iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Psi-093819

Ensembl Protein ID

ENSPSIP00000012154.1

UniProt Accession

K7FVU4; K7FVU4_PELSI

Genbank Protein ID

ENSPSIP00000012154

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGCU01199497

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPSIG00000010750.1	ENSPSIT00000012212.1	ENSPSIP00000012154.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	5.40e-108	361.2	693	1529

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle.kkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsg 86
           tGl+NlgNtC+mNS +Qc sn+++l++++ + k+  +ln++np ++kg+++k++ +l++elw++++k+++p +l  +++k+a++f+g
   Q: 693  TGLSNLGNTCFMNSSIQCVSNTQPLTQYFISgKHLYELNRTNPIGMKGHMAKCYGDLVQELWSGTQKNIAPLKLRWTIAKYAPRFNG 779
           7******************************99****************************************************** PP
   S: 87   yeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsde.....aeekkkkknkslisdlFqgqlksqikclecdnvssreep 168
           ++qqD+qE+laflld+l+e+l++ ++kp+ e++++d   ++d+     a+e++ ++n+s+++dlF+gql+sq+kc++c+++s+r++p
   Q: 780  FQQQDSQELLAFLLDGLHEDLNRVHDKPYVELKDSD--GRPDWevaaeAWENHLRRNRSIVVDLFHGQLRSQVKCKTCGHISVRFDP 864
           ********************************9999..6666666777*************************************** PP
   S: 169  fldlslpvpgkeetkke...................................................................... 185
           f+ lslp+p+++ +++e                                                                      
   Q: 865  FNFLSLPLPMDSYMHLEitvikldgstpvryglrlnmdekytglkkqlselcglkpeqillaevhssniknfpqdnqkvrlsvsgfl 951
           *************9999********************************************************************** PP
   S: 186  ....................................................................................... 185
                                                                                                  
   Q: 952  cafeipvpgsptsasspvqtdfstgpsangmlnimmngdfprptlipngmpntvvpcgtennlangmmngpmslfsespfigyiiav 1038
           *************************************************************************************** PP
   S: 186  ....................................................................................... 185
                                                                                                  
   Q: 1039 hrkmmrtelyflssqknrpslfgmplivpctvhtrkkdlydavwiqvsrlasplppqeasnhaqdcddsmgyqypftlrvvqkdgns 1125
           *************************************************************************************** PP
   S: 186  ...................................................................slqdcLesftkeeelegenk 205
                                                                              +l++cL++ft+eeel ++++
   Q: 1126 cawcpwyrfcrgckiecaedqayignasiavdwdptalhlryqtsqeriveehesveqsrraqaepiNLDSCLRAFTTEEELGEDEM 1212
           *************************************************************************************** PP
   S: 206  yycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefple.Ldlspfcts........................ 267
           yyc+kck ++ a+kkl+l++lP++Li+hLkRf+f +   + +k +k v+fp+e +d s f+++                        
   Q: 1213 YYCSKCKTHCLATKKLDLWRLPPILIIHLKRFQFVNG--RWIKSQKIVKFPREnFDPSAFLVQrdpshcqrkqltpqiddlsepril 1297
           ********************************99775..5569*******************9888888888888888888888888 PP
   S: 268  ....................................................................................... 267
                                                                                                  
   Q: 1298 qgeprkadlqntcasgegdslnrspslfntssilnnikaspspgrksgtscpsskssspnssprtlgrgkgrlrlpqigknklsnsk 1384
           888888888888888888888888888888888888888888777777777777777766666666666666666666666666655 PP
   S: 268  .......peekqke......................................................................... 274
                  +     +                                                                         
   Q: 1385 enldaskE-----Ngtdqeqklnsdqgdamskghvlggsqselfifqdemmlangyiceqnayshgsingvmdnhseeditddqrev 1466
           55555550.....05555556666667777777777777777777777777777777777777777777777777777888888888 PP
   S: 275  ..kkkYeLiavvvHsGslssGHYvayvknekgkWllfdDskVtevkeeevleetgstaYvlfYkrr 338
             + +Y+L+a+ +HsG +++GHYv+y+kn ++kW++++Ds+++e++ +e+ +   ++aY+lfY+++
   Q: 1467 csNPIYNLYAISCHSGIMGGGHYVTYAKNPNNKWYCYNDSSCKELHPDEIDT---DSAYILFYEQQ 1529
           88**************************************************...********985 PP

Organism

Pelodiscus sinensis

Protein Sequence
(Fasta)

MSQQCFIKEV LGDGVPPKVA EVIYCSFGGT SKGLHFNNLI VGLVLLTRGK DEEKAKYIFS 60
LFSNESGSYV VREEMERMLH IVDGKVPGSL KRCFLEGEKV NYEKFKNWLL QNKNAFTFSR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CAGCTAATAA ATTAAAGAAA TTGTGCAAAC ACTTTATCTA GCACTTTCGT TGTAAGACAA 60
AGTGATGTGC TTTTGAAGTT TTGACTTCTC TATGAAAGAA ATTCTTGATA GTGATGTTAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0106--Calcium
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR011992--EF-hand-dom_pair
IPR018247--EF_Hand_1_Ca_BS
IPR002048--EF_hand_dom
IPR006615--Pept_C19_DUSP
IPR001394--Peptidase_C19_UCH
IPR028135--Ub_USP-typ
IPR029071--Ubiquitin-rel_dom
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS51283--DUSP
PS00018--EF_HAND_1
PS50222--EF_HAND_2
PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF06337--DUSP
PF13202--EF-hand_5
PF14836--Ubiquitin_3
PF00443--UCH

SMART

SM00695--DUSP
SM00054--EFh

Gene Ontology

GO:0005829--C:cytosol
GO:0005794--C:Golgi apparatus
GO:0005509--F:calcium ion binding
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001611	Ailuropoda melanoleuca	85.92	0.00e+00	2366.00
IUUC-Apl-003272	Anas platyrhynchos	89.52	0.00e+00	2822.00
IUUC-Aca-005057	Anolis carolinensis	85.48	0.00e+00	2308.00
IUUC-Ame-010781	Astyanax mexicanus	75.68	0.00e+00	2352.00
IUUC-Bta-013502	Bos taurus	83.29	0.00e+00	2566.00
IUUC-Cja-018754	Callithrix jacchus	86.75	0.00e+00	2728.00
IUUC-Cfa-020526	Canis familiaris	87.28	0.00e+00	2734.00
IUUC-Cpo-021568	Cavia porcellus	82.82	0.00e+00	2511.00
IUUC-Csa-023143	Chlorocebus sabaeus	86.37	0.00e+00	2684.00
IUUC-Cho-024603	Choloepus hoffmanni	54.89	4.00e-162	565.00
IUUC-Cin-025583	Ciona intestinalis	50.39	0.00e+00	1228.00
IUUC-Csv-026344	Ciona savignyi	46.55	0.00e+00	1130.00
IUUC-Dre-028121	Danio rerio	76.78	0.00e+00	2315.00
IUUC-Dno-029911	Dasypus novemcinctus	86.03	0.00e+00	2704.00
IUUC-Dor-030608	Dipodomys ordii	58.16	0.00e+00	1018.00
IUUC-Dme-032094	Drosophila melanogaster	44.42	8.00e-125	442.00
IUUC-Ete-032639	Echinops telfairi	82.50	0.00e+00	1418.00
IUUC-Eca-034253	Equus caballus	87.01	0.00e+00	2744.00
IUUC-Eeu-035084	Erinaceus europaeus	78.74	0.00e+00	1478.00
IUUC-Fca-035474	Felis catus	85.69	0.00e+00	2252.00
IUUC-Fal-036985	Ficedula albicollis	87.55	0.00e+00	2737.00
IUUC-Gmo-039568	Gadus morhua	80.39	0.00e+00	2072.00
IUUC-Gga-040509	Gallus gallus	88.61	0.00e+00	2800.00
IUUC-Gac-041757	Gasterosteus aculeatus	80.69	0.00e+00	2132.00
IUUC-Ggo-044956	Gorilla gorilla	82.06	0.00e+00	1648.00
IUUC-Hsa-046107	Homo sapiens	87.07	0.00e+00	2717.00
IUUC-Itr-048865	Ictidomys tridecemlineatus	79.70	0.00e+00	1009.00
IUUC-Lch-050681	Latimeria chalumnae	79.10	0.00e+00	2443.00
IUUC-Loc-052474	Lepisosteus oculatus	77.32	0.00e+00	2424.00
IUUC-Laf-054273	Loxodonta africana	86.38	0.00e+00	2705.00
IUUC-Mcc-054718	Macaca mulatta	86.69	0.00e+00	2717.00
IUUC-Meu-056558	Macropus eugenii	70.27	0.00e+00	1319.00
IUUC-Mga-059892	Meleagris gallopavo	90.98	0.00e+00	2820.00
IUUC-Mmr-060866	Microcebus murinus	86.28	0.00e+00	2751.00
IUUC-Mdo-062607	Monodelphis domestica	89.04	0.00e+00	2823.00
IUUC-Mmu-063797	Mus musculus	86.44	0.00e+00	2749.00
IUUC-Mpu-066121	Mustela putorius furo	87.02	0.00e+00	2754.00
IUUC-Mlu-067581	Myotis lucifugus	85.54	0.00e+00	2740.00
IUUC-Nle-069916	Nomascus leucogenys	84.91	0.00e+00	2632.00
IUUC-Opr-071073	Ochotona princeps	78.25	0.00e+00	1079.00
IUUC-Ont-071310	Oreochromis niloticus	81.59	0.00e+00	2113.00
IUUC-Oan-073356	Ornithorhynchus anatinus	87.52	0.00e+00	2764.00
IUUC-Ocu-074216	Oryctolagus cuniculus	86.68	0.00e+00	2706.00
IUUC-Ola-087434	Oryzias latipes	81.05	0.00e+00	2072.00
IUUC-Oga-089034	Otolemur garnettii	86.61	0.00e+00	2701.00
IUUC-Oar-090369	Ovis aries	87.01	0.00e+00	2776.00
IUUC-Ptr-090605	Pan troglodytes	87.20	0.00e+00	2723.00
IUUC-Pan-092381	Papio anubis	86.59	0.00e+00	2710.00
IUUC-Pma-094480	Petromyzon marinus	64.19	0.00e+00	1449.00
IUUC-Pfo-096561	Poecilia formosa	80.82	0.00e+00	2073.00
IUUC-Pab-097643	Pongo abelii	86.96	0.00e+00	2674.00
IUUC-Pca-100944	Procavia capensis	70.85	0.00e+00	951.00
IUUC-Pva-102732	Pteropus vampyrus	77.31	0.00e+00	2363.00
IUUC-Rno-105113	Rattus norvegicus	86.44	0.00e+00	2727.00
IUUC-Sha-107608	Sarcophilus harrisii	80.76	9.00e-170	589.00
IUUC-Sar-113201	Sorex araneus	75.51	0.00e+00	1534.00
IUUC-Ssc-115469	Sus scrofa	77.27	5.00e-154	536.00
IUUC-Tgu-117322	Taeniopygia guttata	88.78	0.00e+00	2802.00
IUUC-Tru-118705	Takifugu rubripes	68.97	0.00e+00	680.00
IUUC-Tsy-119433	Tarsius syrichta	78.99	0.00e+00	1861.00
IUUC-Tni-120631	Tetraodon nigroviridis	77.89	0.00e+00	2120.00
IUUC-Tbe-127553	Tupaia belangeri	82.26	2.00e-176	613.00
IUUC-Ttr-128260	Tursiops truncatus	86.01	0.00e+00	2736.00
IUUC-Vpa-130479	Vicugna pacos	82.11	0.00e+00	2534.00
IUUC-Xtr-132686	Xenopus tropicalis	83.90	0.00e+00	2587.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence