iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSRNOG00000015131.6	ENSRNOT00000082303.1	ENSRNOP00000074117.1
ENSRNOG00000015131.6	ENSRNOT00000020323.3	ENSRNOP00000020323.2

Annotation

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
DNA & RNA Element
RAID2
Protein-protein Interaction
IID
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	3.90e-45	153.4	34	166

Active Site

Position(s)	Description	Evidence
114	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00388}

Domain Profile

E2/UBC

   S: 1    RlkkelkelekdppegisakpvdesdltewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltkifhPnvyenGkvClsilkee 89
           Rl++el++l+ +  +gisa p+++ +l++w  +i G ++t+Ye+  +kl++efp+ YP+++P+vkflt+++hPnv+++G++Cl+ilk  
   Q: 34   RLQQELMTLMMSGDKGISAFPESD-NLFKWVGTIHGAAGTVYEDLRYKLSLEFPSGYPYNAPTVKFLTPCYHPNVDTQGNICLDILK-- 119
           9***********************.9************************************************************9.. PP
   S: 90   ekWspalsvesvllsiqsllaepnpesplneeaaellkknreeykkkv 137
           +kWs+ ++v+++llsiqsll epn+espln++aael+k+   ++kk +
   Q: 120  DKWSALYDVRTILLSIQSLLGEPNIESPLNTHAAELWKNPT-AFKKYL 166
           ***********************************997655.488765 PP

Organism

Rattus norvegicus

Protein Sequence
(Fasta)

MASQNRDPAA ASVAAVRKGA EPCGGAARGP VGKRLQQELM TLMMSGDKGI SAFPESDNLF 60
KWVGTIHGAA GTVYEDLRYK LSLEFPSGYP YNAPTVKFLT PCYHPNVDTQ GNICLDILKD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AACCCAAGCG AGCCTCTGAT TGGCTAGCGC AGCAGGAGGG TTACAATTCA AACGCGGGCG 60
GCGGCCCGCA GCCCCGCAGT TGCTCTTTCC TCTCCACACG CTTGTCTCCG TGCCAGCACC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR000608--UBQ-conjugat_E2
IPR023313--UBQ-conjugating_AS
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS00183--UBIQUITIN_CONJUGAT_1
PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00179--UQ_con

Gene Ontology

GO:0005680--C:anaphase-promoting complex
GO:0005737--C:cytoplasm
GO:0005829--C:cytosol
GO:0005634--C:nucleus
GO:0005886--C:plasma membrane
GO:0005524--F:ATP binding
GO:0061631--F:ubiquitin conjugating enzyme activity
GO:0061630--F:ubiquitin protein ligase activity
GO:0031625--F:ubiquitin protein ligase binding
GO:0031145--P:anaphase-promoting complex-dependent catabolic process
GO:0010458--P:exit from mitosis
GO:0010994--P:free ubiquitin chain polymerization
GO:0031536--P:positive regulation of exit from mitosis
GO:0070979--P:protein K11-linked ubiquitination
GO:0070936--P:protein K48-linked ubiquitination
GO:0000209--P:protein polyubiquitination
GO:0030071--P:regulation of mitotic metaphase/anaphase transition

KEGG

rno:296368

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001924	Ailuropoda melanoleuca	95.03	9.00e-94	335.00
IUUC-Atr-002538	Amborella trichopoda	65.00	2.00e-52	198.00
IUUC-Aly-006086	Arabidopsis lyrata	58.79	2.00e-52	198.00
IUUC-Ath-006897	Arabidopsis thaliana	59.74	1.00e-51	195.00
IUUC-Acl-008223	Aspergillus clavatus	66.93	2.00e-39	155.00
IUUC-Afl-008675	Aspergillus flavus	54.82	2.00e-38	151.00
IUUC-Afu-008997	Aspergillus fumigatus	66.14	2.00e-38	151.00
IUUC-Ani-009470	Aspergillus nidulans	56.02	5.00e-39	153.00
IUUC-Ang-009648	Aspergillus niger	60.69	7.00e-39	153.00
IUUC-Aor-009977	Aspergillus oryzae	61.67	8.00e-32	129.00
IUUC-Ate-010318	Aspergillus terreus	52.60	7.00e-39	153.00
IUUC-Ame-011302	Astyanax mexicanus	76.47	1.00e-74	271.00
IUUC-Bta-013101	Bos taurus	96.65	8.00e-99	352.00
IUUC-Bci-013787	Botrytis cinerea	57.86	5.00e-45	173.00
IUUC-Bdi-014144	Brachypodium distachyon	68.57	1.00e-56	212.00
IUUC-Bol-015613	Brassica oleracea	57.99	5.00e-53	199.00
IUUC-Bra-017562	Brassica rapa	57.99	5.00e-53	199.00
IUUC-Cfa-020588	Canis familiaris	97.21	5.00e-96	342.00
IUUC-Cpo-021384	Cavia porcellus	97.21	5.00e-99	352.00
IUUC-Csa-023437	Chlorocebus sabaeus	96.09	3.00e-102	363.00
IUUC-Cho-024330	Choloepus hoffmanni	98.29	2.00e-67	246.00
IUUC-Cin-025365	Ciona intestinalis	56.88	1.00e-32	131.00
IUUC-Csv-025933	Ciona savignyi	60.92	1.00e-58	218.00
IUUC-Cgl-026494	Colletotrichum gloeosporioides	55.95	5.00e-45	173.00
IUUC-Cme-027266	Cyanidioschyzon merolae	52.60	6.00e-38	150.00
IUUC-Dre-027375	Danio rerio	76.47	9.00e-75	271.00
IUUC-Dno-029921	Dasypus novemcinctus	94.41	8.00e-93	332.00
IUUC-Dor-030209	Dipodomys ordii	94.97	5.00e-95	339.00
IUUC-Dse-031516	Dothistroma septosporum	54.67	4.00e-38	150.00
IUUC-Dme-031942	Drosophila melanogaster	67.83	5.00e-56	209.00
IUUC-Ete-032827	Echinops telfairi	83.67	1.00e-40	157.00
IUUC-Eca-034073	Equus caballus	97.77	2.00e-96	344.00
IUUC-Eeu-034854	Erinaceus europaeus	73.18	5.00e-67	246.00
IUUC-Fca-035666	Felis catus	97.77	2.00e-96	344.00
IUUC-Fal-037652	Ficedula albicollis	85.71	9.00e-53	197.00
IUUC-Fox-037793	Fusarium oxysporum	56.10	1.00e-44	172.00
IUUC-Fso-038151	Fusarium solani	56.10	3.00e-45	174.00
IUUC-Gmo-038894	Gadus morhua	77.22	2.00e-60	224.00
IUUC-Ggr-039730	Gaeumannomyces graminis	61.03	2.00e-35	141.00
IUUC-Gga-040537	Gallus gallus	86.03	7.00e-70	255.00
IUUC-Gac-041346	Gasterosteus aculeatus	72.47	1.00e-62	231.00
IUUC-Gma-043989	Glycine max	58.08	2.00e-54	204.00
IUUC-Ggo-045594	Gorilla gorilla	95.03	9.00e-101	358.00
IUUC-Hsa-046216	Homo sapiens	96.09	3.00e-102	363.00
IUUC-Hvu-047797	Hordeum vulgare	69.40	8.00e-54	202.00
IUUC-Itr-048402	Ictidomys tridecemlineatus	97.77	2.00e-96	344.00
IUUC-Kpa-049294	Komagataella pastoris	62.68	1.00e-47	182.00
IUUC-Lch-049761	Latimeria chalumnae	69.27	8.00e-71	259.00
IUUC-Lpe-051089	Leersia perrieri	64.10	6.00e-56	209.00
IUUC-Loc-052297	Lepisosteus oculatus	76.47	2.00e-72	265.00
IUUC-Lma-053214	Leptosphaeria maculans	50.97	3.00e-43	167.00
IUUC-Laf-054468	Loxodonta africana	95.03	2.00e-100	357.00
IUUC-Mcc-055338	Macaca mulatta	96.09	3.00e-102	363.00
IUUC-Meu-056147	Macropus eugenii	91.06	2.00e-92	331.00
IUUC-Mor-057239	Magnaporthe oryzae	58.11	5.00e-42	163.00
IUUC-Mpo-057491	Magnaporthe poae	62.50	5.00e-44	170.00
IUUC-Mtr-057687	Medicago truncatula	60.24	1.00e-48	185.00
IUUC-Mla-058880	Melampsora laricipopulina	65.00	1.00e-50	192.00
IUUC-Mga-059929	Meleagris gallopavo	85.71	2.00e-48	182.00
IUUC-Mvi-060528	Microbotryum violaceum	58.78	5.00e-46	177.00
IUUC-Mmr-060747	Microcebus murinus	97.52	3.00e-85	306.00
IUUC-Mdo-062343	Monodelphis domestica	92.78	2.00e-93	334.00
IUUC-Mmu-063563	Mus musculus	97.21	2.00e-98	350.00
IUUC-Mac-064823	Musa acuminata	64.54	2.00e-53	201.00
IUUC-Mpu-065746	Mustela putorius furo	96.13	2.00e-94	337.00
IUUC-Mlu-067388	Myotis lucifugus	95.03	3.00e-93	333.00
IUUC-Nfi-068577	Neosartorya fischeri	63.04	4.00e-39	153.00
IUUC-Ncr-068803	Neurospora crassa	55.21	2.00e-38	151.00
IUUC-Opr-070902	Ochotona princeps	93.89	3.00e-94	337.00
IUUC-Ont-071672	Oreochromis niloticus	69.71	4.00e-64	236.00
IUUC-Oan-073728	Ornithorhynchus anatinus	81.93	4.00e-38	148.00
IUUC-Ocu-074566	Oryctolagus cuniculus	92.78	5.00e-91	326.00
IUUC-Oba-075538	Oryza barthii	67.18	2.00e-51	194.00
IUUC-Obr-076757	Oryza brachyantha	69.57	6.00e-36	141.00
IUUC-Ogu-078467	Oryza glumaepatula	65.75	1.00e-55	208.00
IUUC-Oin-079533	Oryza indica	66.41	7.00e-51	192.00
IUUC-Olo-080673	Oryza longistaminata	67.94	5.00e-52	196.00
IUUC-Ome-081483	Oryza meridionalis	67.14	8.00e-55	206.00
IUUC-Oni-082321	Oryza nivara	65.75	1.00e-55	208.00
IUUC-Opu-083245	Oryza punctata	67.14	2.00e-54	204.00
IUUC-Oru-084641	Oryza rufipogon	62.99	7.00e-54	202.00
IUUC-Osa-085992	Oryza sativa	65.75	1.00e-55	208.00
IUUC-Ola-086807	Oryzias latipes	72.47	2.00e-71	261.00
IUUC-Olu-087834	Ostreococcus lucimarinus	69.34	1.00e-54	204.00
IUUC-Oga-088699	Otolemur garnettii	95.60	2.00e-101	360.00
IUUC-Oar-089542	Ovis aries	96.13	2.00e-94	337.00
IUUC-Ptr-091069	Pan troglodytes	96.09	3.00e-102	363.00
IUUC-Pan-092533	Papio anubis	95.03	6.00e-101	359.00
IUUC-Psi-093581	Pelodiscus sinensis	68.29	3.00e-58	217.00
IUUC-Pma-094607	Petromyzon marinus	72.35	1.00e-70	258.00
IUUC-Pno-094829	Phaeosphaeria nodorum	61.42	5.00e-43	166.00
IUUC-Ppa-095861	Physcomitrella patens	66.43	2.00e-55	208.00
IUUC-Pfo-096836	Poecilia formosa	70.11	1.00e-66	245.00
IUUC-Pab-098707	Pongo abelii	96.09	3.00e-102	363.00
IUUC-Pop-099021	Populus trichocarpa	67.14	2.00e-54	204.00
IUUC-Pca-100661	Procavia capensis	96.09	4.00e-98	349.00
IUUC-Ppe-101289	Prunus persica	57.14	1.00e-53	202.00
IUUC-Pva-103235	Pteropus vampyrus	92.74	7.00e-88	315.00
IUUC-Pte-104292	Pyrenophora teres	59.40	1.00e-43	168.00
IUUC-Sce-106133	Saccharomyces cerevisiae	62.02	3.00e-37	147.00
IUUC-Sha-107205	Sarcophilus harrisii	92.20	3.00e-76	277.00
IUUC-Sja-108009	Schizosaccharomyces japonicus	57.56	2.00e-51	194.00
IUUC-Spo-108136	Schizosaccharomyces pombe	56.40	9.00e-51	192.00
IUUC-Ssl-108394	Sclerotinia sclerotiorum	57.86	4.00e-45	174.00
IUUC-Smo-109014	Selaginella moellendorffii	65.44	3.00e-52	197.00
IUUC-Sit-110754	Setaria italica	66.43	5.00e-55	206.00
IUUC-Sly-111137	Solanum lycopersicum	66.20	9.00e-54	202.00
IUUC-Stu-112305	Solanum tuberosum	65.97	4.00e-54	203.00
IUUC-Sbi-114299	Sorghum bicolor	63.38	2.00e-51	194.00
IUUC-Ssc-115625	Sus scrofa	97.21	2.00e-96	344.00
IUUC-Tru-118289	Takifugu rubripes	77.91	2.00e-37	146.00
IUUC-Tni-120070	Tetraodon nigroviridis	73.28	7.00e-57	212.00
IUUC-Tca-121158	Theobroma cacao	67.14	3.00e-54	204.00
IUUC-Tre-121973	Trichoderma reesei	57.23	1.00e-44	172.00
IUUC-Tvi-122496	Trichoderma virens	57.83	4.00e-45	173.00
IUUC-Tae-123596	Triticum aestivum	65.75	5.00e-56	210.00
IUUC-Tur-126818	Triticum urartu	64.66	3.00e-42	163.00
IUUC-Tme-127044	Tuber melanosporum	66.42	1.00e-42	165.00
IUUC-Ttr-128548	Tursiops truncatus	75.98	3.00e-67	247.00
IUUC-Vda-129840	Verticillium dahliae	55.69	5.00e-44	170.00
IUUC-Vvi-131685	Vitis vinifera	61.45	8.00e-56	209.00
IUUC-Xtr-132953	Xenopus tropicalis	80.45	5.00e-83	299.00
IUUC-Xma-134093	Xiphophorus maculatus	70.11	1.00e-66	245.00
IUUC-Yli-134548	Yarrowia lipolytica	56.65	6.00e-51	192.00
IUUC-Zma-135182	Zea mays	65.71	3.00e-54	204.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence