iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Laf-054369

UUCD1 version

UUC-LoA-00220

Ensembl Protein ID

ENSLAFP00000005167.2

UniProt Accession

G3SXM6; G3SXM6_LOXAF

Protein Name

DCN1-like protein; Defective in cullin neddylation protein 1-like protein

Gene Name

DCUN1D3

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLAFG00000006161.2	ENSLAFT00000006158.2	ENSLAFP00000005167.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/DCUN1	5.30e-84	281.3	87	278

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/DCUN1

   S: 2    skkkleelferYkdpqedligieglekfcedlgvdpediavLvlawkleaatlcefsreefldgltalgcdsieklqeklktleselkd 90
           s ++leelf+rYkd++ed+i++eg+e+fc+dl+vdp++++vL+lawk++aat+c+f+r+ef+dg++a+++dsi+++++++++l  e+k+
   Q: 87   SLQRLEELFKRYKDEREDAILEEGMERFCNDLCVDPTEFRVLLLAWKFQAATMCKFTRKEFFDGCKAISADSIDGICARFPSLLIEAKQ 175
           679************************************************************************************** PP
   S: 91   eqkfkdiYrfafnfakd..kgqksldldtaialwkLllaerefklldawlkfLeee..kkksiskDtWnllLefskviakdlsnYdeeg 175
           e+kfkd+Yrf+f+f++d  +gq+sl++++aialwkL+++++++++ld+wl+fL+e+  ++k+is+DtWn++L+f++vi +dlsnY+e++
   Q: 176  EDKFKDLYRFTFQFGLDseEGQRSLHREIAIALWKLVFTQNNPPVLDQWLHFLTENpsGIKGISRDTWNMFLNFTQVIGPDLSNYSEDE 264
           ***************998899**********************************9889****************************** PP
   S: 176  aWPvliDefveylk 189
           aWP+l+D+fve+++
   Q: 265  AWPSLFDTFVEWEM 278
           ************85 PP

Organism

Loxodonta africana

Protein Sequence
(Fasta)

MGQCVTKCKN PSSTLGSKNG DRDSSSKSQS RRGAGHHEEQ APACGKPGGD ILVNGTKKVE 60
AATDACQLPT SSGDAGREPK SNAEESSLQR LEELFKRYKD EREDAILEEG MERFCNDLCV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGGCCAGT GTGTCACCAA GTGCAAGAAT CCCTCATCAA CCCTGGGCAG TAAGAATGGA 60
GACCGTGACT CCAGCAGCAA GTCACAGAGC AGGCGGGGTG CAGGCCACCA CGAGGAACAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR014764--DCN-prot
IPR005176--PONY_dom

PROSITE

PS51229--DCUN1

Pfam

PF03556--Cullin_binding

Gene Ontology

GO:0048471--C:perinuclear region of cytoplasm
GO:0030308--P:negative regulation of cell growth
GO:0043065--P:positive regulation of apoptotic process
GO:0010332--P:response to gamma radiation
GO:0010225--P:response to UV-C

KEGG

lav:100667815

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001689	Ailuropoda melanoleuca	95.39	1.00e-163	568.00
IUUC-Apl-003497	Anas platyrhynchos	81.91	1.00e-141	495.00
IUUC-Aca-004961	Anolis carolinensis	80.59	3.00e-147	514.00
IUUC-Aor-009902	Aspergillus oryzae	33.83	2.00e-11	61.20
IUUC-Ame-011413	Astyanax mexicanus	64.31	5.00e-102	363.00
IUUC-Bta-013338	Bos taurus	95.07	2.00e-163	568.00
IUUC-Cja-019458	Callithrix jacchus	95.39	3.00e-164	570.00
IUUC-Cfa-020160	Canis familiaris	95.72	2.00e-164	570.00
IUUC-Cpo-021835	Cavia porcellus	95.39	5.00e-155	540.00
IUUC-Csa-023328	Chlorocebus sabaeus	95.72	8.00e-165	572.00
IUUC-Cho-024888	Choloepus hoffmanni	94.70	2.00e-163	567.00
IUUC-Cin-025134	Ciona intestinalis	55.08	2.00e-59	223.00
IUUC-Csv-025904	Ciona savignyi	50.41	3.00e-32	129.00
IUUC-Dre-027780	Danio rerio	64.75	2.00e-96	345.00
IUUC-Dno-028866	Dasypus novemcinctus	95.72	3.00e-163	566.00
IUUC-Dor-030387	Dipodomys ordii	94.08	3.00e-161	560.00
IUUC-Dme-032081	Drosophila melanogaster	49.49	5.00e-49	187.00
IUUC-Eca-033857	Equus caballus	96.05	8.00e-166	575.00
IUUC-Eeu-034825	Erinaceus europaeus	87.50	1.00e-147	515.00
IUUC-Fca-036130	Felis catus	96.05	2.00e-165	574.00
IUUC-Fal-037296	Ficedula albicollis	81.91	6.00e-141	493.00
IUUC-Gmo-039626	Gadus morhua	64.06	2.00e-98	351.00
IUUC-Ggr-039959	Gaeumannomyces graminis	26.64	3.00e-15	76.60
IUUC-Gga-040741	Gallus gallus	81.25	1.00e-138	485.00
IUUC-Gac-042271	Gasterosteus aculeatus	66.91	2.00e-92	332.00
IUUC-Ggo-044727	Gorilla gorilla	95.72	8.00e-165	572.00
IUUC-Hsa-046288	Homo sapiens	95.39	3.00e-164	570.00
IUUC-Itr-049054	Ictidomys tridecemlineatus	95.72	5.00e-174	603.00
IUUC-Lch-050289	Latimeria chalumnae	78.22	2.00e-132	464.00
IUUC-Loc-052455	Lepisosteus oculatus	71.22	9.00e-108	382.00
IUUC-Mcc-055413	Macaca mulatta	76.30	1.00e-117	415.00
IUUC-Meu-056535	Macropus eugenii	85.53	4.00e-152	530.00
IUUC-Mga-059290	Meleagris gallopavo	81.91	7.00e-141	493.00
IUUC-Mmr-060689	Microcebus murinus	95.39	4.00e-164	570.00
IUUC-Mdo-062128	Monodelphis domestica	85.86	6.00e-147	513.00
IUUC-Mmu-064396	Mus musculus	93.75	2.00e-170	590.00
IUUC-Mpu-065926	Mustela putorius furo	95.39	1.00e-163	568.00
IUUC-Mlu-067044	Myotis lucifugus	94.41	6.00e-172	595.00
IUUC-Nle-069346	Nomascus leucogenys	95.72	8.00e-165	572.00
IUUC-Opr-070682	Ochotona princeps	95.72	1.00e-153	535.00
IUUC-Ont-071772	Oreochromis niloticus	67.74	2.00e-101	361.00
IUUC-Oan-072765	Ornithorhynchus anatinus	82.57	1.00e-142	498.00
IUUC-Ocu-074272	Oryctolagus cuniculus	91.03	2.00e-117	414.00
IUUC-Ola-087561	Oryzias latipes	69.10	2.00e-106	378.00
IUUC-Oga-088440	Otolemur garnettii	77.03	4.00e-122	430.00
IUUC-Oar-089403	Ovis aries	95.72	9.00e-165	572.00
IUUC-Ptr-091384	Pan troglodytes	95.72	8.00e-165	572.00
IUUC-Pan-092650	Papio anubis	95.72	8.00e-165	572.00
IUUC-Psi-093806	Pelodiscus sinensis	83.22	2.00e-135	474.00
IUUC-Pma-094196	Petromyzon marinus	56.45	1.00e-87	316.00
IUUC-Pfo-096584	Poecilia formosa	70.36	6.00e-105	373.00
IUUC-Pab-098605	Pongo abelii	95.72	8.00e-165	572.00
IUUC-Pca-100933	Procavia capensis	79.61	4.00e-118	417.00
IUUC-Pva-102172	Pteropus vampyrus	91.86	5.00e-160	556.00
IUUC-Rno-105406	Rattus norvegicus	94.74	4.00e-172	596.00
IUUC-Sha-106531	Sarcophilus harrisii	85.20	1.00e-152	531.00
IUUC-Sar-113051	Sorex araneus	75.33	6.00e-114	403.00
IUUC-Ssc-115555	Sus scrofa	96.05	2.00e-165	574.00
IUUC-Tgu-117178	Taeniopygia guttata	82.24	1.00e-142	498.00
IUUC-Tru-117876	Takifugu rubripes	68.29	6.00e-105	373.00
IUUC-Tsy-118790	Tarsius syrichta	93.67	1.00e-132	465.00
IUUC-Tni-119673	Tetraodon nigroviridis	66.56	1.00e-105	375.00
IUUC-Tbe-127429	Tupaia belangeri	95.39	2.00e-164	570.00
IUUC-Ttr-128467	Tursiops truncatus	96.05	2.00e-165	574.00
IUUC-Vpa-130376	Vicugna pacos	66.18	8.00e-94	336.00
IUUC-Xtr-132134	Xenopus tropicalis	78.91	5.00e-121	426.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence