iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ont-072542

Ensembl Protein ID

ENSONIP00000018656.1

UniProt Accession

I3KC11; I3KC11_ORENI

Genbank Protein ID

ENSONIP00000018656

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AERX01050280

Gene Name

wsb1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSONIG00000014818.1	ENSONIT00000018673.1	ENSONIP00000018656.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.30e-32	110.9	174	208
UBD/Beta-Prp	1.90e-47	162.3	139	385

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd..tllvsGsdDgtikvWDlrtg 33
           Htd v++l f +d   +lvs+s+D+t++vWDl+++
   Q: 174  HTDVVRDLTFaPDgsLMLVSASRDKTLRVWDLKDD 208
           ***********7767889*************9887 PP

UBD/Beta-Prp

   S: 16   vkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgk.ilvtgseDrtikvwdls.tgkcvhtlkghedsvlslsf 102
            kf +d+ llatg  +g+ik+wdv tgkll  l +h++ v++++f pdg+ +lv++s+D+t++vwdl+ +g +v +l+gh++ v++ +f
   Q: 139  FKFGQDQLLLATGLNNGRIKIWDVYTGKLLLNLMDHTDVVRDLTFAPDGSlMLVSASRDKTLRVWDLKdDGNMVKVLRGHQNWVYCSAF 227
           68899999******************************************99***************989******************* PP
   S: 103  spsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtl............tggh 179
           sp+++ l s ++ + + +w++++ + ++  l+gh++ v + +++pdg ll+++s+D+ v +Wd   +++l +l             g++
   Q: 228  SPDSSILCSVGAGKSVFLWNMDKFTPIR-KLEGHHHDVVSCEFSPDGALLATASYDTRVIVWDHDKATILLELghlfpppspifaGGAN 315
           ****************************.9******************************************************98889 PP
   S: 180  tdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsiriWdl 251
           ++ v+s+sf ++g++++s+ +d+ v++w++++       ++  +n ++ +fs ++  l+ g+ Dgs+ +W +
   Q: 316  DRWVRSVSFCPDGRHIASVTDDRLVRFWSIEERA--PLAIASVSNGLCCAFSAQGSVLAAGTRDGSVHFWEC 385
           ******************************8885..66789999**************************76 PP

Organism

Oreochromis niloticus

Protein Sequence
(Fasta)

MASFPDSVNE NDIGKAKFIG ELLVPVAPFD QKSGREAWTV AFAPNGSYFA WSQGHRIVRL 60
IPWTKCLDSF SVGHGEEGTN ALSPRHLSRQ SSDGGQVVPA AGQPPEHTID CGDIVWGLAF 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCAAGCT TCCCAGACTC TGTGAACGAA AATGATATAG GTAAGTAAAA ATTTTACATG 60
TATTGTTTTT GTGAATGCAG GTGAGAACGC TGAACGATGT CCTGGCATTT CAATCGTAGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR027295--Quinoprotein_ADH-like_fam
IPR001496--SOCS_box
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS50225--SOCS
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF07525--SOCS_box
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00253--SOCS
SM00969--SOCS_box
SM00320--WD40

Gene Ontology

GO:0005622--C:intracellular
GO:0035556--P:intracellular signal transduction
GO:0016567--P:protein ubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001635	Ailuropoda melanoleuca	72.77	0.00e+00	645.00
IUUC-Apl-003903	Anas platyrhynchos	72.88	0.00e+00	638.00
IUUC-Aca-005214	Anolis carolinensis	63.34	1.00e-162	565.00
IUUC-Ame-011740	Astyanax mexicanus	82.67	0.00e+00	738.00
IUUC-Bta-013475	Bos taurus	73.24	0.00e+00	650.00
IUUC-Cja-019053	Callithrix jacchus	73.58	0.00e+00	657.00
IUUC-Cfa-020103	Canis familiaris	73.24	0.00e+00	649.00
IUUC-Cpo-022438	Cavia porcellus	72.54	0.00e+00	652.00
IUUC-Csa-024062	Chlorocebus sabaeus	73.24	0.00e+00	661.00
IUUC-Cho-024334	Choloepus hoffmanni	65.96	4.00e-161	560.00
IUUC-Cin-025590	Ciona intestinalis	40.05	1.00e-74	273.00
IUUC-Csv-026023	Ciona savignyi	39.38	4.00e-73	268.00
IUUC-Dre-028089	Danio rerio	82.90	0.00e+00	729.00
IUUC-Dno-029436	Dasypus novemcinctus	74.85	4.00e-155	541.00
IUUC-Dor-031107	Dipodomys ordii	68.31	1.00e-169	589.00
IUUC-Ete-032326	Echinops telfairi	73.41	0.00e+00	628.00
IUUC-Eca-033401	Equus caballus	73.24	0.00e+00	649.00
IUUC-Eeu-034520	Erinaceus europaeus	72.30	0.00e+00	653.00
IUUC-Fca-036386	Felis catus	72.54	0.00e+00	645.00
IUUC-Fal-036616	Ficedula albicollis	70.46	4.00e-178	617.00
IUUC-Gmo-039335	Gadus morhua	80.63	0.00e+00	683.00
IUUC-Gga-040856	Gallus gallus	73.24	0.00e+00	654.00
IUUC-Gac-042140	Gasterosteus aculeatus	88.76	0.00e+00	791.00
IUUC-Ggo-044619	Gorilla gorilla	73.71	0.00e+00	664.00
IUUC-Hsa-046300	Homo sapiens	73.24	0.00e+00	660.00
IUUC-Itr-048830	Ictidomys tridecemlineatus	73.94	0.00e+00	663.00
IUUC-Lch-049550	Latimeria chalumnae	73.58	4.00e-155	540.00
IUUC-Loc-051769	Lepisosteus oculatus	80.47	0.00e+00	699.00
IUUC-Laf-054576	Loxodonta africana	74.41	0.00e+00	655.00
IUUC-Mcc-054666	Macaca mulatta	75.19	1.00e-120	425.00
IUUC-Meu-055989	Macropus eugenii	73.07	4.00e-153	533.00
IUUC-Mga-059722	Meleagris gallopavo	71.84	0.00e+00	640.00
IUUC-Mmr-060970	Microcebus murinus	73.24	0.00e+00	647.00
IUUC-Mdo-062249	Monodelphis domestica	62.91	6.00e-151	526.00
IUUC-Mmu-063742	Mus musculus	71.53	0.00e+00	645.00
IUUC-Mpu-066518	Mustela putorius furo	73.00	0.00e+00	659.00
IUUC-Mlu-068063	Myotis lucifugus	72.30	0.00e+00	635.00
IUUC-Nle-069561	Nomascus leucogenys	73.47	0.00e+00	662.00
IUUC-Opr-071158	Ochotona princeps	70.35	1.00e-180	625.00
IUUC-Oan-073217	Ornithorhynchus anatinus	73.94	0.00e+00	662.00
IUUC-Ocu-074251	Oryctolagus cuniculus	73.06	0.00e+00	632.00
IUUC-Ola-086549	Oryzias latipes	85.25	0.00e+00	764.00
IUUC-Oga-088382	Otolemur garnettii	73.47	0.00e+00	649.00
IUUC-Oar-090263	Ovis aries	72.07	0.00e+00	644.00
IUUC-Ptr-090922	Pan troglodytes	73.47	0.00e+00	662.00
IUUC-Pan-092518	Papio anubis	73.24	0.00e+00	661.00
IUUC-Psi-093512	Pelodiscus sinensis	73.71	0.00e+00	657.00
IUUC-Pma-094324	Petromyzon marinus	57.64	6.00e-136	477.00
IUUC-Pfo-096264	Poecilia formosa	89.46	0.00e+00	799.00
IUUC-Pab-098018	Pongo abelii	72.07	0.00e+00	649.00
IUUC-Pca-101034	Procavia capensis	73.30	3.00e-176	610.00
IUUC-Pva-102862	Pteropus vampyrus	70.66	1.00e-171	595.00
IUUC-Rno-106116	Rattus norvegicus	71.83	0.00e+00	648.00
IUUC-Sha-106952	Sarcophilus harrisii	71.84	4.00e-177	613.00
IUUC-Sar-113211	Sorex araneus	67.80	1.00e-120	426.00
IUUC-Ssc-116440	Sus scrofa	73.00	0.00e+00	647.00
IUUC-Tgu-116675	Taeniopygia guttata	71.43	1.00e-178	619.00
IUUC-Tru-118295	Takifugu rubripes	85.25	0.00e+00	756.00
IUUC-Tsy-118916	Tarsius syrichta	62.68	1.00e-153	536.00
IUUC-Tni-120302	Tetraodon nigroviridis	85.25	0.00e+00	753.00
IUUC-Tbe-127416	Tupaia belangeri	61.89	2.00e-145	508.00
IUUC-Ttr-128185	Tursiops truncatus	73.47	0.00e+00	649.00
IUUC-Xtr-132465	Xenopus tropicalis	72.37	0.00e+00	657.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence