iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Cpo-021568

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAKN02033080

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCPOG00000005504.3	ENSCPOT00000005563.2	ENSCPOP00000004957.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	3.40e-107	358.5	676	1510

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle.kkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsg 86
           tGl+NlgNtC+mNS +Qc sn+++l++++ + ++  +ln++np ++kg+++k++ +l++elw++++k+v+p +l  +++k+a++f+g
   Q: 676  TGLSNLGNTCFMNSSIQCVSNTQPLTQYFISgRHLYELNRTNPIGMKGHMAKCYGDLVQELWSGTQKNVAPLKLRWTIAKYAPRFNG 762
           7******************************9******************************************************* PP
   S: 87   yeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsde.....aeekkkkknkslisdlFqgqlksqikclecdnvssreep 168
           ++qqD+qE+laflld+l+e+l++ ++kp+ e++++d   ++d+     a++++ ++n+s+++dlF+gql+sq+kc++c+++s+r++p
   Q: 763  FQQQDSQELLAFLLDGLHEDLNRVHEKPYVELKDSD--GRPDWevaaeAWDNHLRRNRSIVVDLFHGQLRSQVKCKTCGHISVRFDP 847
           ********************************9999..6666666777*************************************** PP
   S: 169  fldlslpvpgkeetkke...................................................................... 185
           f+ lslp+p+++ +++e                                                                      
   Q: 848  FNFLSLPLPMDSYMHLEitvikldgttpiryglrlnmdekytglkkqlsdlcglkseqillaevhgsniknfpqdnqkvrlsvsgfl 934
           *************9999********************************************************************** PP
   S: 186  ....................................................................................... 185
                                                                                                  
   Q: 935  cafeipipaspisasspiqtdfssspstngmfslttngdmprpifipngmpntvvpcgteknftngimnghmsslpdntftgyiiai 1021
           *************************************************************************************** PP
   S: 186  ....................................................................................... 185
                                                                                                  
   Q: 1022 hrkmmrtelyflssqknrpslfgmplivpctihtrkkdlydavwiqvsrlasplppqeasnhaqdcddsmgyqypftlrvvqkdgns 1108
           *************************************************************************************** PP
   S: 186  ...................................................................slqdcLesftkeeelegenk 205
                                                                              +l++cL++ft+eeel ++++
   Q: 1109 cascpwyrfcrgckidcgedkafignayiavdwdptalhlryqtsqervvdehdsveqsrraqaepiNLDSCLRAFTNEEELGENEM 1195
           *************************************************************************************** PP
   S: 206  yycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefple.Ldlspfcts........................ 267
           yyc+kck ++ a+kkl+l++lP++Li+hLkRf+f +   + +k +k v+fp+e +d s f++                         
   Q: 1196 YYCSKCKTHCLATKKLDLWRLPPILIIHLKRFQFVNG--RWIKSQKIVKFPREnFDPSAFLVPrdpalcqhkpltpqgedlseprvp 1280
           ********************************99775..5569******************99999999999999999999999999 PP
   S: 268  ....................................................................................... 267
                                                                                                  
   Q: 1281 agevkkadaqnstgdedvllskspsslsanltsspkgspsssrksgascpssknsspnssprtlgrskgrlrlpqigsknklssske 1367
           999999999999999999999999999998888888888888888888888777777777777777777777777777777766666 PP
   S: 268  ..................................................................peekqke.............. 274
                                                                                   +              
   Q: 1368 nldaskengaghgceladtlsrghllggsqpelstpqdnevslasglilyeheacgngyssgqlgnH-----Seedstddqredths 1449
           6666666666666666666666666666666666655555555555555555555555555555550.....055555555666666 PP
   S: 275  kkkYeLiavvvHsGslssGHYvayvknekgkWllfdDskVtevkeeevleetgstaYvlfYkrr 338
           k +Y+L+a+ +HsG l++GHYv+y+kn + kW++++Ds+++e++ +e+ +   ++aY+lfY+++
   Q: 1450 KPIYNLYAISCHSGILGGGHYVTYAKNPNCKWYCYNDSSCKELHPDEIDT---DSAYILFYEQQ 1510
           **************************************************...********985 PP

Organism

Cavia porcellus

Protein Sequence
(Fasta)

VIYCSFGGTS KGLHFNNLIV GLVLLTRGKD EEKTKLVYSL LNSQNLKFIY LMRLLSERMS 60
EIKISQLRDD IGKWNSQGEK VNYEKFRNWL LLNKDAFTFS RWLLSGGVYV TLTDDSDTPT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTAATTTACT GTTCTTTTGG TGGAACATCC AAAGGGCTGC ACTTCAATAA CTTAATAGTT 60
GGACTTGTGC TCCTTACAAG AGGCAAAGAT GAAGAAAAAA CAAAATGTAA GTACTTTTAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0106--Calcium
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR011992--EF-hand-dom_pair
IPR018247--EF_Hand_1_Ca_BS
IPR002048--EF_hand_dom
IPR006615--Pept_C19_DUSP
IPR001394--Peptidase_C19_UCH
IPR028135--Ub_USP-typ
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS51283--DUSP
PS00018--EF_HAND_1
PS50222--EF_HAND_2
PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF06337--DUSP
PF13202--EF-hand_5
PF14836--Ubiquitin_3
PF00443--UCH

SMART

SM00695--DUSP
SM00054--EFh

Gene Ontology

GO:0005829--C:cytosol
GO:0005794--C:Golgi apparatus
GO:0005509--F:calcium ion binding
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001611	Ailuropoda melanoleuca	92.58	0.00e+00	2500.00
IUUC-Apl-003272	Anas platyrhynchos	79.09	0.00e+00	2448.00
IUUC-Aca-005057	Anolis carolinensis	79.63	0.00e+00	2075.00
IUUC-Ame-010781	Astyanax mexicanus	71.09	0.00e+00	2154.00
IUUC-Bta-013502	Bos taurus	87.76	0.00e+00	2658.00
IUUC-Cja-018754	Callithrix jacchus	91.47	0.00e+00	2778.00
IUUC-Cfa-020526	Canis familiaris	91.67	0.00e+00	2779.00
IUUC-Csa-023143	Chlorocebus sabaeus	91.53	0.00e+00	2746.00
IUUC-Cho-024603	Choloepus hoffmanni	63.82	7.00e-141	495.00
IUUC-Cin-025583	Ciona intestinalis	49.41	0.00e+00	1154.00
IUUC-Csv-026344	Ciona savignyi	45.41	0.00e+00	1050.00
IUUC-Dre-028121	Danio rerio	72.13	0.00e+00	2114.00
IUUC-Dno-029911	Dasypus novemcinctus	89.49	0.00e+00	2737.00
IUUC-Dor-030608	Dipodomys ordii	57.28	0.00e+00	979.00
IUUC-Dme-032094	Drosophila melanogaster	45.02	4.00e-123	436.00
IUUC-Ete-032639	Echinops telfairi	92.13	0.00e+00	1555.00
IUUC-Eca-034253	Equus caballus	91.41	0.00e+00	2789.00
IUUC-Eeu-035084	Erinaceus europaeus	78.38	0.00e+00	1442.00
IUUC-Fca-035474	Felis catus	92.03	0.00e+00	2381.00
IUUC-Fal-036985	Ficedula albicollis	80.29	0.00e+00	2415.00
IUUC-Gmo-039568	Gadus morhua	75.91	0.00e+00	1884.00
IUUC-Gga-040509	Gallus gallus	78.65	0.00e+00	2450.00
IUUC-Gac-041757	Gasterosteus aculeatus	76.07	0.00e+00	1948.00
IUUC-Ggo-044956	Gorilla gorilla	81.84	0.00e+00	1570.00
IUUC-Hsa-046107	Homo sapiens	91.53	0.00e+00	2771.00
IUUC-Itr-048865	Ictidomys tridecemlineatus	93.67	0.00e+00	1166.00
IUUC-Lch-050681	Latimeria chalumnae	74.60	0.00e+00	2216.00
IUUC-Loc-052474	Lepisosteus oculatus	73.74	0.00e+00	2224.00
IUUC-Laf-054273	Loxodonta africana	90.12	0.00e+00	2731.00
IUUC-Mcc-054718	Macaca mulatta	91.47	0.00e+00	2771.00
IUUC-Meu-056558	Macropus eugenii	67.43	0.00e+00	1172.00
IUUC-Mga-059892	Meleagris gallopavo	80.41	0.00e+00	2490.00
IUUC-Mmr-060866	Microcebus murinus	90.76	0.00e+00	2799.00
IUUC-Mdo-062607	Monodelphis domestica	86.83	0.00e+00	2666.00
IUUC-Mmu-063797	Mus musculus	90.43	0.00e+00	2800.00
IUUC-Mpu-066121	Mustela putorius furo	91.60	0.00e+00	2791.00
IUUC-Mlu-067581	Myotis lucifugus	89.89	0.00e+00	2782.00
IUUC-Nle-069916	Nomascus leucogenys	89.08	0.00e+00	2672.00
IUUC-Opr-071073	Ochotona princeps	74.55	0.00e+00	962.00
IUUC-Ont-071310	Oreochromis niloticus	75.17	0.00e+00	1910.00
IUUC-Oan-073356	Ornithorhynchus anatinus	85.41	0.00e+00	2615.00
IUUC-Ocu-074216	Oryctolagus cuniculus	90.30	0.00e+00	2744.00
IUUC-Ola-087434	Oryzias latipes	75.35	0.00e+00	1887.00
IUUC-Oga-089034	Otolemur garnettii	91.21	0.00e+00	2793.00
IUUC-Oar-090369	Ovis aries	91.28	0.00e+00	2820.00
IUUC-Ptr-090605	Pan troglodytes	91.47	0.00e+00	2770.00
IUUC-Pan-092381	Papio anubis	91.54	0.00e+00	2776.00
IUUC-Psi-093819	Pelodiscus sinensis	82.82	0.00e+00	2548.00
IUUC-Pma-094480	Petromyzon marinus	59.87	0.00e+00	1296.00
IUUC-Pfo-096561	Poecilia formosa	75.73	0.00e+00	1886.00
IUUC-Pab-097643	Pongo abelii	91.27	0.00e+00	2759.00
IUUC-Pca-100944	Procavia capensis	76.46	0.00e+00	1010.00
IUUC-Pva-102732	Pteropus vampyrus	80.80	0.00e+00	2371.00
IUUC-Rno-105113	Rattus norvegicus	90.56	0.00e+00	2780.00
IUUC-Sha-107608	Sarcophilus harrisii	83.42	1.00e-165	575.00
IUUC-Sar-113201	Sorex araneus	82.79	0.00e+00	1670.00
IUUC-Ssc-115469	Sus scrofa	91.79	0.00e+00	630.00
IUUC-Tgu-117322	Taeniopygia guttata	81.41	0.00e+00	2476.00
IUUC-Tru-118705	Takifugu rubripes	59.69	0.00e+00	885.00
IUUC-Tsy-119433	Tarsius syrichta	79.24	0.00e+00	1825.00
IUUC-Tni-120631	Tetraodon nigroviridis	75.40	0.00e+00	1930.00
IUUC-Tbe-127553	Tupaia belangeri	84.57	0.00e+00	674.00
IUUC-Ttr-128260	Tursiops truncatus	89.99	0.00e+00	2763.00
IUUC-Vpa-130479	Vicugna pacos	86.50	0.00e+00	2588.00
IUUC-Xtr-132686	Xenopus tropicalis	79.70	0.00e+00	2378.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence