iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Xtr-132060

Ensembl Protein ID

ENSXETP00000012700.3

UniProt Accession

F6VRL8; F6VRL8_XENTR

Genbank Protein ID

ENSXETP00000012700

Protein Name

LLGL1, scribble cell polarity complex component

Genbank Nucleotide ID

AAMC01050878

Gene Name

llgl1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSXETG00000005768.3	ENSXETT00000012700.3	ENSXETP00000012700.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	5.90e-07	29.8	425	459

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 8    claf............sd.tllvsGsdDgtikvWD 29
           ++++               +ll++G  Dgt++ WD
   Q: 425  SVNWpidggrnlaeepAQrGLLLTGHEDGTVRFWD 459
           566666655555555412378************** PP

Organism

Xenopus tropicalis

Protein Sequence
(Fasta)

MMKFRFRRQG HDPQREKIKQ ELFAFNKTVE HGFPNQPSSL AFDPLLRIMA IGAKSGAVKI 60
YGAPGVEFTG LHKDTATVTQ MHFLPGQGRL LSLLDDNTMH LWELQQKDGS SHLEETRSFL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGATGAAGT TTAGGTTCAG GCGGCAGGGC CATGACCCGC AGAGGGAGAA GATAAAGCAG 60
GAACTGTTTG CCTTCAACAA GGTGGGTGTT GGTTGTGCGG GGAGCCCTAG TGCGGCTGTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR000664--Lethal2_giant
IPR013577--LLGL2
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2

Pfam

PF08366--LLGL

PRINTS

PR00962--LETHAL2GIANT

SMART

SM00320--WD40

Gene Ontology

GO:0016323--C:basolateral plasma membrane
GO:0005737--C:cytoplasm
GO:0005886--C:plasma membrane
GO:0005096--F:GTPase activator activity
GO:0017137--F:Rab GTPase binding
GO:0003407--P:neural retina development
GO:0048919--P:posterior lateral line neuromast development
GO:0017157--P:regulation of exocytosis
GO:0008593--P:regulation of Notch signaling pathway
GO:0050708--P:regulation of protein secretion

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001841	Ailuropoda melanoleuca	68.54	0.00e+00	1337.00
IUUC-Aca-005314	Anolis carolinensis	77.20	0.00e+00	1572.00
IUUC-Aly-005770	Arabidopsis lyrata	23.09	8.00e-16	79.70
IUUC-Ath-007643	Arabidopsis thaliana	22.90	2.00e-15	78.20
IUUC-Ame-011869	Astyanax mexicanus	71.96	0.00e+00	1534.00
IUUC-Bta-013086	Bos taurus	68.84	0.00e+00	1452.00
IUUC-Cja-019964	Callithrix jacchus	70.76	0.00e+00	1405.00
IUUC-Cfa-021081	Canis familiaris	70.63	0.00e+00	1435.00
IUUC-Cpo-022226	Cavia porcellus	69.78	0.00e+00	1329.00
IUUC-Csa-023680	Chlorocebus sabaeus	70.62	0.00e+00	1433.00
IUUC-Cin-025693	Ciona intestinalis	47.83	0.00e+00	768.00
IUUC-Csv-025981	Ciona savignyi	48.85	0.00e+00	884.00
IUUC-Cgl-026432	Colletotrichum gloeosporioides	22.83	1.00e-07	52.40
IUUC-Dre-027684	Danio rerio	72.77	0.00e+00	1519.00
IUUC-Dor-030545	Dipodomys ordii	69.87	0.00e+00	1425.00
IUUC-Ete-033043	Echinops telfairi	67.84	3.00e-174	605.00
IUUC-Eca-034305	Equus caballus	69.90	0.00e+00	1384.00
IUUC-Fca-035636	Felis catus	70.26	0.00e+00	1372.00
IUUC-Fal-037109	Ficedula albicollis	74.90	0.00e+00	1552.00
IUUC-Gmo-039657	Gadus morhua	69.01	0.00e+00	1020.00
IUUC-Gga-040497	Gallus gallus	74.77	0.00e+00	1600.00
IUUC-Gac-041546	Gasterosteus aculeatus	66.36	0.00e+00	1381.00
IUUC-Gma-043398	Glycine max	26.29	2.00e-14	75.10
IUUC-Ggo-045291	Gorilla gorilla	70.52	0.00e+00	1406.00
IUUC-Hsa-046004	Homo sapiens	69.88	0.00e+00	1409.00
IUUC-Itr-048031	Ictidomys tridecemlineatus	68.42	0.00e+00	1396.00
IUUC-Lch-049832	Latimeria chalumnae	72.35	0.00e+00	1426.00
IUUC-Loc-052641	Lepisosteus oculatus	74.95	0.00e+00	1575.00
IUUC-Laf-054218	Loxodonta africana	68.84	0.00e+00	1299.00
IUUC-Mcc-055013	Macaca mulatta	70.34	0.00e+00	1427.00
IUUC-Mtr-058362	Medicago truncatula	25.35	1.00e-12	68.90
IUUC-Mla-058927	Melampsora laricipopulina	28.17	2.00e-04	42.00
IUUC-Mga-060026	Meleagris gallopavo	71.54	0.00e+00	1437.00
IUUC-Mdo-062135	Monodelphis domestica	77.84	0.00e+00	1617.00
IUUC-Mmu-063168	Mus musculus	70.65	0.00e+00	1435.00
IUUC-Mpu-066685	Mustela putorius furo	69.52	0.00e+00	1384.00
IUUC-Mlu-067389	Myotis lucifugus	70.18	0.00e+00	1466.00
IUUC-Opr-070896	Ochotona princeps	69.14	0.00e+00	1400.00
IUUC-Ont-071498	Oreochromis niloticus	67.01	0.00e+00	1345.00
IUUC-Oan-073365	Ornithorhynchus anatinus	75.89	0.00e+00	1528.00
IUUC-Opu-083377	Oryza punctata	32.56	8.00e-04	39.70
IUUC-Ola-086914	Oryzias latipes	64.45	0.00e+00	1334.00
IUUC-Oga-088401	Otolemur garnettii	73.70	0.00e+00	1420.00
IUUC-Oar-089232	Ovis aries	67.24	0.00e+00	1412.00
IUUC-Ptr-090647	Pan troglodytes	70.05	0.00e+00	1356.00
IUUC-Pan-092339	Papio anubis	70.52	0.00e+00	1429.00
IUUC-Psi-093016	Pelodiscus sinensis	67.20	0.00e+00	1248.00
IUUC-Pfo-096941	Poecilia formosa	68.36	0.00e+00	1400.00
IUUC-Pab-098102	Pongo abelii	70.54	0.00e+00	1391.00
IUUC-Pop-099276	Populus trichocarpa	32.56	2.00e-09	58.20
IUUC-Pva-102768	Pteropus vampyrus	69.87	0.00e+00	1496.00
IUUC-Pte-104412	Pyrenophora teres	22.50	1.00e-10	62.00
IUUC-Pyt-104770	Pyrenophora triticirepentis	22.31	1.00e-10	62.00
IUUC-Rno-105033	Rattus norvegicus	71.33	0.00e+00	1496.00
IUUC-Sar-113145	Sorex araneus	68.55	0.00e+00	867.00
IUUC-Tru-118539	Takifugu rubripes	69.73	0.00e+00	1345.00
IUUC-Tsy-119013	Tarsius syrichta	64.55	0.00e+00	700.00
IUUC-Tca-121612	Theobroma cacao	21.78	2.00e-16	81.30
IUUC-Ttr-128232	Tursiops truncatus	68.11	0.00e+00	1371.00
IUUC-Vvi-131379	Vitis vinifera	20.89	2.00e-13	72.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence