iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Apl-003662

Ensembl Protein ID

ENSAPLP00000012479.1

UniProt Accession

U3IZ03; U3IZ03_ANAPL

Genbank Protein ID

ENSAPLP00000012479

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ADON01017387

Gene Name

HGS

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAPLG00000012661.1	ENSAPLT00000013220.1	ENSAPLP00000012479.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
UBD/Alpha-Helix/UIM	82.33	0.00e+00	991.00	IUUC-Bta-012506
UBD/Alpha-Helix/UIM	46.18	1.00e-94	344.00	IUUC-Dme-031952
UBD/Alpha-Helix/DUIM	81.79	0.00e+00	958.00	IUUC-Hsa-046009
UBD/Alpha-Helix/VHS	81.79	0.00e+00	958.00	IUUC-Hsa-046009
UBD/Alpha-Helix/UIM	81.07	0.00e+00	990.00	IUUC-Mmu-063952
UBD/Alpha-Helix/VHS	81.07	0.00e+00	986.00	IUUC-Rno-105125
UBD/Alpha-Helix/UIM	29.95	2.00e-23	105.00	IUUC-Sce-106192
UBD/Alpha-Helix/UIM	36.73	3.00e-34	141.00	IUUC-Spo-108220

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Anas platyrhynchos

Protein Sequence
(Fasta)

SGHGGGSFPV LLGVVRGRGS ILADLSSPRN MCSLSPSRAK YAVNAIKKKV NDKNPHVALY 60
ALEVMESVVK NCGQTVHDEV ANKQTMEELK EILKRQVEAS VRSKILNLIQ AWAHAFRNEP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TCCGGACACG GAGGTGGAAG TTTCCCAGTT TTACTGTAAA GTCCNNNNNN NNNNNNNNNN 60
NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR008942--ENTH_VHS
IPR024641--HRS_helical
IPR017073--Ubi-bd_Hrs_VPS27
IPR003903--UIM_dom
IPR002014--VHS_dom
IPR000306--Znf_FYVE
IPR017455--Znf_FYVE-rel
IPR011011--Znf_FYVE_PHD
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50330--UIM
PS50179--VHS
PS50178--ZF_FYVE

Pfam

PF01363--FYVE
PF12210--Hrs_helical
PF00790--VHS

SMART

SM00064--FYVE
SM00288--VHS

Gene Ontology

GO:0005829--C:cytosol
GO:0005769--C:early endosome
GO:0070062--C:extracellular exosome
GO:0005764--C:lysosome
GO:0046872--F:metal ion binding
GO:0010324--P:membrane invagination
GO:0046426--P:negative regulation of JAK-STAT cascade
GO:1903543--P:positive regulation of exosomal secretion
GO:0010628--P:positive regulation of gene expression
GO:0072657--P:protein localization to membrane
GO:0006622--P:protein targeting to lysosome
GO:0043405--P:regulation of MAP kinase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001518	Ailuropoda melanoleuca	81.23	0.00e+00	821.00
IUUC-Aca-004940	Anolis carolinensis	82.85	0.00e+00	1107.00
IUUC-Ago-007931	Ashbya gossypii	32.45	9.00e-25	108.00
IUUC-Acl-008274	Aspergillus clavatus	32.16	7.00e-35	142.00
IUUC-Afl-008521	Aspergillus flavus	31.80	6.00e-36	145.00
IUUC-Afu-008774	Aspergillus fumigatus	29.85	3.00e-35	143.00
IUUC-Ani-009445	Aspergillus nidulans	31.11	6.00e-37	148.00
IUUC-Ang-009863	Aspergillus niger	31.80	4.00e-37	149.00
IUUC-Ate-010444	Aspergillus terreus	31.32	2.00e-38	152.00
IUUC-Ame-011111	Astyanax mexicanus	76.01	0.00e+00	871.00
IUUC-Bgr-012087	Blumeria graminis	31.37	1.00e-38	154.00
IUUC-Bta-012506	Bos taurus	82.33	0.00e+00	992.00
IUUC-Bci-013782	Botrytis cinerea	30.77	4.00e-37	149.00
IUUC-Cel-018493	Caenorhabditis elegans	53.98	8.00e-58	218.00
IUUC-Cja-019998	Callithrix jacchus	79.58	0.00e+00	900.00
IUUC-Cfa-020615	Canis familiaris	79.78	0.00e+00	908.00
IUUC-Cpo-022019	Cavia porcellus	81.49	0.00e+00	1020.00
IUUC-Cre-022770	Chlamydomonas reinhardtii	42.65	2.00e-10	60.80
IUUC-Csa-023596	Chlorocebus sabaeus	81.49	0.00e+00	899.00
IUUC-Cin-025488	Ciona intestinalis	46.77	2.00e-115	409.00
IUUC-Csv-025802	Ciona savignyi	48.21	6.00e-105	374.00
IUUC-Cgl-026560	Colletotrichum gloeosporioides	34.71	3.00e-36	146.00
IUUC-Cne-026847	Cryptococcus neoformans	29.62	2.00e-32	133.00
IUUC-Dre-028353	Danio rerio	76.60	0.00e+00	874.00
IUUC-Dno-029005	Dasypus novemcinctus	79.02	0.00e+00	950.00
IUUC-Dor-030280	Dipodomys ordii	80.08	0.00e+00	970.00
IUUC-Dse-031238	Dothistroma septosporum	36.74	2.00e-39	157.00
IUUC-Dme-031952	Drosophila melanogaster	45.47	6.00e-87	315.00
IUUC-Ete-032235	Echinops telfairi	81.74	3.00e-107	382.00
IUUC-Eca-033873	Equus caballus	85.12	0.00e+00	979.00
IUUC-Eeu-034652	Erinaceus europaeus	79.21	2.00e-81	296.00
IUUC-Fca-036563	Felis catus	81.51	0.00e+00	944.00
IUUC-Fal-036649	Ficedula albicollis	92.88	0.00e+00	1093.00
IUUC-Fox-037962	Fusarium oxysporum	31.93	2.00e-35	143.00
IUUC-Fso-038396	Fusarium solani	33.06	3.00e-36	146.00
IUUC-Gmo-039510	Gadus morhua	76.15	0.00e+00	856.00
IUUC-Ggr-039938	Gaeumannomyces graminis	32.24	6.00e-35	142.00
IUUC-Gga-040201	Gallus gallus	90.31	0.00e+00	1113.00
IUUC-Gac-041459	Gasterosteus aculeatus	73.67	0.00e+00	889.00
IUUC-Ggo-044573	Gorilla gorilla	82.07	0.00e+00	962.00
IUUC-Hsa-046009	Homo sapiens	82.07	0.00e+00	1008.00
IUUC-Itr-049065	Ictidomys tridecemlineatus	81.93	0.00e+00	1039.00
IUUC-Kpa-049327	Komagataella pastoris	31.77	6.00e-28	119.00
IUUC-Lch-049944	Latimeria chalumnae	81.80	8.00e-161	559.00
IUUC-Loc-051850	Lepisosteus oculatus	79.23	0.00e+00	960.00
IUUC-Lma-053252	Leptosphaeria maculans	35.64	1.00e-36	148.00
IUUC-Laf-053346	Loxodonta africana	80.36	0.00e+00	865.00
IUUC-Mcc-055789	Macaca mulatta	81.91	0.00e+00	961.00
IUUC-Meu-056329	Macropus eugenii	70.96	1.00e-141	496.00
IUUC-Mor-057205	Magnaporthe oryzae	33.73	4.00e-35	142.00
IUUC-Mpo-057295	Magnaporthe poae	32.54	5.00e-37	149.00
IUUC-Mla-058849	Melampsora laricipopulina	32.99	4.00e-28	119.00
IUUC-Mga-059361	Meleagris gallopavo	92.37	0.00e+00	1075.00
IUUC-Mvi-060561	Microbotryum violaceum	31.28	3.00e-32	133.00
IUUC-Mmr-061122	Microcebus murinus	83.89	0.00e+00	875.00
IUUC-Mdo-062171	Monodelphis domestica	84.57	0.00e+00	1047.00
IUUC-Mmu-063952	Mus musculus	82.47	0.00e+00	1055.00
IUUC-Mpu-065852	Mustela putorius furo	81.68	0.00e+00	913.00
IUUC-Mlu-066996	Myotis lucifugus	76.34	1.00e-117	416.00
IUUC-Nfi-068539	Neosartorya fischeri	29.85	1.00e-35	144.00
IUUC-Ncr-068726	Neurospora crassa	39.01	4.00e-35	142.00
IUUC-Nle-070148	Nomascus leucogenys	76.63	0.00e+00	860.00
IUUC-Opr-070833	Ochotona princeps	64.59	1.00e-120	426.00
IUUC-Ont-071261	Oreochromis niloticus	75.31	0.00e+00	895.00
IUUC-Oan-073684	Ornithorhynchus anatinus	65.31	8.00e-141	493.00
IUUC-Ola-087570	Oryzias latipes	74.52	0.00e+00	887.00
IUUC-Oga-089087	Otolemur garnettii	85.95	0.00e+00	972.00
IUUC-Oar-089534	Ovis aries	82.19	0.00e+00	993.00
IUUC-Ptr-091654	Pan troglodytes	76.89	0.00e+00	863.00
IUUC-Pan-092652	Papio anubis	81.91	0.00e+00	962.00
IUUC-Pno-095125	Phaeosphaeria nodorum	37.57	5.00e-36	145.00
IUUC-Pfo-096757	Poecilia formosa	74.66	0.00e+00	862.00
IUUC-Pab-097788	Pongo abelii	81.28	0.00e+00	698.00
IUUC-Pca-100145	Procavia capensis	72.19	0.00e+00	761.00
IUUC-Pva-102965	Pteropus vampyrus	79.72	0.00e+00	927.00
IUUC-Pgr-103609	Puccinia graminis	34.43	7.00e-31	128.00
IUUC-Ptt-103865	Puccinia triticina	35.75	2.00e-31	130.00
IUUC-Pte-104095	Pyrenophora teres	34.95	9.00e-36	144.00
IUUC-Pyt-104668	Pyrenophora triticirepentis	35.11	9.00e-36	144.00
IUUC-Rno-105125	Rattus norvegicus	82.47	0.00e+00	982.00
IUUC-Sce-106192	Saccharomyces cerevisiae	29.73	1.00e-24	107.00
IUUC-Sha-107066	Sarcophilus harrisii	84.59	0.00e+00	1045.00
IUUC-Sja-107931	Schizosaccharomyces japonicus	32.73	9.00e-37	148.00
IUUC-Spo-108220	Schizosaccharomyces pombe	34.18	9.00e-36	144.00
IUUC-Stu-112464	Solanum tuberosum	45.90	5.00e-13	69.70
IUUC-Sar-113393	Sorex araneus	83.33	3.00e-88	319.00
IUUC-Sre-114986	Sporisorium reilianum	39.89	4.00e-37	149.00
IUUC-Tgu-117505	Taeniopygia guttata	89.48	0.00e+00	1019.00
IUUC-Tru-118494	Takifugu rubripes	75.28	0.00e+00	942.00
IUUC-Tsy-119626	Tarsius syrichta	97.80	7.00e-49	188.00
IUUC-Tni-120174	Tetraodon nigroviridis	74.07	0.00e+00	902.00
IUUC-Tre-122191	Trichoderma reesei	32.79	3.00e-36	146.00
IUUC-Tvi-122318	Trichoderma virens	32.38	2.00e-36	147.00
IUUC-Tme-126914	Tuber melanosporum	35.12	5.00e-40	159.00
IUUC-Ttr-129095	Tursiops truncatus	83.05	0.00e+00	1014.00
IUUC-Uma-129475	Ustilago maydis	36.96	4.00e-33	136.00
IUUC-Vda-129908	Verticillium dahliae	31.67	6.00e-32	132.00
IUUC-Xtr-131900	Xenopus tropicalis	77.93	0.00e+00	961.00
IUUC-Xma-133124	Xiphophorus maculatus	74.00	0.00e+00	894.00
IUUC-Yli-134682	Yarrowia lipolytica	32.43	2.00e-28	120.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence