iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Cpo-021655

Ensembl Protein ID

ENSCPOP00000016552.1

UniProt Accession

H0W0R4; H0W0R4_CAVPO

Genbank Protein ID

ENSCPOP00000016552

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAKN02057520

Gene Name

MED16

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCPOG00000022405.1	ENSCPOT00000024693.1	ENSCPOP00000016552.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.20e-06	27.8	67	100

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf..sdtllvsGsdDgtikvWDlrt 32
           gH++ +tcl++  s+ +l+s+  Dg+ik+W++ +
   Q: 67   GHSEAITCLEWdqSGSRLLSADADGQIKCWNMVD 100
           8**********965599**************866 PP

Organism

Cavia porcellus

Protein Sequence
(Fasta)

MDLAYVCEWE KWPKSTHCPS VPLACAWSCR NLIAFTTDLR NDDQDLTRMI HILDTEHPWD 60
VHSINSGHSE AITCLEWDQS GSRLLSADAD GQIKCWNMVD HLANSWESRV GSLVEGDPIV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGATCTGG CATACGTGTG CGAGTGGGAG AAATGGCCCA AGAGCACCCA CTGCCCCTCG 60
GTGCCCCTGG CCTGTGCATG GTCATGCCGA AACCTCATCG CCTTCACCAC GGACCTGCGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR021665--Mediator_Med16
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF11635--Med16

SMART

SM00320--WD40

Gene Ontology

GO:0016592--C:mediator complex
GO:0016020--C:membrane
GO:0004872--F:receptor activity
GO:0030375--F:thyroid hormone receptor coactivator activity
GO:0030521--P:androgen receptor signaling pathway
GO:0045893--P:positive regulation of transcription, DNA-templated
GO:0006367--P:transcription initiation from RNA polymerase II promoter

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ame-011407	Astyanax mexicanus	71.39	0.00e+00	1160.00
IUUC-Bta-012729	Bos taurus	90.46	0.00e+00	1474.00
IUUC-Cja-019000	Callithrix jacchus	94.02	1.00e-93	335.00
IUUC-Cfa-020876	Canis familiaris	92.87	0.00e+00	1526.00
IUUC-Dre-027473	Danio rerio	74.38	0.00e+00	1240.00
IUUC-Dno-029564	Dasypus novemcinctus	90.99	0.00e+00	1025.00
IUUC-Eca-033914	Equus caballus	93.88	0.00e+00	897.00
IUUC-Fca-036338	Felis catus	94.13	0.00e+00	832.00
IUUC-Fal-037249	Ficedula albicollis	84.82	0.00e+00	1452.00
IUUC-Gmo-039447	Gadus morhua	71.87	2.00e-166	578.00
IUUC-Gga-041100	Gallus gallus	84.71	0.00e+00	1361.00
IUUC-Gac-042603	Gasterosteus aculeatus	72.03	2.00e-159	555.00
IUUC-Ggo-044794	Gorilla gorilla	93.58	0.00e+00	1125.00
IUUC-Hsa-045722	Homo sapiens	92.81	0.00e+00	822.00
IUUC-Itr-048948	Ictidomys tridecemlineatus	93.59	0.00e+00	1517.00
IUUC-Loc-052871	Lepisosteus oculatus	77.58	0.00e+00	1274.00
IUUC-Mcc-055201	Macaca mulatta	94.22	0.00e+00	1128.00
IUUC-Mga-059807	Meleagris gallopavo	81.91	0.00e+00	1346.00
IUUC-Mmr-060781	Microcebus murinus	91.03	0.00e+00	1511.00
IUUC-Mpu-066388	Mustela putorius furo	92.74	0.00e+00	1514.00
IUUC-Ont-072316	Oreochromis niloticus	75.36	0.00e+00	1230.00
IUUC-Ola-086721	Oryzias latipes	73.47	0.00e+00	1185.00
IUUC-Oga-088875	Otolemur garnettii	94.24	0.00e+00	1515.00
IUUC-Oar-090444	Ovis aries	92.27	0.00e+00	1511.00
IUUC-Ptr-091117	Pan troglodytes	93.79	0.00e+00	807.00
IUUC-Pan-091807	Papio anubis	93.64	0.00e+00	1435.00
IUUC-Pfo-097356	Poecilia formosa	75.12	0.00e+00	1223.00
IUUC-Pab-097953	Pongo abelii	91.34	0.00e+00	1088.00
IUUC-Pca-100896	Procavia capensis	92.15	0.00e+00	1477.00
IUUC-Rno-105038	Rattus norvegicus	92.16	0.00e+00	1500.00
IUUC-Tgu-116750	Taeniopygia guttata	84.22	0.00e+00	1439.00
IUUC-Tru-118405	Takifugu rubripes	74.61	0.00e+00	1249.00
IUUC-Tni-120217	Tetraodon nigroviridis	76.95	0.00e+00	951.00
IUUC-Ttr-129222	Tursiops truncatus	92.15	0.00e+00	1481.00
IUUC-Xtr-132084	Xenopus tropicalis	80.63	0.00e+00	1275.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence