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Tag Content
UUCD2 ID IUUC-Cin-025674
UUCD1 version UUC-CiI-00504
Ensembl Protein ID ENSCINP00000034692.1
UniProt Accession H2XYF8; H2XYF8_CIOIN
Genbank Protein ID ENSCINP00000034692
Protein Name E3 ubiquitin-protein ligase
Genbank Nucleotide ID EAAA01000694
Gene Name LOC100176189
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSCING00000024656.1 ENSCINT00000033263.1 ENSCINP00000034692.1
Status Unreviewed
Classification
Family Identity E-Value Score Source Orthology
E3 activity/RING/RING 34.88 1.00e-37 153.00 IUUC-Ath-007192
E3 activity/RING/RING 80.63 2.00e-123 438.00 IUUC-Dme-031700
E3 activity/RING/RING 78.01 2.00e-133 472.00 IUUC-Hsa-046357
Active Site
Position(s) Description Evidence
N/A N/A N/A
Organism Ciona intestinalis
Functional Description
(View)

Functional Description


     E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.
 E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.
Protein Sequence
(Fasta)
MSRQSSNIVS VAGNERQVEG MAAGLACASG NELDLASLFE CPVCFDYVLP PILQCQSGHL 60
VCTNCRPKLT CCPTCRGALG NIRNLGMEKV AMTVDFPCKY AASGCEVTLR YIQKPEHEET 120
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Protein Fasta Sequence


>IUUC-Cin-025674|E3,RING|Ciona intestinalis
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Nucleotide Sequence
(Fasta)
AAGCAACGTT AGGATGTAAA AAATAACGTT GCAAATGTAA AATGGACTTA AACTGTTCCT 60
GAGTCATTAA ATCAAAAACA TGAGCAGGCA ATCGTCAAAC ATTGTGAGTG TTGCTGGAAA 120
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Nucleotide Fasta Sequence


>IUUC-Cin-025674|E3,RING|Ciona intestinalis
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Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger
Interpro

IPR018121--7-in-absentia-prot_TRAF-dom
IPR004162--SINA-like
IPR008974--TRAF-like
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR013010--Znf_SIAH
PROSITE

PS50089--ZF_RING_2
PS51081--ZF_SIAH
Pfam

PF03145--Sina
Gene Ontology

GO:0005634--C:nucleus
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0007275--P:multicellular organism development
GO:0006511--P:ubiquitin-dependent protein catabolic process
KEGG cin:100176189
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000061 Aegilops tauschii 35.98 5.00e-42 163.00
IUUC-Aml-001186 Ailuropoda melanoleuca 78.01 4.00e-135 472.00
IUUC-Atr-002857 Amborella trichopoda 37.70 1.00e-45 174.00
IUUC-Apl-003813 Anas platyrhynchos 78.01 3.00e-135 472.00
IUUC-Aca-005014 Anolis carolinensis 78.01 2.00e-135 473.00
IUUC-Aly-006522 Arabidopsis lyrata 35.27 2.00e-39 154.00
IUUC-Ath-007192 Arabidopsis thaliana 34.88 5.00e-39 153.00
IUUC-Ame-011196 Astyanax mexicanus 78.37 2.00e-135 473.00
IUUC-Bta-012887 Bos taurus 78.01 4.00e-135 472.00
IUUC-Bdi-014200 Brachypodium distachyon 35.98 7.00e-43 166.00
IUUC-Bol-016263 Brassica oleracea 34.15 8.00e-40 155.00
IUUC-Bra-017336 Brassica rapa 34.94 6.00e-41 159.00
IUUC-Cel-018320 Caenorhabditis elegans 66.28 1.00e-107 382.00
IUUC-Cja-019796 Callithrix jacchus 78.01 4.00e-135 472.00
IUUC-Cfa-020642 Canis familiaris 78.01 8.00e-136 474.00
IUUC-Cpo-022348 Cavia porcellus 78.01 6.00e-135 471.00
IUUC-Csa-023974 Chlorocebus sabaeus 78.01 4.00e-135 472.00
IUUC-Cho-024933 Choloepus hoffmanni 83.60 5.00e-128 448.00
IUUC-Csv-026233 Ciona savignyi 98.03 2.00e-152 530.00
IUUC-Dre-028041 Danio rerio 78.37 2.00e-135 473.00
IUUC-Dno-029764 Dasypus novemcinctus 78.01 3.00e-135 473.00
IUUC-Dor-030489 Dipodomys ordii 83.06 7.00e-95 337.00
IUUC-Dme-031700 Drosophila melanogaster 81.85 3.00e-118 416.00
IUUC-Ete-032946 Echinops telfairi 84.00 2.00e-128 449.00
IUUC-Eca-033536 Equus caballus 78.01 3.00e-135 472.00
IUUC-Eeu-035314 Erinaceus europaeus 77.44 1.00e-125 441.00
IUUC-Fca-035362 Felis catus 78.01 3.00e-135 473.00
IUUC-Fal-037487 Ficedula albicollis 78.01 4.00e-135 472.00
IUUC-Gmo-039091 Gadus morhua 78.35 2.00e-124 437.00
IUUC-Gga-040269 Gallus gallus 78.01 3.00e-135 472.00
IUUC-Gac-042282 Gasterosteus aculeatus 78.72 2.00e-135 473.00
IUUC-Gma-042926 Glycine max 32.50 2.00e-41 161.00
IUUC-Ggo-045444 Gorilla gorilla 78.01 4.00e-135 472.00
IUUC-Hsa-046357 Homo sapiens 78.01 4.00e-135 472.00
IUUC-Hvu-047574 Hordeum vulgare 35.98 3.00e-42 163.00
IUUC-Itr-048046 Ictidomys tridecemlineatus 78.01 6.00e-135 471.00
IUUC-Lch-049504 Latimeria chalumnae 78.01 3.00e-135 472.00
IUUC-Lpe-050879 Leersia perrieri 36.14 1.00e-40 159.00
IUUC-Loc-052191 Lepisosteus oculatus 78.37 2.00e-135 473.00
IUUC-Laf-053668 Loxodonta africana 78.01 3.00e-135 472.00
IUUC-Mcc-054640 Macaca mulatta 78.01 4.00e-135 472.00
IUUC-Meu-055922 Macropus eugenii 82.00 6.00e-125 438.00
IUUC-Mtr-058747 Medicago truncatula 33.93 1.00e-43 168.00
IUUC-Mga-059503 Meleagris gallopavo 78.01 3.00e-135 473.00
IUUC-Mvi-060329 Microbotryum violaceum 37.50 2.10e-01 29.60
IUUC-Mmr-060794 Microcebus murinus 78.01 6.00e-135 471.00
IUUC-Mdo-061971 Monodelphis domestica 82.40 1.00e-126 444.00
IUUC-Mmu-063876 Mus musculus 78.72 6.00e-136 475.00
IUUC-Mac-065014 Musa acuminata 36.59 4.00e-41 160.00
IUUC-Mpu-066488 Mustela putorius furo 78.01 4.00e-135 472.00
IUUC-Mlu-067207 Myotis lucifugus 78.01 2.00e-135 473.00
IUUC-Nle-069706 Nomascus leucogenys 78.01 4.00e-135 472.00
IUUC-Opr-070341 Ochotona princeps 54.90 6.00e-49 186.00
IUUC-Ont-071849 Oreochromis niloticus 78.72 1.00e-135 473.00
IUUC-Oan-073701 Ornithorhynchus anatinus 53.85 5.00e-49 186.00
IUUC-Ocu-074876 Oryctolagus cuniculus 78.01 6.00e-135 471.00
IUUC-Oba-075789 Oryza barthii 35.66 6.00e-43 166.00
IUUC-Obr-076037 Oryza brachyantha 35.55 1.00e-42 165.00
IUUC-Ogl-077148 Oryza glaberrima 35.66 6.00e-43 166.00
IUUC-Ogu-078042 Oryza glumaepatula 35.66 5.00e-43 166.00
IUUC-Oin-079325 Oryza indica 35.66 5.00e-43 166.00
IUUC-Olo-080244 Oryza longistaminata 35.66 9.00e-43 166.00
IUUC-Ome-081318 Oryza meridionalis 36.00 6.00e-41 159.00
IUUC-Oni-082163 Oryza nivara 35.66 6.00e-43 166.00
IUUC-Opu-084065 Oryza punctata 36.40 3.00e-41 160.00
IUUC-Oru-084833 Oryza rufipogon 35.66 5.00e-43 166.00
IUUC-Osa-085316 Oryza sativa 35.66 5.00e-43 166.00
IUUC-Ola-086814 Oryzias latipes 78.72 2.00e-135 473.00
IUUC-Oga-088399 Otolemur garnettii 78.01 6.00e-135 471.00
IUUC-Oar-089323 Ovis aries 78.01 4.00e-135 472.00
IUUC-Ptr-090692 Pan troglodytes 78.01 3.00e-135 472.00
IUUC-Pan-092012 Papio anubis 78.01 4.00e-135 472.00
IUUC-Psi-093687 Pelodiscus sinensis 78.01 2.00e-135 473.00
IUUC-Pma-094387 Petromyzon marinus 76.68 4.00e-132 462.00
IUUC-Ppa-095212 Physcomitrella patens 35.37 3.00e-41 160.00
IUUC-Pfo-097134 Poecilia formosa 78.72 2.00e-135 473.00
IUUC-Pab-097555 Pongo abelii 78.01 4.00e-135 472.00
IUUC-Pop-099563 Populus trichocarpa 35.20 7.00e-45 172.00
IUUC-Pca-100328 Procavia capensis 83.20 4.00e-125 439.00
IUUC-Ppe-101760 Prunus persica 33.56 9.00e-43 165.00
IUUC-Pva-102368 Pteropus vampyrus 89.09 3.00e-57 213.00
IUUC-Rno-104866 Rattus norvegicus 78.37 2.00e-135 473.00
IUUC-Sha-106547 Sarcophilus harrisii 78.01 2.00e-135 473.00
IUUC-Smo-109412 Selaginella moellendorffii 34.15 2.00e-39 154.00
IUUC-Sit-110245 Setaria italica 35.20 8.00e-42 162.00
IUUC-Sly-111117 Solanum lycopersicum 32.02 2.00e-40 158.00
IUUC-Stu-112474 Solanum tuberosum 34.94 9.00e-42 162.00
IUUC-Sbi-114035 Sorghum bicolor 35.20 4.00e-42 163.00
IUUC-Ssc-116441 Sus scrofa 84.00 3.00e-128 449.00
IUUC-Tgu-116579 Taeniopygia guttata 78.01 3.00e-135 472.00
IUUC-Tru-118250 Takifugu rubripes 84.11 1.00e-132 463.00
IUUC-Tsy-119548 Tarsius syrichta 81.82 1.00e-61 227.00
IUUC-Tni-120488 Tetraodon nigroviridis 78.01 1.00e-131 460.00
IUUC-Tca-121228 Theobroma cacao 35.74 8.00e-43 166.00
IUUC-Tae-123647 Triticum aestivum 35.98 5.00e-42 163.00
IUUC-Tur-126049 Triticum urartu 34.40 2.00e-40 157.00
IUUC-Ttr-129166 Tursiops truncatus 84.94 9.00e-122 428.00
IUUC-Vpa-130799 Vicugna pacos 88.82 5.00e-92 328.00
IUUC-Vvi-131451 Vitis vinifera 33.71 2.00e-41 161.00
IUUC-Xtr-132553 Xenopus tropicalis 78.37 2.00e-135 473.00
IUUC-Xma-133670 Xiphophorus maculatus 78.72 2.00e-135 473.00
Created Date 25-Jun-2017

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