 2176.00
IUUC-Sja-107690 Schizosaccharomyces japonicus 33.00 3.00e-139 489.00
IUUC-Spo-108019 Schizosaccharomyces pombe 34.72 5.00e-145 508.00
IUUC-Smo-109308 Selaginella moellendorffii 36.07 5.00e-153 535.00
IUUC-Sit-110367 Setaria italica 36.35 1.00e-157 551.00
IUUC-Sly-111774 Solanum lycopersicum 36.69 3.00e-166 579.00
IUUC-Stu-112387 Solanum tuberosum 37.41 1.00e-165 577.00
IUUC-Sar-113685 Sorex araneus 97.96 0.00e+00 2179.00
IUUC-Sbi-114037 Sorghum bicolor 36.87 1.00e-158 554.00
IUUC-Sre-115156 Sporisorium reilianum 36.68 0.00e+00 633.00
IUUC-Ssc-116297 Sus scrofa 98.43 0.00e+00 2207.00
IUUC-Tgu-116767 Taeniopygia guttata 96.03 0.00e+00 2192.00
IUUC-Tru-118208 Takifugu rubripes 92.61 0.00e+00 2090.00
IUUC-Tsy-119277 Tarsius syrichta 87.87 0.00e+00 707.00
IUUC-Tni-119890 Tetraodon nigroviridis 92.79 0.00e+00 2096.00
IUUC-Tca-121501 Theobroma cacao 36.57 1.00e-158 554.00
IUUC-Tre-122169 Trichoderma reesei 33.64 8.00e-154 538.00
IUUC-Tvi-122600 Trichoderma virens 34.15 4.00e-161 562.00
IUUC-Tae-125264 Triticum aestivum 36.02 1.00e-155 544.00
IUUC-Tur-126287 Triticum urartu 35.13 7.00e-149 521.00
IUUC-Tme-127045 Tuber melanosporum 35.44 5.00e-167 582.00
IUUC-Tbe-127696 Tupaia belangeri 88.60 2.00e-160 560.00
IUUC-Ttr-129161 Tursiops truncatus 97.00 0.00e+00 2202.00
IUUC-Uma-129535 Ustilago maydis 36.84 0.00e+00 643.00
IUUC-Vda-129708 Verticillium dahliae 33.09 1.00e-159 557.00
IUUC-Vvi-131048 Vitis vinifera 35.97 5.00e-159 555.00
IUUC-Xtr-132073 Xenopus tropicalis 92.04 0.00e+00 2067.00
IUUC-Xma-133949 Xiphophorus maculatus 92.10 0.00e+00 2108.00
IUUC-Yli-134527 Yarrowia lipolytica 32.72 2.00e-138 487.00
IUUC-Zma-135550 Zea mays 35.07 2.00e-147 517.00
Created Date 25-Jun-2017

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