iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ate-010530

Ensembl Protein ID

CADATEAP00009500

UniProt Accession

Q0CQ54; HIR1_ASPTN

Genbank Protein ID

EAU35982.1

Protein Name

Protein hir1

Genbank Nucleotide ID

CH476598

Gene Name

ATEG_04180; hir1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
CADATEAG00009500	CADATEAT00009500	CADATEAP00009500

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	7.20e-22	75.7	166	198
UBD/Beta-Prp	6.90e-45	152.5	43	197

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdDgtikvWDlrt 32
           H++ v ++ f +  ++++++sdD t+k++++++
   Q: 166  HQSHVKGITFdPAnKYFATASDDRTVKIFRFTS 198
           9999******9444***************9876 PP

UBD/Beta-Prp

   S: 13   itcvkfspdksllatgsrdgtikvwdvttgkl..........lrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghed 95
           +++ ++spd+s l+t+  dg +++w+++              l+s+s+h++++ +v+fsp+gk+l++g++D++++++ l+++++ h+  g   
   Q: 43   VYSCDVSPDGSRLVTAAGDGYVRIWSTEAIRNtddssqkpkqLASMSNHSGTIHTVRFSPNGKYLASGADDKIVCIYTLDANPPSHSTFG--- 132
           455666777777777777777777777665556777777777777777777777777777777777777777777777776666666663... PP
   S: 96   svlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsf 188
                 +s +++ lvs + d+ + vw  +t ++l+ tls+h++ v +++++p +++++++s+Drtv++++                       
   Q: 133  ------WSYDSSILVSVGLDSKVVVWSGHTFEKLK-TLSVHQSHVKGITFDPANKYFATASDDRTVKIFRF---------------------- 196
           ......33333557777777777777777777776.77777777777777777777777777777777765...................... PP
   S: 189  dsngkelvsgsldgtvklwdlq 210
                                 
   Q: 197  ---------------------T 197
           .....................3 PP

Organism

Aspergillus terreus

Functional Description
(View)

Required for replication-independent chromatin assembly and for the periodic repression of histone gene transcription during the cell cycle.

Protein Sequence
(Fasta)

MHIIKPVWLT HGGKLVVHDS SSSWHGPLTP TLLSTGERKD FEVYSCDVSP DGSRLVTAAG 60
DGYVRIWSTE AIRNTDDSSQ KPKQLASMSN HSGTIHTVRF SPNGKYLASG ADDKIVCIYT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGCATATTA TCAAGCCCGT TTGGCTCACC CACGGGGGTA AGTTGGTCGT GCACGATTCC 60
TCGAGTTCCT GGCATGGTCC ACTAACTCCT ACTCTTCTTT CTACAGGCGA ACGGAAAGAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0156--Chromatin regulator
KW-0181--Complete proteome
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0677--Repeat
KW-0678--Repressor
KW-0804--Transcription
KW-0805--Transcription regulation
KW-0853--WD repeat

Interpro

IPR031120--HIR1
IPR011494--Hira
IPR019015--HIRA_B_motif
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF07569--Hira
PF09453--HIRA_B
PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0005634--C:nucleus
GO:0016569--P:covalent chromatin modification
GO:0006355--P:regulation of transcription, DNA-templated
GO:0006351--P:transcription, DNA-templated

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-001039	Aegilops tauschii	26.67	1.00e-50	193.00
IUUC-Aml-001723	Ailuropoda melanoleuca	30.75	2.00e-49	189.00
IUUC-Atr-003132	Amborella trichopoda	27.57	6.00e-53	201.00
IUUC-Apl-003197	Anas platyrhynchos	27.94	9.00e-51	193.00
IUUC-Aca-004733	Anolis carolinensis	27.85	6.00e-53	201.00
IUUC-Aly-005446	Arabidopsis lyrata	26.55	1.00e-49	189.00
IUUC-Ath-007627	Arabidopsis thaliana	26.64	3.00e-54	205.00
IUUC-Ago-007766	Ashbya gossypii	30.51	7.00e-107	379.00
IUUC-Acl-008104	Aspergillus clavatus	82.30	0.00e+00	1734.00
IUUC-Afl-008591	Aspergillus flavus	80.94	0.00e+00	1688.00
IUUC-Afu-008781	Aspergillus fumigatus	83.28	0.00e+00	1663.00
IUUC-Ani-009272	Aspergillus nidulans	87.19	0.00e+00	1710.00
IUUC-Ang-009655	Aspergillus niger	83.95	0.00e+00	1747.00
IUUC-Aor-010119	Aspergillus oryzae	80.94	0.00e+00	1689.00
IUUC-Bgr-012237	Blumeria graminis	57.95	0.00e+00	1069.00
IUUC-Bta-013320	Bos taurus	30.75	9.00e-50	190.00
IUUC-Bci-013795	Botrytis cinerea	54.49	0.00e+00	1134.00
IUUC-Bdi-014075	Brachypodium distachyon	28.85	5.00e-55	207.00
IUUC-Bol-016440	Brassica oleracea	29.03	4.00e-56	211.00
IUUC-Bra-016651	Brassica rapa	28.99	4.00e-56	211.00
IUUC-Cel-018692	Caenorhabditis elegans	24.71	2.00e-26	113.00
IUUC-Cja-018987	Callithrix jacchus	27.86	7.00e-45	174.00
IUUC-Cfa-020132	Canis familiaris	30.75	2.00e-49	189.00
IUUC-Cpo-021484	Cavia porcellus	29.81	7.00e-51	194.00
IUUC-Cre-022846	Chlamydomonas reinhardtii	28.50	3.00e-42	165.00
IUUC-Csa-023081	Chlorocebus sabaeus	26.80	3.00e-52	198.00
IUUC-Cin-025182	Ciona intestinalis	29.50	1.00e-50	193.00
IUUC-Csv-026154	Ciona savignyi	30.53	2.00e-49	189.00
IUUC-Cgl-026655	Colletotrichum gloeosporioides	52.46	0.00e+00	1071.00
IUUC-Cne-026891	Cryptococcus neoformans	36.39	1.00e-72	266.00
IUUC-Cme-027349	Cyanidioschyzon merolae	24.65	3.00e-26	112.00
IUUC-Dre-027655	Danio rerio	28.78	9.00e-52	197.00
IUUC-Dor-030687	Dipodomys ordii	30.40	2.00e-44	172.00
IUUC-Dse-031334	Dothistroma septosporum	54.92	0.00e+00	1102.00
IUUC-Dme-031746	Drosophila melanogaster	28.70	4.00e-50	191.00
IUUC-Ete-032384	Echinops telfairi	24.85	9.00e-35	140.00
IUUC-Eca-033430	Equus caballus	27.25	7.00e-49	187.00
IUUC-Fca-036121	Felis catus	30.75	2.00e-49	189.00
IUUC-Fal-036817	Ficedula albicollis	28.00	9.00e-51	193.00
IUUC-Fox-037906	Fusarium oxysporum	56.26	0.00e+00	717.00
IUUC-Fso-038409	Fusarium solani	52.97	0.00e+00	1090.00
IUUC-Gmo-039151	Gadus morhua	29.33	3.00e-53	201.00
IUUC-Ggr-040016	Gaeumannomyces graminis	54.09	0.00e+00	1119.00
IUUC-Gga-040936	Gallus gallus	27.21	1.00e-51	196.00
IUUC-Gac-041405	Gasterosteus aculeatus	28.40	5.00e-50	191.00
IUUC-Gma-042800	Glycine max	27.84	1.00e-54	206.00
IUUC-Ggo-045430	Gorilla gorilla	26.80	4.00e-52	198.00
IUUC-Hsa-046442	Homo sapiens	26.80	5.00e-52	197.00
IUUC-Hvu-047587	Hordeum vulgare	29.05	1.00e-47	183.00
IUUC-Itr-048910	Ictidomys tridecemlineatus	30.67	9.00e-36	142.00
IUUC-Kpa-049145	Komagataella pastoris	41.03	3.00e-99	354.00
IUUC-Lch-050474	Latimeria chalumnae	29.37	5.00e-50	191.00
IUUC-Lpe-051209	Leersia perrieri	28.57	4.00e-48	184.00
IUUC-Loc-052119	Lepisosteus oculatus	26.51	3.00e-49	189.00
IUUC-Lma-053237	Leptosphaeria maculans	56.85	0.00e+00	1167.00
IUUC-Laf-053718	Loxodonta africana	27.91	3.00e-53	201.00
IUUC-Mcc-055621	Macaca mulatta	27.63	2.00e-44	172.00
IUUC-Meu-055914	Macropus eugenii	30.43	1.00e-31	130.00
IUUC-Mor-057090	Magnaporthe oryzae	53.80	0.00e+00	1106.00
IUUC-Mpo-057364	Magnaporthe poae	54.26	0.00e+00	1120.00
IUUC-Mtr-057744	Medicago truncatula	27.73	3.00e-52	198.00
IUUC-Mla-058914	Melampsora laricipopulina	26.71	3.00e-74	271.00
IUUC-Mga-060181	Meleagris gallopavo	28.09	2.00e-50	192.00
IUUC-Mvi-060432	Microbotryum violaceum	31.45	7.00e-53	201.00
IUUC-Mmr-060871	Microcebus murinus	29.33	1.00e-50	193.00
IUUC-Mdo-062301	Monodelphis domestica	29.69	3.00e-50	192.00
IUUC-Mmu-063888	Mus musculus	26.78	2.00e-51	196.00
IUUC-Mac-065137	Musa acuminata	27.50	2.00e-51	195.00
IUUC-Mpu-066732	Mustela putorius furo	31.02	2.00e-49	189.00
IUUC-Mlu-067542	Myotis lucifugus	27.04	8.00e-50	190.00
IUUC-Nfi-068396	Neosartorya fischeri	83.19	0.00e+00	1659.00
IUUC-Ncr-068842	Neurospora crassa	53.39	0.00e+00	1081.00
IUUC-Nle-070156	Nomascus leucogenys	26.62	1.00e-51	196.00
IUUC-Opr-070808	Ochotona princeps	33.33	6.00e-36	144.00
IUUC-Ont-072105	Oreochromis niloticus	26.35	2.00e-48	186.00
IUUC-Ocu-074962	Oryctolagus cuniculus	27.66	7.00e-50	191.00
IUUC-Oba-075178	Oryza barthii	31.39	1.00e-55	209.00
IUUC-Obr-076399	Oryza brachyantha	28.91	1.00e-55	209.00
IUUC-Ogu-078797	Oryza glumaepatula	31.39	1.00e-55	209.00
IUUC-Oin-080085	Oryza indica	31.20	7.00e-48	184.00
IUUC-Olo-081048	Oryza longistaminata	30.82	8.00e-39	154.00
IUUC-Ome-081324	Oryza meridionalis	31.39	1.00e-55	209.00
IUUC-Oni-082548	Oryza nivara	31.39	1.00e-55	209.00
IUUC-Opu-084008	Oryza punctata	32.12	6.00e-56	211.00
IUUC-Oru-084339	Oryza rufipogon	31.39	2.00e-55	209.00
IUUC-Osa-085782	Oryza sativa	31.39	2.00e-55	209.00
IUUC-Ola-087302	Oryzias latipes	27.71	1.00e-42	166.00
IUUC-Olu-087611	Ostreococcus lucimarinus	29.17	3.00e-60	225.00
IUUC-Oga-087935	Otolemur garnettii	31.28	4.00e-49	188.00
IUUC-Oar-089229	Ovis aries	26.72	2.00e-37	149.00
IUUC-Ptr-090715	Pan troglodytes	27.17	4.00e-52	198.00
IUUC-Pan-092318	Papio anubis	27.66	5.00e-51	194.00
IUUC-Psi-094053	Pelodiscus sinensis	27.78	1.00e-49	190.00
IUUC-Pno-094985	Phaeosphaeria nodorum	51.97	0.00e+00	956.00
IUUC-Ppa-095499	Physcomitrella patens	27.16	2.00e-54	205.00
IUUC-Pfo-096857	Poecilia formosa	28.40	9.00e-47	180.00
IUUC-Pab-098047	Pongo abelii	26.80	4.00e-52	198.00
IUUC-Pop-099587	Populus trichocarpa	28.57	3.00e-52	199.00
IUUC-Pca-100558	Procavia capensis	30.84	1.00e-24	107.00
IUUC-Ppe-101261	Prunus persica	29.37	4.00e-54	204.00
IUUC-Pva-102683	Pteropus vampyrus	27.63	6.00e-50	191.00
IUUC-Pgr-103660	Puccinia graminis	36.68	8.00e-59	220.00
IUUC-Ptt-103900	Puccinia triticina	37.43	3.00e-60	224.00
IUUC-Pte-104209	Pyrenophora teres	55.88	0.00e+00	1190.00
IUUC-Pyt-104802	Pyrenophora triticirepentis	56.56	0.00e+00	1186.00
IUUC-Rno-105566	Rattus norvegicus	26.43	2.00e-51	196.00
IUUC-Sce-106291	Saccharomyces cerevisiae	31.59	2.00e-114	404.00
IUUC-Sha-107514	Sarcophilus harrisii	29.95	7.00e-41	160.00
IUUC-Sja-107833	Schizosaccharomyces japonicus	36.16	2.00e-161	561.00
IUUC-Spo-108162	Schizosaccharomyces pombe	35.17	4.00e-158	550.00
IUUC-Ssl-108629	Sclerotinia sclerotiorum	53.30	0.00e+00	696.00
IUUC-Smo-109186	Selaginella moellendorffii	28.31	9.00e-54	203.00
IUUC-Sit-109980	Setaria italica	29.25	7.00e-56	210.00
IUUC-Sly-111547	Solanum lycopersicum	23.43	2.00e-69	255.00
IUUC-Stu-112705	Solanum tuberosum	28.32	1.00e-52	199.00
IUUC-Sar-113222	Sorex araneus	26.85	2.00e-42	166.00
IUUC-Sbi-114528	Sorghum bicolor	28.43	6.00e-58	217.00
IUUC-Sre-115061	Sporisorium reilianum	33.08	2.00e-73	269.00
IUUC-Ssc-116364	Sus scrofa	27.25	9.00e-50	190.00
IUUC-Tgu-116645	Taeniopygia guttata	28.40	4.00e-51	195.00
IUUC-Tru-117590	Takifugu rubripes	28.81	8.00e-49	187.00
IUUC-Tsy-119212	Tarsius syrichta	31.85	6.00e-42	164.00
IUUC-Tni-119915	Tetraodon nigroviridis	28.81	9.00e-49	187.00
IUUC-Tca-121765	Theobroma cacao	23.80	2.00e-70	259.00
IUUC-Tre-121887	Trichoderma reesei	51.19	0.00e+00	1021.00
IUUC-Tvi-122262	Trichoderma virens	51.15	0.00e+00	1011.00
IUUC-Tae-124502	Triticum aestivum	27.76	8.00e-31	126.00
IUUC-Tur-126483	Triticum urartu	28.40	1.00e-55	209.00
IUUC-Tme-127202	Tuber melanosporum	52.17	0.00e+00	959.00
IUUC-Tbe-127350	Tupaia belangeri	25.28	5.00e-25	108.00
IUUC-Ttr-129077	Tursiops truncatus	25.96	7.00e-45	174.00
IUUC-Uma-129465	Ustilago maydis	32.35	1.00e-71	263.00
IUUC-Vda-129844	Verticillium dahliae	53.39	0.00e+00	766.00
IUUC-Vvi-131397	Vitis vinifera	29.93	1.00e-53	203.00
IUUC-Xtr-132057	Xenopus tropicalis	27.31	4.00e-51	194.00
IUUC-Xma-134139	Xiphophorus maculatus	29.97	5.00e-42	164.00
IUUC-Yli-134424	Yarrowia lipolytica	37.87	0.00e+00	648.00
IUUC-Zma-135506	Zea mays	23.81	6.00e-73	267.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence