iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Fal-037427

Ensembl Protein ID

ENSFALP00000010148.1

UniProt Accession

U3K544; U3K544_FICAL

Genbank Protein ID

ENSFALP00000010148

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGTO01001464

Gene Name

RFFL

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSFALG00000009730.1	ENSFALT00000010188.1	ENSFALP00000010148.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	65.40	3.00e-132	469.00	IUUC-Hsa-045798

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Ficedula albicollis

Protein Sequence
(Fasta)

MHCSALRVQR NHIEEFLGGG DNPVTAELMS GPGLTCMQRF LTPCCRCGLR RLWNCAFALD 60
CFRIFGTMWA SCCNWFCVDG SPEEMQPPAA APAQAYSNPG FSSFPSPTAS EQSCKACGRH 120

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Nucleotide Sequence
(Fasta)

TAGGATGGCT TTCAGTGAGG CTCAGTCTCT CATTGTCAGG TACCATGTGA TTTGGCTCCC 60
CAAATGAGAG CTGAATGCAT TGCTCTGCAC TGAGAGTACA AAGGAATCAT ATAGAGGAGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001370--BIR_rpt
IPR003034--SAP_dom
IPR011011--Znf_FYVE_PHD
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50089--ZF_RING_2

SMART

SM00184--RING

Gene Ontology

GO:0010008--C:endosome membrane
GO:0005886--C:plasma membrane
GO:0002947--C:tumor necrosis factor receptor superfamily complex
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:2001271--P:negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis
GO:1902042--P:negative regulation of extrinsic apoptotic signaling pathway via death domain receptors
GO:1901797--P:negative regulation of signal transduction by p53 class mediator
GO:0010804--P:negative regulation of tumor necrosis factor-mediated signaling pathway
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0070936--P:protein K48-linked ubiquitination
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001630	Ailuropoda melanoleuca	63.76	1.00e-122	432.00
IUUC-Apl-004124	Anas platyrhynchos	79.40	7.00e-144	503.00
IUUC-Aly-005548	Arabidopsis lyrata	49.02	5.00e-09	56.60
IUUC-Ame-011616	Astyanax mexicanus	55.77	8.00e-97	346.00
IUUC-Bta-012374	Bos taurus	63.99	3.00e-123	434.00
IUUC-Cja-019780	Callithrix jacchus	64.67	8.00e-127	446.00
IUUC-Cfa-021252	Canis familiaris	66.21	7.00e-125	439.00
IUUC-Cpo-022047	Cavia porcellus	65.22	6.00e-129	453.00
IUUC-Csa-023161	Chlorocebus sabaeus	65.40	5.00e-132	463.00
IUUC-Cho-024316	Choloepus hoffmanni	64.92	4.00e-105	374.00
IUUC-Dre-028596	Danio rerio	53.46	1.00e-102	365.00
IUUC-Dno-029333	Dasypus novemcinctus	65.67	2.00e-129	455.00
IUUC-Ete-033163	Echinops telfairi	65.10	3.00e-123	434.00
IUUC-Eca-033994	Equus caballus	65.67	2.00e-129	454.00
IUUC-Eeu-035162	Erinaceus europaeus	62.21	7.00e-84	303.00
IUUC-Fca-036418	Felis catus	67.03	6.00e-135	473.00
IUUC-Gga-041053	Gallus gallus	82.27	2.00e-162	565.00
IUUC-Ggo-045436	Gorilla gorilla	65.40	1.00e-133	469.00
IUUC-Hsa-045798	Homo sapiens	65.40	1.00e-133	469.00
IUUC-Itr-048077	Ictidomys tridecemlineatus	64.93	1.00e-125	442.00
IUUC-Lch-050639	Latimeria chalumnae	57.30	7.00e-113	399.00
IUUC-Laf-053355	Loxodonta africana	63.41	4.00e-122	430.00
IUUC-Mcc-055222	Macaca mulatta	64.85	3.00e-126	444.00
IUUC-Meu-056692	Macropus eugenii	64.84	8.00e-124	436.00
IUUC-Mga-059298	Meleagris gallopavo	82.04	1.00e-161	562.00
IUUC-Mmr-061792	Microcebus murinus	67.49	4.00e-127	447.00
IUUC-Mdo-062986	Monodelphis domestica	67.40	7.00e-132	463.00
IUUC-Mmu-063356	Mus musculus	64.50	8.00e-126	442.00
IUUC-Mpu-066273	Mustela putorius furo	65.67	2.00e-133	468.00
IUUC-Mlu-066953	Myotis lucifugus	67.58	4.00e-129	453.00
IUUC-Nle-070075	Nomascus leucogenys	65.67	7.00e-134	469.00
IUUC-Opr-070838	Ochotona princeps	65.04	3.00e-129	454.00
IUUC-Ont-071967	Oreochromis niloticus	67.63	3.00e-49	188.00
IUUC-Ocu-074807	Oryctolagus cuniculus	65.93	1.00e-130	459.00
IUUC-Ola-086903	Oryzias latipes	67.63	2.00e-50	192.00
IUUC-Oga-088536	Otolemur garnettii	67.03	6.00e-126	443.00
IUUC-Oar-089838	Ovis aries	63.99	4.00e-122	430.00
IUUC-Ptr-090962	Pan troglodytes	65.40	2.00e-133	468.00
IUUC-Pan-092853	Papio anubis	64.85	2.00e-131	461.00
IUUC-Psi-093164	Pelodiscus sinensis	72.45	2.00e-140	491.00
IUUC-Pma-094104	Petromyzon marinus	42.86	2.00e-54	206.00
IUUC-Pno-094968	Phaeosphaeria nodorum	36.73	2.00e-08	55.50
IUUC-Pab-098304	Pongo abelii	65.40	2.00e-132	464.00
IUUC-Pca-100316	Procavia capensis	64.31	6.00e-122	430.00
IUUC-Ppe-101490	Prunus persica	47.06	7.00e-09	55.10
IUUC-Pva-102612	Pteropus vampyrus	54.50	5.00e-96	344.00
IUUC-Rno-105449	Rattus norvegicus	65.30	2.00e-126	444.00
IUUC-Sha-107578	Sarcophilus harrisii	65.79	5.00e-123	433.00
IUUC-Sar-113638	Sorex araneus	64.01	2.00e-121	428.00
IUUC-Ssc-116401	Sus scrofa	67.03	3.00e-134	471.00
IUUC-Tru-118765	Takifugu rubripes	48.07	1.00e-76	279.00
IUUC-Tsy-118850	Tarsius syrichta	63.28	2.00e-101	362.00
IUUC-Tbe-128086	Tupaia belangeri	61.54	4.00e-123	434.00
IUUC-Vpa-130816	Vicugna pacos	74.42	3.00e-33	135.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence