iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Fox-038037

Ensembl Protein ID

FOXG_11358P0

UniProt Accession

A0A0D2Y504; A0A0D2Y504_FUSO4

Genbank Protein ID

KNB11473.1; KNB11474.1

Protein Name

NEDD8-activating enzyme E1 regulatory subunit

Genbank Nucleotide ID

DS231710; DS231710

Gene Name

FOXG_11358

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
FOXG_11358	FOXG_11358T0	FOXG_11358P0

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E1	5.70e-59	200.1	22	524

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

   S: 1    YDRQirlwGeeaqeklksakvllv..GagglGcEllKnLvlaGvgsitvvDmdtvevsnlnrqFLfraedvgksKAevaaealkelnpdvnveahee 95
           YDRQ+rlw + +q++l+sa++llv  Gag++G+E+lKnLvl G+g +t+ D++ v+ ++l+ +F+++++  gks+Ae++ ++l elnp v++e + +
   Q: 22   YDRQLRLWAASGQAALESANILLVnsGAGTVGVETLKNLVLPGIGRFTIADQNAVTHQDLGVNFFVDDSWLGKSRAEACTNFLLELNPEVQGEWYPK 118
           ***********************8557999*****************************************************************99 PP
   S: 96   siteleeeivFfk...kfdvVvlal.dnrearrkvnrlclnarvpliesgtlGllGqvrviikgltecyscsd.....dppqktiPfctlketpn.. 181
             +e  + +++++   +f++++ al  + ++   + +  +++++p+i + + G++++ ++ ++g   + + ++      ++++ +P+++l e+ +  
   Q: 119  TQDEYFHLDHLLSsspTFTMILYALpLPHDQVQLIQNYSHQHKIPIIAVHSVGYYSYFKTTLPGTFPIVDTHPdetatTDLRLLAPWPELLEFSQsm 215
           999998888855533379***99984677788889****************************9755555554499999**************7777 PP
   S: 182  .........aaehtiewavlfnklleeeageeevlekldseekeegkdkvkselks....edeenfeeaieiavkafakttins.ikqllksfecdi 264
                     ++ +++++v++ ++le+++++++++ ++++ +k+++++ v++++++      eenfeeai++++k+  + + +s  +q++++ ++d+
   Q: 216  tenidnldsHEHGHLPMVVILLHYLEQWKEAHDGAYPTSYIDKTAFRKTVSEAMRTdnpeGGEENFEEAIAAVMKHVVTPSLPSsLRQVFDYVHQDP 312
           777777777999999999**************************************66655689***************999999**********99 PP
   S: 265  vtkskspfwv....................................................................sfcsnaealq......... 284
             + +s fwv                                                                     fc+na  ++         
   Q: 313  -EEINSGFWViteavkrfydehgrlpvpgglpdmkaqsnvyiklqniykerarqdvgqvletarslpggqdvdpeqveLFCKNAPFIKlinapgdkt 408
           .99999************************************************************************6666666666666665555 PP
   S: 285  .......vpekvekdeevvkasap.lylllralerfekkkgrkpgelsfekdddsavdlvtaaanlraeslgiepkldddlikeiagniipaiattn 373
                  ++e +++++ +++ ++  l+l  + l ++++ ++++        ++d+++ ++ +aa  +a++ +   k + + +++ ag   ++++ ++
   Q: 409  tsldklvEQELANDEMSAFAGPEMpLSLVPLYLALLATSNTKTA-------SADEIMGFIGKAAP-KATENERY-KKTAQEVERAAG---GELHNIS 493
           55444447888888888888887797777777888888777764.......7889*********6.44444444.489999999988...9****** PP
   S: 374  avvgGlaaqEviKvvsgkfeplknfflfdae 404
           a  gG++aqE+iK+++++++p++n+ +fd++
   Q: 494  ALTGGMVAQEMIKIITKQYVPIENTCIFDGI 524
           ****************************986 PP

Organism

Fusarium oxysporum

Functional Description
(View)

Regulatory subunit of the dimeric UBA3-ULA1 E1 enzyme.

Protein Sequence
(Fasta)

MADVMIQTPP VLQGPSEKER KYDRQLRLWA ASGQAALESA NILLVNSGAG TVGVETLKNL 60
VLPGIGRFTI ADQNAVTHQD LGVNFFVDDS WLGKSRAEAC TNFLLELNPE VQGEWYPKTQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ACCCACTCCA TTCGAGAGCT TCATCAATAG CATCTATACC AGCAGTCTCT CACATCTTAT 60
CGAGGGTCTC GCGGCACTCG TTTATCCGAA GTCCGTCTGC TCGCTGTGTG ACTTCTTACA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR030667--APP-BP1
IPR016040--NAD(P)-bd_dom
IPR000594--ThiF_NAD_FAD-bd

Pfam

PF00899--ThiF

Gene Ontology

GO:0019781--F:NEDD8 activating enzyme activity
GO:0045116--P:protein neddylation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000764	Aegilops tauschii	32.05	8.00e-73	266.00
IUUC-Aml-002333	Ailuropoda melanoleuca	34.18	7.00e-78	282.00
IUUC-Atr-002644	Amborella trichopoda	31.51	2.00e-59	221.00
IUUC-Apl-003446	Anas platyrhynchos	33.03	4.00e-68	250.00
IUUC-Aca-004450	Anolis carolinensis	33.81	1.00e-75	275.00
IUUC-Aly-005466	Arabidopsis lyrata	31.58	6.00e-68	249.00
IUUC-Ath-006692	Arabidopsis thaliana	31.45	1.00e-68	251.00
IUUC-Ago-007900	Ashbya gossypii	25.29	2.00e-34	137.00
IUUC-Acl-008333	Aspergillus clavatus	44.21	2.00e-125	440.00
IUUC-Afl-008529	Aspergillus flavus	44.01	2.00e-124	437.00
IUUC-Afu-009071	Aspergillus fumigatus	45.80	8.00e-128	448.00
IUUC-Ani-009443	Aspergillus nidulans	44.62	8.00e-122	428.00
IUUC-Ang-009669	Aspergillus niger	46.07	2.00e-138	484.00
IUUC-Aor-009914	Aspergillus oryzae	44.19	1.00e-124	437.00
IUUC-Ate-010450	Aspergillus terreus	44.27	5.00e-126	442.00
IUUC-Ame-011183	Astyanax mexicanus	30.55	4.00e-70	256.00
IUUC-Bgr-012111	Blumeria graminis	52.77	1.00e-153	534.00
IUUC-Bta-012583	Bos taurus	34.96	4.00e-78	283.00
IUUC-Bci-013892	Botrytis cinerea	59.85	1.00e-175	607.00
IUUC-Bdi-014592	Brachypodium distachyon	32.42	2.00e-69	254.00
IUUC-Bol-016399	Brassica oleracea	32.12	4.00e-70	256.00
IUUC-Bra-017506	Brassica rapa	30.56	1.00e-63	235.00
IUUC-Cel-018456	Caenorhabditis elegans	27.42	4.00e-48	184.00
IUUC-Cja-020007	Callithrix jacchus	33.87	2.00e-77	281.00
IUUC-Cfa-020324	Canis familiaris	34.30	9.00e-79	285.00
IUUC-Cpo-022248	Cavia porcellus	33.87	1.00e-44	172.00
IUUC-Csa-023149	Chlorocebus sabaeus	30.48	5.00e-53	200.00
IUUC-Cho-024537	Choloepus hoffmanni	26.08	5.00e-37	146.00
IUUC-Cin-025763	Ciona intestinalis	32.53	6.00e-75	273.00
IUUC-Csv-026113	Ciona savignyi	34.08	5.00e-79	286.00
IUUC-Cgl-026428	Colletotrichum gloeosporioides	59.13	0.00e+00	626.00
IUUC-Cne-026884	Cryptococcus neoformans	29.84	4.00e-53	200.00
IUUC-Dre-028140	Danio rerio	32.24	1.00e-72	265.00
IUUC-Dno-030033	Dasypus novemcinctus	35.90	5.00e-70	256.00
IUUC-Dor-030513	Dipodomys ordii	57.43	2.00e-26	112.00
IUUC-Dse-031536	Dothistroma septosporum	42.71	3.00e-123	433.00
IUUC-Dme-031683	Drosophila melanogaster	35.17	1.00e-72	265.00
IUUC-Ete-032420	Echinops telfairi	30.15	1.00e-58	218.00
IUUC-Eca-033992	Equus caballus	30.00	7.00e-50	189.00
IUUC-Eeu-034713	Erinaceus europaeus	57.14	7.00e-27	113.00
IUUC-Fca-036548	Felis catus	34.41	1.00e-78	285.00
IUUC-Fal-037600	Ficedula albicollis	32.40	3.00e-64	237.00
IUUC-Fso-038387	Fusarium solani	82.36	0.00e+00	933.00
IUUC-Gmo-038562	Gadus morhua	32.65	1.00e-68	251.00
IUUC-Ggr-040005	Gaeumannomyces graminis	62.03	0.00e+00	676.00
IUUC-Gga-041129	Gallus gallus	33.94	2.00e-71	261.00
IUUC-Gac-042558	Gasterosteus aculeatus	32.79	1.00e-71	262.00
IUUC-Gma-043610	Glycine max	30.85	8.00e-64	236.00
IUUC-Ggo-045611	Gorilla gorilla	34.41	1.00e-77	282.00
IUUC-Hsa-046563	Homo sapiens	34.59	2.00e-79	287.00
IUUC-Hvu-047790	Hordeum vulgare	28.79	2.00e-42	164.00
IUUC-Itr-048066	Ictidomys tridecemlineatus	34.23	3.00e-77	280.00
IUUC-Kpa-049309	Komagataella pastoris	32.51	8.00e-67	246.00
IUUC-Lch-050038	Latimeria chalumnae	31.79	4.00e-70	256.00
IUUC-Lpe-051535	Leersia perrieri	28.63	4.00e-49	187.00
IUUC-Loc-051917	Lepisosteus oculatus	30.05	1.00e-58	218.00
IUUC-Lma-053112	Leptosphaeria maculans	43.28	5.00e-134	469.00
IUUC-Laf-053690	Loxodonta africana	34.70	2.00e-80	291.00
IUUC-Mcc-055117	Macaca mulatta	33.81	4.00e-75	273.00
IUUC-Meu-056761	Macropus eugenii	27.80	2.00e-47	181.00
IUUC-Mor-057230	Magnaporthe oryzae	61.65	0.00e+00	691.00
IUUC-Mpo-057514	Magnaporthe poae	63.21	0.00e+00	664.00
IUUC-Mtr-058551	Medicago truncatula	31.14	5.00e-63	233.00
IUUC-Mla-059183	Melampsora laricipopulina	34.10	1.00e-75	275.00
IUUC-Mga-060144	Meleagris gallopavo	32.21	2.00e-67	248.00
IUUC-Mvi-060221	Microbotryum violaceum	34.95	1.00e-77	281.00
IUUC-Mmr-061325	Microcebus murinus	33.15	2.00e-74	271.00
IUUC-Mdo-062532	Monodelphis domestica	34.05	1.00e-77	282.00
IUUC-Mmu-063956	Mus musculus	34.70	2.00e-79	287.00
IUUC-Mac-064521	Musa acuminata	32.16	5.00e-69	253.00
IUUC-Mpu-066716	Mustela putorius furo	35.87	2.00e-70	258.00
IUUC-Mlu-067459	Myotis lucifugus	34.35	1.00e-77	282.00
IUUC-Nfi-068245	Neosartorya fischeri	46.01	1.00e-126	444.00
IUUC-Ncr-068910	Neurospora crassa	59.41	0.00e+00	668.00
IUUC-Nle-070034	Nomascus leucogenys	32.78	1.00e-69	255.00
IUUC-Opr-070552	Ochotona princeps	36.12	1.00e-59	221.00
IUUC-Ont-071426	Oreochromis niloticus	33.03	5.00e-74	270.00
IUUC-Oan-073389	Ornithorhynchus anatinus	29.18	6.00e-45	173.00
IUUC-Ocu-074911	Oryctolagus cuniculus	34.59	8.00e-80	289.00
IUUC-Oba-075437	Oryza barthii	31.38	1.00e-61	228.00
IUUC-Obr-076684	Oryza brachyantha	31.73	7.00e-57	213.00
IUUC-Ogl-077170	Oryza glaberrima	31.38	1.00e-61	228.00
IUUC-Ogu-078844	Oryza glumaepatula	29.36	2.00e-52	197.00
IUUC-Oin-079105	Oryza indica	31.38	1.00e-61	229.00
IUUC-Olo-080943	Oryza longistaminata	29.15	9.00e-47	179.00
IUUC-Oni-082891	Oryza nivara	30.46	4.00e-56	210.00
IUUC-Opu-083457	Oryza punctata	31.56	3.00e-61	227.00
IUUC-Oru-084960	Oryza rufipogon	29.09	9.00e-47	179.00
IUUC-Osa-085358	Oryza sativa	31.19	3.00e-61	227.00
IUUC-Ola-086420	Oryzias latipes	31.33	2.00e-44	171.00
IUUC-Olu-087625	Ostreococcus lucimarinus	24.09	8.00e-39	152.00
IUUC-Oga-088810	Otolemur garnettii	34.11	2.00e-78	284.00
IUUC-Oar-089196	Ovis aries	34.23	2.00e-76	278.00
IUUC-Ptr-090617	Pan troglodytes	34.41	1.00e-78	285.00
IUUC-Pan-092761	Papio anubis	34.41	2.00e-79	288.00
IUUC-Psi-093191	Pelodiscus sinensis	32.54	4.00e-69	253.00
IUUC-Pma-094380	Petromyzon marinus	35.96	5.00e-67	246.00
IUUC-Pno-095084	Phaeosphaeria nodorum	40.86	2.00e-115	408.00
IUUC-Ppa-095798	Physcomitrella patens	30.69	2.00e-64	238.00
IUUC-Pfo-096467	Poecilia formosa	32.17	1.00e-68	251.00
IUUC-Pab-098255	Pongo abelii	35.78	2.00e-70	258.00
IUUC-Pop-099871	Populus trichocarpa	32.91	4.00e-69	253.00
IUUC-Pca-100807	Procavia capensis	37.82	3.00e-29	120.00
IUUC-Ppe-101280	Prunus persica	30.76	1.00e-66	245.00
IUUC-Pva-102333	Pteropus vampyrus	32.91	1.00e-70	258.00
IUUC-Pgr-103401	Puccinia graminis	30.07	7.00e-66	243.00
IUUC-Ptt-103889	Puccinia triticina	28.96	1.00e-59	222.00
IUUC-Pte-104355	Pyrenophora teres	42.93	6.00e-131	459.00
IUUC-Pyt-104545	Pyrenophora triticirepentis	43.55	6.00e-131	459.00
IUUC-Rno-105810	Rattus norvegicus	33.45	4.00e-77	280.00
IUUC-Sce-106397	Saccharomyces cerevisiae	24.00	2.00e-25	108.00
IUUC-Sha-106770	Sarcophilus harrisii	40.21	6.00e-50	188.00
IUUC-Sja-107926	Schizosaccharomyces japonicus	31.73	4.00e-67	247.00
IUUC-Spo-108276	Schizosaccharomyces pombe	32.17	3.00e-64	237.00
IUUC-Ssl-108387	Sclerotinia sclerotiorum	59.51	0.00e+00	639.00
IUUC-Smo-109296	Selaginella moellendorffii	30.45	1.00e-65	242.00
IUUC-Sit-110157	Setaria italica	31.27	1.00e-69	255.00
IUUC-Sly-111105	Solanum lycopersicum	30.54	4.00e-63	233.00
IUUC-Stu-112469	Solanum tuberosum	30.52	1.00e-63	235.00
IUUC-Sar-113083	Sorex araneus	26.52	6.00e-40	156.00
IUUC-Sbi-113813	Sorghum bicolor	31.28	5.00e-70	256.00
IUUC-Sre-115058	Sporisorium reilianum	34.96	1.00e-59	222.00
IUUC-Tgu-116772	Taeniopygia guttata	33.21	1.00e-67	248.00
IUUC-Tru-118686	Takifugu rubripes	32.43	4.00e-73	266.00
IUUC-Tsy-119111	Tarsius syrichta	37.50	9.00e-42	162.00
IUUC-Tni-120231	Tetraodon nigroviridis	30.63	3.00e-61	227.00
IUUC-Tca-121491	Theobroma cacao	31.23	3.00e-61	227.00
IUUC-Tre-122103	Trichoderma reesei	66.29	0.00e+00	746.00
IUUC-Tvi-122672	Trichoderma virens	66.60	0.00e+00	728.00
IUUC-Tae-125316	Triticum aestivum	31.43	1.00e-72	265.00
IUUC-Tur-126487	Triticum urartu	31.28	3.00e-68	250.00
IUUC-Tme-127097	Tuber melanosporum	39.26	1.00e-94	338.00
IUUC-Ttr-128465	Tursiops truncatus	32.74	4.00e-66	243.00
IUUC-Uma-129645	Ustilago maydis	35.10	6.00e-61	226.00
IUUC-Vda-129989	Verticillium dahliae	54.63	1.00e-161	561.00
IUUC-Vpa-130529	Vicugna pacos	33.33	4.00e-71	260.00
IUUC-Vvi-131059	Vitis vinifera	31.47	6.00e-65	239.00
IUUC-Xtr-132002	Xenopus tropicalis	33.46	5.00e-76	276.00
IUUC-Xma-133930	Xiphophorus maculatus	32.52	1.00e-70	258.00
IUUC-Yli-134505	Yarrowia lipolytica	35.11	2.00e-85	308.00
IUUC-Zma-135895	Zea mays	31.05	1.00e-68	251.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence