iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Pan-092830

Ensembl Protein ID

ENSPANP00000020334.1

UniProt Accession

A0A096P4Q9; A0A096P4Q9_PAPAN

Genbank Protein ID

ENSPANP00000020334

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AHZZ01070166

Gene Name

TRIM25

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPANG00000022321.1	ENSPANT00000002069.1	ENSPANP00000020334.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	9.40e-09	35.7	13	54

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadCl.qkwpglknssskefrCPlCr 46
           C+iCle+fk+ p+++pCgH f+ +Cl + w     ++    +CP Cr
   Q: 13   CSICLEPFKE-PVTTPCGHNFCGSCLnETW----AVQGAPYLCPQCR 54
           ********99.****************9**....8999999*****8 PP

Organism

Papio anubis

Protein Sequence
(Fasta)

MAQLCPLAEE LSCSICLEPF KEPVTTPCGH NFCGSCLNET WAVQGAPYLC PQCRAVYQAR 60
PQLHKNTVLC NVVEQFLQAE LAREPPADGW TPPARASAPS PGAQVACDHC LKEAAVKTCL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CGCCCCACGT GACTTCCTGA CGGCTGCAGG GACTGCCCTT CCCGGGCTAG GTTTCGTTTC 60
CTCGGCAGCC TCGGAGCGCG GTTGCAGTAG TCGCGTCCCG ACCCCTGGGA GCAGCATGGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001870--B30.2/SPRY
IPR003879--Butyrophylin
IPR013320--ConA-like_dom
IPR006574--PRY
IPR003877--SPRY_dom
IPR027370--Znf-RING_LisH
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50188--B302_SPRY
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF13765--PRY
PF00622--SPRY
PF13445--zf-RING_UBOX

PRINTS

PR01407--BUTYPHLNCDUF

SMART

SM00589--PRY
SM00184--RING
SM00449--SPRY

Gene Ontology

GO:0005829--C:cytosol
GO:0016604--C:nuclear body
GO:0003723--F:RNA binding
GO:1904264--F:ubiquitin protein ligase activity involved in ERAD pathway
GO:0008270--F:zinc ion binding
GO:0045087--P:innate immune response
GO:0046597--P:negative regulation of viral entry into host cell
GO:1902187--P:negative regulation of viral release from host cell
GO:0043123--P:positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0051092--P:positive regulation of NF-kappaB transcription factor activity
GO:0006513--P:protein monoubiquitination
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0043627--P:response to estrogen

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002424	Ailuropoda melanoleuca	78.48	0.00e+00	989.00
IUUC-Apl-004101	Anas platyrhynchos	50.32	1.00e-167	583.00
IUUC-Aca-005025	Anolis carolinensis	49.69	3.00e-175	608.00
IUUC-Ame-010928	Astyanax mexicanus	30.09	1.00e-57	217.00
IUUC-Bta-012735	Bos taurus	74.02	0.00e+00	951.00
IUUC-Cja-019996	Callithrix jacchus	83.51	0.00e+00	736.00
IUUC-Cfa-020466	Canis familiaris	75.20	0.00e+00	971.00
IUUC-Cpo-021737	Cavia porcellus	70.62	0.00e+00	887.00
IUUC-Csa-023217	Chlorocebus sabaeus	98.73	0.00e+00	1213.00
IUUC-Cho-024346	Choloepus hoffmanni	51.00	6.00e-72	264.00
IUUC-Dre-028781	Danio rerio	29.68	2.00e-63	237.00
IUUC-Dno-030082	Dasypus novemcinctus	74.33	0.00e+00	955.00
IUUC-Dor-030335	Dipodomys ordii	54.22	1.00e-132	466.00
IUUC-Ete-032923	Echinops telfairi	69.56	0.00e+00	794.00
IUUC-Eca-033411	Equus caballus	74.92	0.00e+00	955.00
IUUC-Eeu-034656	Erinaceus europaeus	72.85	4.00e-162	564.00
IUUC-Fca-035371	Felis catus	77.20	0.00e+00	979.00
IUUC-Fal-037008	Ficedula albicollis	45.60	5.00e-158	551.00
IUUC-Gmo-038668	Gadus morhua	33.60	7.00e-104	370.00
IUUC-Gga-040608	Gallus gallus	49.52	3.00e-163	568.00
IUUC-Gac-041409	Gasterosteus aculeatus	36.41	2.00e-116	412.00
IUUC-Ggo-044518	Gorilla gorilla	93.66	0.00e+00	1127.00
IUUC-Hsa-045828	Homo sapiens	94.44	0.00e+00	1166.00
IUUC-Itr-049070	Ictidomys tridecemlineatus	55.35	0.00e+00	657.00
IUUC-Lch-050478	Latimeria chalumnae	36.71	3.00e-111	395.00
IUUC-Loc-052864	Lepisosteus oculatus	37.05	1.00e-113	403.00
IUUC-Laf-054325	Loxodonta africana	77.72	6.00e-172	596.00
IUUC-Mcc-054920	Macaca mulatta	99.52	0.00e+00	1224.00
IUUC-Meu-056367	Macropus eugenii	72.83	7.00e-75	275.00
IUUC-Mga-059975	Meleagris gallopavo	49.37	4.00e-164	571.00
IUUC-Mmr-060748	Microcebus murinus	81.80	0.00e+00	1005.00
IUUC-Mdo-062904	Monodelphis domestica	57.85	0.00e+00	703.00
IUUC-Mmu-063891	Mus musculus	72.10	0.00e+00	945.00
IUUC-Mpu-066473	Mustela putorius furo	77.48	0.00e+00	997.00
IUUC-Mlu-068185	Myotis lucifugus	75.00	0.00e+00	958.00
IUUC-Nle-070177	Nomascus leucogenys	94.60	0.00e+00	1169.00
IUUC-Opr-070558	Ochotona princeps	62.61	7.00e-155	540.00
IUUC-Ont-071368	Oreochromis niloticus	35.38	1.00e-106	380.00
IUUC-Ocu-074461	Oryctolagus cuniculus	57.75	0.00e+00	665.00
IUUC-Opu-083547	Oryza punctata	45.95	4.00e-11	62.40
IUUC-Ola-087394	Oryzias latipes	29.25	1.00e-60	227.00
IUUC-Oga-088937	Otolemur garnettii	75.28	0.00e+00	956.00
IUUC-Oar-089781	Ovis aries	75.11	0.00e+00	652.00
IUUC-Ptr-090771	Pan troglodytes	94.44	0.00e+00	1147.00
IUUC-Psi-093664	Pelodiscus sinensis	52.47	1.00e-179	623.00
IUUC-Pma-094147	Petromyzon marinus	28.13	3.00e-63	236.00
IUUC-Pab-097588	Pongo abelii	94.44	0.00e+00	1157.00
IUUC-Pca-100890	Procavia capensis	73.73	0.00e+00	889.00
IUUC-Pva-102314	Pteropus vampyrus	81.52	0.00e+00	974.00
IUUC-Pgr-103377	Puccinia graminis	39.29	2.00e-06	47.40
IUUC-Rno-105234	Rattus norvegicus	70.42	0.00e+00	909.00
IUUC-Sce-106362	Saccharomyces cerevisiae	44.93	5.00e-09	55.50
IUUC-Sha-106807	Sarcophilus harrisii	53.26	0.00e+00	654.00
IUUC-Sar-113283	Sorex araneus	59.03	1.00e-136	479.00
IUUC-Ssc-115878	Sus scrofa	80.43	2.00e-107	381.00
IUUC-Tgu-117026	Taeniopygia guttata	46.35	3.00e-130	458.00
IUUC-Tru-118624	Takifugu rubripes	26.76	5.00e-59	222.00
IUUC-Tni-120550	Tetraodon nigroviridis	26.66	1.00e-64	240.00
IUUC-Tbe-127580	Tupaia belangeri	73.30	3.00e-158	551.00
IUUC-Ttr-128648	Tursiops truncatus	73.01	0.00e+00	657.00
IUUC-Vpa-130254	Vicugna pacos	90.29	3.00e-98	351.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence