iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Bta-013475

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

DAAA02048546

Gene Name

WSB1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSBTAG00000005008.4	ENSBTAT00000006593.4	ENSBTAP00000006593.4

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box	1.90e-15	56.6	375	420
E3 adaptor/Cullin RING/DCX/DWD	6.90e-33	111.4	169	203
UBD/Beta-Prp	1.50e-48	165.6	135	378

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box

   S: 2    sklwllrseprSLqhLCRlaIrrclgsqrlkaidkLPLPksLkdYLlye 50
           +++w ++++++SLqhLCR++Irr +++q++   ++LP P++  ++L+y+
   Q: 375  VYFWATPRQVPSLQHLCRMSIRRVMPTQEV---QELPVPSKVLEFLSYR 420
           689************************999...**************96 PP

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd..tllvsGsdDgtikvWDlrtg 33
           Ht+ v++l f +d   +lvs+s+D+t++vWDl+++
   Q: 169  HTEVVRDLTFaPDgsLILVSASRDKTLRVWDLKDD 203
           9**********8865668*************9987 PP

UBD/Beta-Prp

   S: 17   kfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgk.ilvtgseDrtikvwdls.tgkcvhtlkghedsvlslsfs 103
            f +d+ llatg  +g+ik+wdv tgkll  l +h++ v++++f pdg+ ilv++s+D+t++vwdl+ +g ++ +l+gh++ v+s++fs
   Q: 135  RFGQDQLLLATGLNNGRIKIWDVYTGKLLLNLVDHTEVVRDLTFAPDGSlILVSASRDKTLRVWDLKdDGNMMKVLRGHQNWVYSCAFS 223
           5678999***********************************************************9799******************* PP
   S: 104  psgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtl............tgght 180
           p+++ l s ++ + + +w++++++ ++  l+gh++ v    ++pdg ll+++s+D+ v +Wd  tg +l ++             g+++
   Q: 224  PDSSMLCSVGASKAVFLWNMDKYTMIR-KLEGHHHDVVACDFSPDGALLATASYDTRVYIWDPHTGAILMEFghlfppptpifaGGAND 311
           ***************************.9******************************************************9888** PP
   S: 181  dsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsiriW 249
           + v+s+sf+++g +++s ++d+ v++w + +      + +  +n ++ +fs ++  l+ g++Dgs+++W
   Q: 312  RWVRSVSFSHDGLHVASLADDKMVRFWRIDED--YPVQVAPLSNGLCCAFSTDGSVLAAGTHDGSVYFW 378
           *****************************888..68899****************************** PP

Organism

Bos taurus

Protein Sequence
(Fasta)

MASFPPRVNE KEIVRSRTIG ELLAPAAPFD KKCGRENWTV AFAPDGSYFA WSQGHRTVKL 60
VPWSQCLKNF LLHGTKNITN SSSLRLSRQN SDGGQKNKPR EHIIDCGDIV WSLAFGSSVP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTCGGCGCTC GCCTTTAGCC TCTCTGTCGT TGCGTCCACA TCGCGCCCCC GGAATCAGAC 60
GGTATCCCAT AGATGGCCAG CTTTCCCCCG AGGGTCAACG AGAAAGAGAT CGGTGAGGAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR027295--Quinoprotein_ADH-like_fam
IPR001496--SOCS_box
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS50225--SOCS
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF07525--SOCS_box
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00253--SOCS
SM00969--SOCS_box
SM00320--WD40

Gene Ontology

GO:0005622--C:intracellular
GO:0035556--P:intracellular signal transduction
GO:0016567--P:protein ubiquitination

KEGG

bta:614851

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001635	Ailuropoda melanoleuca	98.57	0.00e+00	841.00
IUUC-Apl-003903	Anas platyrhynchos	89.93	0.00e+00	781.00
IUUC-Aca-005214	Anolis carolinensis	78.40	0.00e+00	704.00
IUUC-Ame-011740	Astyanax mexicanus	75.53	0.00e+00	683.00
IUUC-Cja-019053	Callithrix jacchus	97.85	0.00e+00	859.00
IUUC-Cfa-020103	Canis familiaris	99.05	0.00e+00	845.00
IUUC-Cpo-022438	Cavia porcellus	95.49	0.00e+00	846.00
IUUC-Csa-024062	Chlorocebus sabaeus	98.10	0.00e+00	865.00
IUUC-Cho-024334	Choloepus hoffmanni	85.99	0.00e+00	711.00
IUUC-Cin-025590	Ciona intestinalis	39.39	2.00e-77	283.00
IUUC-Csv-026023	Ciona savignyi	40.33	5.00e-79	288.00
IUUC-Dre-028089	Danio rerio	75.12	0.00e+00	685.00
IUUC-Dno-029436	Dasypus novemcinctus	92.29	0.00e+00	676.00
IUUC-Dor-031107	Dipodomys ordii	90.02	0.00e+00	754.00
IUUC-Ete-032326	Echinops telfairi	95.31	0.00e+00	794.00
IUUC-Eca-033401	Equus caballus	98.34	0.00e+00	840.00
IUUC-Eeu-034520	Erinaceus europaeus	95.01	0.00e+00	843.00
IUUC-Fca-036386	Felis catus	99.05	0.00e+00	843.00
IUUC-Fal-036616	Ficedula albicollis	86.49	0.00e+00	752.00
IUUC-Gmo-039335	Gadus morhua	70.94	7.00e-179	619.00
IUUC-Gga-040856	Gallus gallus	88.60	0.00e+00	795.00
IUUC-Gac-042140	Gasterosteus aculeatus	74.41	0.00e+00	671.00
IUUC-Ggo-044619	Gorilla gorilla	98.10	0.00e+00	864.00
IUUC-Hsa-046300	Homo sapiens	97.86	0.00e+00	863.00
IUUC-Itr-048830	Ictidomys tridecemlineatus	96.44	0.00e+00	853.00
IUUC-Lch-049550	Latimeria chalumnae	80.64	1.00e-171	595.00
IUUC-Loc-051769	Lepisosteus oculatus	77.91	0.00e+00	694.00
IUUC-Laf-054576	Loxodonta africana	96.91	0.00e+00	833.00
IUUC-Mcc-054666	Macaca mulatta	98.09	1.00e-154	538.00
IUUC-Meu-055989	Macropus eugenii	89.14	0.00e+00	649.00
IUUC-Mga-059722	Meleagris gallopavo	87.95	0.00e+00	786.00
IUUC-Mmr-060970	Microcebus murinus	97.39	0.00e+00	835.00
IUUC-Mdo-062249	Monodelphis domestica	80.76	0.00e+00	657.00
IUUC-Mmu-063742	Mus musculus	92.86	0.00e+00	822.00
IUUC-Mpu-066518	Mustela putorius furo	98.34	0.00e+00	867.00
IUUC-Mlu-068063	Myotis lucifugus	95.96	0.00e+00	824.00
IUUC-Nle-069561	Nomascus leucogenys	97.62	0.00e+00	862.00
IUUC-Opr-071158	Ochotona princeps	92.38	0.00e+00	814.00
IUUC-Ont-072542	Oreochromis niloticus	73.24	0.00e+00	662.00
IUUC-Oan-073217	Ornithorhynchus anatinus	92.40	0.00e+00	816.00
IUUC-Ocu-074251	Oryctolagus cuniculus	96.33	0.00e+00	810.00
IUUC-Ola-086549	Oryzias latipes	72.07	0.00e+00	662.00
IUUC-Oga-088382	Otolemur garnettii	97.62	0.00e+00	839.00
IUUC-Oar-090263	Ovis aries	97.86	0.00e+00	852.00
IUUC-Ptr-090922	Pan troglodytes	97.62	0.00e+00	863.00
IUUC-Pan-092518	Papio anubis	98.10	0.00e+00	865.00
IUUC-Psi-093512	Pelodiscus sinensis	89.79	0.00e+00	801.00
IUUC-Pma-094324	Petromyzon marinus	58.80	2.00e-137	482.00
IUUC-Pfo-096264	Poecilia formosa	73.24	0.00e+00	667.00
IUUC-Pab-098018	Pongo abelii	96.20	0.00e+00	845.00
IUUC-Pca-101034	Procavia capensis	94.35	0.00e+00	772.00
IUUC-Pva-102862	Pteropus vampyrus	93.11	0.00e+00	769.00
IUUC-Rno-106116	Rattus norvegicus	93.82	0.00e+00	829.00
IUUC-Sha-106952	Sarcophilus harrisii	90.95	0.00e+00	762.00
IUUC-Sar-113211	Sorex araneus	85.22	1.00e-150	525.00
IUUC-Ssc-116440	Sus scrofa	99.05	0.00e+00	844.00
IUUC-Tgu-116675	Taeniopygia guttata	86.98	0.00e+00	754.00
IUUC-Tru-118295	Takifugu rubripes	72.77	0.00e+00	645.00
IUUC-Tsy-118916	Tarsius syrichta	85.04	0.00e+00	709.00
IUUC-Tni-120302	Tetraodon nigroviridis	72.07	0.00e+00	639.00
IUUC-Tbe-127416	Tupaia belangeri	84.03	0.00e+00	680.00
IUUC-Ttr-128185	Tursiops truncatus	99.29	0.00e+00	845.00
IUUC-Xtr-132465	Xenopus tropicalis	83.14	0.00e+00	748.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence