iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oga-088313

Ensembl Protein ID

ENSOGAP00000005429.2

UniProt Accession

H0WTF2; H0WTF2_OTOGA

Genbank Protein ID

ENSOGAP00000005429

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAQR03128667

Gene Name

NWD1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOGAG00000006070.2	ENSOGAT00000006074.2	ENSOGAP00000005429.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.90e-24	84.7	908	942
UBD/Beta-Prp	1.90e-52	178.3	862	1075

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtcla.f.sdtllvsGsdDgtikvWDlrtg 33
           gHt++v+c++ f  +tl +s+s+D+t+++W+l +g
   Q: 908  GHTGEVRCVKvFaKGTLAISASRDHTLRLWNLLSG 942
           8********9778669***************9776 PP

UBD/Beta-Prp

   S: 46   rslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqclee. 131
           ++l g+ +++ta+ +  ++ +lv g +D+++ vwd++  + +h l+gh+ +v++++++++g   +s+s+d t+r+w+l +gq+  + 
   Q: 862  ATLTGCHKGITAMAWGVEKMLLVIGTQDGIVAVWDMEEQQVIHLLTGHTGEVRCVKVFAKGTLAISASRDHTLRLWNLLSGQEKFTi 948
           688899999999999999999999999999999999999999999999999999999999999999999999999999999999888 PP
   S: 132  ....tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgec 214
               ++ +++  +++++v++ ++ +v ++  +++  W+l+t++l+ +  g+  d+  ++++  ++ +lv++s+ g v lw+   ge 
   Q: 949  wdggPQIPTEPQIWSLHVDE-AKKVVYSTSGSKISAWNLETAELVFRILGDTSDPWMCTAMLASQARLVTVSKGGVVSLWSSAMGEL 1034
           88888888888889999988.555566666788999999999999999998999999999999999999999999999999997777 PP
   S: 215  vrtlnght...dnvksvrfspnderlvsgssDgsiriWdlr 252
             +++  +   + +++v + +++  lv+g s gs+++  ++
   Q: 1035 HGKQHLSSikeEIPTCVVAVQKQGKLVTGFSNGSVSLVSSE 1075
           66665544444777777777788888888888888775555 PP

Organism

Otolemur garnettii

Protein Sequence
(Fasta)

MRRGKLCRAL PTLKCTFCQK HGLMFEVVDL RWGIQNTEAT DYLTTELCLE EVDRCRRTSI 60
GPSFVALIGD QYGPCTLPTL IEEKEWEALR AQLTARPSDL ELVARRFRRD ENAVPPTYIL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGCGGAGAG GGAAGCTCTG CAGAGCACTG CCTACCCTGA AGTGCAAACA TTCTGCCAGA 60
AGCACGGCTT GATGTTTGAG GTACAGGAAG TCACTGGGCT CCAGGCTCTG TTCAGTGCTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR027417--P-loop_NTPase
IPR011047--Quinoprotein_ADH-like_supfam
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

SMART

SM00320--WD40

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001525	Ailuropoda melanoleuca	83.95	0.00e+00	2393.00
IUUC-Apl-003467	Anas platyrhynchos	63.24	7.00e-68	249.00
IUUC-Ame-011400	Astyanax mexicanus	36.50	0.00e+00	897.00
IUUC-Bta-013223	Bos taurus	83.01	0.00e+00	2025.00
IUUC-Cel-018404	Caenorhabditis elegans	28.47	1.00e-100	362.00
IUUC-Cja-018773	Callithrix jacchus	82.84	0.00e+00	1366.00
IUUC-Cfa-020334	Canis familiaris	84.31	0.00e+00	2415.00
IUUC-Cpo-022316	Cavia porcellus	65.63	0.00e+00	1761.00
IUUC-Csa-023631	Chlorocebus sabaeus	85.20	0.00e+00	2396.00
IUUC-Cin-025646	Ciona intestinalis	31.87	9.00e-131	461.00
IUUC-Csv-026191	Ciona savignyi	25.25	1.00e-25	110.00
IUUC-Dre-028241	Danio rerio	35.78	0.00e+00	842.00
IUUC-Dno-029990	Dasypus novemcinctus	78.32	5.00e-138	484.00
IUUC-Dor-030869	Dipodomys ordii	59.87	2.00e-178	620.00
IUUC-Dme-032096	Drosophila melanogaster	21.61	1.00e-29	126.00
IUUC-Ete-033059	Echinops telfairi	85.71	0.00e+00	866.00
IUUC-Eca-033718	Equus caballus	79.08	0.00e+00	2251.00
IUUC-Fca-035748	Felis catus	82.69	0.00e+00	2421.00
IUUC-Gac-041507	Gasterosteus aculeatus	35.75	0.00e+00	766.00
IUUC-Ggo-044551	Gorilla gorilla	82.84	0.00e+00	2348.00
IUUC-Hsa-046787	Homo sapiens	84.41	0.00e+00	2402.00
IUUC-Itr-048104	Ictidomys tridecemlineatus	62.39	0.00e+00	1587.00
IUUC-Lch-049578	Latimeria chalumnae	48.34	0.00e+00	1344.00
IUUC-Loc-052039	Lepisosteus oculatus	41.96	0.00e+00	1150.00
IUUC-Laf-054240	Loxodonta africana	83.66	0.00e+00	2423.00
IUUC-Mcc-054657	Macaca mulatta	76.86	0.00e+00	2018.00
IUUC-Meu-056591	Macropus eugenii	64.08	0.00e+00	1174.00
IUUC-Mmr-061577	Microcebus murinus	80.95	0.00e+00	2305.00
IUUC-Mdo-062895	Monodelphis domestica	62.04	0.00e+00	1794.00
IUUC-Mmu-063866	Mus musculus	78.21	0.00e+00	2186.00
IUUC-Mpu-066510	Mustela putorius furo	83.25	0.00e+00	2399.00
IUUC-Mlu-067855	Myotis lucifugus	83.45	0.00e+00	2285.00
IUUC-Nle-069557	Nomascus leucogenys	79.62	0.00e+00	2199.00
IUUC-Opr-071196	Ochotona princeps	61.77	2.00e-179	623.00
IUUC-Ont-072070	Oreochromis niloticus	35.55	0.00e+00	741.00
IUUC-Oan-073437	Ornithorhynchus anatinus	57.64	0.00e+00	1273.00
IUUC-Ocu-074941	Oryctolagus cuniculus	82.73	1.00e-52	198.00
IUUC-Ola-086624	Oryzias latipes	32.85	2.00e-177	617.00
IUUC-Oar-090123	Ovis aries	82.04	0.00e+00	2327.00
IUUC-Ptr-090552	Pan troglodytes	84.39	0.00e+00	891.00
IUUC-Psi-093963	Pelodiscus sinensis	54.67	0.00e+00	1586.00
IUUC-Pfo-096197	Poecilia formosa	34.41	0.00e+00	743.00
IUUC-Pab-097755	Pongo abelii	83.75	0.00e+00	948.00
IUUC-Pca-100809	Procavia capensis	81.58	0.00e+00	1259.00
IUUC-Pva-102554	Pteropus vampyrus	79.82	0.00e+00	2228.00
IUUC-Rno-105174	Rattus norvegicus	70.36	0.00e+00	1885.00
IUUC-Sha-107304	Sarcophilus harrisii	62.74	0.00e+00	1839.00
IUUC-Sar-113168	Sorex araneus	65.79	0.00e+00	1401.00
IUUC-Tru-118251	Takifugu rubripes	35.47	0.00e+00	663.00
IUUC-Tsy-119276	Tarsius syrichta	80.07	2.00e-121	431.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence