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Basic Information Integrated Annotations
Tag Content
UUCD2 ID IUUC-Mmu-063957
UUCD1 version UUC-MuM-00639
Ensembl Protein ID ENSMUSP00000029106.6
UniProt Accession Q8BID6; A2AUD2; Q3U2R2; Q9D0G6; Q9D492; ZBT46_MOUSE
Genbank Protein ID BAB27633.1; BAB30386.1; BAC30190.1; BAE33078.1; CAM21496.1; AAH58179.1
Protein Name Zinc finger and BTB domain-containing protein 46; BTB-ZF protein expressed in effector lymphocytes; BTB/POZ domain-containing protein 4
Genbank Nucleotide ID AK011461; AK016700; AK038975; AK155148; AL929094; BC058179
Gene Name Zbtb46; Btbd4
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSMUSG00000027583.13 ENSMUST00000029106.12 ENSMUSP00000029106.6
ENSMUSG00000027583.13 ENSMUST00000087409.9 ENSMUSP00000084672.3
Annotation
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpressGXD
DNA & RNA Element
AREsitemicroRNATRANSFACmiRNAMap
RAID2
Protein-protein Interaction
IIDiRefIndexPINAHINT
Mentha
Post-translational Modifications (PTMs)
CPLMdbPAFPhosphositePlusdbPTM
Protein Expression/Proteomics
GPMDB
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/BCR/BTB_Other: BTB 1.10e-10 42.8 31 97
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/BCR/BTB_Other: BTB
   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikd.vqpevfrallkFlYtgklde 67
           +D ++vv+g++f+ahk vL  sS++F+ l  +  + s++   +++ d v ++ f+a+++F+Y+  l +
   Q: 31   CDACVVVEGKVFKAHKNVLLGSSRYFKTLYCQVQKTSDQATVTHL-DiVTAQGFKAIIDFMYSAHLAL 97
           8*****************************999898884555555.55**************998865 PP
   
Organism Mus musculus
Functional Description
(View)

Functional Description


     Function as a transcriptional repressor for PRDM1.
 Function as a transcriptional repressor for PRDM1.
Protein Sequence
(Fasta)
MNNRKEDMEI TSHYRHLLRE LNEQRQHGVL CDACVVVEGK VFKAHKNVLL GSSRYFKTLY 60
CQVQKTSDQA TVTHLDIVTA QGFKAIIDFM YSAHLALTSR NVIEVMSAAS FLQMTDIVQA 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Mmu-063957|E3,BTB_Other|Mus musculus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
GCGGGGGCGC GCGCCGGCCT GACGGACGGA CGAACGGACT GGCGGGCGGA CCAAGCCACC 60
CGAGCGAGCG CGCAGCTCGG ACCCTCCCGG ACGCAGCTCT CGCCAGTGGC CGCGCGATCA 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Mmu-063957|E3,BTB_Other|Mus musculus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0025--Alternative splicing
KW-0181--Complete proteome
KW-1017--Isopeptide bond
KW-0479--Metal-binding
KW-0539--Nucleus
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0677--Repeat
KW-0804--Transcription
KW-0805--Transcription regulation
KW-0832--Ubl conjugation
KW-0862--Zinc
KW-0863--Zinc-finger
Interpro

IPR000210--BTB/POZ_dom
IPR004039--Rubredoxin-type_fold
IPR011333--SKP1/BTB/POZ
IPR013087--Znf_C2H2_type
IPR013083--Znf_RING/FYVE/PHD
PROSITE

PS50097--BTB
PS00028--ZINC_FINGER_C2H2_1
PS50157--ZINC_FINGER_C2H2_2
Pfam

PF00651--BTB
SMART

SM00225--BTB
SM00355--ZnF_C2H2
Gene Ontology

GO:0005634--C:nucleus
GO:0046872--F:metal ion binding
GO:0003676--F:nucleic acid binding
GO:2001199--P:negative regulation of dendritic cell differentiation
GO:0030853--P:negative regulation of granulocyte differentiation
GO:0045650--P:negative regulation of macrophage differentiation
GO:0045656--P:negative regulation of monocyte differentiation
GO:2001200--P:positive regulation of dendritic cell differentiation
GO:0006355--P:regulation of transcription, DNA-templated
GO:0006351--P:transcription, DNA-templated
KEGG mmu:72147
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-002267 Ailuropoda melanoleuca 91.21 0.00e+00 933.00
IUUC-Apl-004220 Anas platyrhynchos 81.36 0.00e+00 971.00
IUUC-Aca-005350 Anolis carolinensis 77.50 0.00e+00 939.00
IUUC-Ame-011334 Astyanax mexicanus 61.14 0.00e+00 714.00
IUUC-Bta-012773 Bos taurus 83.67 0.00e+00 954.00
IUUC-Cja-019261 Callithrix jacchus 77.36 0.00e+00 884.00
IUUC-Cfa-021070 Canis familiaris 91.89 0.00e+00 768.00
IUUC-Cpo-021350 Cavia porcellus 92.50 0.00e+00 1053.00
IUUC-Csa-023182 Chlorocebus sabaeus 92.07 0.00e+00 1018.00
IUUC-Cin-025354 Ciona intestinalis 38.40 6.00e-22 99.40
IUUC-Csv-026323 Ciona savignyi 40.00 1.00e-22 101.00
IUUC-Dre-027453 Danio rerio 62.32 0.00e+00 716.00
IUUC-Dno-029375 Dasypus novemcinctus 85.81 0.00e+00 687.00
IUUC-Dor-030991 Dipodomys ordii 70.95 0.00e+00 800.00
IUUC-Eca-033346 Equus caballus 91.95 0.00e+00 991.00
IUUC-Eeu-034489 Erinaceus europaeus 86.00 0.00e+00 714.00
IUUC-Fca-035853 Felis catus 86.50 0.00e+00 985.00
IUUC-Fal-037546 Ficedula albicollis 79.67 0.00e+00 942.00
IUUC-Gmo-038589 Gadus morhua 82.67 1.00e-72 265.00
IUUC-Gga-040354 Gallus gallus 80.90 0.00e+00 951.00
IUUC-Ggo-045007 Gorilla gorilla 91.64 0.00e+00 1006.00
IUUC-Hsa-046360 Homo sapiens 91.70 0.00e+00 1014.00
IUUC-Itr-048566 Ictidomys tridecemlineatus 89.67 0.00e+00 1029.00
IUUC-Lch-050668 Latimeria chalumnae 76.37 0.00e+00 892.00
IUUC-Loc-052410 Lepisosteus oculatus 69.33 0.00e+00 813.00
IUUC-Laf-054523 Loxodonta africana 88.37 0.00e+00 959.00
IUUC-Mcc-055030 Macaca mulatta 93.44 0.00e+00 978.00
IUUC-Meu-056772 Macropus eugenii 81.00 0.00e+00 1005.00
IUUC-Mga-059531 Meleagris gallopavo 79.57 0.00e+00 928.00
IUUC-Mmr-061653 Microcebus murinus 83.69 0.00e+00 995.00
IUUC-Mdo-062023 Monodelphis domestica 82.17 0.00e+00 1026.00
IUUC-Mpu-065784 Mustela putorius furo 86.67 0.00e+00 987.00
IUUC-Mlu-067188 Myotis lucifugus 81.83 0.00e+00 970.00
IUUC-Nle-069839 Nomascus leucogenys 91.23 0.00e+00 914.00
IUUC-Ont-071549 Oreochromis niloticus 61.42 0.00e+00 711.00
IUUC-Oan-073288 Ornithorhynchus anatinus 79.13 0.00e+00 1008.00
IUUC-Ocu-074031 Oryctolagus cuniculus 66.23 0.00e+00 707.00
IUUC-Ola-087013 Oryzias latipes 61.11 0.00e+00 711.00
IUUC-Oga-089158 Otolemur garnettii 85.19 0.00e+00 970.00
IUUC-Oar-090145 Ovis aries 81.41 0.00e+00 769.00
IUUC-Ptr-090525 Pan troglodytes 90.59 0.00e+00 998.00
IUUC-Pan-092450 Papio anubis 92.25 0.00e+00 1020.00
IUUC-Psi-093791 Pelodiscus sinensis 80.67 0.00e+00 984.00
IUUC-Pfo-096728 Poecilia formosa 58.11 0.00e+00 691.00
IUUC-Pab-098690 Pongo abelii 93.21 0.00e+00 941.00
IUUC-Pva-103107 Pteropus vampyrus 85.05 0.00e+00 694.00
IUUC-Rno-104885 Rattus norvegicus 98.84 0.00e+00 1165.00
IUUC-Sha-107445 Sarcophilus harrisii 82.17 0.00e+00 1017.00
IUUC-Sar-113744 Sorex araneus 78.87 5.00e-173 600.00
IUUC-Tgu-117181 Taeniopygia guttata 83.30 0.00e+00 941.00
IUUC-Tru-117668 Takifugu rubripes 61.44 0.00e+00 705.00
IUUC-Tsy-119528 Tarsius syrichta 93.44 1.00e-166 579.00
IUUC-Tni-120403 Tetraodon nigroviridis 81.69 4.00e-66 245.00
IUUC-Tbe-128061 Tupaia belangeri 72.97 5.00e-167 580.00
IUUC-Ttr-128681 Tursiops truncatus 89.27 0.00e+00 819.00
Created Date 25-Jun-2017

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