iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Pfo-096264

Ensembl Protein ID

ENSPFOP00000006889.1

UniProt Accession

A0A087XM86; A0A087XM86_POEFO

Genbank Protein ID

ENSPFOP00000006889

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AYCK01015355

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPFOG00000006911.2	ENSPFOT00000006901.2	ENSPFOP00000006889.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	3.60e-30	103.3	174	208
E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box	7.60e-13	48.7	381	425
UBD/Beta-Prp	2.40e-47	162.1	139	384

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd..tllvsGsdDgtikvWDlrtg 33
           Htd v++l f +d   +lvs+s+D+t++vWDl+++
   Q: 174  HTDVVRDLTFaPDgsLMLVSASRDKTLRVWDLKDD 208
           ***********7767889*************9887 PP

E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box

   S: 3    klwllrseprSLqhLCRlaIrrclgsqrlkaidkLPLPksLkdYLlye 50
            +w+++++  SLqh CR+a rr+l++q++   ++L +P  L+dYL y+
   Q: 381  HFWEAPRSIASLQHMCRMALRRLLTTQQV---EALAIPTPLQDYLTYK 425
           69************************999...**************98 PP

UBD/Beta-Prp

   S: 16   vkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgk.ilvtgseDrtikvwdls.tgkcvhtlkghedsvlslsf 102
            kf +d+ llatg  +g+ik+wdv +gkll  l +h++ v++++f pdg+ +lv++s+D+t++vwdl+ +g +v +l+gh++ v + sf
   Q: 139  FKFGQDQLLLATGLNNGRIKIWDVYSGKLLLNLMDHTDVVRDLTFAPDGSlMLVSASRDKTLRVWDLKdDGNMVKVLRGHQNWVHCSSF 227
           67899999*****************************************9999**************9899****************** PP
   S: 103  spsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtl............tggh 179
           sp+++ l s ++ + + +w++++++ ++  l+gh+  v + +++pdg ll+++s+D+ v +Wd   g++l +l             g++
   Q: 228  SPDSSILCSVGAGKAVLIWNMDKYTLIR-KLEGHHNDVVSCEFSPDGALLATASYDTRVIVWDHHKGTILLELghlfpppspifaGGAN 315
           ***************************9.9999999999999******************************************98889 PP
   S: 180  tdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsiriWd 250
           ++ v+s+sf ++g++++s+ +d+ v++w+++++    + ++  +n ++ +fs ++  l+ g+ Dgs+ +W 
   Q: 316  DRWVRSVSFCPDGRHIASITDDRFVRFWSIEEK--APQAIASLSNGLCCAFSAEGSVLAAGTRDGSVHFWE 384
           99****************************888..68999999***************************3 PP

Organism

Poecilia formosa

Protein Sequence
(Fasta)

MASFPDCVNE NDLDKAKFVG ELLVPVAPFD QKSGREAWTV AFAPNGSYFA WSQGHRIVRL 60
IPWNKCLKSF SLSAGEEGTN PTSPRHLSRQ NSDGGVTIPL ADEPREHTID CGDIVWGLAF 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CAACCGCGGT GACGTAAAAA TCCTCCCTCC CTGGACATTT ATAGCCAGTC CTTCGAATAA 60
ATAAAGTGCC ATTTCCAATT TAGGCATTCT AGTATGAAAC AGCAGCTTCG TTCTTTAATC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR011045--N2O_reductase_N
IPR001496--SOCS_box
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS50225--SOCS
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF07525--SOCS_box
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00253--SOCS
SM00969--SOCS_box
SM00320--WD40

Gene Ontology

GO:0005622--C:intracellular
GO:0035556--P:intracellular signal transduction
GO:0016567--P:protein ubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001635	Ailuropoda melanoleuca	72.30	0.00e+00	644.00
IUUC-Apl-003903	Anas platyrhynchos	73.30	0.00e+00	642.00
IUUC-Aca-005214	Anolis carolinensis	63.34	6.00e-164	570.00
IUUC-Ame-011740	Astyanax mexicanus	83.06	0.00e+00	746.00
IUUC-Bta-013475	Bos taurus	72.77	0.00e+00	648.00
IUUC-Cja-019053	Callithrix jacchus	73.35	0.00e+00	661.00
IUUC-Cfa-020103	Canis familiaris	72.77	0.00e+00	648.00
IUUC-Cpo-022438	Cavia porcellus	72.07	0.00e+00	655.00
IUUC-Csa-024062	Chlorocebus sabaeus	73.00	0.00e+00	665.00
IUUC-Cho-024334	Choloepus hoffmanni	65.73	4.00e-161	560.00
IUUC-Cin-025590	Ciona intestinalis	39.90	3.00e-77	282.00
IUUC-Csv-026023	Ciona savignyi	40.76	4.00e-77	281.00
IUUC-Dre-028089	Danio rerio	82.67	0.00e+00	744.00
IUUC-Dno-029436	Dasypus novemcinctus	75.69	2.00e-156	545.00
IUUC-Dor-031107	Dipodomys ordii	67.84	3.00e-169	587.00
IUUC-Ete-032326	Echinops telfairi	73.90	0.00e+00	631.00
IUUC-Eca-033401	Equus caballus	72.77	0.00e+00	647.00
IUUC-Eeu-034520	Erinaceus europaeus	71.36	0.00e+00	650.00
IUUC-Fca-036386	Felis catus	72.07	0.00e+00	644.00
IUUC-Fal-036616	Ficedula albicollis	70.87	1.00e-179	622.00
IUUC-Gmo-039335	Gadus morhua	81.11	0.00e+00	691.00
IUUC-Gga-040856	Gallus gallus	73.00	0.00e+00	656.00
IUUC-Gac-042140	Gasterosteus aculeatus	87.59	0.00e+00	787.00
IUUC-Ggo-044619	Gorilla gorilla	73.47	0.00e+00	668.00
IUUC-Hsa-046300	Homo sapiens	73.00	0.00e+00	664.00
IUUC-Itr-048830	Ictidomys tridecemlineatus	73.47	0.00e+00	667.00
IUUC-Lch-049550	Latimeria chalumnae	74.72	2.00e-158	551.00
IUUC-Loc-051769	Lepisosteus oculatus	80.00	0.00e+00	707.00
IUUC-Laf-054576	Loxodonta africana	73.94	0.00e+00	653.00
IUUC-Mcc-054666	Macaca mulatta	74.43	8.00e-121	426.00
IUUC-Meu-055989	Macropus eugenii	73.56	7.00e-155	540.00
IUUC-Mga-059722	Meleagris gallopavo	73.30	0.00e+00	645.00
IUUC-Mmr-060970	Microcebus murinus	72.54	0.00e+00	644.00
IUUC-Mdo-062249	Monodelphis domestica	62.91	1.00e-149	522.00
IUUC-Mmu-063742	Mus musculus	70.59	0.00e+00	642.00
IUUC-Mpu-066518	Mustela putorius furo	72.77	0.00e+00	662.00
IUUC-Mlu-068063	Myotis lucifugus	71.60	0.00e+00	632.00
IUUC-Nle-069561	Nomascus leucogenys	73.47	0.00e+00	668.00
IUUC-Opr-071158	Ochotona princeps	70.12	0.00e+00	632.00
IUUC-Ont-072542	Oreochromis niloticus	89.46	0.00e+00	799.00
IUUC-Oan-073217	Ornithorhynchus anatinus	73.65	0.00e+00	665.00
IUUC-Ocu-074251	Oryctolagus cuniculus	72.22	0.00e+00	634.00
IUUC-Ola-086549	Oryzias latipes	86.42	0.00e+00	777.00
IUUC-Oga-088382	Otolemur garnettii	72.54	0.00e+00	647.00
IUUC-Oar-090263	Ovis aries	71.83	0.00e+00	648.00
IUUC-Ptr-090922	Pan troglodytes	73.24	0.00e+00	666.00
IUUC-Pan-092518	Papio anubis	73.00	0.00e+00	665.00
IUUC-Psi-093512	Pelodiscus sinensis	73.00	0.00e+00	656.00
IUUC-Pma-094324	Petromyzon marinus	57.41	6.00e-138	484.00
IUUC-Pab-098018	Pongo abelii	71.83	0.00e+00	652.00
IUUC-Pca-101034	Procavia capensis	72.82	3.00e-175	607.00
IUUC-Pva-102862	Pteropus vampyrus	69.48	3.00e-169	588.00
IUUC-Rno-106116	Rattus norvegicus	71.60	0.00e+00	652.00
IUUC-Sha-106952	Sarcophilus harrisii	71.26	1.00e-179	622.00
IUUC-Sar-113211	Sorex araneus	67.80	6.00e-121	427.00
IUUC-Ssc-116440	Sus scrofa	72.54	0.00e+00	646.00
IUUC-Tgu-116675	Taeniopygia guttata	71.36	2.00e-179	621.00
IUUC-Tru-118295	Takifugu rubripes	84.78	0.00e+00	762.00
IUUC-Tsy-118916	Tarsius syrichta	62.44	8.00e-154	536.00
IUUC-Tni-120302	Tetraodon nigroviridis	84.07	0.00e+00	754.00
IUUC-Tbe-127416	Tupaia belangeri	62.86	1.00e-149	522.00
IUUC-Ttr-128185	Tursiops truncatus	73.00	0.00e+00	648.00
IUUC-Xtr-132465	Xenopus tropicalis	72.13	0.00e+00	664.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence