iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mga-059876

Ensembl Protein ID

ENSMGAP00000015443.1

UniProt Accession

G1NP17; G1NP17_MELGA

Protein Name

tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit WDR4; WD repeat-containing protein 4

Gene Name

WDR4

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMGAG00000014580.1	ENSMGAT00000016399.1	ENSMGAP00000015443.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	4.40e-06	26.6	157	194

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf..sd..tllvsGsdDgtikvWDlrtgvl 35
           gH++ v+ + f  ++  +ll+s+s+D+t+++W + tg  
   Q: 157  GHEEFVSRI-FvvPNypDLLLSASGDCTLRLWKYETGEE 194
           566667777.778444799**************999875 PP

Organism

Meleagris gallopavo

Functional Description
(View)

Required for the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. In the complex, it is required to stabilize and induce conformational changes of the catalytic subunit.

Protein Sequence
(Fasta)

DDALFVYDCA NVEKKALGNK GQDGQPADKG SDNILAFAFS PSGDYFVLTD DNKQLILFRT 60
KPSWECISIR SVNRRCTSLV ITAAEDKILV ADKSGDVYSY SITEPQAEGK FELGHLSMLL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GATGATGCTC TCTTCGTGTA TGACTGTGCC AATGTGGAAA AGAAGGCCTT AGGAAATAAA 60
GGGTGAGAAA ATAAGTGTAG ATATATGGCG TTTTCCTTGA TGGTGCATCT GTCCCTCAGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0677--Repeat
KW-0819--tRNA processing
KW-0853--WD repeat

Interpro

IPR028884--Trm82
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0005829--C:cytosol
GO:0005654--C:nucleoplasm
GO:0008176--F:tRNA (guanine-N7-)-methyltransferase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000556	Aegilops tauschii	23.55	3.00e-09	56.20
IUUC-Apl-003975	Anas platyrhynchos	85.83	0.00e+00	632.00
IUUC-Aca-005170	Anolis carolinensis	68.11	3.00e-131	461.00
IUUC-Aly-005769	Arabidopsis lyrata	29.48	2.00e-25	109.00
IUUC-Ath-006733	Arabidopsis thaliana	27.48	2.00e-24	106.00
IUUC-Acl-008151	Aspergillus clavatus	24.40	1.00e-13	70.50
IUUC-Afl-008518	Aspergillus flavus	42.70	1.00e-12	67.00
IUUC-Afu-009102	Aspergillus fumigatus	29.54	2.00e-13	70.10
IUUC-Ani-009442	Aspergillus nidulans	27.71	4.00e-13	69.30
IUUC-Aor-010133	Aspergillus oryzae	29.02	5.00e-15	75.50
IUUC-Ate-010465	Aspergillus terreus	30.04	4.00e-15	75.50
IUUC-Ame-010613	Astyanax mexicanus	45.57	2.00e-90	325.00
IUUC-Bgr-012067	Blumeria graminis	34.01	5.00e-16	78.60
IUUC-Bta-012788	Bos taurus	57.45	2.00e-124	438.00
IUUC-Bdi-014458	Brachypodium distachyon	29.55	1.00e-15	77.40
IUUC-Bol-016398	Brassica oleracea	29.57	5.00e-26	111.00
IUUC-Bra-016644	Brassica rapa	35.20	3.00e-23	103.00
IUUC-Cpo-021963	Cavia porcellus	56.32	3.00e-115	407.00
IUUC-Csa-024148	Chlorocebus sabaeus	57.41	9.00e-107	379.00
IUUC-Cne-026834	Cryptococcus neoformans	38.89	8.00e-21	94.70
IUUC-Dre-028427	Danio rerio	45.91	3.00e-96	344.00
IUUC-Dno-028881	Dasypus novemcinctus	50.52	8.00e-112	396.00
IUUC-Dor-030522	Dipodomys ordii	55.31	6.00e-123	433.00
IUUC-Dme-032136	Drosophila melanogaster	38.86	2.00e-24	106.00
IUUC-Fca-035833	Felis catus	56.88	2.00e-127	448.00
IUUC-Fal-037497	Ficedula albicollis	80.65	6.00e-171	592.00
IUUC-Gga-040547	Gallus gallus	93.92	0.00e+00	711.00
IUUC-Gac-041761	Gasterosteus aculeatus	43.73	6.00e-81	293.00
IUUC-Gma-043722	Glycine max	29.93	1.00e-23	103.00
IUUC-Ggo-045340	Gorilla gorilla	57.22	8.00e-115	406.00
IUUC-Hsa-046403	Homo sapiens	59.36	4.00e-114	404.00
IUUC-Hvu-047643	Hordeum vulgare	26.88	3.00e-18	85.50
IUUC-Itr-048103	Ictidomys tridecemlineatus	57.89	5.00e-124	437.00
IUUC-Kpa-049283	Komagataella pastoris	35.66	7.00e-19	87.80
IUUC-Lch-050682	Latimeria chalumnae	53.93	1.00e-115	409.00
IUUC-Lpe-050712	Leersia perrieri	27.45	5.00e-23	101.00
IUUC-Loc-052599	Lepisosteus oculatus	54.67	4.00e-123	434.00
IUUC-Laf-054390	Loxodonta africana	56.05	8.00e-128	449.00
IUUC-Mcc-054747	Macaca mulatta	57.67	5.00e-115	407.00
IUUC-Mtr-058600	Medicago truncatula	32.37	6.00e-27	114.00
IUUC-Mla-059129	Melampsora laricipopulina	26.88	1.00e-11	63.50
IUUC-Mvi-060359	Microbotryum violaceum	30.67	5.00e-11	62.40
IUUC-Mmr-061518	Microcebus murinus	58.19	1.00e-118	419.00
IUUC-Mac-065625	Musa acuminata	27.64	2.00e-21	96.30
IUUC-Nfi-068402	Neosartorya fischeri	27.35	2.00e-12	67.00
IUUC-Nle-069914	Nomascus leucogenys	53.44	3.00e-107	381.00
IUUC-Ont-071555	Oreochromis niloticus	44.89	2.00e-83	301.00
IUUC-Oan-072951	Ornithorhynchus anatinus	60.95	1.00e-136	478.00
IUUC-Ocu-074679	Oryctolagus cuniculus	56.89	2.00e-115	408.00
IUUC-Oba-075355	Oryza barthii	24.87	4.00e-14	72.40
IUUC-Obr-076769	Oryza brachyantha	29.46	5.00e-25	108.00
IUUC-Ogl-077168	Oryza glaberrima	27.68	9.00e-25	107.00
IUUC-Ogu-078275	Oryza glumaepatula	24.87	1.00e-13	70.90
IUUC-Oin-079207	Oryza indica	27.68	9.00e-25	107.00
IUUC-Oni-082437	Oryza nivara	25.00	3.00e-14	72.40
IUUC-Opu-084031	Oryza punctata	27.75	7.00e-23	101.00
IUUC-Oru-084380	Oryza rufipogon	24.87	3.00e-13	69.70
IUUC-Osa-085327	Oryza sativa	27.42	5.00e-24	104.00
IUUC-Ola-086716	Oryzias latipes	39.94	3.00e-71	261.00
IUUC-Olu-087708	Ostreococcus lucimarinus	30.11	3.00e-15	75.50
IUUC-Oar-090239	Ovis aries	58.31	3.00e-122	431.00
IUUC-Ptr-090851	Pan troglodytes	57.22	4.00e-115	407.00
IUUC-Pan-092558	Papio anubis	55.53	3.00e-106	378.00
IUUC-Psi-093792	Pelodiscus sinensis	73.90	2.00e-155	541.00
IUUC-Ppa-095757	Physcomitrella patens	29.62	3.00e-18	85.90
IUUC-Pfo-096465	Poecilia formosa	43.45	1.00e-88	319.00
IUUC-Pab-097722	Pongo abelii	57.14	5.00e-118	417.00
IUUC-Pop-098979	Populus trichocarpa	33.69	5.00e-18	85.10
IUUC-Pca-100753	Procavia capensis	52.96	3.00e-90	325.00
IUUC-Ppe-101515	Prunus persica	26.22	6.00e-20	91.30
IUUC-Sja-107780	Schizosaccharomyces japonicus	29.65	9.00e-14	70.90
IUUC-Spo-108251	Schizosaccharomyces pombe	27.00	1.00e-12	67.00
IUUC-Smo-108938	Selaginella moellendorffii	32.74	2.00e-19	89.70
IUUC-Sit-110020	Setaria italica	26.65	4.00e-22	98.60
IUUC-Sly-111543	Solanum lycopersicum	27.33	2.00e-21	96.70
IUUC-Stu-111925	Solanum tuberosum	26.67	3.00e-20	92.40
IUUC-Sbi-114061	Sorghum bicolor	32.26	6.00e-23	101.00
IUUC-Tgu-117321	Taeniopygia guttata	79.53	3.00e-159	553.00
IUUC-Tru-118454	Takifugu rubripes	44.02	3.00e-81	294.00
IUUC-Tni-119894	Tetraodon nigroviridis	39.84	4.00e-76	277.00
IUUC-Tca-121746	Theobroma cacao	31.39	3.00e-20	92.40
IUUC-Tae-124114	Triticum aestivum	26.63	3.00e-17	82.40
IUUC-Tur-126254	Triticum urartu	23.90	3.00e-11	62.40
IUUC-Tbe-127683	Tupaia belangeri	71.60	2.00e-33	136.00
IUUC-Ttr-129056	Tursiops truncatus	53.49	6.00e-114	403.00
IUUC-Vvi-131428	Vitis vinifera	31.17	1.00e-20	93.60
IUUC-Xma-133605	Xiphophorus maculatus	45.33	6.00e-91	327.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence